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Year	Source	Title
2022	NIHR Health Technology Assessment programme	A large randomised assessment of the relative cost-effectiveness of different classes of drugs for Parkinson's disease (PD MED)
2022	Medical Services Advisory Committee (MSAC)	Genetic testing for childhood hearing impairment
2022	Medical Services Advisory Committee (MSAC)	Two testing options for determining eligibility for access to Pharmaceutical Benefits Schedule-subsidised aducanumab in patients with early stage Alzheimer disease
2022	NIHR Health Technology Assessment programme	Multicentre UK study of the acetylcholinesterase inhibitor donepezil in early dementia associated with Parkinson's disease (MUSTARDD-PD)
2022	NIHR Health Technology Assessment programme	A pragmatic randomised controlled trial and economic evaluation of family therapy vs. treatment as usual for young people seen after second or subsequent episodes of self-harm: the Self-Harm Intervention - Family Therapy (SHIFT) trial
2022	NIHR Health Technology Assessment programme	Plasma exchange and glucocorticoids to delay death or end-stage renal disease in anti-neutrophil cytoplasm antibody-associated vasculitis: PEXIVAS non-inferiority factorial RCT
2022	NIHR Health Technology Assessment programme	Improving the prediction of metastatic disease in primary colorectal cancer: Prospective multicentre evaluation of a prognostic model of conventional predictive variables and novel variables derived from perfusion computed tomography (Perfusion CT)
2022	NIHR Health Technology Assessment programme	Uterine artery embolisation versus myomectomy for premenopausal women with uterine fibroids wishing to avoid hysterectomy: the FEMME RCT
2022	NIHR Health Technology Assessment programme	Telaprevir for the treatment of genotype 1 chronic hepatitis C
2022	NIHR Health Technology Assessment programme	Gastric bypass, adjustable gastric banding or sleeve gastrectomy surgery to treat severe and complex obesity: a multi-centre randomised controlled trial (The By-Band-Sleeve Study)
2022	NIHR Health Technology Assessment programme	The PRmotion Of Physical activity through structured Education with differing Levels of ongoing Support for those with prediabetes (PROPELS): randomised controlled trial in a diverse multi-ethnic community
2022	NIHR Health Technology Assessment programme	Dynamic contrast-enhanced CT compared with positron emission tomography CT to characterise solitary pulmonary nodules: the SPUtNIk diagnostic accuracy study and economic modelling
2022	NIHR Health Technology Assessment programme	Helicobacter pylori eradication for primary prevention of peptic ulcer bleeding in older patients prescribed aspirin in primary care (HEAT): a randomised, double-blind, placebo-controlled trial
2022	NIHR Health Technology Assessment programme	Mammographic surveillance in breast cancer patients aged 50 years or older
2022	NIHR Health Technology Assessment programme	REVascularisation of Ischaemic VEntricular Dysfunction (REVIVED): a randomised comparison of percutaneous coronary intervention (with optimal medical therapy) vs. optimal medical therapy alone for heart failure secondary to coronary disease
2022	NIHR Health Technology Assessment programme	Benefits of aldosterone receptor antagonism in chronic kidney disease (BARACK D) trial-a multi-centre, prospective, randomised, open, blinded end-point, 36-month study of 2,616 patients within primary care with stage 3b chronic kidney disease to compare the efficacy of spironolactone 25 mg once daily in addition to routine care on mortality and cardiovascular outcomes versus routine care alone: study protocol for a randomized controlled trial
2022	NIHR Health Technology Assessment programme	Shockwave lithotripsy compared with ureteroscopic stone treatment for adults with ureteric stones: the TISU non-inferiority RCT
2022	NIHR Health Technology Assessment programme	TARGIT-B: An international randomised controlled trial to compare targeted intra-operative radiotherapy boost with conventional external beam radiotherapy boost after lumpectomy for breast cancer in women with a high risk of local recurrence
2022	NIHR Health Technology Assessment programme	Synthetic sling or artificial urinary sphincter for men with urodynamic stress incontinence after prostate surgery: the MASTER non-inferiority RCT
2022	NIHR Health Technology Assessment programme	The United Kingdom Transcatheter Aortic Valve Implantation (UK TAVI) Trial
