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Year	Source	Title
2016	NIHR Horizon Scanning Centre (NIHR HSC)	Pembrolizumab (Keytruda) - Hodgkin lymphoma: classical; relapsed or refractory – third and fourth line
2016	Institute for Clinical Effectiveness and Health Policy (IECS)	High-dose chemotherapy followed by autologous transplantation of hematopoietic stem cells in patients with recurrent childhood medulloblastoma
2016	National Institute for Health and Care Excellence (NICE)	Nivolumab in combination with ipilimumab for treating advanced melanoma. NICE technology appraisal guidance 400
2016	Canary Health Service	[Extracorporeal membrane oxygenation (ECMO) in patients with advanced heart failure or cardiogenic shock]
2016	NIHR Health Technology Assessment programme	EQUATOR Network
2016	NIHR Horizon Scanning Centre (NIHR HSC)	Quizartinib - acute myeloid leukaemia: relapsed or refractory; FLT3-internal tandem duplication (ITD) positive – second line
2016	Institute for Clinical Effectiveness and Health Policy (IECS)	Cannabinoids for refractory epilepsy treatment
2016	National Institute for Health and Care Excellence (NICE)	Bosutinib for previously treated chronic myeloid leukaemia. NICE technology appraisal guidance 401
2016	Canary Health Service	[Patient participation in health technology assessment: methodological manual]
2016	NIHR Health Technology Assessment programme	Neuraminidase inhibitors for influenza: a systematic review and meta-analysis of regulatory and mortality data
2016	NIHR Horizon Scanning Centre (NIHR HSC)	Ribociclib with tamoxifen and goserelin, or a non-steroidal aromatase inhibitor and goserelin - breast cancer: advanced; hormone-receptor positive, human epidermal growth factor receptor 2 (HER2) negative; premenopausal women – first line
2016	Institute for Clinical Effectiveness and Health Policy (IECS)	Percutaneous closure of patent foramen ovale for stroke prevention
2016	National Institute for Health and Care Excellence (NICE)	Pemetrexed maintenance treatment for non-squamous non-small-cell lung cancer after pemetrexed and cisplatin. NICE technology appraisal guidance 402
2016	Canary Health Service	[Safety, clinical effectiveness and cost-effectiveness of stereo-electroencephalography in epilepsy surgery]
2016	NIHR Health Technology Assessment programme	Does therapeutic writing help people with long-term conditions? Systematic review, realist synthesis and economic considerations
2016	NIHR Horizon Scanning Centre (NIHR HSC)	Sapacitabine - acute myeloid leukaemia: patients ≥70 years of age; not candidates for standard intensive therapy – first line
2016	Institute for Clinical Effectiveness and Health Policy (IECS)	Activated charcoal for preoperative localization of thyroid cancer recurrence
2016	National Institute for Health and Care Excellence (NICE)	Ramucirumab for previously treated locally advanced or metastatic non-small-cell lung cancer. NICE technology appraisal guidance 403
2016	Canary Health Service	[Prognostic genomic tests for localized prostate cancer]
2016	NIHR Health Technology Assessment programme	Prediction of risk of recurrence of venous thromboembolism following treatment for a first unprovoked venous thromboembolism: systematic review, prognostic model and clinical decision rule, and economic evaluation
2016	NIHR Horizon Scanning Centre (NIHR HSC)	Zoptarelin doxorubicin - endometrial cancer: locally advanced, recurrent or metastatic – second line
2016	Institute for Clinical Effectiveness and Health Policy (IECS)	Cryoablation for the treatment of kidney tumors
2016	National Institute for Health and Care Excellence (NICE)	Degarelix for treating advanced hormone-dependent prostate cancer. NICE technology appraisal guidance 404
2016	NIHR Horizon Scanning Centre (NIHR HSC)	Volanesorsen - familial chylomicronemia syndrome – first line
2016	Institute for Clinical Effectiveness and Health Policy (IECS)	Rituximab biosimilars
2016	National Institute for Health and Care Excellence (NICE)	Trifluridine-tipiracil for previously treated metastatic colorectal cancer. NICE technology appraisal guidance 405
2016	NIHR Health Technology Assessment programme	A systematic review, evidence synthesis and meta-analysis of quantitative and qualitative studies evaluating the clinical effectiveness, the cost-effectiveness, safety and acceptability of interventions to prevent postnatal depression
