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Year	Source	Title
2016	HAYES, Inc.	Concentrated bone marrow aspirate for spinal surgery
2016	HAYES, Inc.	Disinfection caps with isopropyl alcohol–impregnated sponges for needleless connectors to reduce central line–associated bloodstream infections
2016	HAYES, Inc.	iStent trabecular micro-bypass stent (Glaukos Corp.) in combination with cataract surgery for treatment of open-angle glaucoma
2016	HAYES, Inc.	Maestro Rechargeable System (EnteroMedics Inc.) for vagal blocking for obesity control
2016	HAYES, Inc.	Magnetic resonance–guided focused ultrasound therapy (ExAblate; InSightec Ltd.) for palliation of painful bone metastases
2016	HAYES, Inc.	Nivolumab (Opdivo) for treatment of non-small cell lung cancer
2016	HAYES, Inc.	Pembrolizumab (Keytruda) for unresectable or metastatic melanoma
2016	HAYES, Inc.	Sacubitril-valsartan (Entresto) for heart failure
2016	HAYES, Inc.	Synergy bioabsorbable polymer drug-eluting stent system (Boston Scientific) for treatment of coronary artery disease
2016	HAYES, Inc.	Talimogene laherparepvec (T-VEC; Imlygic) for treatment of unresectable melanoma lesions
2016	HAYES, Inc.	Topera 3D mapping system (RhythmView Workstation and FIRMap) to guide ablation procedures for atrial fibrillation
2016	HAYES, Inc.	Trifluridine-tipiracil (Lonsurf) for refractory metastatic colorectal cancer
2016	HAYES, Inc.	Ustekinumab (Stelara; Janssen Biotech Inc.) for treatment of psoriatic arthritis
2016	NIHR Horizon Scanning Centre (NIHR HSC)	Vepoloxamer for vaso-occlusive crises in sickle cell disease – first line
2016	NIHR Horizon Scanning Centre (NIHR HSC)	Ofatumumab (Arzerra) for refractory follicular lymphoma – third line in combination with bendamustine
2016	NIHR Horizon Scanning Centre (NIHR HSC)	Medidur for non-infectious posterior uveitis – second line
2016	NIHR Horizon Scanning Centre (NIHR HSC)	Epoetin alfa (Eprex) for anaemia in adults with low or intermediate-1 risk myelodysplastic syndromes
2016	NIHR Horizon Scanning Centre (NIHR HSC)	Naldemedine for opioid-induced constipation in adults
2016	NIHR Horizon Scanning Centre (NIHR HSC)	Pegvaliase for the treatment of hyperphenylalaninaemia in adults with phenylketonuria – first line
2016	NIHR Horizon Scanning Centre (NIHR HSC)	KRN23 for X-linked hypophosphataemia in children aged 5-12 years – first line
2016	NIHR Horizon Scanning Centre (NIHR HSC)	Empagliflozin (Jardiance) for preventing cardiovascular death in patients with type 2 diabetes mellitus and high cardiovascular risk
2016	NIHR Horizon Scanning Centre (NIHR HSC)	Empagliflozin (Jardiance) for type 1 diabetes – adjunctive therapy
2016	NIHR Horizon Scanning Centre (NIHR HSC)	Venetoclax with rituximab for relapsed or refractory chronic lymphocytic leukaemia – second and subsequent line
2016	NIHR Horizon Scanning Centre (NIHR HSC)	Pelareorep in combination with paclitaxel for recurrent or persistent epithelial ovarian, fallopian tube or primary peritoneal cancer
2016	NIHR Horizon Scanning Centre (NIHR HSC)	Mogamulizumab for relapsed or refractory cutaneous T-cell lymphoma – second and subsequent lines
2016	NIHR Horizon Scanning Centre (NIHR HSC)	Hexyl aminolevulinate (Cevira) for cervical high-grade squamous intraepithelial lesions
2016	NIHR Horizon Scanning Centre (NIHR HSC)	Crizotinib (Xalkori) for advanced ROS1 positive non-small cell lung cancer – first line
2016	NIHR Horizon Scanning Centre (NIHR HSC)	Aldoxorubicin for metastatic, locally advanced or unresectable soft tissue sarcoma – second line
2016	Agency for Healthcare Research and Quality (AHRQ)	Resident safety practices in nursing home settings
