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Welcome to the international HTA database

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Year Source Title
2022     NIHR Health Technology Assessment programme Unspecified living kidney donation in the UK: barriers to implementation and delivery
2022     NIHR Health Technology Assessment programme Prospective randomised marker-based trial to assess the clinical utility and safety of biomarker-guided immunosuppression withdrawal in liver transplantation (LiverTOL-Dx Trial)
2022     NIHR Health Technology Assessment programme Assessing the efficacy and safety of methotrexate vs ciclosporin in the treatment of severe atopic eczema in children: the TREatment of severe Atopic eczema in children Taskforce (TREAT) randomised controlled trial
2022     NIHR Health Technology Assessment programme Paclitaxel assisted balloon Angioplasty of Venous stenosis in haEmodialysis access: The PAVE Trial. A multicentre double-blind randomised controlled trial in haemodialysis patients with a stenosis in a native arteriovenous fistula
2022     NIHR Health Technology Assessment programme Accuracy of a rapid intrapartum test for maternal group B streptococcal colonisation and its potential to reduce antibiotic usage in mothers with risk factors (GBS2)
2022     NIHR Health Technology Assessment programme The Best Services Trial (BeST?): Effectiveness and cost-effectiveness of the New Orleans Intervention Model for Infant Mental Health
2022     NIHR Health Technology Assessment programme DexEnceph- Dexamethasone in Herpes Simplex Virus Encephalitis Randomised Controlled Trial and NonHSV Cohort Study
2022     NIHR Health Technology Assessment programme Evaluation of the Healthy Start Voucher Scheme in UK: a natural experiment using the Growing Up in Scotland record linkage study and the Infant Feeding Survey
2022     NIHR Health Technology Assessment programme Exercise to prevent shoulder conditions in patients undergoing breast cancer treatment. The PRevention Of Shoulder Problems Study (PROSPER)
2022     NIHR Health Technology Assessment programme Outcome after selective early closure of ductus arteriosus in extremely preterm babies (Baby-OSCAR trial)
2022     NIHR Health Technology Assessment programme Pre-eclampsia in Hospital: Early Induction or Expectant management (PHOENIX)
2022     NIHR Health Technology Assessment programme Effective Treatments for Thoracic Aortic Aneurysms (ETTAA study): a prospective cohort study
2022     NIHR Health Technology Assessment programme Treatment of Advanced Glaucoma Study (TAGS): a multicentre randomised controlled trial comparing primary medical treatment with primary trabeculectomy for people with newly diagnosed advanced glaucoma
2022     NIHR Health Technology Assessment programme POSNOC - POsitive Sentinel NOde: adjuvant therapy alone versus adjuvant therapy plus Clearance or axillary radiotherapy: A randomised controlled trial of axillary treatment in women with early stage breast cancer who have metastases in one or two sentinel nodes
2022     NIHR Health Technology Assessment programme PRE-EMPT: Preventing Recurrence of Endometriosis by Means of long acting Progestogen Therapy
2022     NIHR Health Technology Assessment programme Short course daily prednisolone therapy at the time of upper respiratory tract infection in children with relapsing steroid sensitive nephrotic syndrome; the PREDNOS 2 study
2022     NIHR Health Technology Assessment programme HALT-IT trial (Haemorrhage Alleviation with Tranexamic acid Intestinal System), a large randomised placebo controlled trial among patients with acute gastrointestinal haemorrhage of the effects of tranexamic acid on death and transfusion requirement
2022     NIHR Health Technology Assessment programme Health-Related Quality of Life in two treatment pathways for newly diagnosed open angle glaucoma and ocular hypertension: an unmasked, multi-centre, randomised controlled trial of initial selective laser trabeculoplasty versus conventional medical therapy
2022     NIHR Health Technology Assessment programme Accuracy of glomerular filtration rate (GFR) estimation using creatinine and cystatin C and albuminuria for monitoring disease progression in patients with stage 3 chronic kidney disease: a prospective longitudinal study in a multiethnic population
2022     NIHR Health Technology Assessment programme The United Kingdom Transcatheter Aortic Valve Implantation (UK TAVI) Trial
2022     NIHR Health Technology Assessment programme Male synthetic sling versus Artificial urinary Sphincter Trial for men with urodynamic stress incontinence after prostate surgery: Evaluation by Randomised controlled trial (MASTER)
