Concordance in diabetic foot ulceration: a cross-sectional study of agreement between wound swabbing and tissue sampling in infected ulcers

Nelson EA, Wright-Hughes A, Brown S, Lipsky BA, Backhouse M, Bhogal M, Ndosi M, Reynolds C, Sykes G, Dowson C, Edmonds M, Vowden P, Jude EB, Dickie T, Nixon J
Record ID 32011000683
English
Authors' objectives: To determine (1) concordance between culture results from wound swabs and tissue samples from the same ulcer; (2) whether or not differences in bacterial profiles from swabs and tissue samples are clinically relevant; (3) concordance between results from conventional culture versus polymerase chain reaction (PCR); and (4) prognosis for patients with an infected DFU at 12 months' follow-up.
Authors' recommendations: Tissue sampling reported both more pathogens and more organisms overall than swabbing. Both techniques missed some organisms, with tissue sampling missing fewer than swabbing. Results from tissue sampling more frequently led to a (virtual) recommended change in therapy. Long-term prognosis for patients with an infected foot ulcer was poor.
Details
Project Status: Completed
URL for project: http://www.hta.ac.uk/2364
Year Published: 2016
URL for published report: http://www.journalslibrary.nihr.ac.uk/hta/hta20820/#/abstract
English language abstract: An English language summary is available
Publication Type: Not Assigned
Country: England, United Kingdom
MeSH Terms
  • Diabetes Mellitus, Type 2
  • Patient Compliance
  • Patient Education as Topic
  • Self Care
  • Self Efficacy
Contact
Organisation Name: NIHR Health Technology Assessment programme
Contact Address: NIHR Journals Library, National Institute for Health and Care Research, Evaluation, Trials and Studies Coordinating Centre, Alpha House, University of Southampton Science Park, Southampton SO16 7NS, UK
Contact Name: journals.library@nihr.ac.uk
Contact Email: journals.library@nihr.ac.uk
Copyright: <p>2011 Queen's Printer and Controller of HMSO</p>
This is a bibliographic record of a published health technology assessment from a member of INAHTA or other HTA producer. No evaluation of the quality of this assessment has been made for the HTA database.