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Year	Source	Title
2021	Malaysian Health Technology Assessment (MaHTAS)	Therapeutic drug monitoring (TDM) for anti-tuberculosis
2021	Institut für Qualität und Wirtschaftlichkeit im Gesundheitswesen (IQWiG)	[Cabozantinib (renal cell carcinoma) - Benefit assessment according to §35a Social Code Book V]
2021	NIHR Health Technology Assessment programme	High Or Low Dose Syntocinon for delay in labour (HOLDS)
2021	NIHR Health Technology Assessment programme	Modelling tool to support decision-making in the NHS Health Check programme: workshops, systematic review and co-production with users
2021	Health Information and Quality Authority (HIQA)	Review of international ethics frameworks used in policy-making in the context of screening
2021	Malaysian Health Technology Assessment (MaHTAS)	Custodiol HTK as a replacement of blood cardioplegia in cardiac surgery
2021	Institut für Qualität und Wirtschaftlichkeit im Gesundheitswesen (IQWiG)	[Risdiplam (spinal muscular atrophy) - Benefit assessment according to §35a Social Code Book V]
2021	Centre intégré universitaire de santé et de services sociaux de la Capitale-Nationale (CIUSSS)	[Specific rehabilitation interventions for physical impairment to avoid chronification of non-specific back pain in adults]
2021	Institut national d'excellence en sante et en services sociaux (INESSS)	[State of knowledge: efficacy and safety of onasemnogene abeparvovec, nusinersen and risdiplam for the treatment of spinal muscular atrophy]
2021	Canadian Agency for Drugs and Technologies in Health (CADTH)	Prevention of tuberculosis reactivation
2021	Malaysian Health Technology Assessment (MaHTAS)	Mobile C-arm fluoroscopy for cardiothoracic surgery
2021	Institut für Qualität und Wirtschaftlichkeit im Gesundheitswesen (IQWiG)	[Nivolumab (renal cell carcinoma) - Benefit assessment according to §35a Social Code Book V]
2021	NIHR Health Technology Assessment programme	Cognitive therapy compared with CBT for social anxiety disorder in adolescents: a feasibility study
2021	Penn Medicine Center for Evidence-based Practice (CEP)	Opioids for vaso-occlusive crisis in pregnant patients
2021	NIHR Health Technology Assessment programme	Improving continence in children and young people with neurodisability: a systematic review and survey
2021	Institut für Qualität und Wirtschaftlichkeit im Gesundheitswesen (IQWiG)	[Esketamine (depression, acute treatment) - Addendum to Commission A21-25]
2021	Haute Autorite de sante (HAS)	[Remote monitoring of patients with an implantable loop recorder]
2021	Penn Medicine Center for Evidence-based Practice (CEP)	COVID-19: vaccination for women who are pregnant or lactating
2021	Institut national d'excellence en sante et en services sociaux (INESSS)	[Report: assessment of the relevance of newborn screening for spinal muscular atrophy]
2021	Institut für Qualität und Wirtschaftlichkeit im Gesundheitswesen (IQWiG)	[Avelumab (urothelial carcinoma) - Addendum to Commission A21-23]
2021	Penn Medicine Center for Evidence-based Practice (CEP)	COVID-19: management of vaccine-associated thrombotic syndromes
2021	Swiss Federal Office of Public Health (FOPH)	Effectiveness and safety of vitamin B12 tests
2021	Canadian Agency for Drugs and Technologies in Health (CADTH)	Yttrium-90 microspheres for intermediate- or advanced-stage hepatocellular carcinoma
2021	Malaysian Health Technology Assessment (MaHTAS)	Viscoelastic haemostatic assay for non-cardiac surgery
2021	Institut für Qualität und Wirtschaftlichkeit im Gesundheitswesen (IQWiG)	[Relationship between volume of services and quality of treatment outcome for stem cell transplantation - Update of commission V18-02]
2021	German Agency for Health Technology Assessment at the German Institute for Medical Documentation and Information (DAHTA DIMDI)	[Gender-specific differences in drug effects. Exemplary analysis based on beta-adrenoceptor antagonists as cardiac therapy and antidepressants as psychotropic drugs]
2021	Institut national d'excellence en sante et en services sociaux (INESSS)	[Report: advisability of using molecular tests to clarify the diagnosis of thyroid nodules with indeterminate cytology]
