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Welcome to the international HTA database

CSV RIS
Showing [24069 Records] Selected Records [0 Hits] [Clear]
Year Source Title
2011     NIHR Health Technology Assessment programme Ranibizumab for the treatment of diabetic macular oedema
2014     NIHR Health Technology Assessment programme The clinical effectiveness, cost-effectiveness and acceptability of community-based interventions aimed at improving or maintaining quality of life in children of parents with serious mental illness: a systematic review
2016     NIHR Health Technology Assessment programme The Protease Inhibitor Monotherapy Versus Ongoing Triple Therapy (PIVOT) trial: a randomised controlled trial of a protease inhibitor monotherapy strategy for long-term management of human immunodeficiency virus infection
2005     NIHR Health Technology Assessment programme The British Rheumatoid Outcome Study Group (BROSG) randomised controlled trial to compare the effectiveness and cost-effectiveness of aggressive versus symptomatic therapy in established rheumatoid arthritis
2004     NIHR Health Technology Assessment programme Routine examination of the newborn: the EMREN study. Evaluation of an extension of the midwife role including a randomised controlled trial of appropriately trained midwives and paediatric senior house officers
2007     NIHR Health Technology Assessment programme A systematic review of rapid diagnostic tests for the detection of tuberculosis infection
2012     NIHR Health Technology Assessment programme The effectiveness and cost-effectiveness of enzyme and substrate replacement therapies: a longitudinal cohort study of people with lysosomal storage disorders
2012     NIHR Health Technology Assessment programme Dasatinib, nilotinib and standard-dose imatinib for the first-line treatment of chronic myeloid leukaemia: systematic reviews and economic analyses
2015     NIHR Health Technology Assessment programme Double-blind randomised controlled trial of percutaneous tibial nerve stimulation versus sham electrical stimulation in the treatment of faecal incontinence: CONtrol of Faecal Incontinence using Distal NeuromodulaTion (the CONFIDeNT trial)
2022     NIHR Health Technology Assessment programme Methenamine hippurate compared with antibiotic prophylaxis to prevent recurrent urinary tract infections in women: the ALTAR non-inferiority RCT
2024     NIHR Health Technology Assessment programme Cervical ripening at home or in hospital during induction of labour: the CHOICE prospective cohort study, process evaluation and economic analysis
2004     NIHR Health Technology Assessment programme Towards efficient guidelines: 1. When to develop guidelines- systematic review
2006     NIHR Health Technology Assessment programme Infrastructure for guideline development
2013     NIHR Health Technology Assessment programme Gene expression profiling and expanded immunohistochemistry tests to guide the use of adjuvant chemotherapy in breast cancer management: a systematic review and cost-effectiveness analysis
2024     NIHR Health Technology Assessment programme The effect of two speech and language approaches on speech problems in people with Parkinson’s disease: the PD COMM RCT
2014     NIHR Health Technology Assessment programme A randomised controlled trial of the clinical effectiveness and cost-effectiveness of different knee prostheses: the Knee Arthroplasty Trial (KAT)
2013     NIHR Health Technology Assessment programme A high-dose preparation of lactobacilli and bifidobacteria in the prevention of antibiotic-associated and Clostridium difficile diarrhoea in older people admitted to hospital: a multicentre, randomised, double-blind, placebo-controlled, parallel arm trial (PLACIDE)
2012     NIHR Health Technology Assessment programme Abatacept for the treatment of rheumatoid arthritis after the failure of conventional disease-modifying antirheumatic drugs
2021     NIHR Health Technology Assessment programme Tranexamic acid to reduce head injury death in people with traumatic brain injury: the CRASH-3 international RCT
2021     NIHR Health Technology Assessment programme Smoking cessation medicines and e-cigarettes: a systematic review, network meta-analysis and cost-effectiveness analysis
2007     NIHR Health Technology Assessment programme A randomised controlled trial examining the longer-term outcomes of standard versus new antiepileptic drugs The SANAD trial
2001     NIHR Health Technology Assessment programme The clinical effectiveness and cost-effectiveness of riluzole for motor neurone disease: a rapid and systematic review
2014     NIHR Health Technology Assessment programme A clinical and economic evaluation of Control of Hyperglycaemia in Paediatric intensive care: the CHiP randomised controlled trial
2010     NIHR Health Technology Assessment programme Systematic review of the links between human resource management practices and performance
