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Year Source Title
2021 Medical Services Advisory Committee (MSAC) Six genetic tests for the diagnosis of inheritable cardiac conduction disorders
2021 NIHR Health Technology Assessment programme Fall prevention interventions in primary care to reduce fractures and falls in people aged 70 years and over: the PreFIT three-arm cluster RCT
2021 NIHR Health Technology Assessment programme Lamotrigine versus levetiracetam or zonisamide for focal epilepsy and valproate versus levetiracetam for generalised and unclassified epilepsy: two SANAD II non-inferiority RCTs
2021 German Agency for Health Technology Assessment at the German Institute for Medical Documentation and Information (DAHTA DIMDI) [National expert standards in nursing care]
2021 NIHR Health Technology Assessment programme Intratumoural immune signature to identify patients with primary colorectal cancer who do not require follow-up after resection: an observational study
2021 NIHR Health Technology Assessment programme Venous access devices for the delivery of long-term chemotherapy: the CAVA three-arm RCT
2021 NIHR Health Technology Assessment programme Assistive technology and telecare to maintain independent living at home for people with dementia: the ATTILA RCT
2021 NIHR Health Technology Assessment programme Palliative radiotherapy combined with stent insertion to reduce recurrent dysphagia in oesophageal cancer patients: the ROCS RCT
2021 NIHR Health Technology Assessment programme Preoperative intravenous iron for anaemia in elective major open abdominal surgery: the PREVENTT RCT
2021 NIHR Health Technology Assessment programme A high-dose 24-hour tranexamic acid infusion for the treatment of significant gastrointestinal bleeding: HALT-IT RC
2021 NIHR Health Technology Assessment programme POSNOC-POsitive Sentinel NOde: adjuvant therapy alone versus adjuvant therapy plus Clearance or axillary radiotherapy: a randomised controlled trial of axillary treatment in women with early-stage breast cancer who have metastases in one or two sentinel nodes
2021 NIHR Health Technology Assessment programme Primary trabeculectomy versus primary glaucoma eye drops for newly diagnosed advanced glaucoma: TAGS RCT
2021 NIHR Health Technology Assessment programme Sacral nerve stimulation versus the magnetic sphincter augmentation device for adult faecal incontinence: the SaFaRI RCT
2021 NIHR Health Technology Assessment programme Adrenaline to improve survival in out-of-hospital cardiac arrest: the PARAMEDIC2 RCT
2021 German Agency for Health Technology Assessment at the German Institute for Medical Documentation and Information (DAHTA DIMDI) [Gender-specific differences in drug effects. Exemplary analysis based on beta-adrenoceptor antagonists as cardiac therapy and antidepressants as psychotropic drugs]
2021 German Agency for Health Technology Assessment at the German Institute for Medical Documentation and Information (DAHTA DIMDI) [Smoking bans in public places]
2021 German Agency for Health Technology Assessment at the German Institute for Medical Documentation and Information (DAHTA DIMDI) [Radiation exposure by medical X-ray applications]
2021 German Agency for Health Technology Assessment at the German Institute for Medical Documentation and Information (DAHTA DIMDI) [Music therapy for adolescents with mental and behavioural disorders]
2021 German Agency for Health Technology Assessment at the German Institute for Medical Documentation and Information (DAHTA DIMDI) [Effects of life style changes in persons with prediabetes]
2021 German Agency for Health Technology Assessment at the German Institute for Medical Documentation and Information (DAHTA DIMDI) [Mistletoe therapy with breast cancer]
2021 German Agency for Health Technology Assessment at the German Institute for Medical Documentation and Information (DAHTA DIMDI) [Coping strategies in complex medical situations - the example of coronary heart disease]
2021 German Agency for Health Technology Assessment at the German Institute for Medical Documentation and Information (DAHTA DIMDI) [The potential influence of socio-demographical factors on access to and results of rehabilitation]
