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Year	Source	Title
2015	NIHR Horizon Scanning Centre (NIHR HSC)	Pembrolizumab (Keytruda) for advanced or metastatic urothelial cancer – second line
2015	NIHR Horizon Scanning Centre (NIHR HSC)	Padeliporfin (Tookad soluble) for localised prostate cancer – first line
2015	NIHR Health Technology Assessment programme	An external pilot study to test the feasibility of a randomised controlled trial comparing eye muscle surgery against active monitoring for childhood intermittent exotropia [X(T)]
2015	Institute for Clinical Effectiveness and Health Policy (IECS)	[Pro-BNP Peptide in the diagnosis and prognosis of heart failure]
2015	HAYES, Inc.	Decipher prostate cancer classifier
2015	NIHR Horizon Scanning Centre (NIHR HSC)	Plitidepsin (Aplidin) for relapsed and refractory multiple myeloma – fourth line
2015	NIHR Horizon Scanning Centre (NIHR HSC)	Pegaspargase (Oncaspar) for acute lymphoblastic leukaemia
2015	Institute for Clinical Effectiveness and Health Policy (IECS)	[Assessment on nucleic acid amplification techniques (NAT) for human immunodeficiency, hepatitis C and hepatitis B virus screening in blood banks]
2015	HAYES, Inc.	Autologous fat grafting for breast reconstruction after breast cancer surgery
2015	NIHR Horizon Scanning Centre (NIHR HSC)	Regorafenib (Stivarga) for hepatocellular carcinoma – second line
2015	NIHR Health Technology Assessment programme	The prognostic utility of tests of platelet function for the detection of 'aspirin resistance' in patients with established cardiovascular or cerebrovascular disease: a systematic review and economic evaluation
2015	NIHR Horizon Scanning Centre (NIHR HSC)	Rindopepimut for EGFRvIII positive glioblastoma multiforme - first line
2015	Institute for Clinical Effectiveness and Health Policy (IECS)	[Pharmacogenetic test (Neurofarmagen®) to assess the potential response to drugs and adverse effects in patients with neuropsychiatric disorders]
2015	HAYES, Inc.	DUOPA (carbidopa and levodopa) enteral suspension for treatment of Parkinson's disease
2015	NIHR Horizon Scanning Centre (NIHR HSC)	Ribociclib for advanced hormone receptor positive, HER2 negative breast cancer – first line
2015	NIHR Health Technology Assessment programme	INVESTIGATE-1 (Invasive evaluation before surgical treatment of incontinence gives added therapeutic effect?): A mixed methods study to assess the feasibility of a future randomised controlled trial of invasive urodynamic testing prior to surgery for stress urinary incontinence in women
2015	NIHR Health Technology Assessment programme	Erlotinib and gefitinib for treating non-small cell lung cancer that has progressed following prior chemotherapy (review of NICE technology appraisals 162 and 175): a systematic review and economic evaluation.
