Original Title: Kirurgiske prosedyrer for behandling av sykelig overvekt: fullstendig metodevurdering

Authors' objectives: Norwegian Institute of Public Health (NIPH) was commissioned to carry out a HTA comparing the effectiveness of different surgical procedures for the treatment of obesity among adults. Efficacy and safety are previously described in a report that follows from a collaboration between NIPH and EUnetHTA. The current report summarises the EUnetHTA report and adds health economic aspects of surgical procedures in a Norwegian context. The HTA compares the following surgical procedures: AGB, SG, RYGB, OAGB, D-RYGB, BPD-DS, BPD, B-RYGB and B-SG. The primary outcomes were weight, diabetes status, quality of life and mortality.

Authors' results and conclusions: We conducted systematic searches for randomized controlled trials and conducted network meta-analyzes to analyze weight and diabetes outcome at 2, 3, and 5 years of follow-up. We included 22 efficacy studies comprising 7 surgical procedures and 11 comparisons. 27 studies provided data on safety. It is uncertain whether there is any difference in the risk of early mortality between different types of surgical procedures for the treatment of obesity. It is uncertain whether there is any difference in effect on weight status between different surgical procedures for treatment of obesity. There may be little or no difference in the effect on diabetes status between different surgical procedures for treatment of obesity. There may be little or no difference in the effect on HRQOL between different types of surgery for treatment of obesity. The differences in costs between the surgical procedures most communly used in Norway are negligible, and since the current evidence suggests that the choice of procedure has limited impact on the outcomes with greatest impact on cost-effectiveness, we have not conducted a comprehensive health economic analysis.

Project Status: Completed

Year Published: 2022

URL for published report: https://www.fhi.no/en/publ/2022/Surgical-procedures-for-treatment-of-obesity/

English language abstract: An English language summary is available

Publication Type: Full HTA

Country: Norway

Organisation Name: Norwegian Institute of Public Health

Contact Address: P.O. Box 222 Skoyen, N-0123, Oslo