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Year Source Title
2025     NIHR Health Technology Assessment programme High-flow nasal cannula therapy versus continuous positive airway pressure for non-invasive respiratory support in paediatric critical care: the FIRST-ABC RCTs
2025     National Institute for Health and Care Excellence (NICE) Balloon disimpaction of the baby's head at emergency caesarean during the second stage of labour. NICE interventional procedures guidance 800
2025     National Institute for Health and Care Excellence (NICE) Pegylated liposomal irinotecan in combination for untreated metastatic pancreatic cancer (terminated appraisal). NICE technology appraisal guidance 1052
2025     National Institute for Health and Care Excellence (NICE) Efanesoctocog alfa for treating and preventing bleeding episodes in haemophilia A in people 2 years and over. NICE technology appraisal guidance 1051
2025     National Institute for Health and Care Excellence (NICE) Ruxolitinib for treating acute graft versus host disease that responds inadequately to corticosteroids in people 12 years and over. NICE technology appraisal guidance 1054
2025     National Institute for Health and Care Excellence (NICE) Cladribine for treating active relapsing forms of multiple sclerosis. NICE technology appraisal guidance 1053
2025     National Institute for Health and Care Excellence (NICE) Relugolix–estradiol–norethisterone for treating symptoms of endometriosis. NICE technology appraisal guidance 1057
2025     National Institute for Health and Care Excellence (NICE) Molnupiravir for treating COVID-19. NICE technology appraisal guidance 1056
2025     National Institute for Health and Care Excellence (NICE) Rucaparib for maintenance treatment of advanced ovarian, fallopian tube and peritoneal cancer after response to first-line platinum-based chemotherapy. NICE technology appraisal guidance 1055
2025     National Institute for Health and Care Excellence (NICE) Tislelizumab in combination for untreated advanced non-small-cell lung cancer (terminated appraisal). NICE technology appraisal guidance 1058
2025     NIHR Health and Social Care Delivery Program Opportunities and practices supporting responsive health care for forced migrants: lessons from transnational practice and a mixed-methods systematic review
2025     NIHR Health and Social Care Delivery Program Approaches used to prevent and reduce the use of restrictive practices on adults with learning disabilities: a realist review
2025     NIHR Health Technology Assessment programme A network approach to addressing the needs of patients with incurable head and neck cancer and their families
2025     NIHR Health and Social Care Delivery Program The effectiveness and cost-effectiveness of the NHS Diabetes Prevention Programme (NHS-DPP): the DIPLOMA long-term multimethod assessment
2025     Penn Medicine Center for Evidence-based Practice (CEP) Alpha-blocking medication before removal of indwelling urinary catheters
2025     NIHR Health and Social Care Delivery Program Optimising neonatal services for very preterm births between 27+0 and 31+6 weeks gestation in England: the OPTI-PREM mixed-methods study
2025     NIHR Health and Social Care Delivery Program Organising general practice for care homes: a multi-method study
2025     HTA South [Ultraviolet light disinfection of flexible endoscopes without working channels: a systematic review and assessment of medical, economical, and organisational aspects]
2025     NIHR Health and Social Care Delivery Program Exploring voluntary sector specialist services for victim-survivors of sexual violence in England: the PROSPER co-production study
2025     NIHR Health and Social Care Delivery Program Direct oral penicillin challenge in secondary care with low-risk patients: the SPACE mixed-methods study with cost-effectiveness analysis
2025     NIHR Health Technology Assessment programme Evaluation of prognostic models to improve prediction of metastasis in patients following potentially curative treatment for primary colorectal cancer: the PROSPECT trial
2025     NIHR Health Technology Assessment programme Supporting self-management with an internet intervention for low back pain in primary care: a RCT (SupportBack 2)
2025     NIHR Health and Social Care Delivery Program Formulating outputs from a mixed-methods study of access to general practice: a series of collaborative stakeholder workshops
2025     NIHR Health Technology Assessment programme Lessons from the PROTECT-CH COVID-19 platform trial in care homes
2025     NIHR Health Technology Assessment programme Stopping anticoagulation for isolated or incidental subsegmental pulmonary embolism: the challenges and lessons from the STOPAPE RCT