2015	NIHR Horizon Scanning Centre (NIHR HSC)	Rociletinib for advanced or recurrent non-small cell lung cancer with the EGFR T790M mutation
2015	Institute for Clinical Effectiveness and Health Policy (IECS)	[Temperature-controlled radiofrequency tissue ablation in obstructive sleep apnea]
2015	HAYES, Inc.	EpiFix (MiMedx Group) for treatment of non-healing wounds
2015	NIHR Horizon Scanning Centre (NIHR HSC)	Selumetinib for KRAS mutation-positive advanced non-small cell lung cancer – second line
2015	Australian Safety and Efficacy Register of New Interventional Procedures -Surgical (ASERNIP-S)	The RePneu Coil System and other bronchoscopic lung volume reduction treatments for advanced emphysema
2015	Institute for Clinical Effectiveness and Health Policy (IECS)	[Endovascular laser treatment of varicose veins of the lower limbs]
2015	HAYES, Inc.	Functional Electrical Stimulation (FES) for treatment of foot drop in multiple sclerosis patients
2015	NIHR Horizon Scanning Centre (NIHR HSC)	Talazoparib for locally advanced and/or metastatic breast cancer with germline BRCA 1/2 positive mutation
2015	Australian Safety and Efficacy Register of New Interventional Procedures -Surgical (ASERNIP-S)	Vagus nerve blocking and gastric artery embolisation for obesity
2015	NIHR Health Technology Assessment programme	The effectiveness and cost-effectiveness of diversion and aftercare programmes for offenders using class A drugs: a systematic review and economic evaluation
2015	NIHR Health Technology Assessment programme	Edoxaban tosylate for the treatment and secondary prevention of deep vein thrombosis and/or pulmonary embolism [ID662]
2015	Institute for Clinical Effectiveness and Health Policy (IECS)	[Nab-paclitaxel (Abraxane) for the treatment of metastatic pancreatic cancer]
2015	HAYES, Inc.	Impella 2.5 system (Abiomed Inc.) for cardiac support in patients undergoing high-risk percutaneous coronary intervention
2015	NIHR Horizon Scanning Centre (NIHR HSC)	Venetoclax for chronic lymphocytic leukaemia with 17p deletion or TP53 mutation
2015	Australian Safety and Efficacy Register of New Interventional Procedures -Surgical (ASERNIP-S)	Barricaid prosthesis for partial annulus replacement
2015	NIHR Health Technology Assessment programme	Enzalutamide for treating metastatic hormone-relapsed prostate cancer not previously treated with chemotherapy
2015	Institute for Clinical Effectiveness and Health Policy (IECS)	[Stem cell transplantation in heart failure]
2015	HAYES, Inc.	Impella 2.5 system (Abiomed Inc.) for emergent hemodynamic cardiac support in patients with cardiogenic shock
2015	NIHR Horizon Scanning Centre (NIHR HSC)	Vincristine liposomal (Marqibo) for relapsed or refractory acute lymphoblastic leukaemia – third line
2015	Australian Safety and Efficacy Register of New Interventional Procedures -Surgical (ASERNIP-S)	ZioPatch for diagnosis of cardiac arrhythmias
2015	Institute for Clinical Effectiveness and Health Policy (IECS)	[Endovascular repair of thoracic and thoraco-abdominal aortic aneurysm]
2015	HAYES, Inc.	Impella 5.0 (Abiomed Inc.) for emergent hemodynamic support in patients with cardiogenic shock
2015	NIHR Horizon Scanning Centre (NIHR HSC)	Vincristine liposomal (Marqibo) in combination with chemotherapy for elderly patients with newly diagnosed CD20 positive diffuse large B-cell lymphoma – first line
2015	Scottish Health Technologies Group (SHTG)	Antimicrobial wound dressings (AWDs) for chronic wounds: Health technology assessment report 13
2015	Australian Safety and Efficacy Register of New Interventional Procedures -Surgical (ASERNIP-S)	ROX Coupler for treatment-resistant hypertension
2015	NIHR Health Technology Assessment programme	Vortioxetine for treating major depressive disorder
2015	NIHR Public Health Research (PHR) programme	Analysis of lower limb movement to determine the effect of manipulating the appearance of stairs to improve safety: a linked series of laboratory-based, repeated measures studies
2015	HAYES, Inc.	Nucleus hybrid L24 cochlear implant system (Cochlear Limited) for hearing loss
2015	NIHR Horizon Scanning Centre (NIHR HSC)	Eprodisate disodium (Kiacta) for AA amyloidosis
