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Year Source Title
2021     European Network for Health Technology Assessment (EUnetHTA) Anakinra for the treatment of COVID-19
2021     Health Information and Quality Authority (HIQA) Economic burden of antimicrobial resistance: an analysis of additional costs associated with resistant infections
2021     National Institute for Health and Care Excellence (NICE) Pembrolizumab for untreated metastatic colorectal cancer with high microsatellite instability or mismatch repair deficiency. NICE technology appraisal guidance 709
2021     National Institute for Health and Care Excellence (NICE) Deep brain stimulation for chronic, severe, treatment-resistant obsessive-compulsive disorder in adults. NICE interventional procedures guidance 693
2021     European Network for Health Technology Assessment (EUnetHTA) APN01 for the treatment of COVID-19
2021     Health Information and Quality Authority (HIQA) Health technology assessment of birth cohort testing for hepatitis C
2021     National Institute for Health and Care Excellence (NICE) Ravulizumab for treating atypical haemolytic uraemic syndrome. NICE technology appraisal guidance 710
2021     National Institute for Health and Care Excellence (NICE) Melphalan chemosaturation with percutaneous hepatic artery perfusion and hepatic vein isolation for primary or metastatic cancer in the liver. NICE interventional procedures guidance 691
2021     European Network for Health Technology Assessment (EUnetHTA) Darunavir for the treatment of COVID-19
2021     National Institute for Health and Care Excellence (NICE) Enzalutamide for treating hormone-sensitive metastatic prostate cancer. NICE technology appraisal guidance 712
2021     National Institute for Health and Care Excellence (NICE) Transcervical ultrasound-guided radiofrequency ablation for symptomatic uterine fibroids. NICE interventional procedures guidance 689
2021     European Network for Health Technology Assessment (EUnetHTA) Favipiravir for the treatment of COVID-19
2021     National Institute for Health and Care Excellence (NICE) Nivolumab for advanced non-squamous non-small-cell lung cancer after chemotherapy. NICE technology appraisal guidance 713
2021     National Institute for Health and Care Excellence (NICE) Extracorporeal whole liver perfusion for acute liver failure. NICE interventional procedures guidance 690
2021     European Network for Health Technology Assessment (EUnetHTA) Sarilumab for the treatment of COVID-19
2021     National Institute for Health and Care Excellence (NICE) Dasatinib for treating Philadelphia-chromosome-positive acute lymphoblastic leukaemia (terminated appraisal). NICE technology appraisal guidance 714
2021     National Institute for Health and Care Excellence (NICE) Free-functioning gracilis transfer to restore upper limb function in brachial plexus injury. NICE interventional procedures guidance 687
2021     European Network for Health Technology Assessment (EUnetHTA) Interferon (IFN) and Novaferon (NOVA) for the treatment of COVID-19
2021     Health Information and Quality Authority (HIQA) Identification of demand models for estimating the quantities of personal protective equipment (PPE) required for optimal patient care in the context of COVID-19
2021     National Institute for Health and Care Excellence (NICE) Adalimumab, etanercept, infliximab and abatacept for treating moderate rheumatoid arthritis after conventional DMARDs have failed. NICE technology appraisal guidance 715
2021     National Institute for Health and Care Excellence (NICE) Cytoreduction surgery with hyperthermic intraoperative peritoneal chemotherapy for peritoneal carcinomatosis. NICE interventional procedures guidance 688
2021     European Network for Health Technology Assessment (EUnetHTA) Gimsilumab for the treatment of COVID-19
2021     National Institute for Health and Care Excellence (NICE) Nivolumab with ipilimumab for previously treated metastatic colorectal cancer with high microsatellite instability or mismatch repair deficiency. NICE technology appraisal guidance 716
2021     National Institute for Health and Care Excellence (NICE) Self-expanding implant insertion into the intersphincteric space for faecal incontinence. NICE interventional procedures guidance 685
2021     European Network for Health Technology Assessment (EUnetHTA) Canakinumab for the treatment of COVID-19
2021     Health Information and Quality Authority (HIQA) Rapid antigen testing for screening or surveillance of asymptomatic individuals to limit transmission of SARS-CoV-2
2021     National Institute for Health and Care Excellence (NICE) Duvelisib for treating relapsed follicular lymphoma after 2 or more systemic therapies (terminated appraisal). NICE technology appraisal guidance 717
2021     National Institute for Health and Care Excellence (NICE) Minimally invasive radical hysterectomy for early stage cervical cancer. NICE interventional procedures guidance 686
2021     European Network for Health Technology Assessment (EUnetHTA) Casirivimab and imdevimab (REGN-COV2) for the treatment of COVID-19
2021     Health Information and Quality Authority (HIQA) Reduction of the minimum age for the application of mask wearing requirements and recommendations – updated advice
2021     National Institute for Health and Care Excellence (NICE) Ixekizumab for treating axial spondyloarthritis. NICE technology appraisal guidance 718
