[Home-based oral nutritional supplements in cancer patients who require modification of the usual ordinary diet due to mucositis]

Noguerira-Uzal N, Paz-Valiñas L, Faraldo-Vallés MJ, Mejuto-Martí T
Record ID 32018000238
English, Spanish
Original Title: Nutrición enteral domiciliaria en pacientes oncológicos que requieren modificación de la dieta ordinaria habitual por mucositis
Authors' objectives: To assess the existing evidence on the benefit of HEN treatment on nutritional status in cancer patients with OM.
Authors' results and conclusions: RESULTS Of the 1149 publications retrieved through the literature search, 63 (52 articles and 11 ongoing studies) were selected for full text reading. However, it was not possible to include any studies as no RCTs were found that met the inclusion/exclusion criteria indicated in the methodology for this report. Among the different reasons, the study population did not meet the criteria of the target population, defined as those with OM at the start of the study, or because the nutritional intervention did not meet the definition of ONS as a part of HEN. CONCLUSIONS - No clinical trials have been found that study the usefulness of HEN in the management of oncology patients with OM. - Cancer patients with, or at risk of developing, OM should be supported by appropriate nutritional counselling aimed at dietary and hygienic measures to facilitate the swallowing of food for as long as possible.
Authors' methods: A systematic review of the scientific literature was conducted in the main databases (Cochrane Library, INAHTA, Medline, Embase, ISI Web of Knowkedge, GIN, NICE, SIGN and ClinicalTrials.gov) updated in August 2020 and with no time limit. Explicit pre-defined inclusion/exclusion criteria based on the PICOD research question (patients, intervention, comparison, outcomes and study design) were followed. Study selection was carried out by two independent reviewers and the quality of evidence of the included studies was assessed using the GRADE system. The risk of bias assessment was carried out using different scales and tools depending on the study design: the AMSTAR-2 (A MeaSurement Tool to Assess Reviews) for systematic reviews, the Cochrane Risk of Bias (RoB) 2.0 for randomised controlled trials (RCTs) and the AGREE II (Appraisal of Guidelines for Research and Evaluation) for the clinical practice guidelines (CPG).
Project Status: Completed
Year Published: 2022
English language abstract: An English language summary is available
Publication Type: Full HTA
Country: Spain
MeSH Terms
  • Mucositis
  • Antineoplastic Agents
  • Neoplasms
  • Enteral Nutrition
  • Dietary Supplements
  • Mucositis
  • enteral nutrition
Organisation Name: Scientific Advice Unit, avalia-t; The Galician Health Knowledge Agency (ACIS)
Contact Address: Conselleria de Sanidade, Xunta de Galicia, San Lazaro s/n 15781 Santiago de Compostela, Spain. Tel: 34 981 541831; Fax: 34 981 542854;
Contact Name: avalia-t@sergas.es
Contact Email: avalia-t@sergas.es
Copyright: Scientific Advice Unit, avalia-t; The Galician Health Knowledge Agency (ACIS)
This is a bibliographic record of a published health technology assessment from a member of INAHTA or other HTA producer. No evaluation of the quality of this assessment has been made for the HTA database.