2022	NIHR Health Technology Assessment programme	Daily low-dose prednisolone to prevent relapse of steroid-sensitive nephrotic syndrome in children with an upper respiratory tract infection: PREDNOS2 RCT
2022	NIHR Health Technology Assessment programme	Endovascular stent grafting and open surgical replacement for chronic thoracic aortic aneurysms: a systematic review and prospective cohort study
2022	NIHR Health Technology Assessment programme	Planned early delivery or expectant management for late preterm pre-eclampsia (PHOENIX): a randomised controlled trial
2022	NIHR Health Technology Assessment programme	Outcome after selective early closure of ductus arteriosus in extremely preterm babies (Baby-OSCAR trial)
2022	NIHR Health Technology Assessment programme	Exercise to prevent shoulder problems after breast cancer surgery: the PROSPER RCT
2022	NIHR Health Technology Assessment programme	The Best Services Trial (BeST?): Effectiveness and cost-effectiveness of the New Orleans Intervention Model for Infant Mental Health
2022	NIHR Health Technology Assessment programme	A rapid intrapartum test for group B Streptococcus to reduce antibiotic usage in mothers with risk factors: the GBS2 cluster RCT
2022	NIHR Health Technology Assessment programme	Assessing the efficacy and safety of methotrexate vs ciclosporin in the treatment of severe atopic eczema in children: the TREatment of severe Atopic eczema in children Taskforce (TREAT) randomised controlled trial
2022	NIHR Health Technology Assessment programme	A proportionate, universal parenting programme to enhance social-emotional well-being in infants and toddlers in England: the E-SEE Steps RCT
2022	NIHR Health Technology Assessment programme	Early computed tomography coronary angiography in adults presenting with suspected acute coronary syndrome: the RAPID-CTCA RCT
2022	NIHR Health Technology Assessment programme	Monoclonal antibody BTT1023 targeting vascular adhesion protein 1 for treating primary sclerosing cholangitis: BUTEO single-arm Phase II trial
2022	NIHR Health Technology Assessment programme	Impact of video-assisted thoracoscopic lobectomy versus open lobectomy for lung cancer on recovery assessed using self-reported physical function: VIOLET RCT
2022	NIHR Health Technology Assessment programme	Non-invasive testing for early detection of neovascular macular degeneration in unaffected second eyes of older adults: EDNA diagnostic accuracy study
2022	NIHR Health Technology Assessment programme	StereoTactic radiotherapy for wet Age-Related macular degeneration (STAR): A randomised, double-masked, sham- controlled, clinical trial comparing low-voltage X-ray irradiation with as needed ranibizumab, to as needed ranibizumab monotherapy
2022	NIHR Health Technology Assessment programme	Development, implementation and evaluation of an early warning system improvement programme for children in hospital: the PUMA mixed-methods study
2022	NIHR Health Technology Assessment programme	Supraglottic airway device versus tracheal intubation in the initial airway management of out-of-hospital cardiac arrest: the AIRWAYS-2 cluster RCT
2022	NIHR Health Technology Assessment programme	Transfer of thawed frozen embryo versus fresh embryo to improve the healthy baby rate in women undergoing IVF: the E-Freeze RCT
2022	NIHR Health Technology Assessment programme	RCT of clinical and cost-effectiveness of drug coated balloons, drug eluting stents and balloon angioplasty with bail-out bare metal stent revascularisation strategies for severe limb ischaemia due to femoro-popliteal disease: BASIL-3 (Balloon vs Stenting in Severe Ischaemia of the Leg)
2022	NIHR Public Health Research (PHR) programme	A group-based exercise and behavioural maintenance intervention for adults over 65 years with mobility limitations: the REACT RCT
2022	NIHR Health Services and Delivery Research programme	Equal access to hospital care for children with learning disabilities and their families: a mixed-methods study
2022	NIHR Health Technology Assessment programme	Endometrial scratch to increase live birth rates in women undergoing first-time in vitro fertilisation: RCT and systematic review
2022	NIHR Health Services and Delivery Research programme	Complex speech-language therapy interventions for stroke-related aphasia: the RELEASE study incorporating a systematic review and individual participant data network meta-analysis
2022	NIHR Health Technology Assessment programme	Methenamine hippurate compared with antibiotic prophylaxis to prevent recurrent urinary tract infections in women: the ALTAR non-inferiority RCT
