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Welcome to the international HTA database

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Year Source Title
2015     NIHR Health Technology Assessment programme A randomised controlled trial to assess the clinical effectiveness and cost-effectiveness of alternative treatments to Inhibit VEGF in Age-related choroidal Neovascularisation (IVAN)
2009     NIHR Health Technology Assessment programme Development of a toolkit and glossary to aid in the adaptation of health technology assessment (HTA) reports for use in different contexts
2010     NIHR Health Technology Assessment programme Screening for hyperglycaemia in pregnancy: a rapid update for the National Screening Committee
2011     NIHR Health Technology Assessment programme Ticagrelor for the treatment of acute coronary syndromes
2017     NIHR Health Technology Assessment programme Oral anticoagulants for primary prevention, treatment and secondary prevention of venous thromboembolic disease, and for prevention of stroke in atrial fibrillation: systematic review, network meta-analysis and cost-effectiveness analysis
2020     NIHR Health Technology Assessment programme Adding web-based behavioural support to exercise referral schemes for inactive adults with chronic health conditions: the e-coachER RCT
2023     NIHR Health Technology Assessment programme Mortality impact, risks, and benefits of general population screening for ovarian cancer: the UKCTOCS randomised controlled trial
2010     NIHR Health Technology Assessment programme A pragmatic randomised controlled trial to compare antidepressants with a community-based psychosocial intervention for the treatment of women with postnatal depression: the RESPOND trial
2012     NIHR Health Technology Assessment programme Pulse oximetry as a screening test for congenital heart defects in newborn infants: a test accuracy study with evaluation of acceptability and cost-effectiveness
2009     NIHR Health Technology Assessment programme Colour vision testing for diabetic retinopathy: a systematic review of diagnostic accuracy and economic evaluation
2012     NIHR Health Technology Assessment programme Non-pharmacological interventions to reduce the risk of diabetes in people with impaired glucose regulation: a systematic review and economic evaluation
2011     NIHR Health Technology Assessment programme Eribulin for the treatment of locally advanced or metastatic breast cancer
2017     NIHR Health Technology Assessment programme Randomised controlled trial of silk therapeutic garments for the management of atopic eczema in children: the CLOTHES trial
2018     NIHR Health Technology Assessment programme Understanding variation in ambulance service non-conveyance rates: a mixed methods study
2013     NIHR Health Technology Assessment programme Cancer of Oesophagus or Gastricus - New Assessment of Technology of Endosonography (COGNATE): report of pragmatic randomised trial
2010     NIHR Health Technology Assessment programme Cross-trimester repeated measures testing for Down's syndrome screening: an assessment
2009     NIHR Health Technology Assessment programme Systematic review of the effectiveness and cost-effectiveness of weight management schemes for the under fives: a short report
2011     NIHR Health Technology Assessment programme Adalimumab, etanercept, infliximab, rituximab and abatacept for the treatment of rheumatoid arthritis after the failure of a TNF inhibitor: a systematic review and economic evaluation
2011     NIHR Health Technology Assessment programme Fingolimod for the treatment of relapsing remitting multiple sclerosis
2018     NIHR Health Technology Assessment programme Intramedullary nail fixation versus locking plate fixation for adults with a fracture of the distal tibia: the UK FixDT RCT
2018     NIHR Health Technology Assessment programme The feasibility of early pulmonary rehabilitation and activity after COPD exacerbations: external pilot randomised controlled trial, qualitative case study and exploratory economic evaluation
1998     NIHR Health Technology Assessment programme The costs and benefits of paramedic skills in pre-hospital trauma care
2017     NIHR Health Technology Assessment programme A randomised controlled trial to assess the cost-effectiveness of intensive versus no scheduled follow-up in patients who have undergone resection for colorectal cancer with curative intent
2013     NIHR Health Technology Assessment programme AESOPS: a randomised controlled trial of the clinical effectiveness and cost-effectiveness of opportunistic screening and stepped care interventions for older hazardous alcohol users in primary care
2003     NIHR Health Technology Assessment programme Cannabinoids (cannabis derivatives) for treatment of the symptoms of multiple sclerosis
2011     NIHR Health Technology Assessment programme Tocilizumab for the treatment of systemic juvenile idiopathic arthritis
