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Year	Source	Title
2015	HAYES, Inc.	Adalimumab (humira) for treatment of pediatric Crohn's disease
2015	NIHR Horizon Scanning Centre (NIHR HSC)	Biotin (Cerenday) for permanent disability related to multiple sclerosis relapses – add on therapy to current immunomodulators
2015	NIHR Health Technology Assessment programme	Systematic review, meta-analysis and economic modelling of molecular diagnostic tests for antibiotic resistance in tuberculosis
2015	Belgian Health Care Knowledge Centre (KCE)	Cardiovascular pre-participation screening in young athletes
2015	HAYES, Inc.	Augment bone graft (Wright Medical Group Inc.) for bone regeneration in ankle and/or hindfoot fusions
2015	NIHR Horizon Scanning Centre (NIHR HSC)	Masitinib for amyotrophic lateral sclerosis – add-on therapy to riluzole
2015	NIHR Health Technology Assessment programme	Rapid detection of health-care-associated bloodstream infection in critical care using multipathogen real-time polymerase chain reaction technology: a diagnostic accuracy study and systematic review
2015	Belgian Health Care Knowledge Centre (KCE)	Non-invasive markers of subclinical atherosclerosis for predicting a primary cardiovascular event: a rapid systematic review
2015	HAYES, Inc.	Eliglustat (Cerdelga) for Gaucher disease type 1
2015	NIHR Horizon Scanning Centre (NIHR HSC)	Reslizumab for eosinophilic asthma
2015	NIHR Health Technology Assessment programme	Double-blind randomised controlled trial of percutaneous tibial nerve stimulation versus sham electrical stimulation in the treatment of faecal incontinence: CONtrol of Faecal Incontinence using Distal NeuromodulaTion (the CONFIDeNT trial)
2015	NIHR Public Health Research (PHR) programme	Preschoolers in the Playground: a pilot cluster randomised controlled trial of a physical activity intervention for children aged 18 months to 4 years
2015	HAYES, Inc.	Elosulfase alpha (Vimizim) for treatment of Morquio A Syndrome
2015	NIHR Horizon Scanning Centre (NIHR HSC)	Biotin (Cerenday) for primary and secondary progressive multiple sclerosis - first line
2015	NIHR Health Technology Assessment programme	An open randomised study of autoinflation in 4- to 11-year-old school children with otitis media with effusion in primary care
2015	HAYES, Inc.	Flibanserin (Addyi) for premenopausal women with hypoactive sexual desire disorder
2015	NIHR Horizon Scanning Centre (NIHR HSC)	Sodium zirconium cyclosilicate for hyperkalaemia – first line
2015	The Regional Health Technology Assessment Centre (HTA-centrum)	Endovenous interventions on varicose veins of the leg
2015	Agency for Healthcare Research and Quality (AHRQ)	Menopausal symptoms: comparative effectiveness review of therapies
2015	Agency for Healthcare Research and Quality (AHRQ)	Public reporting of cost measures in health: an environmental scan of current practices and assessment of consumer centeredness
2015	Scottish Health Technologies Group (SHTG)	Magnetic resonance guided focused ultrasound surgery (MRgFUS) for the treatment of uterine fibroids
2015	HAYES, Inc.	iFuse implant system (SI-BONE Inc.) for sacroiliac joint fusion for treatment of low back pain
2015	NIHR Horizon Scanning Centre (NIHR HSC)	Simeprevir in combination with sofosbuvir (with or without ribavirin) for chronic hepatitis C
2015	The Regional Health Technology Assessment Centre (HTA-centrum)	Hypoglossal nerve stimulation (HGNS) for treatment of obstructive sleep apnea
2015	NIHR Health Technology Assessment programme	A multicentre randomised controlled trial and economic evaluation of continuous positive airway pressure for the treatment of obstructive sleep apnoea syndrome in older people: PREDICT
2015	Agency for Healthcare Research and Quality (AHRQ)	Treatments for Fibromyalgia in Adult Subgroups
2015	NIHR Health Services and Delivery Research programme	Evaluating the evidence on employee engagement and its potential benefits to NHS staff: a narrative synthesis of the literature