2021 German Agency for Health Technology Assessment at the German Institute for Medical Documentation and Information (DAHTA DIMDI) [Speech therapy for aphasia]
2021 NIHR Health Technology Assessment programme Understanding health-care outcomes of older people with cognitive impairment and/or dementia admitted to hospital: a mixed-methods study
2021 NIHR Health Technology Assessment programme Paclitaxel-assisted balloon angioplasty of venous stenosis in haemodialysis access: PAVE RCT
2021 NIHR Health Technology Assessment programme Prospective randomised marker-based trial to assess the clinical utility and safety of biomarker-guided immunosuppression withdrawal in liver transplantation
2021 NIHR Health Technology Assessment programme Long limb compared with standard limb Roux-en-Y gastric bypass for type 2 diabetes and obesity: the LONG LIMB RCT
2021 NIHR Health Technology Assessment programme Thoracoscopic surgical ablation versus catheter ablation as first-line treatment for long-standing persistent atrial fibrillation: the CASA-AF RCT
2021 NIHR Health Technology Assessment programme Co-trimoxazole to reduce mortality, transplant, or unplanned hospitalisation in people with moderate to very severe idiopathic pulmonary fibrosis: the EME-TIPAC RCT
2021 NIHR Health Technology Assessment programme The Arabin pessary to prevent preterm birth in women with a twin pregnancy and a short cervix: the STOPPIT 2 RCT
2021 NIHR Health Technology Assessment programme Radiation versus Observation following surgical resection of Atypical Meningioma: a randomised controlled trial (The ROAM trial)
2021 NIHR Health Technology Assessment programme Preventing enduring behavioural problems in young children through early psychological intervention: Healthy Start, Happy Start
2021 NIHR Health Technology Assessment programme A randomized controlled trial to study the effectiveness of laser ablation versus observation to prevent anal cancer in men with human immunodeficiency virus who have high-grade anal intraepithelial neoplasia
2021 NIHR Health Technology Assessment programme Tranexamic acid to reduce head injury death in people with traumatic brain injury: the CRASH-3 international RCT
2021 NIHR Health Technology Assessment programme A Phase II randomised clinical trial of conditioning cyclophosphamide and chemoembolisation with or without vaccination with dendritic cells pulsed with HepG2 lysate ex vivo in patients with Hepatocellular Carcinoma: IMMUNOTACE
2021 NIHR Public Health Research (PHR) programme A school-based, peer-led programme to increase physical activity among 13- to 14-year-old adolescents: the GoActive cluster RCT
2021 NIHR Health Technology Assessment programme Social recovery therapy for young people with emerging severe mental illness: the Prodigy RCT
2021 NIHR Health Technology Assessment programme Bisphosphonates to reduce bone fractures in stage 3B+ chronic kidney disease: a propensity score-matched cohort study
2021 NIHR Health Technology Assessment programme A prognostic model, including quantitative fetal fibronectin, to predict preterm labour: the QUIDS meta-analysis and prospective cohort study
2021 NIHR Public Health Research (PHR) programme Mental health support and training to improve secondary school teachers’ well-being: the WISE cluster RCT
2021 NIHR Health Technology Assessment programme High Or Low Dose Syntocinon for delay in labour (HOLDS)
2021 NIHR Health Technology Assessment programme Cognitive therapy compared with CBT for social anxiety disorder in adolescents: a feasibility study
2021 NIHR Health Technology Assessment programme Prognostic models of survival in patients with advanced incurable cancer: the PiPS2 observational study
2021 NIHR Health Technology Assessment programme Estimating the benefits and harms of Z-drugs for people with dementia and sleep disorders
2021 NIHR Health Technology Assessment programme A randomised pragmatic trial comparing the clinical and cost effectiveness of lithium and quetiapine augmentation in treatment resistant depression.