2021	Institut national d'excellence en sante et en services sociaux (INESSS)	[State of knowledge: efficacy and safety of buprenorphine and methadone for the treatment of opioid use disorder]
2021	Andalusian Health Technology Assessment Area (AETSA)	[Laser interstitial thermal therapy for patients with refractory epilepsy: safety and effectiveness. A systematic review]
2021	Institut für Qualität und Wirtschaftlichkeit im Gesundheitswesen (IQWiG)	[Evidence report for the S3 guideline on clinical nutrition in gastroenterology - Pancreas: timing of nutrition in acute pancreatitis]
2021	Health Information and Quality Authority (HIQA)	The identification and review of new and updated public health guidance - COVID-19
2021	German Agency for Health Technology Assessment at the German Institute for Medical Documentation and Information (DAHTA DIMDI)	[Smoking bans in public places]
2021	NIHR Health Technology Assessment programme	CONservative TReatment of Appendicitis in Children a randomised controlled Trial CONTRACT (Feasibility study)
2021	Institut national d'excellence en sante et en services sociaux (INESSS)	[State of knowledge: challenging behaviours - best practices in prevention, assessment and Intervention for people with an intellectual disability, physical disability or autism spectrum disorder]
2021	Institut national d'excellence en sante et en services sociaux (INESSS)	[State of practice: care pathways leading to the diagnostic assessment of neurodevelopmental disorders in children 0-7 years old]
2021	Institut für Qualität und Wirtschaftlichkeit im Gesundheitswesen (IQWiG)	[Evidence report for the S3 guideline on clinical nutrition in gastroenterology - Pancreas: nutritional interventions in chronic pancreatitis]
2021	Health Information and Quality Authority (HIQA)	Duration of protective immunity following COVID-19 vaccination (efficacy and effectiveness)
2021	NIHR Health Services and Delivery Research programme	Acute day units in non-residential settings for people in mental health crisis: the AD-CARE mixed-methods study
2021	Institut national d'excellence en sante et en services sociaux (INESSS)	[Guidelines and standards: oral opioid agonists for the treatment of opioid use disorder]
2021	Institut national d'excellence en sante et en services sociaux (INESSS)	[Report: relevance of and indications for submitting surgical specimens to the anatomic pathology laboratory: obstetrics/gynecology and urology]
2021	Canadian Agency for Drugs and Technologies in Health (CADTH)	Abiraterone acetate for metastatic castration-sensitive prostate cancer
2021	Institut für Qualität und Wirtschaftlichkeit im Gesundheitswesen (IQWiG)	[Obinutuzumab (chronic lymphocytic leukaemia) - Benefit assessment according to §35a Social Code Book V]
2021	Canadian Agency for Drugs and Technologies in Health (CADTH)	Remote monitoring programs for cardiac conditions
2021	Penn Medicine Center for Evidence-based Practice (CEP)	COVID-19: effects of vaccines on fertility and pregnancy outcomes
2021	Institut national d'excellence en sante et en services sociaux (INESSS)	[Report: relevance of and indications for submitting surgical specimens to the anatomic pathology laboratory: general surgery, plastic surgery and dermatology]
2021	Canadian Agency for Drugs and Technologies in Health (CADTH)	Bisphosphonate drugs for the treatment of osteoporosis in post-menopausal women
2021	Institut für Qualität und Wirtschaftlichkeit im Gesundheitswesen (IQWiG)	[Obinutuzumab (follicular lymphoma, after rituximab) - Benefit assessment according to §35a Social Code Book V]
2021	German Agency for Health Technology Assessment at the German Institute for Medical Documentation and Information (DAHTA DIMDI)	[Radiation exposure by medical X-ray applications]
2021	NIHR Health Technology Assessment programme	Minimally invasive thoracoscopically-guided right minithoracotomy versus conventional sternotomy for mitral valve repair: a multicentre randomised controlled trial (UK Mini Mitral)
2021	Institut national d'excellence en sante et en services sociaux (INESSS)	[State of knowledge: organization of care and services related to alternate levels of care (ALC)]
2021	Institut national d'excellence en sante et en services sociaux (INESSS)	[Guidelines and standards: optimal use of immunoglobulins in infectious diseases]