2016	NIHR Horizon Scanning Centre (NIHR HSC)	Simtuzumab - liver fibrosis secondary to non-alcoholic steatohepatitis or primary sclerosing cholangitis
2016	Institute for Clinical Effectiveness and Health Policy (IECS)	Biomedical treatment for autism spectrum disorders
2016	Canadian Agency for Drugs and Technologies in Health (CADTH)	Anti-vascular endothelial growth factor drugs for the treatment of retinal conditions
2016	National Institute for Health and Care Excellence (NICE)	Crizotinib for untreated anaplastic lymphoma kinase-positive advanced non-small-cell lung cancer. NICE technology appraisal guidance 406
2016	NIHR Horizon Scanning Centre (NIHR HSC)	Teduglutide (Revestive) - short bowel syndrome: in paediatric patients aged 1-17 years who are dependent on parenteral nutrition
2016	Institute for Clinical Effectiveness and Health Policy (IECS)	Use of anti-neuronal antibodies to diagnose paraneoplastic neurological syndromes
2016	National Institute for Health and Care Excellence (NICE)	Secukinumab for active ankylosing spondylitis after treatment with non-steroidal anti-inflammatory drugs or TNF-alpha inhibitors. NICE technology appraisal guidance 407
2016	NIHR Health Technology Assessment programme	A randomised controlled trial of the probiotic Bifidobacterium breve BBG-001 in preterm babies to prevent sepsis, necrotising enterocolitis and death: the Probiotics in Preterm infantS (PiPS) trial
2016	NIHR Health Services and Delivery Research programme	Management by geographical area or management specialised by disorder? A mixed-methods evaluation of the effects of an organisational intervention on secondary mental health care for common mental disorder
2016	NIHR Horizon Scanning Centre (NIHR HSC)	Begelomab (Begesand) - graft versus host disease: acute; steroid resistant – second line
2016	Institute for Clinical Effectiveness and Health Policy (IECS)	Eye tracking speech-generating devices in disorders involving language, speech and motor skills
2016	National Institute for Health and Care Excellence (NICE)	Pegaspargase for treating acute lymphoblastic leukaemia. NICE technology appraisal guidance 408
2016	NIHR Health Technology Assessment programme	An observational study to assess if automated diabetic retinopathy image assessment software can replace one or more steps of manual imaging grading and to determine their cost-effectiveness
2016	NIHR Horizon Scanning Centre (NIHR HSC)	Caplacizumab-Thrombotic thrombocytopenic purpura: acquired; acute phase – adjunctive therapy
2016	Institute for Clinical Effectiveness and Health Policy (IECS)	Riociguat for the treatment of pulmonary hypertension
2016	National Institute for Health and Care Excellence (NICE)	Aflibercept for treating visual impairment caused by macular oedema after branch retinal vein occlusion. NICE technology appraisal guidance 409
2016	NIHR Health Technology Assessment programme	BREATHER (PENTA 16) short-cycle therapy (SCT) (5 days on/2 days off) in young people with chronic human immunodeficiency virus infection: an open, randomised, parallel-group Phase II/III trial
2016	Agency for Healthcare Research and Quality (AHRQ)	Noninvasive testing for coronary artery disease
2016	NIHR Horizon Scanning Centre (NIHR HSC)	Relebactam with imipenem and cilastatin - multi-drug resistant or carbapenem resistant Gram-negative infections
2016	Institute for Clinical Effectiveness and Health Policy (IECS)	Radio-223 (Xofigo®) for the treatment of patients with metastatic cancer
2016	National Institute for Health and Care Excellence (NICE)	Talimogene laherparepvec for treating unresectable metastatic melanoma. NICE technology appraisal guidance 410
2016	Agency for Healthcare Research and Quality (AHRQ)	Improving cultural competence to reduce health disparities
2016	NIHR Horizon Scanning Centre (NIHR HSC)	Autologous haematopoietic stem cell transplantation - multiple sclerosis: relapsing remitting – second line
2016	Institute for Clinical Effectiveness and Health Policy (IECS)	Single-use negative pressure wound therapy for chronic and acute wounds
2016	National Institute for Health and Care Excellence (NICE)	Necitumumab for untreated advanced or metastatic squamous non-small-cell lung cancer. NICE technology appraisal guidance 411
