Helicobacter pylori eradication for primary prevention of peptic ulcer bleeding in older patients prescribed aspirin in primary care (HEAT): a randomised, double-blind, placebo-controlled trial
Hawkey C, Avery A, Coupland CA, Crooks C, Dumbleton J, Hobbs FD, Kendrick D, Moore M, Morris C, Rubin G, Smith M, Stevenson D, HEAT Trialists
Record ID 32012000321
English
Original Title:
Helicobacter eradication to prevent ulcer bleeding in aspirin users: a large simple randomised controlled trial (HEAT)
Authors' objectives:
Peptic ulcers in patients receiving aspirin are associated with Helicobacter pylori infection. We aimed to investigate whether H pylori eradication would protect against aspirin-associated ulcer bleeding.
Details
Project Status:
Completed
URL for project:
https://www.journalslibrary.nihr.ac.uk/programmes/hta/095552/#/
Year Published:
2022
URL for published report:
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(22)01843-8/fulltext
Requestor:
NIHR Health Technology Assessment programme
English language abstract:
An English language summary is available
Publication Type:
Full HTA
Country:
England, United Kingdom
MeSH Terms
- Anti-Bacterial Agents
- Aspirin
- Helicobacter pylori
- Helicobacter Infections
- Peptic Ulcer Hemorrhage
- Peptic Ulcer
- Clarithromycin
Contact
Organisation Name:
NIHR Health Technology Assessment programme
Contact Address:
NIHR Journals Library, National Institute for Health and Care Research, Evaluation, Trials and Studies Coordinating Centre, Alpha House, University of Southampton Science Park, Southampton SO16 7NS, UK
Contact Name:
journals.library@nihr.ac.uk
Contact Email:
journals.library@nihr.ac.uk
This is a bibliographic record of a published health technology assessment from a member of INAHTA or other HTA producer. No evaluation of the quality of this assessment has been made for the HTA database.