Nitric oxide as a treatment of pulmonary hypertension in preterm infants
Respaldiza-Salas MN, Carlos-Gil AM, Navarro-Palenzuela C, Rosario-Lozano MP, Benot-López S.
Record ID 32018000407
Spanish
Original Title:
Óxido nítrico como tratamiento de la hipertensión pulmonar en prematuros.
Authors' objectives:
To evaluate the efficacy, effectiveness, safety and efficiency of iNO in preterm and very preterm infants with pulmonary hypertension due to a respiratory failure.
Authors' results and conclusions:
The available evidence on the efficacy, effectiveness, safety and efficiency of iNO in preterm infants less then 34 weeks of gestational age with respiratory failure HTP is heterogeneous, obtained from studies whose quality is lowmoderate and must consider the results with caution. The iNO showed no benefit compared with treatment with mechanical ventilation in this population. INO treated patients showed improvement of ventilatory parameters not maintained over time. There was no evidence about iNO efficiency. Because of the lack of efficacy or effectivenes of the treatment, makes no sense an economic analysis. Clinical guidelines and consensus documents does not recommend the use of iNO for any indication of preterm less than 34 weeks.
Details
Project Status:
Completed
Year Published:
2016
URL for published report:
https://www.aetsa.org/publicacion/oxido-nitrico-como-tratamiento-de-la-hipertension-pulmonar-en-prematuros/
English language abstract:
An English language summary is available
Publication Type:
Mini HTA
Country:
Spain
MeSH Terms
- Nitric Oxide
- Hypertension, Pulmonary
- Infant, Premature
- Administration, Inhalation
- Infant, Newborn
- Respiratory Distress Syndrome, Newborn
Keywords
- Óxido Nítrico
- Hipertensión pulmonar
- Prematuros
Contact
Organisation Name:
Andalusian Health Technology Assessment Area
Contact Address:
Area de Evaluacion de Tecnologias Sanitarias Sanitarias de Andalucia (AETSA) Avda. Innovación, s/n Edificio Arena 1. Sevilla (Spain) Tel. +34 955 006 309
Contact Name:
aetsa.csalud@juntadeandalucia.es
Contact Email:
aetsa.csalud@juntadeandalucia.es
Copyright:
Andalusian Health Technology Assessment Area
This is a bibliographic record of a published health technology assessment from a member of INAHTA or other HTA producer. No evaluation of the quality of this assessment has been made for the HTA database.