2016	NIHR Public Health Research (PHR) programme	Active for Life Year 5: a cluster randomised controlled trial of a primary school-based intervention to increase levels of physical activity, decrease sedentary behaviour and improve diet
2016	NIHR Health Services and Delivery Research programme	The care of dying people in nursing homes and intensive care units: a qualitative mixed-methods study
2016	NIHR Health Technology Assessment programme	Sepsis: the LightCycler SeptiFast Test MGRADE®, SepsiTest™ and IRIDICA BAC BSI assay for rapidly identifying bloodstream bacteria and fungi – a systematic review and economic evaluation
2016	Agency for Healthcare Research and Quality (AHRQ)	Telehealth: mapping the evidence for patient outcomes from systematic reviews
2016	Agency for Healthcare Research and Quality (AHRQ)	Newer medications for lower urinary tract symptoms attributed to benign prostatic hyperplasia: a review
2016	Agency for Healthcare Research and Quality (AHRQ)	Disparities within serious mental illness
2016	Health Quality Ontario (HQO)	Composite tissue transplant of hand or arm: a health technology assessment
2016	Agenzia nazionale per i servizi sanitari regionali (Agenas)	Sutureless aortic valve replacement (SuAVR) for aortic stenosis
2016	Agenzia nazionale per i servizi sanitari regionali (Agenas)	Implantable Left Ventricular Assist Device (LVAD) in addition to guideline directed medical therapy (GDMT) in end stage heart failure
2016	Agenzia nazionale per i servizi sanitari regionali (Agenas)	Transcatheter implantable devices for mitral valve repair in adults with chronic mitral valve regurgitation
2016	Agenzia nazionale per i servizi sanitari regionali (Agenas)	[Report adaptation: health technology assessment of the different dialysis modalities in Italy]
2016	NIHR Horizon Scanning Centre (NIHR HSC)	Ceritinib (Zykadia) - non-small cell lung cancer: locally advanced or metastatic; anaplastic lymphoma kinase (ALK) positive – first line
2016	NIHR Horizon Scanning Centre (NIHR HSC)	Decitabine (Dacogen) - acute myeloid leukaemia: newly diagnosed de novo or secondary; adult patients of all ages who are not suitable for standard induction chemotherapy
2016	NIHR Horizon Scanning Centre (NIHR HSC)	Pembrolizumab (Keytruda) - colorectal cancer: advanced or metastatic; high-level microsatellite instability – second line
2016	NIHR Horizon Scanning Centre (NIHR HSC)	Pembrolizumab (Keytruda) - Hodgkin lymphoma: classical; relapsed or refractory – third and fourth line
2016	NIHR Horizon Scanning Centre (NIHR HSC)	Quizartinib - acute myeloid leukaemia: relapsed or refractory; FLT3-internal tandem duplication (ITD) positive – second line
2016	NIHR Horizon Scanning Centre (NIHR HSC)	Ribociclib with tamoxifen and goserelin, or a non-steroidal aromatase inhibitor and goserelin - breast cancer: advanced; hormone-receptor positive, human epidermal growth factor receptor 2 (HER2) negative; premenopausal women – first line
2016	NIHR Horizon Scanning Centre (NIHR HSC)	Sapacitabine - acute myeloid leukaemia: patients ≥70 years of age; not candidates for standard intensive therapy – first line
2016	NIHR Horizon Scanning Centre (NIHR HSC)	Zoptarelin doxorubicin - endometrial cancer: locally advanced, recurrent or metastatic – second line
2016	NIHR Horizon Scanning Centre (NIHR HSC)	Volanesorsen - familial chylomicronemia syndrome – first line
2016	NIHR Horizon Scanning Centre (NIHR HSC)	Simtuzumab - liver fibrosis secondary to non-alcoholic steatohepatitis or primary sclerosing cholangitis