2022     NIHR Health Technology Assessment programme TARGIT-B: An international randomised controlled trial to compare targeted intra-operative radiotherapy boost with conventional external beam radiotherapy boost after lumpectomy for breast cancer in women with a high risk of local recurrence
2022     NIHR Health Technology Assessment programme Therapeutic Interventions for Stones of the Ureter (TISU): a multicentre randomised controlled trial of extracorporeal shockwave lithotripsy, as first treatment option, compared with direct progression to ureteroscopic retrieval, for ureteric stones
2022     NIHR Health Technology Assessment programme Benefits of Aldosterone Receptor Antagonism in Chronic Kidney Disease (BARACK D) Trial
2022     NIHR Health Technology Assessment programme Allopurinol and cardiovascular outcomes in patients with ischaemic heart disease
2022     NIHR Health Technology Assessment programme REVascularisation of Ischaemic VEntricular Dysfunction (REVIVED): a randomised comparison of percutaneous coronary intervention (with optimal medical therapy) vs. optimal medical therapy alone for heart failure secondary to coronary disease
2022     NIHR Health Technology Assessment programme The START (STrAtegies for RelaTives) study: a pragmatic randomised controlled trial to determine the effectiveness of a manual based coping strategy programme in promoting the mental health of carers of people with dementia - cohort follow-up
2022     NIHR Health Technology Assessment programme Mammographic surveillance in breast cancer patients aged 50 years or older
2022     NIHR Health Technology Assessment programme Helicobacter eradication to prevent ulcer bleeding in aspirin users: a large simple randomised controlled trial (HEAT)
2022     NIHR Health Technology Assessment programme Accuracy and cost-effectiveness of dynamic contrast enhanced computed tomography in the characterisation of solitary pulmonary nodules
2022     NIHR Health Technology Assessment programme The PRmotion Of Physical activity through structured Education with differing Levels of ongoing Support for those with prediabetes (PROPELS): randomised controlled trial in a diverse multi-ethnic community
2022     NIHR Health Technology Assessment programme Gastric Bypass, adjustable gastric Banding or Sleeve gastrectomy surgery to treat severe and complex obesity: a multi-centre randomised controlled trial (The By-Band-Sleeve Study)
2022     NIHR Health Technology Assessment programme SurgiCal Obesity Treatment Study (SCOTS)
2022     NIHR Health Technology Assessment programme A pragmatic randomised controlled trial comparing the effectiveness and cost effectiveness of levetiracetam and zonisamide versus standard treatments for epilepsy: a comparison of Standard And New Antiepileptic Drugs (SANAD-II)
2022     NIHR Health Technology Assessment programme Telaprevir for the treatment of genotype 1 chronic hepatitis C
2022     NIHR Health Technology Assessment programme Fast-Forward: a randomised clinical trial testing a 1-week course of curative whole breast radiotherapy against a standard 3-week schedule in terms of local cancer control and late adverse effects in women with early breast cancer
2022     NIHR Health Technology Assessment programme A randomised, multi-stage phase II/III study of standard first-line therapy (sunitinib or pazopanib) comparing temporary cessation with allowing continuation, in the treatment of locally advanced and/or metastatic renal cancer (the STAR trial)
2022     NIHR Health Technology Assessment programme FEMME trial: Randomised trial of treating Fibroids with either Embolisation or MyoMectomy to measure the Effect on quality of life
2022     NIHR Health Technology Assessment programme Improving the prediction of metastatic disease in primary colorectal cancer: Prospective multicentre evaluation of a prognostic model of conventional predictive variables and novel variables derived from perfusion computed tomography (Perfusion CT)
2022     NIHR Health Technology Assessment programme Randomised control trial of surveillance and no surveillance for patients with Barrett's oesophagus - BOSS (Barrett's Oesophagus Surveillance Study)
2022     NIHR Health Technology Assessment programme Plasma exchange and glucocorticoids in anti-neutrophil cytoplasm antibody associated systemic vasculitis: a randomized controlled trial. PEXIVAS
2022     NIHR Health Technology Assessment programme A pragmatic randomised controlled trial and economic evaluation of family therapy vs. treatment as usual for young people seen after second or subsequent episodes of self-harm: the Self-Harm Intervention - Family Therapy (SHIFT) trial