2025     NIHR Health Technology Assessment programme Anti-VEGF drugs compared with laser photocoagulation for the treatment of proliferative diabetic retinopathy: a systematic review and individual participant data meta-analysis
2025     NIHR Health Technology Assessment programme A personalised health intervention to maintain independence in older people with mild frailty: a process evaluation within the HomeHealth RCT
2025     NIHR Health Services and Delivery Research programme Multiple Symptoms Study 3 – an extended-role general practitioner clinic for patients with persistent physical symptoms: a randomised controlled trial
2025     NIHR Health Services and Delivery Research programme The impact of redeployment during COVID-19 on nurse well-being, performance and retention: a mixed-methods study (REDEPLOY)
2025     Health Information and Quality Authority (HIQA) National guidelines for the budget impact analysis of health technologies in Ireland
2025     Health Information and Quality Authority (HIQA) National guidelines for the economic evaluation of health technologies in Ireland
2025     National Institute for Health and Care Excellence (NICE) Alcohol-mediated perivascular renal sympathetic denervation for resistant hypertension. NICE interventional procedures guidance 801
2025     National Institute for Health and Care Excellence (NICE) 12 SQ-HDM SLIT for treating allergic rhinitis and allergic asthma caused by house dust mites. NICE technology appraisal guidance 1045
2025     National Institute for Health and Care Excellence (NICE) Atezolizumab for untreated advanced or recurrent non-small-cell lung cancer when platinum-doublet chemotherapy is unsuitable (terminated appraisal). NICE technology appraisal guidance 1047
2025     National Institute for Health and Care Excellence (NICE) Zolbetuximab with chemotherapy for untreated claudin-18.2-positive HER2-negative unresectable advanced gastric or gastro-oesophageal junction adenocarcinoma. NICE technology appraisal guidance 1046
2025     National Institute for Health and Care Excellence (NICE) Fenfluramine for treating seizures associated with Lennox–Gastaut syndrome in people 2 years and over. NICE technology appraisal guidance 1050
2025     National Institute for Health and Care Excellence (NICE) Blinatumomab with chemotherapy for consolidation treatment of Philadelphia-chromosome-negative CD19-positive minimal residual disease-negative B-cell precursor acute lymphoblastic leukaemia. NICE technology appraisal guidance 1049
2025     National Institute for Health and Care Excellence (NICE) Lisocabtagene maraleucel for treating relapsed or refractory large B-cell lymphoma after first-line chemoimmunotherapy when a stem cell transplant is suitable. NICE technology appraisal guidance 1048
2025     NIHR Health Technology Assessment programme A group psychological intervention for postnatal depression in British mothers of South Asian origin – the ROSHNI-2 RCT
2025     NIHR Health Technology Assessment programme Recent research in myalgic encephalomyelitis/chronic fatigue syndrome: an evidence map
2025     NIHR Health Technology Assessment programme Experiences of support to return to work after stroke: longitudinal case studies from RETAKE trial
2025     NIHR Health Technology Assessment programme Gait Rehabilitation for Early rheumatoid Arthritis Trial (GREAT): lessons learnt from a mixed-methods feasibility study and internal pilot trial
2025     Austrian Institute for Health Technology Assessment (AIHTA) Exagamglogene autotemcel (Exa-cel, Casgevy®)
2025     NIHR Health Technology Assessment programme Benefits of aldosterone receptor antagonism in chronic kidney disease: the BARACK-D RCT
2025     Health Sciences Institute in Aragon (IACS) Programme for the use of real world data in health technology assessment: using real-world data for health technology assessment
2025     Penn Medicine Center for Evidence-based Practice (CEP) Dedicated staff for placement of indwelling urinary catheters
2025     NIHR Health Technology Assessment programme The acceptability of blood spot screening and genome sequencing in newborn screening: a systematic review examining evidence and frameworks
2025     NIHR Health Technology Assessment programme Management of diarrhoea in patients with stable ulcerative colitis with low FODMAP diet, amitriptyline, ondansetron or loperamide: the MODULATE RCT
2025     NIHR Health Services and Delivery Research programme The implementation of safety management systems in healthcare: a systematic review and international comparison