2016	Agency for Healthcare Research and Quality (AHRQ)	Early diagnosis, prevention, and treatment of Clostridium difficile: update
2016	NIHR Horizon Scanning Centre (NIHR HSC)	Low dose desmopressin acetate (Noqdirna) - nocturia: idiopathic nocturnal polyuria; symptomatic; in adults – as sole agent or as a combination treatment
2016	Institute for Clinical Effectiveness and Health Policy (IECS)	Stem cell therapy in heart failure prevention and progress
2016	National Institute for Health and Care Excellence (NICE)	Radium-223 dichloride for treating hormone-relapsed prostate cancer with bone metastases. NICE technology appraisal guidance 412
2016	NIHR Health Technology Assessment programme	An Occupational Therapy intervention for residents with stroke-related disabilities in UK Care Homes (OTCH): cluster randomised controlled trial with economic evaluation
2016	Agency for Healthcare Research and Quality (AHRQ)	Data linkage strategies to advance youth suicide prevention
2016	NIHR Horizon Scanning Centre (NIHR HSC)	Dupilumab - atopic dermatitis: moderate to severe; inadequate response to treatment with topical medications or for whom topical treatments are otherwise medically inadvisable – second line
2016	Institute for Clinical Effectiveness and Health Policy (IECS)	Nivolumab for the treatment of non-small cell lung cancer
2016	National Institute for Health and Care Excellence (NICE)	Elbasvirgrazoprevir for treating chronic hepatitis C. NICE technology appraisal guidance 413
2016	NIHR Health Technology Assessment programme	Antidepressant Controlled Trial For Negative Symptoms In Schizophrenia (ACTIONS): a double-blind, placebo-controlled, randomised clinical trial
2016	Agency for Healthcare Research and Quality (AHRQ)	Nonpharmacologic interventions for agitation and aggression in dementia
2016	Institute for Clinical Effectiveness and Health Policy (IECS)	Nivolumab in advanced melanoma treament
2016	National Institute for Health and Care Excellence (NICE)	Cobimetinib in combination with vemurafenib for treating unresectable or metastatic BRAF V600 mutation-positive melanoma. NICE technology appraisal guidance 414
2016	Agency for Healthcare Research and Quality (AHRQ)	Treatments for fecal incontinence
2016	Institute for Clinical Effectiveness and Health Policy (IECS)	Glifing method to treat dyslexia
2016	Basque Office for Health Technology Assessment (OSTEBA)	[Design and validation of a screening tool for evaluating the health impact of regional policies]
2016	National Institute for Health and Care Excellence (NICE)	Certolizumab pegol for treating rheumatoid arthritis after inadequate response to a TNF-alpha inhibitor. NICE technology appraisal guidance 415
2016	Agency for Healthcare Research and Quality (AHRQ)	Treatment strategies for patients with lower extremity chronic venous disease (LECVD)
2016	Institute for Clinical Effectiveness and Health Policy (IECS)	Magnetic resonance imaging with tractography for brain white matter diseases
2016	Basque Office for Health Technology Assessment (OSTEBA)	[Evaluation of care times for the main cancer sites: colon/rectum, lung, breast and prostate]
2016	National Institute for Health and Care Excellence (NICE)	Nivolumab for previously treated advanced renal cell carcinoma. NICE technology appraisal guidance 417
2016	NIHR Health Technology Assessment programme	The HubBLe Trial: haemorrhoidal artery ligation (HAL) versus rubber band ligation (RBL) for symptomatic second- and third-degree haemorrhoids: a multicentre randomised controlled trial and health-economic evaluation
2016	Agency for Healthcare Research and Quality (AHRQ)	Retinal prostheses in the Medicare population
2016	Institute for Clinical Effectiveness and Health Policy (IECS)	Percutaneous epidural neurolysis and endoscopic neurolysis for the treatment of chronic low back pain
2016	Basque Office for Health Technology Assessment (OSTEBA)	[Impact of the implementation of EFQM in Osakidetza]
2016	National Institute for Health and Care Excellence (NICE)	Dapagliflozin in triple therapy for treating type 2 diabetes. NICE technology appraisal guidance 418
2016	Agency for Healthcare Research and Quality (AHRQ)	Renal denervation in the Medicare Population