2016	NIHR Horizon Scanning Centre (NIHR HSC)	Teduglutide (Revestive) - short bowel syndrome: in paediatric patients aged 1-17 years who are dependent on parenteral nutrition
2016	NIHR Horizon Scanning Centre (NIHR HSC)	Begelomab (Begesand) - graft versus host disease: acute; steroid resistant – second line
2016	NIHR Horizon Scanning Centre (NIHR HSC)	Caplacizumab-Thrombotic thrombocytopenic purpura: acquired; acute phase – adjunctive therapy
2016	NIHR Horizon Scanning Centre (NIHR HSC)	Relebactam with imipenem and cilastatin - multi-drug resistant or carbapenem resistant Gram-negative infections
2016	NIHR Horizon Scanning Centre (NIHR HSC)	Autologous haematopoietic stem cell transplantation - multiple sclerosis: relapsing remitting – second line
2016	NIHR Horizon Scanning Centre (NIHR HSC)	Low dose desmopressin acetate (Noqdirna) - nocturia: idiopathic nocturnal polyuria; symptomatic; in adults – as sole agent or as a combination treatment
2016	NIHR Horizon Scanning Centre (NIHR HSC)	Dupilumab - atopic dermatitis: moderate to severe; inadequate response to treatment with topical medications or for whom topical treatments are otherwise medically inadvisable – second line
2016	NIHR Health Technology Assessment programme	Orthotic management of instability of the knee related to neuromuscular and central nervous system disorders: systematic review, qualitative study, survey and costing analysis
2016	NIHR Public Health Research (PHR) programme	Implications for public health research of models and theories of disability: a scoping study and evidence synthesis
2016	NIHR Health Services and Delivery Research programme	The Prevalence of Visual Impairment in People with Dementia (the PrOVIDe study): a cross-sectional study of people aged 60-89 years with dementia and qualitative exploration of individual, carer and professional perspectives
2016	NIHR Health Services and Delivery Research programme	Determining the optimal model for role substitution in NHS dental services in the UK: a mixed-methods study
2016	Adelaide Health Technology Assessment (AHTA)	Microwave tissue ablation for primary and secondary liver cancer
2016	Institute for Clinical Effectiveness and Health Policy (IECS)	Magnetic resonance spectroscopy and magnetic resonance imaging with tractography for psychiatric disorders
2016	Institute for Clinical Effectiveness and Health Policy (IECS)	Prostate bipolar transurethral resection for the treatment of benign prostatic hyperplasia
2016	Institute for Clinical Effectiveness and Health Policy (IECS)	Eculizumab in nocturnal paroxysmal hemoglobinuria and atypical hemolytic-uremic syndrome
2016	Institute for Clinical Effectiveness and Health Policy (IECS)	Augmentative and alternative communication device with eye tracking (TOBII) in language and motor speech disorders
2016	Institute for Clinical Effectiveness and Health Policy (IECS)	Enzyme replacement therapy in Gaucher Disease
2016	Institute for Clinical Effectiveness and Health Policy (IECS)	Sacubitril in combination with valsartan for chronic heart failure
2016	Institute for Clinical Effectiveness and Health Policy (IECS)	Endoscopic radiofrequency ablation in gastroesophageal reflux disease
2016	Institute for Clinical Effectiveness and Health Policy (IECS)	Ultrasound of peripheral nerves
2016	Institute for Clinical Effectiveness and Health Policy (IECS)	Positron emission tomography/magnetic resonance imaging (PET/MRI) in cancer
2016	Institute for Clinical Effectiveness and Health Policy (IECS)	Ultrasound-guided sclerotherapy with foam in chronic vein insufficiency
