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Year	Source	Title
2021	Institut national d'excellence en sante et en services sociaux (INESSS)	[State of knowledge: efficacy and safety of buprenorphine and methadone for the treatment of opioid use disorder]
2021	NIHR Health Technology Assessment programme	CONservative TReatment of Appendicitis in Children a randomised controlled Trial CONTRACT (Feasibility study)
2021	Institut national d'excellence en sante et en services sociaux (INESSS)	[State of knowledge: challenging behaviours - best practices in prevention, assessment and Intervention for people with an intellectual disability, physical disability or autism spectrum disorder]
2021	NIHR Health Services and Delivery Research programme	Acute Day Units as Crisis Alternatives to Residential Care AD-CARE
2021	Institut national d'excellence en sante et en services sociaux (INESSS)	[Guidelines and standards: oral opioid agonists for the treatment of opioid use disorder]
2021	Center for Evidence-based Practice (CEP)	COVID-19: effects of vaccines on fertility and pregnancy outcomes
2021	NIHR Health Technology Assessment programme	Minimally invasive thoracoscopically-guided right minithoracotomy versus conventional sternotomy for mitral valve repair: a multicentre randomised controlled trial (UK Mini Mitral)
2021	Institut national d'excellence en sante et en services sociaux (INESSS)	[State of knowledge: organization of care and services related to alternate levels of care (ALC)]
2021	NIHR Health Technology Assessment programme	Optimal Pathway for TreatIng neurOpathic paiN in Diabetes Mellitus (OPTION-DM) trial
2021	NIHR Health Technology Assessment programme	Understanding health-care outcomes of older people with cognitive impairment and/or dementia admitted to hospital: a mixed-methods study
2021	NIHR Health Technology Assessment programme	Antidepressants to prevent relapse in depression
2021	NIHR Health Technology Assessment programme	BioImpedance Spectroscopy To maintain Renal Output: the BISTRO trial
2021	NIHR Health Services and Delivery Research programme	Models of generalist and specialist care in smaller acute hospitals: an exploratory study
2021	Institut national d'excellence en sante et en services sociaux (INESSS)	[Report: noninvasive fetal RhD genotyping using maternal plasma]
2021	Scottish Health Technologies Group (SHTG)	Detection of paroxysmal atrial fibrillation in patients with newly diagnosed ischaemic stroke
2021	Swiss Federal Office of Public Health (FOPH)	Statins in the primary prevention of cardiovascular events and mortality in Switzerland
2021	NIHR Health Technology Assessment programme	Testing strategies for Lynch syndrome in people with endometrial cancer: systematic reviews and economic evaluation
2021	Swiss Federal Office of Public Health (FOPH)	Vertebroplasty or kyphoplasty in painful osteoporotic vertebral compression fractures unresponsive to non-surgical treatment
2021	Swiss Federal Office of Public Health (FOPH)	Chondroitin sulfate in osteoarthritis
2021	NIHR Health Technology Assessment programme	DRAFFT 2: Distal Radius Acute Fracture Fixation Trial 2
2021	Institut national d'excellence en sante et en services sociaux (INESSS)	[State of knowledge: artificial intelligence-assisted diabetic retinopathy tele-screening]
2021	NIHR Health Technology Assessment programme	Intratumoural immune signature to identify patients with primary colorectal cancer who do not require follow-up after resection: an observational study
2021	NIHR Health Technology Assessment programme	The Prognosis in Palliative care Study II (PiPS2)
2021	Scientific Advice Unit, avalia-t; The Galician Health Knowledge Agency (ACIS)	[Extracorporeal membrane oxygenation for out-of-hospital cardiac arrest]
2021	Scientific Advice Unit, avalia-t; The Galician Health Knowledge Agency (ACIS)	[Home enteral nutrition in older patients with severe protein-energy malnutrition after hip fracture]
2021	NIHR Health Technology Assessment programme	Enzyme-linked immunosorbent assays for monitoring TNF-alpha inhibitors and antibody levels in people with rheumatoid arthritis: a systematic review and economic evaluation
2021	NIHR Health Technology Assessment programme	Fall prevention interventions in primary care to reduce fractures and falls in people aged 70 years and over: the PreFIT three-arm cluster RCT