2017     NIHR Health Technology Assessment programme Debt Counselling for Depression in Primary Care: an adaptive randomised controlled pilot trial (DeCoDer study)
2020     NIHR Health Technology Assessment programme Surgical treatments compared with early structured physiotherapy in secondary care for adults with primary frozen shoulder: the UK FROST three-arm RCT
2016     NIHR Health Technology Assessment programme OPTIMA prelim: a randomised feasibility study of personalised care in the treatment of women with early breast cancer
2022     NIHR Health Technology Assessment programme Dynamic contrast-enhanced CT compared with positron emission tomography CT to characterise solitary pulmonary nodules: the SPUtNIk diagnostic accuracy study and economic modelling
2024     NIHR Health Technology Assessment programme Energetic activity for depression in young people aged 13–17 years: the READY feasibility RCT
2004     NIHR Health Technology Assessment programme Diagnosis of endometrial abnormality: comparison of outpatient procedures within cohorts defined by age and menopausal status
2002     NIHR Health Technology Assessment programme Fludarabine as second-line therapy for B cell chronic lymphocytic leukaemia: a technology assessment
2013     NIHR Health Technology Assessment programme Improving the economic value of photographic screening for optical coherence tomography-detectable macular oedema: a prospective, multicentre, UK study
2013     NIHR Health Technology Assessment programme Systematic review, meta-analysis and economic modelling of diagnostic strategies for suspected acute coronary syndrome
2014     NIHR Health Technology Assessment programme Imatinib for the adjuvant treatment of gastrointestinal stromal tumours
2019     NIHR Health Technology Assessment programme Platelet Rich Plasma (PRP) in Achilles Tendon Rupture (ATR) healing
2016     NIHR Health Technology Assessment programme Improving outcomes for people in mental health crisis: a rapid synthesis of the evidence for available models of care
2017     NIHR Health Technology Assessment programme A Very Early Rehabilitation Trial after stroke (AVERT): a Phase III, multicentre, randomised controlled trial
2025     NIHR Health Technology Assessment programme A personalised health intervention to maintain independence in older people with mild frailty: a process evaluation within the HomeHealth RCT
2001     NIHR Health Technology Assessment programme Systematic reviews of (i) comparative studies of depot neuroleptic drugs, and (ii) studies of oral vs depot neuroleptic agents for patients with schizophrenia: clinical, social and economic outcomes- systematic review
2002     NIHR Health Technology Assessment programme Rituximab as third-line treatment for refractory or recurrent Stage III or IV follicular non-Hodgkin's lymphoma: a systematic review and economic evaluation
2013     NIHR Health Technology Assessment programme Development and validation of a risk model for identification of non-neutropenic, critically ill adult patients at high risk of invasive candida infection: the Fungal Infection Risk Evaluation (FIRE) study
2019     NIHR Health Technology Assessment programme Models Of Reablement Evaluation: a mixed methods evaluation of a complex intervention (The MORE project)
2017     NIHR Health Technology Assessment programme Provision of information about newborn screening antenatally: a sequential exploratory mixed-methods project
2024     NIHR Health Technology Assessment programme Emollient application from birth to prevent eczema in high-risk children: the BEEP RCT
2025     NIHR Health Technology Assessment programme Anti-VEGF drugs compared with laser photocoagulation for the treatment of proliferative diabetic retinopathy: a systematic review and individual participant data meta-analysis
2010     NIHR Health Technology Assessment programme Multicentre randomised controlled trial of the clinical and cost-effectiveness of a bypass-surgery-first versus a balloon-angioplasty-first revascularisation strategy for severe limb ischaemia due to infrainguinal disease. The Bypass versus Angioplasty in Severe Ischaemia of the Leg (BASIL) trial
2002     NIHR Health Technology Assessment programme The clinical effectiveness and cost-effectiveness of sibutramine in the management of obesity: a technology assessment
2010     NIHR Health Technology Assessment programme INTERVAL Dental recalls trial (Investigation of NICE Technologies for Enabling Risk-Variable-Adjusted-Length Dental Recalls Trial) - a feasibility study and follow on
2020     NIHR Health Technology Assessment programme A multicentre randomised trial to establish the effect(s) of routine administration of fluoxetine in patients with a recent stroke (FOCUS)
2017     NIHR Health Technology Assessment programme Certolizumab pegol and secukinumab for treating active psoriatic arthritis following inadequate response to disease-modifying antirheumatic drugs: a systematic review and economic evaluation