2021	Canadian Agency for Drugs and Technologies in Health (CADTH)	Direct oral anticoagulants for atrial fibrillation [evidence update]
2021	Institut für Qualität und Wirtschaftlichkeit im Gesundheitswesen (IQWiG)	[Isatuximab (multiple myeloma after >= 1 prior therapy, combination with carfilzomib und dexamethasone) - Benefit assessment according to §35a Social Code Book V]
2021	German Agency for Health Technology Assessment at the German Institute for Medical Documentation and Information (DAHTA DIMDI)	[Music therapy for adolescents with mental and behavioural disorders]
2021	Institut national d'excellence en sante et en services sociaux (INESSS)	[State of practice: portrait of the use of home care and support services by people at the end-stages of life in Québec, 2013-2018]
2021	Canadian Agency for Drugs and Technologies in Health (CADTH)	Interventions to address and prevent violence toward health care workers in the emergency department
2021	Institut für Qualität und Wirtschaftlichkeit im Gesundheitswesen (IQWiG)	[Isatuximab (multiple myeloma after >= 2 prior therapies, combination with pomalidomide and dexamethasone) - Benefit assessment according to §35a Social Code Book V]
2021	Agencia de Evaluacion de Tecnologias Sanitarias (AETS)	[Sentinel lymph node biopsy in oral cavity carcinoma: clinical effectiveness, safety, and cost-effectiveness]
2021	Health Information and Quality Authority (HIQA)	An international review: Policies relating to healthcare personnel who do not avail of COVID-19 vaccination
2021	German Agency for Health Technology Assessment at the German Institute for Medical Documentation and Information (DAHTA DIMDI)	[Effects of life style changes in persons with prediabetes]
2021	NIHR Health Technology Assessment programme	Understanding health-care outcomes of older people with cognitive impairment and/or dementia admitted to hospital: a mixed-methods study
2021	NIHR Health Technology Assessment programme	Antidepressant medication to prevent depression relapse in primary care: the ANTLER RCT
2021	The Federal Joint Committee (G-BA)	[Pharmaceutical Directive/Annex XII: Amikacin (Mycobacterium avium complex pulmonary infections)]
2021	Canadian Agency for Drugs and Technologies in Health (CADTH)	Hybrid closed-loop insulin delivery systems for people with Type 1 diabetes
2021	Health Technology Wales (HTW)	Transcranial magnetic stimulation for the treatment of depression
2021	Institut für Qualität und Wirtschaftlichkeit im Gesundheitswesen (IQWiG)	[Onasemnogene abeparvovec (spinal muscular atrophy) - Benefit assessment according to §35a Social Code Book V]
2021	Health Information and Quality Authority (HIQA)	Evidence synthesis for groups in vaccine allocation group nine - those aged 18-64 years living or working in crowded conditions
2021	German Agency for Health Technology Assessment at the German Institute for Medical Documentation and Information (DAHTA DIMDI)	[Mistletoe therapy with breast cancer]
2021	The Federal Joint Committee (G-BA)	[Pharmaceutical Directive/Annex XII: Atidarsagen autotemcel (metachromatic leukodystrophy with biallelic mutation in the ARSA gene)]
2021	Institut für Qualität und Wirtschaftlichkeit im Gesundheitswesen (IQWiG)	[Cannabidiol (seizures in tuberous sclerosis complex) - Assessment according to §35a (para. 1., sentence 11) Social Code Book V]
2021	Agencia de Evaluacion de Tecnologias Sanitarias (AETS)	[Systematic review about effectiveness of digital pathology as a diagnostic tool for pathology and cytopathology]
2021	Health Information and Quality Authority (HIQA)	Advice to the National Public Health Emergency Team: Derogation of healthcare workers, who are deemed close contacts, from restricted movements following COVID-19 vaccination
2021	German Agency for Health Technology Assessment at the German Institute for Medical Documentation and Information (DAHTA DIMDI)	[Coping strategies in complex medical situations - the example of coronary heart disease]
2021	NIHR Health Services and Delivery Research programme	Models of generalist and specialist care in smaller acute hospitals: an exploratory study
2021	Institut national d'excellence en sante et en services sociaux (INESSS)	[Report: noninvasive fetal RhD genotyping using maternal plasma]