2015	HAYES, Inc.	Intravenous golimumab (Simponi Aria) for treatment of active rheumatoid arthritis
2015	NIHR Horizon Scanning Centre (NIHR HSC)	Sarilumab for moderate to severe active rheumatoid arthritis
2015	The Regional Health Technology Assessment Centre (HTA-centrum)	Prophylactic insertion of a gastrostomy for nutritional support in patients with head and neck cancer
2015	NIHR Health Technology Assessment programme	Initiating change locally in bullying and aggression through the school environment (INCLUSIVE): a pilot randomised controlled trial
2015	NIHR Health Technology Assessment programme	Blinded randomised controlled trial of low-dose Adjuvant Steroids in Adults admitted to hospital with Pandemic influenza (ASAP): a trial 'in hibernation', ready for rapid activation
2015	Agency for Healthcare Research and Quality (AHRQ)	Pain management injection therapies for low back pain
2015	HAYES, Inc.	Laminotomy for lumbar spinal stenosis
2015	NIHR Horizon Scanning Centre (NIHR HSC)	Tofacitinib for chronic plaque psoriasis – second line
2015	The Regional Health Technology Assessment Centre (HTA-centrum)	Oncological safety and patient-related outcomes of autologous fat grafting in breast reconstruction after breast cancer surgery
2015	NIHR Health Technology Assessment programme	Screening for psychological and mental health difficulties in young people who offend: a systematic review and decision model
2015	Agency for Healthcare Research and Quality (AHRQ)	Routine iron supplementation and screening for iron deficiency anemia in children ages 6 to 24 months: a systematic review to update the U.S. Preventive Services Task Force Recommendation
2015	HAYES, Inc.	Liraglutide (Saxenda) for weight loss in non-diabetic obese adults
2015	NIHR Horizon Scanning Centre (NIHR HSC)	Cx601 (Alofisel®) for complex perianal fistula in adults with non-active or mildly-active luminal Crohn's disease – second line
2015	The Regional Health Technology Assessment Centre (HTA-centrum)	Drug eluting balloons and stents for symptomatic peripheral arterial disease
2015	NIHR Health Technology Assessment programme	A randomised controlled trial and cost-effectiveness analysis of high-frequency oscillatory ventilation against conventional artificial ventilation for adults with acute respiratory distress syndrome. The OSCAR (OSCillation in ARDS) study
2015	NIHR Health Technology Assessment programme	Clinical trial metadata: defining and extracting metadata on the design, conduct, results and costs of 125 randomised clinical trials funded by the National Institute for Health Research Health Technology Assessment programme
2015	Agency for Healthcare Research and Quality (AHRQ)	Management of postpartum hemorrhage
2015	HAYES, Inc.	Lumacaftor-ivacaftor (Orkambi) for treatment of cystic fibrosis
2015	NIHR Horizon Scanning Centre (NIHR HSC)	Tildrakizumab for moderate to severe plaque psoriasis
2015	The Regional Health Technology Assessment Centre (HTA-centrum)	Transcranial Magnetic Resonance Guided Focused Ultrasound treatment of essential tremor, neuropathic pain and Parkinson's disease
2015	NIHR Health Technology Assessment programme	The Cannabinoid Use in Progressive Inflammatory brain Disease (CUPID) trial: a randomised double-blind placebo-controlled parallel-group multicentre trial and economic evaluation of cannabinoids to slow progression in multiple sclerosis
2015	Agency for Healthcare Research and Quality (AHRQ)	Decisional dilemmas in discontinuing prolonged disease-modifying treatment for multiple sclerosis
2015	HAYES, Inc.	Magnetic sphincter augmentation (LINX Reflux Management System) for treatment of gastroesophageal reflux disease
2015	NIHR Horizon Scanning Centre (NIHR HSC)	Natalizumab (Tysabri) for secondary progressive multiple sclerosis
2015	The Regional Health Technology Assessment Centre (HTA-centrum)	Chlorhexidine wash prior to clean surgical procedures