2022     NIHR Health Technology Assessment programme Multicentre UK study of the acetylcholinesterase inhibitor donepezil in early dementia associated with Parkinson's disease (MUSTARDD-PD)
2022     NIHR Health Technology Assessment programme A randomised controlled trial of a protease inhibitor monotherapy versus continuing combination antiretroviral therapy for HIV-1 infected patients previously established on a dual nucleoside and non-nucleoside combination regimen
2022     Medical Services Advisory Committee (MSAC) Two testing options for determining eligibility for access to Pharmaceutical Benefits Schedule-subsidised aducanumab in patients with early stage Alzheimer disease
2022     Medical Services Advisory Committee (MSAC) Genetic testing for childhood hearing impairment
2022     NIHR Health Technology Assessment programme A large randomised assessment of the relative cost-effectiveness of different classes of drugs for Parkinson's disease (PD MED)
2021     Canary Health Service [Prenatal screening for toxoplasmosis]
2021     Canary Health Service [Scalp cooling devices for the prevention of chemotherapy-induced alopecia]
2021     Canary Health Service [Decisional flowchart for patient involvement in health technology assessments]
2021     Canary Health Service [Artificial pancreas with dual release of insulin and pramlintide for treatment of type 1 diabetes mellitus]
2021     Canary Health Service [Effectiveness, safety, and cost-effectiveness of devices for peripheral venous catheterization: needleless connectors, passive disinfection caps and prefilled saline syringes]
2021     Canary Health Service [Monitoring study: "The sensor glucose monitoring system (flash-type) for type 1 diabetes mellitus in childhood and adolescence]
2021     Canary Health Service [Real-time continuous glucose monitoring device for gestational diabetes]
2021     Australian Safety and Efficacy Register of New Interventional Procedures -Surgical (ASERNIP-S) National spending and uptake of mobile radiology services in aged care facilities: an opportunity to improve access remains
2021     Australian Safety and Efficacy Register of New Interventional Procedures -Surgical (ASERNIP-S) Delaying surgery for patients recovering from COVID-19. A rapid review comissioned by RACS
2021     Australian Safety and Efficacy Register of New Interventional Procedures -Surgical (ASERNIP-S) Telehealth in surgery: an umbrella review
2021     Australian Safety and Efficacy Register of New Interventional Procedures -Surgical (ASERNIP-S) Proposed delay for safe surgery after COVID-19
2021     Australian Safety and Efficacy Register of New Interventional Procedures -Surgical (ASERNIP-S) Influence of COVID-19 vaccines on surgical practice
2021     Australian Safety and Efficacy Register of New Interventional Procedures -Surgical (ASERNIP-S) Evidence, not eminence, for surgical management during COVID-19: a multifaceted systematic review and a model for rapid clinical change
2021     Australian Safety and Efficacy Register of New Interventional Procedures -Surgical (ASERNIP-S) COVID-19: a test of evidence-based surgery
2021     Australian Safety and Efficacy Register of New Interventional Procedures -Surgical (ASERNIP-S) In hospital survival after pancreatoduodenectomy is greater in high volume hospitals versus lower volume hospitals: a meta analysis
2021     Australian Safety and Efficacy Register of New Interventional Procedures -Surgical (ASERNIP-S) Global HTA: past, present, and future
2021     Australian Safety and Efficacy Register of New Interventional Procedures -Surgical (ASERNIP-S) Triphasic biomaterial for augmentation of the osteoporotic femoral neck
2021     Australian Safety and Efficacy Register of New Interventional Procedures -Surgical (ASERNIP-S) Corneal collagen crosslinking for the treatment of progressive keratoconus
2021     Australian Safety and Efficacy Register of New Interventional Procedures -Surgical (ASERNIP-S) Subacromial decompression as a primary/isolated intervention to treat subacromial pain
2021     Australian Safety and Efficacy Register of New Interventional Procedures -Surgical (ASERNIP-S) Denosumab (Prolia) for the treatment of osteoporosis
2021     Australian Safety and Efficacy Register of New Interventional Procedures -Surgical (ASERNIP-S) Ezetimibe-containing medicines for the treatment of hypercholesterolaemia and mixed/combined hyperlipidaemia
2021     Australian Safety and Efficacy Register of New Interventional Procedures -Surgical (ASERNIP-S) Long-term physiotherapy in patients after stroke, with multiple sclerosis, or with Parkinson's disease