2015	Australian Safety and Efficacy Register of New Interventional Procedures -Surgical (ASERNIP-S)	STAR tumour ablation system
2015	NIHR Health Services and Delivery Research programme	Geographical understanding of variation in place of death: the role of care services and end of life care improvement (GUIDE_Care Services)
2015	HAYES, Inc.	Pulsed Electromagnetic Field (PEMF) therapy for treatment of postoperative knee pain and edema
2015	NIHR Horizon Scanning Centre (NIHR HSC)	STG 320 for allergic rhinitis
2015	Australian Safety and Efficacy Register of New Interventional Procedures -Surgical (ASERNIP-S)	Microwave ablation for liver tumours
2015	NIHR Health Services and Delivery Research programme	Impact of a change to remuneration on the technical efficiency of dental practices: evaluation of the pilots of a new NHS Dental Contract in Northern Ireland
2015	HAYES, Inc.	Tandem autologous stem cell transplant for Hodgkin lymphoma
2015	NIHR Horizon Scanning Centre (NIHR HSC)	Cerliponase alfa for neuronal ceroid lipofuscinosis type 2 (CLN2 disease)
2015	Australian Safety and Efficacy Register of New Interventional Procedures -Surgical (ASERNIP-S)	ViewRay System for MRI guided radiotherapy
2015	NIHR Health Technology Assessment programme	Evaluation and validation of social and psychological markers in randomised trials of complex interventions in mental health: a methodological research programme
2015	NIHR Horizon Scanning Centre (NIHR HSC)	Pridopidine (Huntexil) for Huntington's disease
2015	Belgian Health Care Knowledge Centre (KCE)	Percutaneous vertebroplasty and balloon kyphoplasty
2015	Australian Safety and Efficacy Register of New Interventional Procedures -Surgical (ASERNIP-S)	InSpace biodegradable subacromial spacer for the treatment of rotator cuff tears
2015	NIHR Health Services and Delivery Research programme	What are the determinants of variations in emergency readmission rates and one-year mortality in patients hospitalized with heart failure or chronic obstructive pulmonary disease?
2015	Institute for Clinical Effectiveness and Health Policy (IECS)	[Percutaneous Mitral Valve Repair System (MitraClip®) for mitral valve insufficiency]
2015	NIHR Horizon Scanning Centre (NIHR HSC)	Aflibercept solution (Eylea) for visual impairment due to choroidal neovascularisation secondary to pathological myopia
2015	Belgian Health Care Knowledge Centre (KCE)	Cervical and lumbar total disc replacements
2015	Australian Safety and Efficacy Register of New Interventional Procedures -Surgical (ASERNIP-S)	Bioresorbable vascular scaffolds
2015	NIHR Health Technology Assessment programme	Calculating when elective abdominal aortic aneurysm repair improves survival for individual patients: development of the Aneurysm Repair Decision Aid and economic evaluation
2015	Agency for Healthcare Research and Quality (AHRQ)	Use of cardiac resynchronization therapy in the Medicare population
2015	Institute for Clinical Effectiveness and Health Policy (IECS)	[Deep brain stimulation for Parkinson's disease]
2015	NIHR Horizon Scanning Centre (NIHR HSC)	rhNGF for neurotrophic keratitis – first line
2015	Australian Safety and Efficacy Register of New Interventional Procedures -Surgical (ASERNIP-S)	Transcatheter mitral valve replacement for severe mitral regurgitation
2015	NIHR Health Technology Assessment programme	Developing and piloting a peer mentoring intervention to reduce teenage pregnancy in looked-after children and care leavers: an exploratory randomised controlled trial
2015	Institute for Clinical Effectiveness and Health Policy (IECS)	[Intracorneal rings for patients with keratoconus]
2015	NIHR Horizon Scanning Centre (NIHR HSC)	Abatacept for psoriatic arthritis – second line
2015	Australian Safety and Efficacy Register of New Interventional Procedures -Surgical (ASERNIP-S)	Optical coherence tomography (OCT) for retinal assessment in the presence of diabetic macular oedema (DMO) for access to treatment with dexamethasone posterior segment drug delivery system
2015	NIHR Health Technology Assessment programme	Bronchiolitis of Infancy Discharge Study (BIDS): a multicentre, parallel-group, double-blind, randomised controlled, equivalence trial with economic evaluation