2021     NIHR Public Health Research (PHR) programme Mental health support and training to improve secondary school teachers’ well-being: the WISE cluster RCT
2021     European Network for Health Technology Assessment (EUnetHTA) Bamlanivimab for the treatment of COVID-19
2021     NIHR Health Technology Assessment programme Reducing bias in trials from reactions to measurement: the MERIT study including developmental work and expert workshop
2021     Australian Safety and Efficacy Register of New Interventional Procedures -Surgical (ASERNIP-S) Influence of COVID-19 vaccines on surgical practice
2021     National Institute for Health and Care Excellence (NICE) Secukinumab for treating non-radiographic axial spondyloarthritis. NICE technology appraisal guidance 719
2021     European Network for Health Technology Assessment (EUnetHTA) Baricitinib for the treatment of COVID-19
2021     Health Information and Quality Authority (HIQA) Analysis of factors associated with outbreaks of SARS-CoV-2 in nursing homes in Ireland
2021     Institute for Clinical and Economic Review (ICER) Tezepelumab for severe asthma
2021     Australian Safety and Efficacy Register of New Interventional Procedures -Surgical (ASERNIP-S) Proposed delay for safe surgery after COVID-19
2021     National Institute for Health and Care Excellence (NICE) Chlormethine gel for treating mycosis fungoides-type cutaneous T-cell lymphoma. NICE technology appraisal guidance 720
2021     European Network for Health Technology Assessment (EUnetHTA) Molnupiravir for the treatment of COVID-19
2021     Centre intégré universitaire de santé et de services sociaux de la Capitale-Nationale (CIUSSS) [Training programming for healthcare professionals: How to support patients with chronic diseases to self-manage their health]
2021     Institute for Clinical and Economic Review (ICER) Mavacamten for hypertrophic cardiomyopathy: effectiveness and value
2021     Australian Safety and Efficacy Register of New Interventional Procedures -Surgical (ASERNIP-S) Telehealth in surgery: an umbrella review
2021     National Institute for Health and Care Excellence (NICE) Abiraterone for treating newly diagnosed high-risk hormone-sensitive metastatic prostate cancer. NICE technology appraisal guidance 721
2021     European Network for Health Technology Assessment (EUnetHTA) High-dose vitamin D for the treatment of COVID-19
2021     Ontario Health Stance-control knee–ankle–foot orthoses for people with knee instability: a health technology assessment
2021     Institute for Clinical and Economic Review (ICER) Eculizumab and efgartigimod for the treatment of myasthenia gravis: effectiveness and value
2021     National Institute for Health and Care Excellence (NICE) Pemigatinib for treating relapsed or refractory advanced cholangiocarcinoma with FGFR2 fusion or rearrangement. NICE technology appraisal guidance 722
2021     European Network for Health Technology Assessment (EUnetHTA) Mavrilimumab for the treatment of COVID-19
2021     Austrian Institute for Health Technology Assessment (AIHTA) Stool DNA testing for colorectal cancer (CRC) screening
2021     Institute for Clinical and Economic Review (ICER) Observational real-world evidence update. Prophylaxis of hereditary angioedema with Takhzyro and C1 inhibitors: effectiveness and value
2021     National Institute for Health and Care Excellence (NICE) Bimekizumab for treating moderate to severe plaque psoriasis. NICE technology appraisal guidance 723
2021     European Network for Health Technology Assessment (EUnetHTA) Ivermectin for the treatment of COVID-19
2021     Institute of Health Economics (IHE) Optimizing vascular risk reduction initiatives in Alberta: a clinical review and economic analysis
2021     Institute for Clinical and Economic Review (ICER) JAK inhibitors and monoclonal antibodies for the treatment of atopic dermatitis: effectiveness and value
2021     National Institute for Health and Care Excellence (NICE) Nivolumab with ipilimumab and chemotherapy for untreated metastatic non-small-cell lung cancer. NICE technology appraisal guidance 724
2021     European Network for Health Technology Assessment (EUnetHTA) Aspirin for the treatment of COVID-19
2021     NIHR Health Technology Assessment programme Non-invasive imaging software to assess the functional significance of coronary stenoses: a systematic review and economic evaluation
2021     Institute for Clinical and Economic Review (ICER) Aducanumab for Alzheimer's disease: effectiveness and value
2021     National Institute for Health and Care Excellence (NICE) Abemaciclib with fulvestrant for treating hormone receptor-positive, HER2-negative advanced breast cancer after endocrine therapy. NICE technology appraisal guidance 725
2021     NIHR Health Technology Assessment programme The ACUTE (Ambulance CPAP: Use, Treatment effect and Economics) feasibility study: a pilot randomised controlled trial of prehospital CPAP for acute respiratory failure
2021     Swiss Federal Office of Public Health (FOPH) Corneal collagen crosslinking for the treatment of progressive keratoconus
2021     Institute for Clinical and Economic Review (ICER) Anti b-cell maturation antigen CAR T-cell and antibody drug conjugate therapy for heavily pre-treated relapsed and refractory multiple myeloma
2021     National Institute for Health and Care Excellence (NICE) Daratumumab with pomalidomide and dexamethasone for treating relapsed or refractory multiple myeloma (terminated appraisal). NICE technology appraisal guidance 726