2024     NIHR Health Technology Assessment programme Devices for remote continuous monitoring of people with Parkinson’s disease: a systematic review and cost-effectiveness analysis
2006     NIHR Health Technology Assessment programme Evaluation of molecular techniques in prediction and diagnosis of CMV disease in immunocompromised individuals- primary research
2002     NIHR Health Technology Assessment programme The cost-effectiveness of magnetic resonance angiography for carotid artery stenosis and peripheral vascular disease: a systematic review
2006     NIHR Health Technology Assessment programme Adefovir dipivoxil and pegylated interferon alfa-2a for the treatment of chronic hepatitis B: a systematic review and economic evaluation
2007     NIHR Health Technology Assessment programme Exercise Evaluation Randomised Trial (EXERT): a randomised trial comparing GP referral for leisure centre-based exercise, community-based walking and advice only
2015     NIHR Health Technology Assessment programme Clinical and cost-effectiveness of foam sclerotherapy, endovenous laser ablation and surgery for varicose veins: results from the CLASS trial
2020     NIHR Health Technology Assessment programme Effectiveness of progesterone to prevent miscarriage in women with early pregnancy bleeding: a randomised placebo-controlled trial (PRISM Trial: PRogesterone In Spontaneous Miscarriage Trial)
2017     NIHR Health Technology Assessment programme International multicentre randomised controlled trial of improvisational music therapy for children with autism spectrum disorder: TIME-A study
2024     NIHR Health Technology Assessment programme A cloud-based medical device for predicting cardiac risk in suspected coronary artery disease: a rapid review and conceptual economic model
2025     NIHR Health Technology Assessment programme Stopping anticoagulation for isolated or incidental subsegmental pulmonary embolism: the challenges and lessons from the STOPAPE RCT
1999     NIHR Health Technology Assessment programme Endovascular aortic aneurysm repair (EVAR) trials
2002     NIHR Health Technology Assessment programme Promoting physical activity in South Asian Muslim women through 'exercise on prescription'
2006     NIHR Health Technology Assessment programme A review of the evidence on the effects and costs of implantable cardioverter defibrillator therapy in different patient groups, and modelling of cost-effectiveness and cost-utility for these groups in a UK context
2016     NIHR Health Technology Assessment programme Alpha-2 agonists for sedation of mechanically ventilated adults in intensive care units: a systematic review
2016     NIHR Health Technology Assessment programme Sepsis: the LightCycler SeptiFast Test MGRADE®, SepsiTest™ and IRIDICA BAC BSI assay for rapidly identifying bloodstream bacteria and fungi – a systematic review and economic evaluation
2021     NIHR Health Technology Assessment programme Improving the Wellbeing of people with Opioid Treated CHronic pain; I-WOTCH
2024     NIHR Health Technology Assessment programme Home-monitoring for neovascular age-related macular degeneration in older adults within the UK: the MONARCH diagnostic accuracy study
2025     NIHR Health Technology Assessment programme Lessons from the PROTECT-CH COVID-19 platform trial in care homes
2006     NIHR Health Technology Assessment programme Cost utility of the latest antipsychotics in severe schizophrenia (CUtLASS): a multicenter, randomized controlled trial
2002     NIHR Health Technology Assessment programme A review of the natural history and epidemiology of multiple sclerosis: implications for resource allocation and health economic models
2014     NIHR Health Technology Assessment programme Optimal strategies for identifying kidney disease in diabetes: properties of screening tests, progression of renal dysfunction and impact of treatment -systematic review and modelling of progression and cost-effectiveness
2005     NIHR Health Technology Assessment programme A systematic review and economic evaluation of alendronate, etidronate, risedronate, raloxifene and teriparatide for the prevention and treatment of postmenopausal osteoporosis
2024     NIHR Health Technology Assessment programme Reducing self-harm in adolescents: the RISA-IPD individual patient data meta-analysis and systematic review
2008     NIHR Health Technology Assessment programme A prospective randomized comparison of minor surgery in primary and secondary care
2007     NIHR Health Technology Assessment programme Cost-effectiveness of functional cardiac testing in the diagnosis and management of coronary artery disease: a randomised controlled trial. The CECaT trial
2015     NIHR Health Technology Assessment programme Smoking Cessation Intervention for severe Mental Ill Health Trial (SCIMITAR): a pilot randomised control trial of the clinical effectiveness and cost-effectiveness of a bespoke smoking cessation service