2015	Institute for Clinical Effectiveness and Health Policy (IECS)	[Ki-67 proliferative index in patients with early breast cancer]
2015	NIHR Horizon Scanning Centre (NIHR HSC)	Bimagrumab for sporadic inclusion body myositis – first line
2015	Institute for Clinical Effectiveness and Health Policy (IECS)	[Teduglutide for the treatment of patients with short bowel syndrome]
2015	NIHR Horizon Scanning Centre (NIHR HSC)	Remestemcel-L (Prochymal) for steroid refractory acute graft versus host disease – second line
2015	Andalusian Health Technology Assessment Area (AETSA)	[Balloon eustachian tuboplasty for the treatment of eustachian tube dysfunction]
2015	NIHR Public Health Research (PHR) programme	Employer schemes to encourage walking to work: feasibility study incorporating an exploratory randomised controlled trial
2015	Institute for Clinical Effectiveness and Health Policy (IECS)	[Deep brain stimulation in patients with treatment-resistant depressive disorder, obsessive compulsive disorder and Tourette syndrome]
2015	Andalusian Health Technology Assessment Area (AETSA)	[Selection criteria for direct antiviral agents for patients with chronic hepatitis c in the SSPA]
2015	NIHR Health Technology Assessment programme	Use of drug therapy in the management of symptomatic ureteric stones in hospitalised adults: a multicentre, placebo-controlled, randomised controlled trial and cost-effectiveness analysis of a calcium channel blocker (nifedipine) and an alpha-blocker (tamsulosin) (the SUSPEND trial)
2015	NIHR Horizon Scanning Centre (NIHR HSC)	Algisyl-LVR implantable hydrogel (biopolymer) for advanced heart failure
2015	Institute for Clinical Effectiveness and Health Policy (IECS)	[Genomic expression tests in patients with breast cancer: MammaPrint®, Oncotype DX® and Prosigna®]
2015	NIHR Health Technology Assessment programme	The TOMMY trial: a comparison of TOMosynthesis with digital MammographY in the UK NHS Breast Screening Programme - a multicentre retrospective reading study comparing the diagnostic performance of digital breast tomosynthesis and digital mammography with digital mammography alone
2015	Institute for Clinical Effectiveness and Health Policy (IECS)	[Insulin infusion pumps for diabetic patients]
2015	Andalusian Health Technology Assessment Area (AETSA)	[Simeprevir in the treatment of chronic hepatitis C. Comparative efficacy and safety assessment]
2015	Institute for Clinical Effectiveness and Health Policy (IECS)	[Belimumab for the treatment of Systemic Lupus Erythematosus]
2015	NIHR Health Technology Assessment programme	Clinical effectiveness and cost-effectiveness of open and arthroscopic rotator cuff repair (the UK Rotator Cuff Surgery (UKUFF) randomised trial)
2015	NIHR Horizon Scanning Centre (NIHR HSC)	Ranibizumab (Lucentis) for choroidal neovascularisation and macular oedema
2015	Ludwig Boltzmann Institut fuer Health Technology Assessment (LBI-HTA)	[PET-CT: needs assessment for planning]
2015	Institute for Clinical Effectiveness and Health Policy (IECS)	[Denosumab for the treatment of solid tumor bone metástasis]
2015	Institute for Clinical Effectiveness and Health Policy (IECS)	[Fractional flow reserve in coronary artery]
2015	NIHR Health Technology Assessment programme	UK DRAFFT: a randomised controlled trial of percutaneous fixation with Kirschner wires versus volar locking-plate fixation in the treatment of adult patients with a dorsally displaced fracture of the distal radius
2015	NIHR Horizon Scanning Centre (NIHR HSC)	CoSense® End Tidal Carbon Monoxide monitor for neonatal haemolytic disease
2015	Ludwig Boltzmann Institut fuer Health Technology Assessment (LBI-HTA)	[Hadron therapy in children: evidence synthesis for 15 paediatric tumours. Report based on Belgian (KCE) HTA report]
2015	Institute for Clinical Effectiveness and Health Policy (IECS)	[Porcine biological prosthesis for the management of anal fistula]
2015	Institute for Clinical Effectiveness and Health Policy (IECS)	[Corneal collagen crosslinking with riboflavin for keratoconus patients]
2015	NIHR Horizon Scanning Centre (NIHR HSC)	Idarucizumab for the reversal of anticoagulation due to treatment with dabigatran – first line