2017     NIHR Health Technology Assessment programme Is whole-colon investigation by colonoscopy, computerised tomography colonography or barium enema necessary for all patients with colorectal cancer symptoms, and for which patients would flexible sigmoidoscopy suffice? A retrospective cohort study
2005     NIHR Health Technology Assessment programme A randomised controlled trial to compare the cost-effectiveness of tricyclic antidepressants, selective serotonin reuptake inhibitors and lofepramine
2007     NIHR Health Technology Assessment programme A systematic review of quantitative and qualitative research on the role and effectiveness of written information available to patients about individual medicines
2012     NIHR Health Technology Assessment programme The use of MElatonin in children with Neurodevelopmental Disorders and impaired Sleep: a randomised, double-blind, placebo-controlled, parallel study (MENDS)
2011     NIHR Health Technology Assessment programme VenUS III: a randomised controlled trial of therapeutic ultrasound in the management of venous leg ulcers
2011     NIHR Health Technology Assessment programme Denosumab for osteoporotic fractures in post menopausal women primary and secondary prevention
2020     NIHR Health Technology Assessment programme Two speeds of increasing milk feeds for very preterm or very low-birthweight infants: the SIFT RCT
2016     NIHR Health Technology Assessment programme ImmunoCAP® ISAC and Microtest for multiplex allergen testing in people with difficult to manage allergic disease: a systematic review and cost analysis
2010     NIHR Health Technology Assessment programme NESTAC: North of England Study of Tonsillectomy and Adeno-tonsillectomy in children
2005     NIHR Health Technology Assessment programme Clinical effectiveness and cost-effectiveness of immediate angioplasty for acute myocardial infarction: systematic review and economic evaluation
2008     NIHR Health Technology Assessment programme A comparison of the effectiveness and cost-effectiveness of interventions for reducing the lifetime fracture risk in children with juvenile idiopathic arthritis - a systematic review with economic modelling
2014     NIHR Health Technology Assessment programme Randomised controlled trial of Tumour necrosis factor inhibitors Against Combination Intensive Therapy with conventional disease-modifying antirheumatic drugs in established rheumatoid arthritis: the TACIT trial and associated systematic reviews
2010     NIHR Health Technology Assessment programme Computerised decision support systems in order communication for diagnostic, screening or monitoring test ordering: systematic reviews of the effects and cost-effectiveness of systems
2011     NIHR Health Technology Assessment programme Erlotinib monotherapy for the maintenance treatment of non-small cell lung cancer after previous platinum-containing therapy
2019     NIHR Health Technology Assessment programme Tranexamic acid to improve functional status in adults with spontaneous intracerebral haemorrhage: the TICH-2 RCT
2009     NIHR Health Technology Assessment programme Development and randomised controlled trial of dipsticks and diagnostic algorithms for the management of UTI
2008     NIHR Health Technology Assessment programme Accuracy of screening procedures for non-accidental injury in children: systematic review and modelling of clinical effectiveness
2016     NIHR Health Technology Assessment programme TRAPEZE: a randomised controlled trial of the clinical effectiveness and cost-effectiveness of chemotherapy with zoledronic acid, strontium-89, or both, in men with bony metastatic castration-refractory prostate cancer
2011     NIHR Health Technology Assessment programme Etanercept, infliximab and adalimumab for the treatment of psoriatic arthritis: a systematic review and economic evaluation
2013     NIHR Health Technology Assessment programme Dabigatran for the prevention of stroke and systemic embolism in atrial fibrillation: A NICE single technology appraisal
2016     NIHR Health Technology Assessment programme Non-pharmacological treatments for stuttering in children and adults: a systematic review and evaluation of clinical effectiveness, and exploration of barriers to successful outcomes
2020     NIHR Health Technology Assessment programme The association between primary care quality and health-care use, costs and outcomes for people with serious mental illness: a retrospective observational study
2024     NIHR Health Technology Assessment programme A tailored psychological intervention for anxiety and depression management in people with chronic obstructive pulmonary disease: TANDEM RCT and process evaluation
2011     NIHR Health Technology Assessment programme A pragmatic single-blind randomised controlled trial and economic evaluation of the use of leukotriene receptor antagonists in primary care at steps 2 and 3 of the national asthma guidelines (ELEVATE study)
2008     NIHR Health Technology Assessment programme Is a screening programme for early age-related macular degeneration likely to be cost-effective? What are the major areas of uncertainty?