2025     Scottish Health Technologies Group (SHTG) Stability of prostate specific antigen (PSA) in blood samples
2025     National Institute for Health and Care Excellence (NICE) Intravascular lithotripsy to treat calcified coronary arteries during percutaneous coronary intervention. NICE interventional procedures guidance 802
2025     National Institute for Health and Care Excellence (NICE) Elacestrant for treating oestrogen receptor-positive HER2-negative advanced breast cancer with an ESR1 mutation after endocrine treatment. NICE technology appraisal guidance 1036
2025     National Institute for Health and Care Excellence (NICE) Pembrolizumab for adjuvant treatment of resected non-small-cell lung cancer. NICE technology appraisal guidance 1037
2025     National Institute for Health and Care Excellence (NICE) Olaparib for treating BRCA mutation-positive HER2-negative advanced breast cancer after chemotherapy. NICE technology appraisal guidance 1040
2025     National Institute for Health and Care Excellence (NICE) Selpercatinib for advanced thyroid cancer with RET alterations untreated with a targeted cancer drug in people 12 years and over. NICE technology appraisal guidance 1039
2025     National Institute for Health and Care Excellence (NICE) Selpercatinib for advanced thyroid cancer with RET alterations after treatment with a targeted cancer drug in people 12 years and over. NICE technology appraisal guidance 1038
2025     National Institute for Health and Care Excellence (NICE) Ganaxolone for treating seizures caused by CDKL5 deficiency disorder in people 2 years and over. NICE technology appraisal guidance 1033
2025     National Institute for Health and Care Excellence (NICE) Selpercatinib for previously treated RET fusion-positive advanced non-small-cell lung cancer. NICE technology appraisal guidance 1042
2025     National Institute for Health and Care Excellence (NICE) Durvalumab with etoposide and either carboplatin or cisplatin for untreated extensive-stage small-cell lung cancer. NICE technology appraisal guidance 1041
2025     National Institute for Health and Care Excellence (NICE) Exagamglogene autotemcel for treating severe sickle cell disease in people 12 years and over. NICE technology appraisal guidance 1044
2025     National Institute for Health and Care Excellence (NICE) Osimertinib for adjuvant treatment of EGFR mutation-positive non-small-cell lung cancer after complete tumour resection. NICE technology appraisal guidance 1043
2025     NIHR Health Technology Assessment programme Understanding the effectiveness and underlying mechanisms of lifestyle modification interventions in adults with learning disabilities: a mixed-methods systematic review
2025     NIHR Health Services and Delivery Research programme Optimisation of the deployment of automated external defibrillators in public places in England
2025     NIHR Health Services and Delivery Research programme Clinical and cost-effectiveness of paramedics working in general practice: a mixed-methods realist evaluation
2025     NIHR Health Technology Assessment programme Establishing palliative care research partnerships in Northern Ireland
2025     NIHR Health Technology Assessment programme Learnings from the establishment and delivery of the UK Collaborative Paediatric Palliative Care Research Network
2025     NIHR Health Technology Assessment programme Interventions that challenge established and accepted clinical practice: lessons learnt from a process evaluation of the STOP-APE trial
2025     NIHR Health Services and Delivery Research programme Cancer in English prisons: a mixed-methods study of diagnosis, treatment, care costs and patient and staff experiences
2025     NIHR Health Services and Delivery Research programme Understanding and addressing factors affecting carers’ mental health during end-of-life caregiving: synopsis of meta synthesis of literature and stakeholder collaboration
2025     NIHR Health Services and Delivery Research programme Intersecting factors of disadvantage and discrimination and their effect on daily life during the coronavirus pandemic: the CICADA-ME mixed-methods study
2025     NIHR Health Technology Assessment programme Stepping into day treatment approach versus inpatient treatment for adults with anorexia nervosa: the DAISIES RCT
2025     NIHR Health Services and Delivery Research programme Improving the experience of health services for trans and gender-diverse young people and their families: an exploratory qualitative study
2025     NIHR Health Services and Delivery Research programme Peer support for adult social care in prisons in England and Wales: a mixed-methods rapid evaluation
