Vertebral augmentation involving vertebroplasty or kyphoplasty for cancer-related vertebral compression fractures: OHTAC recommendation
Health Quality Ontario
Record ID 32016000759
English
Authors' recommendations:
Clinical Findings
- Vertebral augmentation is associated with a clinically significant reduction in pain, with subsequent decreases in opioid use, improved physical functional disability scores, reduced disability, and improved quality of life.
- These improvements were reported for both vertebroplasty and kyphoplasty and for a diverse group of cancer patients with mixed primary spinal metastatic cancers, multiple myeloma, or hemangiomas.
- The most common adverse event after vertebral augmentation was bone cement leakage, which was usually asymptomatic. Major adverse events following vertebral augmentation rarely occurred.
Economic Findings
- The cost per case for kyphoplasty and vertebroplasty was $7,246 and $3,870, respectively. Compared with non-surgical management, kyphoplasty and vertebroplasty were associated with incremental cost-effectiveness ratios of $33,471 and $17,870, respectively, per quality-adjusted life-year.
- We estimated that the current use of vertebral augmentation procedures cost the Ministry of Health and Long-Term Care about $2.5 million in fiscal year 2014/15 and that more widespread use of these procedures would result in an incremental cost of approximately $67,302 to $913,386, depending on the scenario considered.
The Ontario Health Technology Advisory Committee accepted the findings of the health technology assessment. Given the substantial clinical benefit and the favourable incremental cost-effectiveness ratio OHTAC decided to recommend in favour of public funding.
Details
Project Status:
Completed
Year Published:
2016
URL for published report:
http://www.hqontario.ca/Portals/0/Documents/evidence/reports/recommendation-kyphoplasty-en-1605.pdf
English language abstract:
An English language summary is available
Publication Type:
Not Assigned
Country:
Canada
MeSH Terms
- Humans
- Fractures, Compression
- Kyphoplasty
- Neoplasms
- Spinal Fractures
- Spine
- Vertebroplasty
Contact
Organisation Name:
Health Quality Ontario
Contact Address:
Evidence Development and Standards, Health Quality Ontario, 130 Bloor Street West, 10th floor, Toronto, Ontario Canada M5S 1N5
Contact Name:
EDSinfo@hqontario.ca
Contact Email:
OH-HQO_hta-reg@ontariohealth.ca
Copyright:
Health Quality Ontario (HQO)
This is a bibliographic record of a published health technology assessment from a member of INAHTA or other HTA producer. No evaluation of the quality of this assessment has been made for the HTA database.