2013     NIHR Health Technology Assessment programme The CRASH-2 trial: a randomised controlled trial and economic evaluation of the effects of tranexamic acid on death, vascular occlusive events and transfusion requirement in bleeding trauma patients
2011     NIHR Health Technology Assessment programme Assessing the surgical skills of trainees in the operating theatre: a prospective observational study of the methodology
2011     NIHR Health Technology Assessment programme Mannitol dry powder for inhalation for the treatment of cystic fibrosis
2013     NIHR Health Technology Assessment programme Does short cycle antiretroviral therapy impact on inflammation, immune activation, thrombogenesis and CD4 cell dynamics?
2022     NIHR Health Technology Assessment programme Liaison Psychiatry: Measurement And Evaluation of Service Types, Referral patterns and Outcomes LP-MAESTRO
2009     NIHR Health Technology Assessment programme ARTISTIC: a randomised trial of human papillomavirus (HPV) testing in primary cervical screening
2004     NIHR Health Technology Assessment programme Systematic review and modelling of the investigation of acute and chronic chest pain presenting in primary care
2007     NIHR Health Technology Assessment programme Systematic reviews of the clinical effectiveness and cost-effectiveness of proton pump inhibitors in acute upper gastrointestinal bleeding
2011     NIHR Health Technology Assessment programme The RATPAC (Randomised Assessment of Treatment using Panel Assay of Cardiac markers) trial: a randomised controlled trial of point-of-care cardiac markers in the emergency department
2010     NIHR Health Technology Assessment programme A systematic review of positron emission tomography (PET) and positron emission tomography/computed tomography (PET/CT) for the diagnosis of breast cancer recurrence
2011     NIHR Health Technology Assessment programme Belimumab for the treatment of active autoantibody-positive systemic lupus erythematosus
2022     NIHR Health Technology Assessment programme Benefits of Aldosterone Receptor Antagonism in Chronic Kidney Disease (BARACK D) Trial
2022     NIHR Health Technology Assessment programme Comparison of ALitretinoin with PUVA as the first line treatment in patients with severe chronic HAnd eczema (ALPHA trial)
2016     NIHR Health Technology Assessment programme Tumour necrosis factor- inhibitors for ankylosing spondylitis and non-radiographic axial spondyloarthritis: a systematic review and economic evaluation
2010     NIHR Health Technology Assessment programme Multi-centre randomised controlled trial examining the cost-effectiveness of contrast-enhanced high field magnetic resonance imaging in women scheduled for wide local excision (COMICE)
2004     NIHR Health Technology Assessment programme The effectiveness and cost-effectiveness of microwave and thermal balloon endometrial ablation for heavy menstrual bleeding: a systematic review and economic modelling
2006     NIHR Health Technology Assessment programme Computed tomography screening for heart disease
2017     NIHR Health Technology Assessment programme The Asymptomatic Carotid Surgery Trial-2 (ACST-2): an ongoing randomised controlled trial comparing carotid endarterectomy with carotid artery stenting to prevent stroke
2011     NIHR Health Technology Assessment programme Palivizumab for immunoprophylaxis of respiratory syncytial virus (RSV) bronchiolitis in high-risk infants and young children: a systematic review and additional economic modelling of subgroup analyses
2011     NIHR Health Technology Assessment programme Fulvestrant for the treatment of locally advanced or metastatic breast cancer
2017     NIHR Health Technology Assessment programme Youth social behaviour and network therapy (Y-SBNT): adaptation of a family and social network intervention for young people who misuse alcohol and drugs a randomised controlled feasibility trial
2022     NIHR Health Technology Assessment programme Early detection of neovascular age-related macular degeneration
2007     NIHR Health Technology Assessment programme Strontium ranelate for the prevention of osteoporotic fractures in post-menopausal women with osteoporosis
2015     NIHR Health Technology Assessment programme Clinical effectiveness and cost-effectiveness of open and arthroscopic rotator cuff repair [the UK Rotator Cuff Surgery (UKUFF) randomised trial]
2011     NIHR Health Technology Assessment programme The clinical effectiveness and cost-effectiveness of different surveillance mammography regimens after the treatment for primary breast cancer: systematic reviews, registry database analyses and economic evaluation