2021 NIHR Health Technology Assessment programme Statin Web-based Investigation of Side Effects Trial (Statin WISE Trial)
2021 NIHR Health Technology Assessment programme Prognostic indicators of severe disease in late preterm pre-eclampsia to guide decision making on timing of delivery: the PEACOCK study
2021 NIHR Health Technology Assessment programme The ACUTE (Ambulance CPAP: Use, Treatment effect and Economics) feasibility study: a pilot randomised controlled trial of prehospital CPAP for acute respiratory failure
2021 NIHR Health Technology Assessment programme CONservative TReatment of Appendicitis in Children a randomised controlled Trial CONTRACT (Feasibility study)
2021 NIHR Health Services and Delivery Research programme Acute day units in non-residential settings for people in mental health crisis: the AD-CARE mixed-methods study
2021 NIHR Health Technology Assessment programme Minimally invasive thoracoscopically-guided right minithoracotomy versus conventional sternotomy for mitral valve repair: a multicentre randomised controlled trial (UK Mini Mitral)
2021 NIHR Health Technology Assessment programme Antidepressant medication to prevent depression relapse in primary care: the ANTLER RCT
2021 NIHR Health Services and Delivery Research programme Models of generalist and specialist care in smaller acute hospitals: an exploratory study
2021 NIHR Health Technology Assessment programme Facilitating the return to work of NHS staff with common mental health disorders: a feasibility study
2021 NIHR Health Services and Delivery Research programme Progressive exercise compared with best-practice advice, with or without corticosteroid injection, for rotator cuff disorders: the GRASP factorial RCT
2021 NIHR Public Health Research (PHR) programme The VIP trial: a randomised controlled trial of the clinical and cost effectiveness of a Victim Improvement Package (VIP) for the reduction of chronic symptoms of depression or anxiety in older victims of common crime
2021 NIHR Public Health Research (PHR) programme Does slip resistant footwear reduce slips among healthcare workers? A randomised controlled trial
2021 NIHR Health Technology Assessment programme Smoking cessation medicines and e-cigarettes: a systematic review, network meta-analysis and cost-effectiveness analysis
2021 NIHR Public Health Research (PHR) programme An online family-based self-monitoring and goal-setting intervention to improve children’s physical activity: the FRESH feasibility trial and three-arm pilot RCT
2021 NIHR Health Services and Delivery Research programme Accounting for multimorbidity, competing risk and direct treatment disutility in risk prediction tools and model-based cost-effectiveness analysis for the primary prevention of cardiovascular disease and osteoporotic fracture
2021 NIHR Public Health Research (PHR) programme RISKIT-CJS Pragmatic randomized controlled trial to evaluate the effectiveness and cost-effectiveness of a multi-component intervention to reduce substance use and risk-behaviour in adolescents engaged with the criminal justice system
2021 NIHR Public Health Research (PHR) programme Evaluating graduated progress towards and impacts of the implementation of indoor smoke free prison facilities in Scotland
2021 NIHR Health Technology Assessment programme Improving the Wellbeing of people with Opioid Treated CHronic pain; I-WOTCH
2021 NIHR Health Technology Assessment programme The cystic fibrosis (CF) anti-staphylococcal antibiotic prophylaxis trial (CF START); a randomised registry trial to assess the safety and efficacy of flucloxacillin as a longterm prophylaxis agent for infants with CF
2021 NIHR Health Technology Assessment programme UK Cohort study to Investigate the prevention of Parastomal Hernia (CIPHER)
2021 Scientific Advice Unit, avalia-t; The Galician Health Knowledge Agency (ACIS) [Clinical Practice Guideline on adult's palliative care]
2021 Swiss Federal Office of Public Health (FOPH) Statins in the primary prevention of cardiovascular events and mortality in Switzerland
2021 Swiss Federal Office of Public Health (FOPH) Vertebroplasty or kyphoplasty in painful osteoporotic vertebral compression fractures unresponsive to non-surgical treatment
2021 Swiss Federal Office of Public Health (FOPH) Chondroitin sulfate in osteoarthritis
2021 Health Technology Wales (HTW) Corneal crosslinking to treat adults and children with keratoconus
2021 Health Technology Wales (HTW) Freestyle Libre flash glucose monitoring for the management of diabetes