2021     Australian Safety and Efficacy Register of New Interventional Procedures -Surgical (ASERNIP-S) Effectiveness and safety of vitamin B12 tests
2021     Australian Safety and Efficacy Register of New Interventional Procedures -Surgical (ASERNIP-S) Artificial intelligence in surgery and surgical education
2021     Australian Safety and Efficacy Register of New Interventional Procedures -Surgical (ASERNIP-S) Streamlining Medicare Benefits Schedule items for positron emission tomography (PET) project
2021     Australian Safety and Efficacy Register of New Interventional Procedures -Surgical (ASERNIP-S) Alpha-1 antitrypsin genotyping
2021     Australian Safety and Efficacy Register of New Interventional Procedures -Surgical (ASERNIP-S) Modification of the wording of minimally invasive glaucoma surgery (MIGS) existing item number to encompass the use of a microcatheter
2021     Australian Safety and Efficacy Register of New Interventional Procedures -Surgical (ASERNIP-S) Modification of the wording of minimally invasive glaucoma surgery (MIGS) existing item number to encompass the use of a microcatheter
2021     Australian Safety and Efficacy Register of New Interventional Procedures -Surgical (ASERNIP-S) Permanent acute coronary syndrome event detector (insertion, removal or replacement of) for monitoring of the heart's electrical activity
2021     Australian Safety and Efficacy Register of New Interventional Procedures -Surgical (ASERNIP-S) Endoscopic sleeve gastroplasty for the treatment of patients with Class I and II obesity who have failed first-line (lifestyle modification) and second-line (VLED/pharmacotherapy) treatments
2021     Australian Safety and Efficacy Register of New Interventional Procedures -Surgical (ASERNIP-S) Ventral rectopexy for the treatment of rectal prolapse and intussusception
2021     Canary Health Service [Telemedicine for the management of consultations, evaluations and therapeutic management in neurological diseases]
2021     Canary Health Service [Efficacy and safety of floral therapy]
2021     Canary Health Service [Foot reflexology]
2021     Institut fuer Qualitaet und Wirtschaftlichkeit im Gesundheitswesen (IQWiG) [Acalabrutinib (pretreated chronic lymphocytic leukaemia) - Second Addendum to Commission A20-105]
2021     NIHR Health Technology Assessment programme Feasibility of a RCT of techniques for managing an impacted fetal head during emergency caesarean section: the MIDAS scoping study
2021     Adelaide Health Technology Assessment (AHTA) Genetic testing for childhood hearing impairment
2021     Adelaide Health Technology Assessment (AHTA) Whole genome sequencing of antimicrobial-resistant pathogens
2021     Adelaide Health Technology Assessment (AHTA) Small gene panel testing for NSCLC
2021     Institute for Clinical Effectiveness and Health Policy (IECS) [Tafamidis for transthyretin amyloid cardiomyopathy]
2021     Institute for Clinical Effectiveness and Health Policy (IECS) [Intense-pulse-light therapy treatment for dry eye syndrome]
2021     Institute for Clinical Effectiveness and Health Policy (IECS) [Auditory integration therapy for autism spectrum disorders]
2021     Institute for Clinical Effectiveness and Health Policy (IECS) [Vosoritide in achondroplasia]
2021     Institute for Clinical Effectiveness and Health Policy (IECS) [Botulinum toxin in adult patients with overactive bladder]
2021     Institute for Clinical Effectiveness and Health Policy (IECS) [Edaravone in patients with amyotrophic lateral sclerosis]
2021     Institut fuer Qualitaet und Wirtschaftlichkeit im Gesundheitswesen (IQWiG) [Glecaprevir/pibrentasvir (chronic hepatitis C in children) - Benefit assessment according to §35a Social Code Book V]
2021     Belgian Health Care Knowledge Centre (KCE) Do innovative medicines against cancer always have a real added value?
2021     Malaysian Health Technology Assessment (MaHTAS) Versajet hydrosurgery system for wound debridement: an update
2021     Malaysian Health Technology Assessment (MaHTAS) Single dose rifampicin (SDR) as a prophylaxis for leprosy contacts
2021     Malaysian Health Technology Assessment (MaHTAS) 5-aminolevulinic acid (5-ALA) for brain tumour surgical procedure
2021     Malaysian Health Technology Assessment (MaHTAS) Rezūm therapy for management of benign prostatic hyperplasia
2021     Malaysian Health Technology Assessment (MaHTAS) Proton beam therapy for the treatment of cancer - an update
2021     Canadian Agency for Drugs and Technologies in Health (CADTH) Remote monitoring programs for cardiac conditions