Authors' recommendations: There was evidence to support the diagnostic accuracy of transient elastography compared to liver biopsy for assessing liver fibrosis in the disease areas of interest. - There was evidence that the diagnostic accuracy of FibroTest and acoustic force radiation impulse were not significantly different from transient elastography for assessing liver fibrosis in the disease areas of interest. - There was evidence to support the diagnostic accuracy of controlled attenuation parameter compared to liver biopsy for assessing steatosis in the disease areas of interest. - No evidence was found that assessed the clinical utility of transient elastography (with or without controlled attenuation parameter) versus biopsy, as measured by a change in clinical diagnosis, treatment, or patient outcomes. Beneficial impact could be presumed, given that the accuracy of TE is comparable to that of a biopsy and would have an impact as a noninvasive alternative to diagnose. The clinical utility of CAP is less certain given that treatment for this condition generally consists of providing advice about healthy behaviours.

Project Status: Completed

Year Published: 2015

URL for published report: http://www.hqontario.ca/Portals/0/Documents/eds/ohtas/eba-transient-elastography-1511-en.pdf

English language abstract: An English language summary is available

Publication Type: Not Assigned

Country: Canada

Organisation Name: Health Quality Ontario

Contact Address: Evidence Development and Standards, Health Quality Ontario, 130 Bloor Street West, 10th floor, Toronto, Ontario Canada M5S 1N5

Contact Name: EDSinfo@hqontario.ca

Contact Email: OH-HQO_hta-reg@ontariohealth.ca

Copyright: Health Quality Ontario (HQO)