2022	NIHR Health Technology Assessment programme	Digital smartphone intervention to recognise and manage early warning signs in schizophrenia to prevent relapse: the EMPOWER feasibility cluster RCT
2022	NIHR Health Technology Assessment programme	A multidomain decision support tool to prevent falls in older people: the FinCH cluster RCT
2022	NIHR Health Technology Assessment programme	One-session treatment compared with multisession CBT in children aged 7–16 years with specific phobias: the ASPECT non-inferiority RCT
2022	NIHR Health Technology Assessment programme	Optimal pharmacotherapy pathway in adults with diabetic peripheral neuropathic pain: the OPTION-DM RCT
2022	NIHR Health Technology Assessment programme	Moulded cast compared with K-wire fixation after manipulation of an acute dorsally displaced distal radius fracture: the DRAFFT 2 RCT
2022	NIHR Health Technology Assessment programme	Infective endocarditis following invasive dental procedures: IDEA case-crossover study
2022	NIHR Health Technology Assessment programme	Sensory integration therapy for children with autism and sensory processing difficulties: the SenITA RCT
2022	Scientific Advice Unit, avalia-t; The Galician Health Knowledge Agency (ACIS)	[Home-based oral nutritional supplements in cancer patients who require modification of the usual ordinary diet due to mucositis]
2022	Scientific Advice Unit, avalia-t; The Galician Health Knowledge Agency (ACIS)	[Home-based oral nutritional supplements in cancer patients with moderate-severe malnutrition undergoing active treatment]
2022	Health Technology Wales (HTW)	Virtual reality interventions for the management of pain associated with medical procedures
2022	Ontario Health	Molecular testing for thyroid nodules with atypical cells of indeterminate significance
2022	Scientific Advice Unit, avalia-t; The Galician Health Knowledge Agency (ACIS)	[Home enteral nutrition in older patients with severe protein-energy malnutrition after hip fracture]
2022	Scientific Advice Unit, avalia-t; The Galician Health Knowledge Agency (ACIS)	[Bronchial thermoplasty in severe asthma]
2022	Scientific Advice Unit, avalia-t; The Galician Health Knowledge Agency (ACIS)	[Radiofrequency ablation for treatment of symptomatic uterine myomas]
2022	Swedish Agency for Health Technology Assessment and Assessment of Social Services (SBU)	[Occupational exposure and upper extremity pain]
2022	Swedish Agency for Health Technology Assessment and Assessment of Social Services (SBU)	[Food in diabetes]
2022	Swedish Agency for Health Technology Assessment and Assessment of Social Services (SBU)	[Wheelchairs and wheelchair accessories]
2022	Swedish Agency for Health Technology Assessment and Assessment of Social Services (SBU)	[Treatment of women with diastasis recti]
2022	Swedish Agency for Health Technology Assessment and Assessment of Social Services (SBU)	[Effects of return-to-work interventions for persons on long-term sick-leave due to mood-, anxiety- or adjustment disorders]
2022	Swedish Agency for Health Technology Assessment and Assessment of Social Services (SBU)	[Treatments for extreme nausea and vomiting in pregnancy (hyperemesis gravidarum)]
2022	Swiss Federal Office of Public Health (FOPH)	Denosumab (Prolia®) for the treatment of osteoporosis
2022	Swiss Federal Office of Public Health (FOPH)	Trimonthly vs. monthly use of bone-targeted agents in patients with bone metastases and multiple myeloma
2022	Swiss Federal Office of Public Health (FOPH)	Sedative-hypnotic drugs for the treatment of primary chronic insomnia disorder
2022	Swiss Federal Office of Public Health (FOPH)	Levothyroxine for patients diagnosed with subclinical hypothyroidism
2022	Norwegian Institute of Public Health (NIPH)	Transperineal compared with transrectal biopsy on suspected prostate cancer: a health technology assessment
2022	Swedish Agency for Health Technology Assessment and Assessment of Social Services (SBU)	[Post COVID-19 – effective treatment and rehabilitation]
2022	Swedish Agency for Health Technology Assessment and Assessment of Social Services (SBU)	[Promoting mental well-being in children and adolescents]
2022	Swiss Federal Office of Public Health (FOPH)	Medicines for dementia due to Alzheimer's disease and Parkinson's disease
2022	Swiss Federal Office of Public Health (FOPH)	Thyroid function tests for the diagnosis of suspected primary or secondary thyroid dysfunction
2022	Norwegian Institute of Public Health (NIPH)	Tests for the detection of NTRK gene fusions in patients with locally advanced or metastatic solid tumours