2015	NIHR Health Technology Assessment programme	A randomised controlled trial to assess the clinical effectiveness and cost-effectiveness of alternative treatments to Inhibit VEGF in Age-related choroidal Neovascularisation (IVAN)
2015	NIHR Health Technology Assessment programme	Methods for the estimation of the National Institute for Health and Care Excellence cost-effectiveness threshold
2015	Agency for Healthcare Research and Quality (AHRQ)	Treatments for ankyloglossia and ankyloglossia with concomitant lip-tie
2015	HAYES, Inc.	Nivolumab (Opdivo) for first-line treatment of advanced melanoma
2015	NIHR Horizon Scanning Centre (NIHR HSC)	Clostridium botulinum neurotoxin type A (Xeomin) for sialorrhoea associated with adult Parkinson's disease and paediatric cerebral palsy
2015	NIHR Health Technology Assessment programme	Saline in Acute Bronchiolitis RCT and Economic evaluation: hypertonic saline in acute bronchiolitis - randomised controlled trial and systematic review
2015	NIHR Health Technology Assessment programme	Blinded randomised controlled trial of low-dose Adjuvant Steroids in Adults admitted to hospital with Pandemic influenza (ASAP): a trial in hibernation, ready for rapid activation
2015	NIHR Health Services and Delivery Research programme	Right cot, right place, right time: improving the design and organisation of neonatal care networks – a computer simulation study
2015	HAYES, Inc.	Physical therapy for chronic pelvic pain
2015	NIHR Horizon Scanning Centre (NIHR HSC)	Ticagrelor (Brilique) for preventing thombotic events in patients with acute ischaemic stroke or high risk transient ischaemic attack
2015	The Regional Health Technology Assessment Centre (HTA-centrum)	Home mechanical ventilator treatment for chronic obstructive pulmonary disease patients with chronic hypercapnia
2015	NIHR Health Technology Assessment programme	A randomised controlled trial of Outpatient versus inpatient Polyp Treatment (OPT) for abnormal uterine bleeding
2015	NIHR Health Technology Assessment programme	INVESTIGATE-I (INVasive Evaluation before Surgical Treatment of Incontinence Gives Added Therapeutic Effect?): a mixed-methods study to assess the feasibility of a future randomised controlled trial of invasive urodynamic testing prior to surgery for stress urinary incontinence in women
2015	NIHR Health Services and Delivery Research programme	Patient safety in ambulance services: a scoping review
2015	HAYES, Inc.	Rolapitant (Varubi) in combination with other antiemetic drugs to prevent delayed nausea and vomiting from cancer chemotherapy
2015	NIHR Horizon Scanning Centre (NIHR HSC)	APN311 for high risk neuroblastoma in children and adolescents – first line
2015	NIHR Health Technology Assessment programme	Blinded randomised controlled trial of low-dose Adjuvant Steroids in Adults admitted to hospital with Pandemic influenza (ASAP): a trial in hibernation, ready for rapid activation
2015	NIHR Health Services and Delivery Research programme	An evidence synthesis of risk identification, assessment and management for young people using tier 4 inpatient child and adolescent mental health services
2015	HAYES, Inc.	Use of anti-infliximab antibody levels to monitor infliximab treatment in patients with inflammatory bowel disease (IBD)
2015	NIHR Horizon Scanning Centre (NIHR HSC)	Atezolizumab for urothelial bladder cancer – second and subsequent line
2015	NIHR Public Health Research (PHR) programme	Football Fans in Training (FFIT): a randomised controlled trial of a gender-sensitised weight loss and healthy living programme for men - end of study report
2015	NIHR Health Services and Delivery Research programme	A qualitative and quantitative evaluation of the Advancing Quality pay-for-performance programme in the NHS North West
2015	HAYES, Inc.	Wireless pulmonary artery pressure monitoring with CardioMEMS HF System (St. Jude Medical) for management of chronic heart failure
2015	NIHR Horizon Scanning Centre (NIHR HSC)	Brentuximab vedotin (Adcetris) for CD30-positive cutaneous T-cell lymphoma
