Authors' recommendations: Soft tissue sarcomas are a group of rare cancers that affect tissues that connect, support and surround other body structures and organs. Soft tissue sarcoma can affect any part of the body including the arms, legs and torso. Soft tissue sarcoma can develop in tissues of fat, muscle, blood vessels, deep skin tissues, tendons and ligaments. NBTXR-3 is a nanoparticle implant that is placed in the tumour to help increase the effects of radiotherapy. It is a new approach to treat people with soft tissue sarcoma of the arm, legs or trunk wall. Some studies have suggested that when NBTXR-3 is used with radiation therapy, it targets the tumour with more energy and causes less damage to the surrounding tissue. A study is now running that is aiming to find out how well NBTXR-3 works and that it is safe to use. If NBTXR-3 is licensed for use in the UK, it can be a new treatment option for people with soft tissue sarcoma.

Project Status: Completed

Year Published: 2016

URL for published report: http://www.hsric.nihr.ac.uk/topics/nbtxr-3-for-advanced-soft-tissue-sarcoma-first-line/

English language abstract: An English language summary is available

Publication Type: Not Assigned

Country: England, United Kingdom

Organisation Name: NIHR Horizon Scanning Centre

Contact Address: The NIHR Horizon Scanning Centre, Department of Public Health, Epidemiology, and Biostatistics, School of Health and Population Sciences, University of Birmingham, 90 Vincent Drive, Edgbaston, Birmingham, B15 2SP. United Kingdom. Tel: +44 121 414 7831, Fax: +44 121 2269

Contact Name: c.packer@bham.ac.uk

Contact Email: c.packer@bham.ac.uk

Copyright: NIHR Horizon Scanning Research&Intelligence Centre (NIHR HSRIC)