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Year Source Title
2021     Scottish Medicines Consortium (SMC) Fostamatinib treatment of chronic immune thrombocytopenia in adult patients who are refractory to other treatments
2021     Scottish Medicines Consortium (SMC) Entrectinib for the treatment of patients with ROS1-positive, advanced non-small-cell lung cancer (NSCLC) not previously treated with ROS-1 inhibitors
2021     NIHR Health Technology Assessment programme Comprehensive ascertainment of bleeding in patients prescribed different combinations of dual antiplatelet therapy (DAPT) and triple therapy (TT, DAPT plus an anticoagulant) after coronary interventions in the UK: a population based cohort study The ADAPTT Study
2021     NIHR Health Technology Assessment programme EMPOWER: Early Signs Monitoring to Prevent Relapse and PrOmote Wellbeing, Engagement and Recovery
2021     NIHR Health Technology Assessment programme A tailored, psychological intervention for mild to moderate anxiety or depression in people with chronic obstructive pulmonary disease(COPD) (TANDEM Tailored intervention for ANxiety and DEpression Management in COPD)
2021     NIHR Health Technology Assessment programme High Or Low Dose Syntocinon for delay in labour (HOLDS)
2021     NIHR Health Technology Assessment programme Specific versus generic psychological therapy for adolescents with social anxiety disorder: a comparison of Clark & Wells condition-specific cognitive therapy adapted for adolescents, with the generic cognitive behaviour therapy that is currently used in adolescent services
2021     Institut national d'excellence en sante et en services sociaux (INESSS) [Report: advisability of using molecular tests to clarify the diagnosis of thyroid nodules with indeterminate cytology]
2021     NIHR Health Technology Assessment programme CONservative TReatment of Appendicitis in Children a randomised controlled Trial CONTRACT (Feasibility study)
2021     NIHR Health Services and Delivery Research programme Acute Day Units as Crisis Alternatives to Residential Care AD-CARE
2021     NIHR Health Technology Assessment programme Minimally invasive thoracoscopically-guided right minithoracotomy versus conventional sternotomy for mitral valve repair: a multicentre randomised controlled trial (UK Mini Mitral)
2021     NIHR Health Technology Assessment programme Optimal Pathway for TreatIng neurOpathic paiN in Diabetes Mellitus (OPTION-DM) trial
2021     NIHR Health Technology Assessment programme Antidepressants to prevent relapse in depression
2021     NIHR Health Technology Assessment programme BioImpedance Spectroscopy To maintain Renal Output: the BISTRO trial
2021     NIHR Health Services and Delivery Research programme Models of generalist and specialist care in smaller acute hospitals: an exploratory study
2021     Institut national d'excellence en sante et en services sociaux (INESSS) [Report: noninvasive fetal RhD genotyping using maternal plasma]
2021     NIHR Health Technology Assessment programme DRAFFT 2: Distal Radius Acute Fracture Fixation Trial 2
2021     Institut national d'excellence en sante et en services sociaux (INESSS) [State of knowledge: artificial intelligence-assisted diabetic retinopathy tele-screening]
2021     NIHR Health Technology Assessment programme The Prognosis in Palliative care Study II (PiPS2)
2021     Scientific Advice Unit, avalia-t; The Galician Health Knowledge Agency (ACIS) [Extracorporeal membrane oxygenation for out-of-hospital cardiac arrest]
2021     Scientific Advice Unit, avalia-t; The Galician Health Knowledge Agency (ACIS) [Home enteral nutrition in older patients with severe protein-energy malnutrition after hip fracture]
2021     NIHR Health Technology Assessment programme Enzyme-linked immunosorbent assays for monitoring TNF-alpha inhibitors and antibody levels in people with rheumatoid arthritis: a systematic review and economic evaluation
2021     Norwegian Institute of Public Health (NIPH) Hydrogel rectal spacer SpaceOAR in prostate cancer radiation therapy - health economic evaluation
2021     Norwegian Institute of Public Health (NIPH) Transcatheter aortic valve implantation (TAVI) versus surgical aortic valve replacement (SAVR) for patients with severe aortic stenosis and low surgical risk and across surgical risk groups: a health technology assessment
2021     Scientific Advice Unit, avalia-t; The Galician Health Knowledge Agency (ACIS) [Bronchial thermoplasty in severe asthma]
2021     Scientific Advice Unit, avalia-t; The Galician Health Knowledge Agency (ACIS) [Radiofrequency ablation for treatment of symptomatic uterine myomas]
2021     Scientific Advice Unit, avalia-t; The Galician Health Knowledge Agency (ACIS) [Vascular access systems for the creation of percutaneous arteriovenous hemodialysis fistula. Horizon Scanning Technologies]