2015     NIHR Health Technology Assessment programme The clinical effectiveness and cost-effectiveness of open mesh repairs in adults presenting with a clinically diagnosed primary unilateral inguinal hernia who are operated in an elective setting: systematic review and economic evaluation
2017     NIHR Health Technology Assessment programme Cognitive behavioural therapy and short-term psychoanalytic psychotherapy versus brief psychosocial intervention in adolescents with unipolar major depression (IMPACT): a multicentre, pragmatic, observer-blind, randomised controlled trial
2025     NIHR Health Technology Assessment programme Supporting self-management with an internet intervention for low back pain in primary care: a RCT (SupportBack 2)
2005     NIHR Health Technology Assessment programme Wessex Epidural Steroids Trial (WEST), primary research
2007     NIHR Health Technology Assessment programme Evaluation of diagnostic tests when there is no gold standard. A review of methods
2017     NIHR Health Technology Assessment programme A novel peer-support intervention using motivational interviewing for breastfeeding maintenance:a UK feasibility study
2017     NIHR Health Technology Assessment programme Prehospital randomised assessment of a mechanical compression device in out-of-hospital cardiac arrest (PARAMEDIC): a pragmatic, cluster randomised trial and economic evaluation
2025     NIHR Health Technology Assessment programme Evaluation of prognostic models to improve prediction of metastasis in patients following potentially curative treatment for primary colorectal cancer: the PROSPECT trial
2003     NIHR Health Technology Assessment programme "CLIP" Central Line Insertion Project, primary research
2007     NIHR Health Technology Assessment programme Systematic reviews of the clinical effectiveness and cost-effectiveness of proton pump inhibitors in acute upper gastrointestinal bleeding
2012     NIHR Health Technology Assessment programme A pilot randomised controlled trial in intensive care patients comparing 7 days' treatment with empirical antibiotics with 2 days' treatment for hospital-acquired infection of unknown origin
2022     NIHR Health Technology Assessment programme Endovascular stent grafting and open surgical replacement for chronic thoracic aortic aneurysms: a systematic review and prospective cohort study
2014     NIHR Health Technology Assessment programme Systematic review and modelling of the cost-effectiveness of cardiac magnetic resonance imaging compared with current existing testing pathways in ischaemic cardiomyopathy
2021     NIHR Health Technology Assessment programme A Phase II randomised clinical trial of conditioning cyclophosphamide and chemoembolisation with or without vaccination with dendritic cells pulsed with HepG2 lysate ex vivo in patients with Hepatocellular Carcinoma: IMMUNOTACE
2021     NIHR Health Technology Assessment programme The cystic fibrosis (CF) anti-staphylococcal antibiotic prophylaxis trial (CF START); a randomised registry trial to assess the safety and efficacy of flucloxacillin as a longterm prophylaxis agent for infants with CF
2017     NIHR Health Technology Assessment programme Pre-conception care for women with type 1 or type 2 diabetes: a mixed methods study exploring uptake of pre-conception care
2022     NIHR Health Technology Assessment programme Pre-hospital and emergency department treatment of convulsive status epilepticus in adults: an evidence synthesis
2010     NIHR Health Technology Assessment programme A randomised controlled multicentre trial of treatments for adolescent anorexia nervosa including assessment of cost-effectiveness and patient acceptability - the TOuCAN trial
2014     NIHR Health Technology Assessment programme AMIPROM - A randomised controlled trial of amnioinfusion versus expectant management in very early preterm premature rupture of membranes
2012     NIHR Health Technology Assessment programme Abiraterone acetate for the treatment of metastatic, castrate-resistant prostate cancer following previous cytotoxic chemotherapy
2018     NIHR Health Technology Assessment programme A longitudinal national evaluation of Schwartz Centre Rounds: an intervention to enhance compassion in relationships between staff and patients through providing support for staff and promoting their wellbeing
2019     NIHR Health Technology Assessment programme The Effectiveness and cost-effectiveness of Surgical Treatments for womEn with stRess urinary incontinence: an evidence synthesis (ESTER)
2017     NIHR Health Technology Assessment programme Randomised controlled trial of silk therapeutic garments for the management of atopic eczema in children: the CLOTHES trial
2022     NIHR Health Technology Assessment programme A large randomised assessment of the relative cost-effectiveness of different classes of drugs for Parkinson's disease (PD MED)