2021	Norwegian Institute of Public Health (NIPH)	Hydrogel rectal spacer SpaceOAR in prostate cancer radiation therapy - health economic evaluation
2021	NIHR Health Technology Assessment programme	Venous access devices for the delivery of long-term chemotherapy: the CAVA three-arm RCT
2021	Norwegian Institute of Public Health (NIPH)	Transcatheter aortic valve implantation (TAVI) versus surgical aortic valve replacement (SAVR) for patients with severe aortic stenosis and low surgical risk and across surgical risk groups: a health technology assessment
2021	NIHR Health Technology Assessment programme	Long limb compared with standard limb Roux-en-Y gastric bypass for type 2 diabetes and obesity: the LONG LIMB RCT
2021	Scientific Advice Unit, avalia-t; The Galician Health Knowledge Agency (ACIS)	[Bronchial thermoplasty in severe asthma]
2021	Scientific Advice Unit, avalia-t; The Galician Health Knowledge Agency (ACIS)	[Radiofrequency ablation for treatment of symptomatic uterine myomas]
2021	Scientific Advice Unit, avalia-t; The Galician Health Knowledge Agency (ACIS)	[Vascular access systems for the creation of percutaneous arteriovenous hemodialysis fistula. Horizon Scanning Technologies]
2021	Scientific Advice Unit, avalia-t; The Galician Health Knowledge Agency (ACIS)	[Electromagnetic navigation bronchocopy with or without assisted robotics: use in lung nodules diagnosing process. Horizon Scanning Technologies]
2021	Scientific Advice Unit, avalia-t; The Galician Health Knowledge Agency (ACIS)	[Electromagnetic navigation bronchoscopy: use in lung nodules placement markers and resection process. Horizon Scanning Technologies]
2021	NIHR Health Services and Delivery Research programme	REhabilitation and recovery of peopLE with Aphasia after StrokE (RELEASE): Utilizing secondary data to enhance speech and language therapy interventions for people with aphasia after stroke
2021	NIHR Health Technology Assessment programme	Early switch to oral antibiotic therapy in patients with low risk neutropenic sepsis (The EASI-SWITCH Trial)
2021	NIHR Public Health Research (PHR) programme	Safetxt:A randomised controlled trial of an intervention delivered by mobile phone messaging to reduce sexually transmitted infections (STI) by increasing sexual health precaution behaviours in young people.
2021	NIHR Health Technology Assessment programme	HTA-SYMBAD StudY of Mirtazapine or carBamazepine for Agitation in Dementia
2021	NIHR Health Technology Assessment programme	Sacral nerve stimulation versus the magnetic sphincter augmentation device for adult faecal incontinence: the SaFaRI RCT
2021	NIHR Health Technology Assessment programme	Cognitive–behavioural therapy for a variety of conditions: an overview of systematic reviews and panoramic meta-analysis
2021	NIHR Health Technology Assessment programme	Patch augmentation surgery for rotator cuff repair: the PARCS mixed-methods feasibility study
2021	NIHR Health Services and Delivery Research programme	Respite care and short breaks for young adults aged 18–40 with complex health-care needs: mixed-methods systematic review and conceptual framework development
2021	Norwegian Institute of Public Health (NIPH)	Surgery for carpal tunnel syndrome: a health technology assessment
2021	NIHR Health Technology Assessment programme	Universal late pregnancy ultrasound screening to predict adverse outcomes in nulliparous women: a systematic review and cost-effectiveness analysis
2021	Norwegian Institute of Public Health (NIPH)	Evaluation of tests for FLT3 mutations in acute myeloid leukaemia (AML)
2021	NIHR Health Technology Assessment programme	DISC: Dupuytren's Interventions Surgery vs. Collagenase. A pragmatic multi-centre randomised controlled non-inferiority, cost effectiveness trial comparing injections of collagenase into the cord to surgical correction in the treatment of moderate Dupuytren's contracture in adult patients
2021	Norwegian Institute of Public Health (NIPH)	Subacromial decompression surgery for impingement syndrome: rapid health technology assessment
2021	NIHR Health Technology Assessment programme	Assistive technology and telecare to maintain independent living at home for people with dementia: the ATTILA RCT
2021	Scientific Advice Unit, avalia-t; The Galician Health Knowledge Agency (ACIS)	Clinical Practice Guideline on palliative care (Update)