2011     NIHR Health Technology Assessment programme Ofatumumab for the treatment of chronic lymphocytic leukaemia in patients who are refractory to fludarabine and alemtuzumab: a critique of the submission from GSK
2019     NIHR Health Technology Assessment programme Oral versus intravenous antibiotics for bone and joint infections: the OVIVA non-inferiority RCT
2022     NIHR Health Technology Assessment programme Intravenous immunoglobulin in the management of encephalitis in children
2015     NIHR Health Technology Assessment programme The impact of the National Institute for Health Research Health Technology Assessment programme, 2003–13: a multimethod evaluation
2009     NIHR Health Technology Assessment programme A double-blind randomised placebo controlled trial of topical intranasal corticosteroids in 4- to11-year-old children with persistent bilateral otitis media with effusion in primary care
2017     NIHR Health Technology Assessment programme PET-NECK: a multicentre randomised Phase III non-inferiority trial comparing a positron emission tomography computerised tomography-guided watch-and-wait policy with planned neck dissection in the management of locally advanced (N2/N3) nodal metastases in patients with squamous cell head and neck cancer
2011     NIHR Health Technology Assessment programme The clinical effectiveness and cost-effectiveness of long-term weight management schemes for adults: a systematic review
2011     NIHR Health Technology Assessment programme Omalizumab for the treatment of severe persistent allergic asthma in children aged 6-11
2017     NIHR Health Technology Assessment programme A pilot randomised controlled trial of community-led ANtipsychotic Drug REduction for Adults with Learning Disabilities
2018     NIHR Health Technology Assessment programme Partial ablation versus radical prostatectomy in intermediate-risk prostate cancer: the PART feasibility RCT
2010     NIHR Health Technology Assessment programme A multicentred randomised controlled trial of a primary-care based cognitive behavioural programme for low back pain. The Back Skills Training (BeST) trial
2012     NIHR Health Technology Assessment programme Group art therapy as an adjunctive treatment for people with schizophrenia: a randomised controlled trial (MATISSE)
2009     NIHR Health Technology Assessment programme Breastfeeding promotion for infants in neonatal units: a systematic review and economic analysis
2011     NIHR Health Technology Assessment programme The clinical effectiveness and cost-effectiveness of bortezomib and thalidomide in combination regimens with an alkylating agent and a corticosteroid for the first-line treatment of multiple myeloma: a systematic review and economic evaluation
2011     NIHR Health Technology Assessment programme Ranibizumab for the treatment of macular oedema caused by retinal vein occlusion (RVO): a single technology appraisal
2019     NIHR Health Technology Assessment programme Exercise or manual physiotherapy compared with a single session of physiotherapy for osteoporotic vertebral fracture: three-arm PROVE RCT
2017     NIHR Health Technology Assessment programme Subcutaneous Injection of Adalimumab Trial compared with Control (SCIATiC): a randomised controlled trial of adalimumab injection compared with placebo for patients receiving physiotherapy treatment for sciatica
2021     NIHR Health Technology Assessment programme Prognostic tools for identification of high risk in people with Crohn’s disease: systematic review and cost-effectiveness study
2006     NIHR Health Technology Assessment programme A systematic review of the clinical effectiveness, safety, tolerability and cost effectiveness of efalizumab and etanercept within their licensed indications for the treatment of psoriasis. - NICE Technology Assessment Report
2011     NIHR Health Technology Assessment programme EVerT: cryotherapy versus salicylic acid for the treatment of verrucae - a randomised controlled trial
2010     NIHR Health Technology Assessment programme Relapse prevention in UK Stop Smoking Services: current practice, systematic reviews of effectiveness and cost-effectiveness analysis
2012     NIHR Health Technology Assessment programme Dasatinib and nilotinib for imatinib-resistant or -intolerant chronic myeloid leukaemia: a systematic review and economic evaluation
2011     NIHR Health Technology Assessment programme Trabectedin for the treatment of relapsed ovarian cancer
2015     NIHR Health Technology Assessment programme Development of processes allowing near real-time refinement and validation of triage tools during the early stage of an outbreak in readiness for surge: the FLU-CATs Study