Original Title: Evaluación de técnicas de neuroimagen (RM/ TC) en el ictus agudo

Authors' objectives: To assess diagnostic validity (accuracy and agreement), safety and efficiency to magnetic resonance imaging perfusion-diffusion mismatch versus computed tomography perfusion in detection of penumbra in ischemic stroke.

Authors' results and conclusions: • The quality of evidence was poor and heterogeneous about agreement and accuracy of MR DWI/PWI mismatch versus CT perfusion. One study was considered moderate methodological quality and 2 studies were considered low quality. These results suggest cautions. • There is limited evidence of accuracy and safety of MR DWI−PWI mismatch versus CT perfusion for penumbra detection in ischemic stroke. •There was disagreement between MR DWI−PWI mismatch and CT perfusion. Therefore, there is no evidence to exchange both techniques or to compare in diagnostic algorithms for acute ischemic stroke and patients who are candidates to fibrinolysis. • For both neuroimaging techniques, comparative evidence from efficiency was not localized. Information to cost and budget impact was not localized. Efficiency analysis is inadequate because absence of effective evidence MR DWI/PWI mismatch versus CT perfusion.

Project Status: Completed

Year Published: 2016

URL for published report: https://www.aetsa.org/publicacion/evaluacion-de-tecnicas-de-neuroimagen-rm-tc-en-el-ictus-agudo/

English language abstract: An English language summary is available

Publication Type: Full HTA

Country: Spain

Organisation Name: Andalusian Health Technology Assessment Area

Contact Address: Area de Evaluacion de Tecnologias Sanitarias Sanitarias de Andalucia (AETSA) Avda. Innovación, s/n Edificio Arena 1. Sevilla (Spain) Tel. +34 955 006 309

Contact Name: aetsa.csalud@juntadeandalucia.es

Contact Email: aetsa.csalud@juntadeandalucia.es

Copyright: Andalusian Health Technology Assessment Area