A pragmatic single-blind randomised controlled trial and economic evaluation of the use of leukotriene receptor antagonists in primary care at steps 2 and 3 of the national asthma guidelines (ELEVATE study)
Price D, Musgrave S, Wilson E, Sims E, Shepstone L, Blyth A, Murdoch J, Mugford M, Juniper E, Ayres J, Wolfe S, Freeman D, Lipp A, Gilbert R, Harvey I
Record ID 32002000183
English
Authors' recommendations:
Study found that leukotriene antagonists are unlikely to be a cost-effective alternative to inhaled corticosteroids, at 2005 prices, as initial asthma controller therapy at step 2 of the British Thoracic Society (BTS) guidelines, but evidence suggests that they are clinically equivalent to long-acting �2-agonists (LABAs) as add-on to inhaled corticosteroids in terms of quality of life as well as secondary measures; furthermore, they could be an alternative to LABAs at step 3 of the BTS guidelines
Details
Project Status:
Completed
URL for project:
http://www.hta.ac.uk/1204
Year Published:
2011
English language abstract:
An English language summary is available
Publication Type:
Not Assigned
Country:
England, United Kingdom
MeSH Terms
- Clinical Trials, Phase III as Topic
- Primary Health Care
- Randomized Controlled Trials as Topic
- Asthma
- Receptors, Leukotriene
Contact
Organisation Name:
NIHR Health Technology Assessment programme
Contact Address:
NIHR Journals Library, National Institute for Health and Care Research, Evaluation, Trials and Studies Coordinating Centre, Alpha House, University of Southampton Science Park, Southampton SO16 7NS, UK
Contact Name:
journals.library@nihr.ac.uk
Contact Email:
journals.library@nihr.ac.uk
Copyright:
2011 Queen's Printer and Controller of HMSO
This is a bibliographic record of a published health technology assessment from a member of INAHTA or other HTA producer. No evaluation of the quality of this assessment has been made for the HTA database.