2021     Scientific Advice Unit, avalia-t; The Galician Health Knowledge Agency (ACIS) [Electromagnetic navigation bronchocopy with or without assisted robotics: use in lung nodules diagnosing process. Horizon Scanning Technologies]
2021     Scientific Advice Unit, avalia-t; The Galician Health Knowledge Agency (ACIS) [Electromagnetic navigation bronchoscopy: use in lung nodules placement markers and resection process. Horizon Scanning Technologies]
2021     NIHR Health Services and Delivery Research programme REhabilitation and recovery of peopLE with Aphasia after StrokE (RELEASE): Utilizing secondary data to enhance speech and language therapy interventions for people with aphasia after stroke
2021     NIHR Health Technology Assessment programme Early switch to oral antibiotic therapy in patients with low risk neutropenic sepsis (The EASI-SWITCH Trial)
2021     NIHR Public Health Research (PHR) programme Safetxt:A randomised controlled trial of an intervention delivered by mobile phone messaging to reduce sexually transmitted infections (STI) by increasing sexual health precaution behaviours in young people.
2021     NIHR Health Technology Assessment programme HTA-SYMBAD StudY of Mirtazapine or carBamazepine for Agitation in Dementia
2021     NIHR Health Technology Assessment programme Cognitive–behavioural therapy for a variety of conditions: an overview of systematic reviews and panoramic meta-analysis
2021     NIHR Health Technology Assessment programme Patch augmentation surgery for rotator cuff repair: the PARCS mixed-methods feasibility study
2021     NIHR Health Services and Delivery Research programme Respite care and short breaks for young adults aged 18–40 with complex health-care needs: mixed-methods systematic review and conceptual framework development
2021     Norwegian Institute of Public Health (NIPH) Surgery for carpal tunnel syndrome: a health technology assessment
2021     NIHR Health Technology Assessment programme Universal late pregnancy ultrasound screening to predict adverse outcomes in nulliparous women: a systematic review and cost-effectiveness analysis
2021     Norwegian Institute of Public Health (NIPH) Evaluation of tests for FLT3 mutations in acute myeloid leukaemia (AML)
2021     NIHR Health Technology Assessment programme DISC: Dupuytren's Interventions Surgery vs. Collagenase. A pragmatic multi-centre randomised controlled non-inferiority, cost effectiveness trial comparing injections of collagenase into the cord to surgical correction in the treatment of moderate Dupuytren's contracture in adult patients
2021     Norwegian Institute of Public Health (NIPH) Subacromial decompression surgery for impingement syndrome: rapid health technology assessment
2021     Scientific Advice Unit, avalia-t; The Galician Health Knowledge Agency (ACIS) Clinical Practice Guideline on palliative care (Update)
2021     NIHR Health Technology Assessment programme Impact of multiparametric MRI on staging and management of patients with suspected or confirmed ovarian cancer Short title: MR in Ovarian Cancer (MROC study)
2021     NIHR Health Services and Delivery Research programme Pay More Attention: a national mixed methods study to identify the barriers and facilitators to ensuring equal access to high quality hospital care and services for children and young people with learning disability and their families
2021     NIHR Health Technology Assessment programme UK Cohort study to Investigate the prevention of Parastomal Hernia (CIPHER)
2021     Institut national d'excellence en sante et en services sociaux (INESSS) [Guidelines and standards: Initiating pharmacological treatment for clearing an occluded central venous access device (CVAD)]
2021     Norwegian Institute of Public Health (NIPH) [Intravenous immunoglobulin treatment in children with PANS/PANDAS conditions]
2021     Institut national d'excellence en sante et en services sociaux (INESSS) [Report: Hemlibra(emicizumab) – Hemophilia A without inhibitor (re evaluation)]
2021     Institut national d'excellence en sante et en services sociaux (INESSS) [Lyme disease and persistent symptoms: a look at the current knowledge and recommendations for improving management]
2021     Institut national d'excellence en sante et en services sociaux (INESSS) [Report: Clinical utility of the different Western blot antigen profiles in the context of disseminated Lyme disease]
2021     Institut national d'excellence en sante et en services sociaux (INESSS) [State of knowledge: chronic” Lyme disease: current state of knowledge and overview of the different perspectives]
