Liposuction for surgical therapy of lipoedema: systematic review

Walter M, Gassner L
Record ID 32018001655
Authors' objectives: Lipoedema is a painful, chronic and progressive fat distribution disorder of the extremities. If conservative therapy does not result in sufficient improvement of symptoms, a surgical intervention, liposuction under tumescence anaesthesia, may be indicated. We investigated the clinical effectiveness and safety of liposuction for surgical therapy of lipoedema (stage I-III).
Authors' results and conclusions: The current evidence suggests that liposuctions lead to a significant pain reduction and improved health-related quality of life. However, the studies have several limitations. Overall, the quality of evidence for clinical effectiveness is not estimable and "very low" for safety outcomes.
Authors' recomendations: Inclusion in the Austrian benefit catalogue is currently not recommended. Robust comparative studies of liposuction for lipoedema are necessary in order to make a reliable statement regarding clinical effectiveness and safety.
Authors' methods: No comparative evidence could be identified. Six prospective and one additional retrospective single-arm before/after studies were evaluated.
Project Status: Completed
Year Published: 2021
URL for additional information:
English language abstract: An English language summary is available
Publication Type: Full HTA
Country: Austria
MeSH Terms
  • Lipedema
  • Lipectomy
  • Surgery, Plastic
  • Liposuction
  • lipoedema
  • fat distribution disorder
  • tumescent anaesthesia
  • systematic review
Organisation Name: Austrian Institute for Health Technology Assessment
Contact Address: Garnisongasse 7/20, A-1090 Vienna, Austria
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Contact Email:
Copyright: HTA Austria - AIHTA GmbH
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