2021	NIHR Health Technology Assessment programme	Impact of multiparametric MRI on staging and management of patients with suspected or confirmed ovarian cancer Short title: MR in Ovarian Cancer (MROC study)
2021	NIHR Health Services and Delivery Research programme	Pay More Attention: a national mixed methods study to identify the barriers and facilitators to ensuring equal access to high quality hospital care and services for children and young people with learning disability and their families
2021	NIHR Health Technology Assessment programme	UK Cohort study to Investigate the prevention of Parastomal Hernia (CIPHER)
2021	Institut national d'excellence en sante et en services sociaux (INESSS)	[Guidelines and standards: initiating pharmacological treatment for clearing an occluded central venous access device (CVAD)]
2021	Norwegian Institute of Public Health (NIPH)	[Intravenous immunoglobulin treatment in children with PANS/PANDAS conditions]
2021	Institut national d'excellence en sante et en services sociaux (INESSS)	[Report: Hemlibra(emicizumab) – Hemophilia A without inhibitor (re evaluation)]
2021	Institut national d'excellence en sante et en services sociaux (INESSS)	[Lyme disease and persistent symptoms: a look at the current knowledge and recommendations for improving management]
2021	Institut national d'excellence en sante et en services sociaux (INESSS)	[Report: clinical utility of the different Western blot antigen profiles in the context of disseminated Lyme disease]
2021	Institut national d'excellence en sante et en services sociaux (INESSS)	[State of knowledge: chronic” Lyme disease: current state of knowledge and overview of the different perspectives]
2021	NIHR Health Technology Assessment programme	Prognostic tools for identification of high risk in people with Crohn’s disease: systematic review and cost-effectiveness study
2021	Scottish Medicines Consortium (SMC)	Afamelanotide (Scenesse) for prevention of photoxicity in adult patients with erythropoietic protoporphyria (EPP)
2021	NIHR Health Technology Assessment programme	A multicentre randomised controlled trial of induced endometrial trauma in women undergoing first time In Vitro Fertilisation (IVF)
2021	Scottish Medicines Consortium (SMC)	Upadacitinib for the treatment of moderate to severe active rheumatoid arthritis in adult patients who have responded inadequately to, or who are intolerant to one or more disease-modifying anti-rheumatic drugs (DMARDs)
2021	NIHR Health Technology Assessment programme	Risks and benefits of bisphosphonate use in patients with chronic kidney disease: a population-based cohort study
2021	Scottish Medicines Consortium (SMC)	Ravulizumab for the treatment of adult patients with paroxysmal nocturnal haemoglobinuria (PNH): in patients with haemolysis with clinical symptom(s) indicative of high disease activity; in patients who are clinically stable after having been treated with eculizumab for at least the past 6 months
2021	NIHR Health Technology Assessment programme	Facilitating the return to work of NHS staff with common mental health disorders: a feasibility study
2021	Scottish Medicines Consortium (SMC)	Ozanimod for adult patients with relapsing remitting multiple sclerosis
2021	NIHR Health Technology Assessment programme	QUIDS Quantitative fibronectin to help decision-making in women with symptoms of preterm labour
2021	NIHR Health Technology Assessment programme	The Invasive Dentistry Endocarditis Association Study: the IDEA Study
2021	Scottish Medicines Consortium (SMC)	Entrectinib as monotherapy for the treatment of adult and paediatric patients 12 years of age and older with solid tumours expressing a neurotrophic tyrosine receptor kinase (NTRK) gene fusion: who have a disease that is locally advanced, metastatic or where surgical resection is likely to result in severe morbidity; and who have not received a prior NTRK inhibitor; who have no satisfactory treatment options
2021	NIHR Health Technology Assessment programme	Palliative radiotherapy combined with stent insertion to reduce recurrent dysphagia in oesophageal cancer patients: the ROCS RCT
2021	NIHR Health Technology Assessment programme	Co-trimoxazole to reduce mortality, transplant, or unplanned hospitalisation in people with moderate to very severe idiopathic pulmonary fibrosis: the EME-TIPAC RCT
2021	Scottish Medicines Consortium (SMC)	Onasemnogene abeparvovec treatment of patients with 5q spinal muscular atrophy (SMA) with a bi-allelic mutation in the SMN1 gene and a clinical diagnosis of SMA type 1, or patients with 5q SMA with a bi-allelic mutation in the SMN1 gene and up to 3 copies of the SMN2 gene