2021     NIHR Health Technology Assessment programme Prognostic tools for identification of high risk in people with Crohn’s disease: systematic review and cost-effectiveness study
2021     NIHR Health Technology Assessment programme A multicentre randomised controlled trial of induced endometrial trauma in women undergoing first time In Vitro Fertilisation (IVF)
2021     NIHR Health Technology Assessment programme Risks and benefits of bisphosphonate use in patients with chronic kidney disease: a population-based cohort study
2021     NIHR Health Technology Assessment programme Facilitating the return to work of NHS staff with common mental health disorders: a feasibility study
2021     NIHR Health Technology Assessment programme QUIDS Quantitative fibronectin to help decision-making in women with symptoms of preterm labour
2021     NIHR Health Technology Assessment programme The Invasive Dentistry Endocarditis Association Study: the IDEA Study
2021     NIHR Public Health Research (PHR) programme A cluster randomised controlled trial to evaluate the effectiveness and cost-effectiveness of the GoActive programme to increase physical activity among 13-14 year-old adolescents
2021     NIHR Health Technology Assessment programme Radiation versus Observation following surgical resection of Atypical Meningioma: a randomised controlled trial (The ROAM trial)
2021     NIHR Public Health Research (PHR) programme A randomised controlled trial and economic evaluation of a community-based physical activity intervention to prevent mobility-related disability for retired older people. The REACT (REtirement in ACTion) study
2021     NIHR Health Technology Assessment programme PRODIGY: Prevention and treatment of long term social disability amongst young people with emerging severe mental illness: A randomised controlled trial
2021     NIHR Health Services and Delivery Research programme The TRECA study: TRials Engagement in Children and Adolescents
2021     NIHR Health Technology Assessment programme Estimating the benefits and harms of Z-drugs for people with dementia and sleep disorders
2021     NIHR Health Technology Assessment programme ROCkeTS - Refining Ovarian Cancer Test Accuracy Scores
2021     NIHR Health Technology Assessment programme A randomised pragmatic trial comparing the clinical and cost effectiveness of lithium and quetiapine augmentation in treatment resistant depression.
2021     NIHR Health Technology Assessment programme A multi-centre cluster randomised controlled trial to evaluate the Guide to Action Care Home fall prevention programme in care homes for older people (FinCH)
2021     NIHR Health Technology Assessment programme Investigating the effectiveness and cost effectiveness of using FITNET to treat paediatric CFS/ME in the UK
2021     NIHR Health Technology Assessment programme Statin Web-based Investigation of Side Effects Trial (Statin WISE Trial)
2021     NIHR Health Technology Assessment programme Prognostic indicators of severe disEAse in women with late preterm pre-eClampsia tO guide deCision-maKing on timing of delivery (PEACOCK study)
2021     NIHR Health Technology Assessment programme A randomised controlled trial comparing the clinical effectiveness and cost-effectiveness of laparoscopic cholecystectomy compared with observation/conservative management for preventing recurrent symptoms and complications in adults with uncomplicated symptomatic gallstones (C-Gall)
2021     NIHR Health Services and Delivery Research programme Clinical and cost effectiveness of progressive exercise compared to best practice advice, with or without corticosteroid injection, for the treatment of rotator cuff disorders: a 2x2 factorial randomised controlled trial (The GRASP trial)
2021     NIHR Health Technology Assessment programme ALternative To prophylactic Antibiotics for the treatment of Recurrent urinary tract infections in women (ALTAR study)
2021     NIHR Public Health Research (PHR) programme The VIP trial: a randomised controlled trial of the clinical and cost effectiveness of a Victim Improvement Package (VIP) for the reduction of chronic symptoms of depression or anxiety in older victims of common crime
2021     NIHR Health Technology Assessment programme A multi-centre randomised controlled trial to compare the clinical and cost effectiveness of Lee Silverman Voice Treatment versus standard NHS speech and language therapy versus control in Parkinson's disease (PD COMM)
2021     NIHR Public Health Research (PHR) programme Does slip resistant footwear reduce slips among healthcare workers? A randomised controlled trial
2021     NIHR Health Technology Assessment programme How do smoking cessation medicines compare with respect to their neuropsychiatric safety: a systematic review, network meta-analysis and cost effectiveness analysis.