2025     NIHR Health Technology Assessment programme Multi-cancer early detection tests for general population screening: a systematic literature review
2025     NIHR Health Technology Assessment programme Development of a clinical decision support tool for Primary care Management of lower Urinary tract Symptoms in men: the PriMUS study
2025     National Institute for Health and Care Excellence (NICE) Transperineal laser ablation for treating lower urinary tract symptoms of benign prostatic hyperplasia. NICE interventional procedures guidance 798
2025     National Institute for Health and Care Excellence (NICE) Electrically stimulated intravesical therapy for interstitial cystitis or overactive bladder in adults. NICE interventional procedures guidance 799
2025     National Institute for Health and Care Excellence (NICE) Tebentafusp for treating advanced uveal melanoma. NICE technology appraisal guidance 1027
2025     National Institute for Health and Care Excellence (NICE) Durvalumab with chemotherapy before surgery (neoadjuvant) then alone after surgery (adjuvant) for treating resectable non-small-cell lung cancer. NICE technology appraisal guidance 1030
2025     National Institute for Health and Care Excellence (NICE) Andexanet alfa for reversing anticoagulation in people with intracranial haemorrhage (terminated appraisal). NICE technology appraisal guidance 1029
2025     National Institute for Health and Care Excellence (NICE) Bimekizumab for treating moderate to severe hidradenitis suppurativa (terminated appraisal). NICE technology appraisal guidance 1028
2025     National Institute for Health and Care Excellence (NICE) Vamorolone for treating Duchenne muscular dystrophy in people 4 years and over. NICE technology appraisal guidance 1031
2025     National Institute for Health and Care Excellence (NICE) Anhydrous sodium thiosulfate for preventing hearing loss caused by cisplatin chemotherapy in people 1 month to 17 years with localised solid tumours. NICE technology appraisal guidance 1034
2025     National Institute for Health and Care Excellence (NICE) Niraparib with abiraterone acetate and prednisone for untreated hormone-relapsed metastatic prostate cancer (terminated appraisal). NICE technology appraisal guidance 1032
2025     National Institute for Health and Care Excellence (NICE) Vadadustat for treating symptomatic anaemia in adults having dialysis for chronic kidney disease. NICE technology appraisal guidance 1035
2025     NIHR Health Technology Assessment programme Public and patient involvement (PPI) in the design, execution and dissemination of a trial: the BISTRO trial
2025     NIHR Health Technology Assessment programme A systematic review of the cost-effectiveness of anti-VEGF drugs for the treatment of diabetic retinopathy
2025     NIHR Health and Social Care Delivery Program Systematic review of integrated mental and physical health services for children and young people with eating and functional symptoms
2024     Agency for Care Effectiveness (ACE) KidneyIntelX for patients with diabetic kidney disease
2024     Agency for Care Effectiveness (ACE) Organ Care System (OCS) Heart System for heart transplantation of marginal brain-death donor hearts or circulatory-death donor hearts
2024     Agency for Care Effectiveness (ACE) RelieVRx for the treatment of chronic lower back pain
2024     Agency for Care Effectiveness (ACE) Canvas Dx to aid the diagnosis of autism spectrum disorder
2024     Agency for Care Effectiveness (ACE) CavaClear for patients with difficult inferior vena cava filters (IVCFs) retrieval who have failed a previous retrieval method
2024     Agency for Care Effectiveness (ACE) Nerivio for the acute and preventive treatment of migraine
2024     Agency for Care Effectiveness (ACE) Transcutaneous afferent patterned stimulation for patients with essential tremor or Parkinsons Disease
2024     NIHR Health Services and Delivery Research programme Routine outcomes to investigate differences between ethnic minorities and white British people presenting to emergency services for injury: the stakeholder consultation
2024     Austrian Institute for Health Technology Assessment (AIHTA) Telehealth in diabetes – EU mapping and systematic evaluation of organisational aspects
2024     Institute for Clinical Effectiveness and Health Policy (IECS) [Botulinum toxin in dystonia, dyspareunia, and strabismus]
2024     Austrian Institute for Health Technology Assessment (AIHTA) Threshold values in health economic evaluations and decision-making
2024     Austrian Institute for Health Technology Assessment (AIHTA) Artificial Intelligence in health care with a focus on hospitals: methodological considerations for health technology assessment: a scoping review