Authors' objectives: Ulcerative colitis is a type of chronic inflammatory bowel disease that causes ulcers on the lining of the large bowel. Patients suffer with pain and diarrhoea and the condition may deteriorate and lead to hospital admissions. Ulcerative colitis can have a large impact on patients' quality of life. Alicaforsen is a new treatment option that may reduce inflammation in the large bowel. It is taken once a day or once every other day as an enema. Alicaforsen is currently being studied to see how well it works and whether it is safe to use in people with ulcerative colitis. If alicaforsen is licensed for use in the UK, it will offer a new treatment option for people with active ulcerative colitis.

Project Status: Completed

Year Published: 2016

URL for published report: http://www.hsric.nihr.ac.uk/topics/alicaforsen-for-active-ulcerative-colitis-second-line/

English language abstract: An English language summary is available

Publication Type: Not Assigned

Country: England, United Kingdom

Organisation Name: NIHR Horizon Scanning Centre

Contact Address: The NIHR Horizon Scanning Centre, Department of Public Health, Epidemiology, and Biostatistics, School of Health and Population Sciences, University of Birmingham, 90 Vincent Drive, Edgbaston, Birmingham, B15 2SP. United Kingdom. Tel: +44 121 414 7831, Fax: +44 121 2269

Contact Name: c.packer@bham.ac.uk

Contact Email: c.packer@bham.ac.uk

Copyright: NIHR Horizon Scanning Research&Intelligence Centre (NIHR HSRIC)