2021 The Federal Joint Committee (G-BA) [Pharmaceutical Directive/Annex XII: Afamelanotide (Reassessment after the deadline: Phototoxicity in erythropoietic protoporphyria (EPP))]
2021 Ontario Health Enhanced Visualization Methods for First Transurethral Resection of Bladder Tumour in Suspected Non-muscle-invasive Bladder Cancer: A Health Technology Assessment
2021 Ontario Health Internet-delivered cognitive behavioral therapy for post-traumatic stress disorder and acute stress disorder
2021 Ontario Health iStent for Adults With Glaucoma: A Health Technology Assessment
2021 Ontario Health DPYD Genotyping in Patients Who Have Planned Cancer Treatment With Fluoropyrimidines
2021 Ontario Health Multi-gene Pharmacogenomic Testing That Includes Decision-Support Tools to Guide Medication Selection for Major Depression: A Health Technology Assessment
2021 Ontario Health Nonthermal endovenous treatments for varicose veins
2021 Ontario Health Prostatic artery embolization for benign prostatic hyperplasia
2021 Ontario Health Skin substitutes for adults with diabetic foot ulcers and venous leg ulcers
2021 Ontario Health Repetitive Transcranial Magnetic Stimulation for People With Treatment-Resistant Depression
2021 Ontario Health Pigmented lesion assay for suspected melanoma lesions
2021 Ontario Health Proton Beam Therapy for Cancer in Children and Adults: A Health Technology Assessment
2021 Ontario Health Use of B-Type Natriuretic Peptide (BNP) and N-Terminal proBNP (NT-proBNP) as Diagnostic Tests in Adults With Suspected Heart Failure
2021 Ontario Health Vaginal pessaries for pelvic organ prolapse and stress urinary incontinence
2021 Institut national d'excellence en sante et en services sociaux (INESSS) [Report: use of the SpaceOAR hydrogel rectal spacer during prostate radiotherapy]
2021 Scottish Medicines Consortium (SMC) Secukinumab for the treatment of active non-radiographic axial spondyloarthritis with objective signs of inflammation as indicated by elevated C-reactive protein (CRP) and/or magnetic resonance imaging (MRI) evidence in adults who have responded inadequately to nonsteroidal anti-inflammatory drugs (NSAIDs)
2021 Scottish Medicines Consortium (SMC) Brentuximab vedotin in combination with cyclophosphamide, doxorubicin and prednisone (CHP) is indicated for adult patients with previously untreated systemic anaplastic large cell lymphoma (sALCL)
2021 Scottish Medicines Consortium (SMC) Melatonin (Slenyto) for the treatment of insomnia in children and adolescents aged 2-18 with autism spectrum disorder (ASD) and / or Smith-Magenis syndrome, where sleep hygiene measures have been insufficient
2021 Scottish Medicines Consortium (SMC) Fostamatinib treatment of chronic immune thrombocytopenia in adult patients who are refractory to other treatments
2021 Scottish Medicines Consortium (SMC) Entrectinib for the treatment of patients with ROS1-positive, advanced non-small-cell lung cancer (NSCLC) not previously treated with ROS-1 inhibitors
2021 Institut national d'excellence en sante et en services sociaux (INESSS) [Report: advisability of using molecular tests to clarify the diagnosis of thyroid nodules with indeterminate cytology]
2021 Institut national d'excellence en sante et en services sociaux (INESSS) [Report: noninvasive fetal RhD genotyping using maternal plasma]
2021 Institut national d'excellence en sante et en services sociaux (INESSS) [State of knowledge: artificial intelligence-assisted diabetic retinopathy tele-screening]
2021 NIHR Health Technology Assessment programme Enzyme-linked immunosorbent assays for monitoring TNF-alpha inhibitors and antibody levels in people with rheumatoid arthritis: a systematic review and economic evaluation
2021 Norwegian Institute of Public Health (NIPH) Hydrogel rectal spacer SpaceOAR in prostate cancer radiation therapy - health economic evaluation
2021 Norwegian Institute of Public Health (NIPH) Transcatheter aortic valve implantation (TAVI) versus surgical aortic valve replacement (SAVR) for patients with severe aortic stenosis and low surgical risk and across surgical risk groups: a health technology assessment
2021 NIHR Health Technology Assessment programme Cognitive–behavioural therapy for a variety of conditions: an overview of systematic reviews and panoramic meta-analysis
2021 NIHR Health Technology Assessment programme Patch augmentation surgery for rotator cuff repair: the PARCS mixed-methods feasibility study
2021 NIHR Health Services and Delivery Research programme Respite care and short breaks for young adults aged 18–40 with complex health-care needs: mixed-methods systematic review and conceptual framework development