2021     NIHR Health Technology Assessment programme OPTIMA: Optimal Personalised Treatment of early breast cancer usIng Multi-parameter Analysis
2021     NIHR Public Health Research (PHR) programme The impact of a family-based physical activity promotion programme on child physical activity: feasibility and pilot of the Families Reporting Every Step to Health (FRESH) intervention.
2021     NIHR Health Services and Delivery Research programme Accounting for multimorbidity, competing risk and direct treatment disutility in risk prediction tools and model-based cost-effectiveness analysis for the primary prevention of cardiovascular disease and osteoporotic fracture
2021     NIHR Public Health Research (PHR) programme RISKIT-CJS Pragmatic randomized controlled trial to evaluate the effectiveness and cost-effectiveness of a multi-component intervention to reduce substance use and risk-behaviour in adolescents engaged with the criminal justice system
2021     NIHR Public Health Research (PHR) programme Evaluating graduated progress towards and impacts of the implementation of indoor smoke free prison facilities in Scotland
2021     NIHR Health Technology Assessment programme Improving the Wellbeing of people with Opioid Treated CHronic pain; I-WOTCH
2021     NIHR Health Technology Assessment programme The cystic fibrosis (CF) anti-staphylococcal antibiotic prophylaxis trial (CF START); a randomised registry trial to assess the safety and efficacy of flucloxacillin as a longterm prophylaxis agent for infants with CF
2021     Ontario Health Blue light (fluorescence) cystoscopy with hexaminolevulinate hydrochloride in non-muscle bladder cancer
2021     Ontario Health Internet-delivered cognitive behavioral therapy for post-traumatic stress disorder and acute stress disorder
2021     Ontario Health iStent for people with open angle glaucoma
2021     Ontario Health DPYD genotyping in patients with cancer treated with fluoropyrimidines
2021     Ontario Health Multi-gene pharmacogenomic testing to guide medication selection for people with major depression
2021     NIHR Public Health Research (PHR) programme A cluster randomised controlled trial of an intervention to improve the mental health support and training available to secondary school teachers the WISE (Wellbeing in Secondary Education) project
2021     NIHR Health Technology Assessment programme The ACUTE (Ambulance CPAP: Use, Treatment effect and Economics) feasibility study: a pilot randomised controlled trial of prehospital CPAP for acute respiratory failure
2021     Ontario Health Molecular testing for thyroid nodules with atypical cells of indeterminate significance
2021     NIHR Health Technology Assessment programme A non-inferiority randomised controlled trial comparing the clinical and cost-effectiveness of one session treatment (OST) with multi-session cognitive behavioural therapy (CBT) in children with specific phobias
2021     Ontario Health Nonthermal minimally invasive treatments for varicose veins
2021     Ontario Health Prostatic artery embolization for benign prostatic hyperplasia
2021     Ontario Health Skin substitutes for adults with diabetic foot ulcers and venous leg ulcers
2021     Ontario Health Repetitive transcranial magnetic stimulation (rTMS) for people with treatment-resistant depression
2021     Ontario Health Pigmented lesion assay for suspected melanoma lesions
2021     Institut national d'excellence en sante et en services sociaux (INESSS) [Report: use of the SpaceOAR hydrogel rectal spacer during prostate radiotherapy]
2021     Ontario Health Use of B-type natriuretic peptide and N Terminal-pro B-type natriuretic peptide as diagnostic tests in people with suspected heart failure
2021     Ontario Health Vaginal pessaries for pelvic organ prolapse and stress urinary incontinence