2022	NIHR Health Technology Assessment programme	Modelling approaches for histology-independent cancer drugs to inform NICE appraisals: a systematic review and decision-framework
2022	Canadian Agency for Drugs and Technologies in Health (CADTH)	Rituximab for the treatment of primary membranous nephropathy
2022	Canadian Agency for Drugs and Technologies in Health (CADTH)	Peer support programs for youth mental health
2022	Canadian Agency for Drugs and Technologies in Health (CADTH)	Internet-delivered cognitive behavioural therapy in the treatment of chronic non-cancer pain
2022	Canadian Agency for Drugs and Technologies in Health (CADTH)	Intraocular lens implantation for infants with aphakia: a systematic review of clinical effectiveness and cost-effectiveness
2022	Institut national d'excellence en sante et en services sociaux (INESSS)	[State of knowledge: integration of real-world data and evidence into assessments to support decision-making in the pharmaceutical sector]
2022	Penn Medicine Center for Evidence-based Practice (CEP)	Workplace violence in healthcare settings
2022	Institut national d'excellence en sante et en services sociaux (INESSS)	[Report: evaluation of Synvisc and Synvisc One for the management of knee osteoarthritis]
2022	NIHR Health Technology Assessment programme	Coenzyme Q10 to manage chronic heart failure with a reduced ejection fraction: a systematic review and economic evaluation
2022	NIHR Health Technology Assessment programme	Shock-absorbing flooring for fall-related injury prevention in older adults and staff in hospitals and care homes: the SAFEST systematic review
2022	NIHR Health Technology Assessment programme	Endovascular stent grafting and open surgical replacement for chronic thoracic aortic aneurysms: a systematic review and prospective cohort study
2022	Scottish Health Technologies Group (SHTG)	Closed loop systems and the artificial pancreas for type I diabetes mellitus (T1DM)
2022	Institut national d'excellence en sante et en services sociaux (INESSS)	[State of knowledge: next-generation sequencing (NGS) panels for muscle disease]
2022	Institut national d'excellence en sante et en services sociaux (INESSS)	[Report: detection of Chlamydia trachomatis, Neisseria gonorrhoeae and Trichomonas vaginalis by NAAT]
2022	Centre intégré universitaire de santé et de services sociaux de la Capitale-Nationale (CIUSSS)	[The use of social media and electronic communication in the delivery of youth protection services to young people in difficulty and their families]
2022	NIHR Health Technology Assessment programme	Biomarkers for assessing acute kidney injury for people who are being considered for admission to critical care: a systematic review and cost-effectiveness analysis
2022	NIHR Health Technology Assessment programme	Endometrial scratch to increase live birth rates in women undergoing first-time in vitro fertilisation: RCT and systematic review
2022	The Federal Joint Committee (G-BA)	[Pharmaceutical Directive/Annex XII: Satralizumab (neuromyelitis optica spectrum disorders, anti-aquaporin-4IgG seropositive, ≥ 12 years)]
2022	Basque Office for Health Technology Assessment (OSTEBA)	[Autism spectrum disorder: scientific evidence on its detection, diagnosis and treatment]
2022	Basque Office for Health Technology Assessment (OSTEBA)	[Image-guided spinal fusion technology]
2022	Basque Office for Health Technology Assessment (OSTEBA)	[Temporary percutaneous circulatory support devices for the treatment and prevention of cardiogenic shock: analysis of efficacy, effectiveness and safety]
2022	Institut national d'excellence en sante et en services sociaux (INESSS)	[State of knowledge: amyotrophic lateral sclerosis with or without frontotemporal dementia NGS panel]
2022	Institut national d'excellence en sante et en services sociaux (INESSS)	[Guidelines and standards: optimal use of immunoglobulin in solid organ transplantation]
2022	Swedish Agency for Health Technology Assessment and Assessment of Social Services (SBU)	[Systematic review of health care interventions in the context of return to work for persons being at risk for long-term sick leave]
2022	Institut national d'excellence en sante et en services sociaux (INESSS)	[State of knowledge: biologic dose escalation - gastroenterology, rheumatology and dermatology]
2022	Institut national d'excellence en sante et en services sociaux (INESSS)	[Report: evaluation of Afstyla™ (rFVIII) – type A hemophilia]
2022	Penn Medicine Center for Evidence-based Practice (CEP)	Restrictive red blood cell (RBC) transfusion thresholds: update