2021     Swiss Federal Office of Public Health (FOPH) Infliximab reference product versus biosimilar for the treatment of rheumatoid arthritis
2021     Institute for Clinical and Economic Review (ICER) Belimumab and voclosporin for lupus nephritis: effectiveness and value
2021     National Institute for Health and Care Excellence (NICE) Isatuximab with carfilzomib and dexamethasone for treating relapsed or refractory multiple myeloma (terminated appraisal). NICE technology appraisal guidance 727
2021     Institute for Clinical and Economic Review (ICER) Treatments for anemia in chronic kidney disease: effectiveness and value
2021     National Institute for Health and Care Excellence (NICE) Midostaurin for treating advanced systemic mastocytosis. NICE technology appraisal guidance 728
2021     Swiss Federal Office of Public Health (FOPH) Medical cannabis for treating various symptoms in Switzerland
2021     Penn Medicine Center for Evidence-based Practice (CEP) Fall risk assessment in oncology patients
2021     Institute for Clinical and Economic Review (ICER) Bempedoic acid and inclisiran for patients with heterozygous familial hypercholesterolemia and for secondary prevention of ASCVD: effectiveness and value
2021     Australian Safety and Efficacy Register of New Interventional Procedures -Surgical (ASERNIP-S) Delaying surgery for patients recovering from COVID-19. A rapid review comissioned by RACS
2021     Canadian Agency for Drugs and Technologies in Health (CADTH) Phosphodiesterase type-5 inhibitors for the treatment of secondary Raynaud's phenomenon and digital ulcers
2021     National Institute for Health and Care Excellence (NICE) Sapropterin for treating hyperphenylalaninaemia in phenylketonuria. NICE technology appraisal guidance 729
2021     Swiss Federal Office of Public Health (FOPH) Palbociclib (Ibrance®), ribociclib (Kisqali®) and abemaciclib (Verzenios®) for the treatment of hormone receptor (HR)-positive, human epidermal growth factor (HER2)-negative advanced breast cancer
2021     Penn Medicine Center for Evidence-based Practice (CEP) Effects of masks on the health of schoolchildren
2021     National Institute for Health and Care Excellence (NICE) Avapritinib for treating unresectable or metastatic gastrointestinal stromal tumours (terminated appraisal). NICE technology appraisal guidance 730
2021     Ontario Health Nonthermal endovenous treatments for varicose veins
2021     Swiss Federal Office of Public Health (FOPH) Subacromial decompression as a primary/isolated intervention to treat subacromial pain
2021     NIHR Health Technology Assessment programme Smoking cessation medicines and e-cigarettes: a systematic review, network meta-analysis and cost-effectiveness analysis
2021     National Institute for Health and Care Excellence (NICE) Vericiguat for treating chronic heart failure with reduced ejection fraction (terminated appraisal). NICE technology appraisal guidance 731
2021     Ontario Health Prostatic artery embolization for benign prostatic hyperplasia
2021     Swiss Federal Office of Public Health (FOPH) The treatment of hypercholesterolaemia and mixed/combined hyperlipidaemia with ezetimibe-containing medicines
2021     Belgian Health Care Knowledge Centre (KCE) Long COVID: Pathophysiology – epidemiology and patient needs
2021     National Institute for Health and Care Excellence (NICE) Baloxavir marboxil for treating acute uncomplicated influenza (terminated appraisal). NICE technology appraisal guidance 732
2021     Ontario Health Skin substitutes for adults with diabetic foot ulcers and venous leg ulcers
2021     National Institute for Health and Care Excellence (NICE) Inclisiran for treating primary hypercholesterolaemia or mixed dyslipidaemia. NICE technology appraisal guidance 733
2021     Ontario Health Repetitive Transcranial Magnetic Stimulation for People With Treatment-Resistant Depression
2021     National Institute for Health and Care Excellence (NICE) Secukinumab for treating moderate to severe plaque psoriasis in children and young people. NICE technology appraisal guidance 734
2021     Ontario Health Pigmented lesion assay for suspected melanoma lesions
2021     National Institute for Health and Care Excellence (NICE) Tofacitinib for treating juvenile idiopathic arthritis. NICE technology appraisal guidance 735
2021     Ontario Health Proton Beam Therapy for Cancer in Children and Adults: A Health Technology Assessment
2021     National Institute for Health and Care Excellence (NICE) Nivolumab for treating recurrent or metastatic squamous cell carcinoma of the head and neck after platinum-based chemotherapy. NICE technology appraisal guidance 736
2021     Penn Medicine Center for Evidence-based Practice (CEP) COVID-19: mandatory vaccination
2021     Health Technology Wales (HTW) Handheld single lead electrocardiogram devices to detect atrial fibrillation in older adults and those with intermittent episodes
2021     National Institute for Health and Care Excellence (NICE) Pembrolizumab with platinum- and fluoropyrimidine-based chemotherapy for untreated advanced oesophageal and gastro-oesophageal junction cancer. NICE technology appraisal guidance 737
2021     Ontario Health Use of B-Type Natriuretic Peptide (BNP) and N-Terminal proBNP (NT-proBNP) as Diagnostic Tests in Adults With Suspected Heart Failure