2021	Institut national d'excellence en sante et en services sociaux (INESSS)	[Report: validation of the management framework for a nonspecific human immunoglobulin shortage]
2021	Institut national d'excellence en sante et en services sociaux (INESSS)	[Guidelines and standards: standards for the management of acute ST-segment elevation myocardial infarction (STEMI) in Québec (update of April 2021)]
2021	Swedish Agency for Health Technology Assessment and Assessment of Social Services (SBU)	Internet-based psychological treatment for anxiety and depression (an update)
2021	Scottish Health Technologies Group (SHTG)	NHSScotland COPD Support Service: remote and self-management of high-risk patients with COPD using a web app and machine learning predictive modelling
2021	Swedish Agency for Health Technology Assessment and Assessment of Social Services (SBU)	Occupational exposure and upper extremity pain
2021	Swedish Agency for Health Technology Assessment and Assessment of Social Services (SBU)	Diagnostics and treatment of provoked vestibulodynia
2021	Swedish Agency for Health Technology Assessment and Assessment of Social Services (SBU)	Continuity of care
2021	Institute for Clinical Effectiveness and Health Policy (IECS)	[Ketoanalogs in association with high protein diet in chronic kidney failure]
2021	Swedish Agency for Health Technology Assessment and Assessment of Social Services (SBU)	Dietary treatment of diabetes
2021	Institute for Clinical Effectiveness and Health Policy (IECS)	[Precice® motorized intramedullary nail system for limb-length discrepancy]
2021	Swedish Agency for Health Technology Assessment and Assessment of Social Services (SBU)	Diagnosis and treatment of lipedema
2021	Institute for Clinical Effectiveness and Health Policy (IECS)	[Direct-acting oral anticoagulants for postoperative thrombosis prophylaxis]
2021	Swedish Agency for Health Technology Assessment and Assessment of Social Services (SBU)	Complex interventions for chronic pain
2021	Institute for Clinical Effectiveness and Health Policy (IECS)	[Genetic testing for lynch syndrome in colorectal cancer and family members]
2021	Swedish Agency for Health Technology Assessment and Assessment of Social Services (SBU)	Childbirth with Caesarean section on the pregnant woman's request - advantages and disadvantages for the mother and child
2021	NIHR Public Health Research (PHR) programme	School-based interventions to prevent anxiety, depression and conduct disorder in children and young people: a systematic review and network meta-analysis
2021	Center for Evidence-based Practice (CEP)	Opioid pain assessment
2021	Center for Evidence-based Practice (CEP)	Effectiveness of intra-operative antimicrobial irrigation to prevent surgical site infection in clean surgeries
2021	Swedish Agency for Health Technology Assessment and Assessment of Social Services (SBU)	Treatment and rehabilitation of people with fibromyalgia
2021	Institut national d'excellence en sante et en services sociaux (INESSS)	[State of practice: long-term left ventricular assist devices, real-world evolving portrait of use and outcomes in Québec from 2010 to 2017]
2021	Swedish Agency for Health Technology Assessment and Assessment of Social Services (SBU)	Programs for prevention of suicide and suicidal attempts in children and adolescents
2021	Institut national d'excellence en sante et en services sociaux (INESSS)	[Guidelines and standards: alcohol withdrawal and relapse prevention]
2021	NIHR Health Technology Assessment programme	The Arabin pessary to prevent preterm birth in women with a twin pregnancy and a short cervix: the STOPPIT 2 RCT
2021	Institut national d'excellence en sante et en services sociaux (INESSS)	[Report: relevance of using mpMRI for the diagnostic investigation of prostate cancer - mpMRI and prostate cancer diagnosis]
2021	NIHR Public Health Research (PHR) programme	A cluster randomised controlled trial to evaluate the effectiveness and cost-effectiveness of the GoActive programme to increase physical activity among 13-14 year-old adolescents
2021	Institut national d'excellence en sante et en services sociaux (INESSS)	[Report: optimal use of immunoglobulins in rheumatology. Report in support of the optimal use guide English summary]