2021	Scottish Health Technologies Group (SHTG)	Detection of paroxysmal atrial fibrillation in patients with newly diagnosed ischaemic stroke
2021	The Federal Joint Committee (G-BA)	[Pharmaceutical Directive/Annex XII: Autologous anti-CD19-transduced CD3+ cells (mantle cell lymphoma, pretreated patients)]
2021	The National Health Care Institute (ZIN, Zorginstituut Nederland)	Package advice ravulizumab (Ultomiris®) for the treatment of PNH and aHUS
2021	Institut für Qualität und Wirtschaftlichkeit im Gesundheitswesen (IQWiG)	[Obinutuzumab (follicular lymphoma, first line) - Benefit assessment according to §35a Social Code Book V]
2021	Health Information and Quality Authority (HIQA)	Public health measures and strategies to limit the spread of COVID-19: an international review [Update]
2021	German Agency for Health Technology Assessment at the German Institute for Medical Documentation and Information (DAHTA DIMDI)	[The potential influence of socio-demographical factors on access to and results of rehabilitation]
2021	The Federal Joint Committee (G-BA)	[Pharamceutical Directive/Annex XII: Avapritinib (gastrointestinal stromal tumours)]
2021	The National Health Care Institute (ZIN, Zorginstituut Nederland)	GVS advice tirbanibulin (Klisyri®) for the treatment of adults with actinic keratosis
2021	Institut für Qualität und Wirtschaftlichkeit im Gesundheitswesen (IQWiG)	[Tucatinib (breast cancer) - Addendum to Commission A21-26]
2021	Health Information and Quality Authority (HIQA)	Public health measures and strategies to limit the spread of COVID-19: an international review: Antigen testing in asymptomatic individuals in community settings
2021	The National Health Care Institute (ZIN, Zorginstituut Nederland)	Package advice venetoclax (Venclyxto®)
2021	Institut für Qualität und Wirtschaftlichkeit im Gesundheitswesen (IQWiG)	[Lanadelumab (hereditary angioedema) - Benefit assessment according to §35a Social Code Book V]
2021	Health Information and Quality Authority (HIQA)	Current public health guidance for community settings and infection prevention and control measures in healthcare settings for COVID-19: a rapid review
2021	Canadian Agency for Drugs and Technologies in Health (CADTH)	Stereotactic ablative radiotherapy for the treatment of oligometastatic cancer: a clinical review as part of a health technology assessment v1.0
2021	The National Health Care Institute (ZIN, Zorginstituut Nederland)	GVS assessment ponesimod (Ponvory®) for the treatment of relapsing forms of multiple sclerosis (RMS)
2021	Institut für Qualität und Wirtschaftlichkeit im Gesundheitswesen (IQWiG)	[Evidence report for the S3 guideline on clinical nutrition in gastroenterology - Pancreas: nutritional supplementation in acute pancreatitis]
2021	German Agency for Health Technology Assessment at the German Institute for Medical Documentation and Information (DAHTA DIMDI)	[Speech therapy for aphasia]
2021	Swiss Federal Office of Public Health (FOPH)	Statins in the primary prevention of cardiovascular events and mortality in Switzerland
2021	NIHR Health Technology Assessment programme	Testing strategies for Lynch syndrome in people with endometrial cancer: systematic reviews and economic evaluation
2021	Institut national d'excellence en sante et en services sociaux (INESSS)	[Report: microbiological stool testing in adults and children with diarrhea: relevance and measures to promote judicious use]
2021	The National Health Care Institute (ZIN, Zorginstituut Nederland)	Package advice cemiplimab (Libtayo®) for the treatment of non-small cell lung carcinoma (NSCLC)
2021	Institut für Qualität und Wirtschaftlichkeit im Gesundheitswesen (IQWiG)	[Pembrolizumab (Hodgkin lymphoma) - Addendum to Commission A21-35]
2021	Swiss Federal Office of Public Health (FOPH)	Vertebroplasty or kyphoplasty in painful osteoporotic vertebral compression fractures unresponsive to non-surgical treatment
2021	Institut national d'excellence en sante et en services sociaux (INESSS)	[Report: pertussis - diagnostic modalities and trajectory]
2021	The National Health Care Institute (ZIN, Zorginstituut Nederland)	GVS assessment empagliflozin (Jardiance®) for the treatment of adults with chronic heart failure