Diclectin (doxylamine succinate and pyridoxine hydrochloride) for the treatment of nausea and vomiting in pregnancy

NIHR HSRIC
Record ID 32016000757
English
Authors' recommendations: Nausea and vomiting in pregnancy, also known as morning sickness, is very common in early pregnancy. It is unpleasant, but usually stops by weeks 16 to 20 of pregnancy. Some women get a very severe form of nausea and vomiting called hyperemesis gravidarum, which can be very serious and needs specialist treatment in hospital. There are currently no medications that are specifically licensed to treat nausea and vomiting in pregnancy, although medications licensed for other diseases can be used. Diclectin is a new drug that is designed to specifically treat nausea and vomiting in pregnancy. Diclectin is being studied to see whether it improves nausea and vomiting in pregnancy and that it is safe to use for pregnant women. If diclectin is licensed for use in the UK, it could provide a new treatment for this unpleasant condition where other non-medical remedies have not worked.
Details
Project Status: Completed
Year Published: 2016
English language abstract: An English language summary is available
Publication Type: Not Assigned
Country: England, United Kingdom
MeSH Terms
  • Dicyclomine
  • Doxylamine
  • Drug Therapy, Combination
  • Female
  • Nausea
  • Vomiting
  • Pregnancy
  • Pyridoxine
Contact
Organisation Name: NIHR Horizon Scanning Centre
Contact Address: The NIHR Horizon Scanning Centre, Department of Public Health, Epidemiology, and Biostatistics, School of Health and Population Sciences, University of Birmingham, 90 Vincent Drive, Edgbaston, Birmingham, B15 2SP. United Kingdom. Tel: +44 121 414 7831, Fax: +44 121 2269
Contact Name: c.packer@bham.ac.uk
Contact Email: c.packer@bham.ac.uk
Copyright: NIHR Horizon Scanning Research&Intelligence Centre (NIHR HSRIC)
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