2016	Institute for Clinical Effectiveness and Health Policy (IECS)	Trigeminal nerve stimulation to treat neuralgia
2016	Basque Office for Health Technology Assessment (OSTEBA)	[Prevention of Type 2 Diabetes Mellitus in Primary Health Care through healthy lifestyles: care and recommended clinical interventions]
2016	National Institute for Health and Care Excellence (NICE)	Apremilast for treating moderate to severe plaque psoriasis. NICE technology appraisal guidance 419
2016	NIHR Health Technology Assessment programme	Clinical effectiveness and cost-effectiveness of physiotherapy and occupational therapy versus no therapy in mild to moderate Parkinson s disease: a large pragmatic randomised controlled trial (PD REHAB)
2016	NIHR Health Technology Assessment programme	Tackling obesity in areas of high social deprivation: clinical effectiveness and cost-effectiveness of a task-based weight management group programme a randomised controlled trial and economic evaluation
2016	NIHR Health Technology Assessment programme	Adalimumab, etanercept, infliximab, certolizumab pegol, golimumab, tocilizumab and abatacept for the treatment of rheumatoid arthritis not previously treated with disease-modifying antirheumatic drugs and after the failure of conventional disease-modifying antirheumatic drugs only: systematic review and economic evaluation
2016	NIHR Health Technology Assessment programme	Accurate diagnosis of latent tuberculosis in children, people who are immunocompromised or at risk from immunosuppression and recent arrivals from countries with a high incidence of tuberculosis: systematic review and economic evaluation
2016	Institut national d'excellence en sante et en services sociaux (INESSS)	[Levels of care: norms and quality standards]
2016	Institute for Clinical Effectiveness and Health Policy (IECS)	Pembrolizumab for the treatment of advanced melanoma
2016	Basque Office for Health Technology Assessment (OSTEBA)	[Assessment of factors related to the pharmaceutical expenditure in Primary Care, and prescription quality in chronic diseases]
2016	National Institute for Health and Care Excellence (NICE)	Ticagrelor for preventing atherothrombotic events after myocardial infarction. NICE technology appraisal guidance 420
2016	NIHR Health Technology Assessment programme	The Role of Ultrasound Compared to Biopsy of Temporal Arteries in the Diagnosis and Treatment of Giant Cell Arteritis (TABUL): a diagnostic accuracy and cost-effectiveness study
2016	Institut national d'excellence en sante et en services sociaux (INESSS)	[Localized prostate cancer: effectiveness and safety of treatment options]
2016	NIHR Health Technology Assessment programme	The identification and treatment of women with hyperglycaemia in pregnancy: an analysis of individual participant data, systematic reviews, meta-analyses and an economic evaluation
2016	Basque Office for Health Technology Assessment (OSTEBA)	[Impact of the implementation of a population-based cervical cancer screening program based on European recommendations (test/interval) with regard to the current situation]
2016	National Institute for Health and Care Excellence (NICE)	Everolimus with exemestane for treating advanced breast cancer after endocrine therapy. NICE technology appraisal guidance 421
2016	NIHR Health Technology Assessment programme	A multicentre, randomised controlled trial comparing the clinical effectiveness and cost-effectiveness of early nutritional support via the parenteral versus the enteral route in critically ill patients (CALORIES)
2016	Institut national d'excellence en sante et en services sociaux (INESSS)	[Use of the Oncotype DX® test for therapeutic decision-making in the context of treating invasive breast cancer]
2016	NIHR Health Technology Assessment programme	Placental growth factor (alone or in combination with soluble fms-like tyrosine kinase 1) as an aid to the assessment of women with suspected pre-eclampsia: systematic review and economic analysis
2016	Basque Office for Health Technology Assessment (OSTEBA)	[An image-guided system for liver surgery (CAScination)]
2016	Institut für Qualität und Wirtschaftlichkeit im Gesundheitswesen (IQWiG)	[Aclidinium bromide - Benefit assessment according to §35a Social Code Book V]