2015	NIHR Public Health Research (PHR) programme	Can community-based peer support promote health literacy and reduce inequalities? A realist review
2015	NIHR Health Services and Delivery Research programme	What is the evidence on interventions to manage referral from primary to specialist non-emergency care? A systematic review and logic model synthesis
2015	NIHR Health Technology Assessment programme	The London Exercise And Pregnant smokers (LEAP) trial: a randomised controlled trial of physical activity for smoking cessation in pregnancy with an economic evaluation
2015	HAYES, Inc.	Zio patch (iRhythm Technologies Inc.) for long-term ambulatory cardiac rhythm monitoring
2015	NIHR Horizon Scanning Centre (NIHR HSC)	Buparlisib in combination with fulvestrant for hormone-receptor positive/HER2-negative locally advanced or metastatic breast cancer
2015	NIHR Health Technology Assessment programme	Protocolised Management In Sepsis (ProMISe): a multicentre randomised controlled trial of the clinical effectiveness and cost-effectiveness of early, goal-directed, protocolised resuscitation for emerging septic shock
2015	NIHR Health Services and Delivery Research programme	Translation into British Sign Language and validation of the Strengths and Difficulties Questionnaire
2015	NIHR Health Services and Delivery Research programme	Delivering the aims of the Collaborations for Leadership in Applied Health Research and Care: understanding their strategies and contributions
2015	Agency for Healthcare Research and Quality (AHRQ)	Behavioral counseling and pharmacotherapy interventions for tobacco cessation in adults, including pregnant women: a review of reviews for the U.S. Preventive Services Task Force
2015	HAYES, Inc.	CancerTYPE ID
2015	NIHR Horizon Scanning Centre (NIHR HSC)	Cabozantinib (Cometriq) for metastatic renal cell carcinoma –second line
2015	NIHR Health Technology Assessment programme	Does home oxygen therapy (HOT) in addition to standard care reduce disease severity and improve symptoms in people with chronic heart failure? A randomised trial of home oxygen therapy for patients with chronic heart failure
2015	NIHR Health Services and Delivery Research programme	Evaluating a major innovation in hospital design: workforce implications and impact on patient and staff experiences of all single room hospital accommodation
2015	Agency for Healthcare Research and Quality (AHRQ)	Aspirin use for the prevention of colorectal cancer: an updated systematic evidence review for the U.S. Preventive Services Task Force
2015	HAYES, Inc.	ConfirmMDx for prostate cancer
2015	NIHR Horizon Scanning Centre (NIHR HSC)	Elotuzumab with lenalidomide for multiple myeloma – first line
2015	NIHR Health Technology Assessment programme	The London Exercise And Pregnant smokers (LEAP) trial: a randomised controlled trial of physical activity for smoking cessation in pregnancy with an economic evaluation
2015	NIHR Health Services and Delivery Research programme	Improving practice in safeguarding at the interface between hospital services and children's social care: a mixed-methods case study
2015	Agency for Healthcare Research and Quality (AHRQ)	Aspirin use in adults: cancer, all cause mortality, and harms. A systematic evidence review for the U.S. Preventive Services Task Force
2015	HAYES, Inc.	know error DNA Specimen Provenance Assay (Strand Diagnostics)
2015	NIHR Horizon Scanning Centre (NIHR HSC)	Neratinib with capecitabine for advanced or metastatic HER2-positive breast cancer – third line
2015	NIHR Health Services and Delivery Research programme	Improving community health networks for people with severe mental illness: a case study investigation
2015	Belgian Health Care Knowledge Centre (KCE)	What are the recommended clinical assessment and screening tests during pregnancy?
2015	Agency for Healthcare Research and Quality (AHRQ)	Aspirin use to prevent cardiovascular disease and cancer: a decision analysis