2016	Institute for Clinical Effectiveness and Health Policy (IECS)	Anti-mog (myelin oligodendrocyte glycoprotein) antibodies for the diagnosis of optic neuromyelitis and other demyelinating diseases
2016	Institute for Clinical Effectiveness and Health Policy (IECS)	[Alemtuzumab for multiple sclerosis]
2016	Institute for Clinical Effectiveness and Health Policy (IECS)	Brentuximab vedotin in lymphomas
2016	Institute for Clinical Effectiveness and Health Policy (IECS)	Endoscopic radiofrequency ablation (Secca Procedure) for the treatment of fecal incontinence
2016	Institute for Clinical Effectiveness and Health Policy (IECS)	Elastomeric drug infusion pumps
2016	Institute for Clinical Effectiveness and Health Policy (IECS)	Autoantibody panel for autoimmune encephalitis
2016	Institute for Clinical Effectiveness and Health Policy (IECS)	BAHA® bone-anchored hearing aid for the treatment of hearing loss
2016	Institute for Clinical Effectiveness and Health Policy (IECS)	Mutational screening of notch3 gene in the diagnosis of cerebral autosomal dominant arteriopathy with subcortical infarcts and leukocencephalopathy (CADASIL)
2016	Institute for Clinical Effectiveness and Health Policy (IECS)	Radioembolization and chemoembolization with drug-eluting microspheres for the treatment of liver tumors
2016	Institute for Clinical Effectiveness and Health Policy (IECS)	Hyperbaric oxygen therapy for the treatment of idiopathic sudden sensorineural hearing loss
2016	Institute for Clinical Effectiveness and Health Policy (IECS)	Hydrophobic acrylic intraocular lenses in cataract surgery due to uveitis
2016	Institute for Clinical Effectiveness and Health Policy (IECS)	Three-dimensional electroanatomical mapping in arrhythmia ablation
2016	Agency for Healthcare Research and Quality (AHRQ)	Omega-3 fatty acids and cardiovascular disease: an updated systematic review
2016	Agency for Healthcare Research and Quality (AHRQ)	Strategies to de-escalate aggressive behavior in psychiatric patients
2016	Health Quality Ontario (HQO)	Composite tissue transplant of hand or arm: a health technology assessment
2016	Health Quality Ontario (HQO)	Retinal prosthesis system for advanced retinitis pigmentosa: a health technology assessment
2016	Health Quality Ontario (HQO)	Ultrasound as an adjunct to mammography for breast cancer screening: a health technology assessment
2016	Health Quality Ontario (HQO)	Women's experiences of inaccurate breast cancer screening results: a systematic review and qualitative meta-synthesis
2016	Health Quality Ontario (HQO)	Fecal microbiota therapy for clostridium difficile infection: a health technology assessment
2016	Health Quality Ontario (HQO)	Composite tissue transplant of hand or arm: OHTAC recommendation
2016	Health Quality Ontario (HQO)	Retinal prosthesis system for advanced retinitis pigmentosa: OHTAC recommendation
2016	Health Quality Ontario (HQO)	Ultrasound as an adjunct to mammography for breast cancer screening: OHTAC recommendation
2016	Health Quality Ontario (HQO)	Fecal microbiota therapy for clostridium difficile infection: OHTAC recommendation
2016	NIHR Health Technology Assessment programme	Immunosuppressive therapy for kidney transplantation in children and adolescents: systematic review and economic evaluation
2016	Agency for Healthcare Research and Quality (AHRQ)	Renal artery stenosis management strategies: an updated comparative effectiveness review
2016	NIHR Health Services and Delivery Research programme	Improving care for people with dementia: development and initial feasibility study for evaluation of life story work in dementia care
2016	HAYES, Inc.	DecisionDx-UM (Castle Biosciences Inc.)
2016	HAYES, Inc.	Epi proColon (Epigenomics Inc.)