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Welcome to the international HTA database

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Year Source Title
2016     NIHR Health Technology Assessment programme Clinical effectiveness and cost-effectiveness of use of therapeutic monitoring of tumour necrosis factor alpha (TNF-α) inhibitors [LISA-TRACKER® enzyme-linked immunosorbent assay (ELISA) kits, TNF-α-Blocker ELISA kits and Promonitor® ELISA kits] versus standard care in patients with Crohn's disease: systematic reviews and economic modelling
2017     NIHR Health Technology Assessment programme Adalimumab, etanercept and ustekinumab for treating plaque psoriasis in children and young people: systematic review and economic evaluation
2021     NIHR Health Technology Assessment programme A prognostic model, including quantitative fetal fibronectin, to predict preterm labour: the QUIDS meta-analysis and prospective cohort study
2023     NIHR Health Technology Assessment programme Antibiotics for lower respiratory tract infection in children presenting in primary care: ARTIC-PC RCT
1997     NIHR Health Technology Assessment programme The diagnosis, management, treatment and costs of prostate cancer in England and Wales
1998     NIHR Health Technology Assessment programme Postoperative analgesia and vomiting, with special reference to day-case surgery: a systematic review
2001     NIHR Health Technology Assessment programme Home treatment for mental health problems: a systematic review
2005     NIHR Health Technology Assessment programme The effectiveness of the Heidelberg Retina Tomograph and laser diagnostic glaucoma scanning system (GDx) in detecting and monitoring glaucoma
2014     NIHR Health Technology Assessment programme Structured, intensive education maximising engagement, motivation and long-term change for children and young people with diabetes: a cluster randomised controlled trial with integral process and economic evaluation the CASCADE study
2018     NIHR Health Technology Assessment programme AntiEpileptic drug Monitoring in PREgnancy (EMPiRE): a double-blind randomised trial on effectiveness and acceptability of monitoring strategies
2014     NIHR Health Technology Assessment programme Assessment of the feasibility and clinical value of further research to evaluate the management options for children with Down syndrome and otitis media with effusion: a feasibility study
2014     NIHR Health Technology Assessment programme A systematic review, psychometric analysis and qualitative assessment of generic preference-based measures of health in mental health populations and the estimation of mapping functions from widely specific measures
2015     NIHR Health Technology Assessment programme Diagnostic accuracy of the Thessaly test, standardised clinical history and other clinical examination tests (Apley's, McMurray's and joint line tenderness) for meniscal tears in comparison with magnetic resonance imaging diagnosis
2017     NIHR Health Technology Assessment programme A systematic review and economic evaluation of adalimumab and dexamethasone for treating non-infectious intermediate uveitis, posterior uveitis or panuveitis in adults
1997     NIHR Health Technology Assessment programme Implications of socio-cultural contexts for the ethics of clinical trials
1998     NIHR Health Technology Assessment programme Ethical issues in the design and conduct of randomised controlled trials: a review
2001     NIHR Health Technology Assessment programme Extended scope of nursing practice: a multicentre randomised controlled trial of appropriately trained nurses and pre-registration house officers in pre-operative assessment in elective general surgery
2015     NIHR Health Technology Assessment programme Strengthening And stretching for Rheumatoid Arthritis of the Hand (SARAH). A randomised controlled trial and economic evaluation
2016     NIHR Health Technology Assessment programme DiPALS: Diaphragm Pacing in patients with Amyotrophic Lateral Sclerosis - a randomised controlled trial
2015     NIHR Health Technology Assessment programme The management of Otitis Media with Effusion in children with cleft palate (mOMEnt): a feasibility study and economic evaluation
2012     NIHR Health Technology Assessment programme Bevacizumab in combination with capecitabine for the first-line treatment of metastatic breast cancer
2015     NIHR Health Technology Assessment programme The PAndemic INfluenza Triage in the Emergency Department (PAINTED) pilot cohort study
2014     NIHR Health Technology Assessment programme Allopurinol for the treatment of chronic kidney disease: a systematic review
2017     NIHR Health Technology Assessment programme Assessing the performance of methodological search filters to improve the efficiency of evidence information retrieval: five literature reviews and a qualitative study
1997     NIHR Health Technology Assessment programme Diagnosis, management and screening of early localised prostate cancer
1998     NIHR Health Technology Assessment programme Primary total hip replacement surgery: a systematic review of outcomes and modelling of cost-effectiveness associated with different prostheses
2001     NIHR Health Technology Assessment programme The measurement and monitoring of surgical adverse events
2017     NIHR Health Technology Assessment programme Clinical effectiveness and cost-effectiveness results from the randomised, Phase IIB trial in previously untreated patients with chronic lymphocytic leukaemia to compare fludarabine, cyclophosphamide and rituximab with fludarabine, cyclophosphamide, mitoxantrone and low-dose rituximab: the Attenuated dose Rituximab with ChemoTherapy In Chronic lymphocytic leukaemia (ARCTIC) trial
2019     NIHR Health Technology Assessment programme Prophylactic levofloxacin to prevent infections in newly diagnosed symptomatic myeloma: the TEAMM RCT
2014     NIHR Health Technology Assessment programme Systematic reviews of and integrated report on the quantitative, qualitative and economic evidence base for the management of obesity in men
2016     NIHR Health Technology Assessment programme A programme of studies including assessment of diagnostic accuracy of school hearing screening tests and a cost-effectiveness model of school entry hearing screening programmes
2014     NIHR Health Technology Assessment programme United Kingdom Oscillation Study: long-term outcomes of a randomised trial of two modes of neonatal ventilation
2017     NIHR Health Technology Assessment programme Facet-joint injections for non-specific low back pain: a feasibility RCT
1997     NIHR Health Technology Assessment programme Systematic review of outpatient services for chronic pain control
2014     NIHR Health Technology Assessment programme VenUS IV (Venous leg Ulcer Study IV) - compression hosiery compared with compression bandaging in the treatment of venous leg ulcers: a randomised controlled trial, mixed-treatment comparison and decision-analytic model
2017     NIHR Health Technology Assessment programme Clinical effectiveness and cost-effectiveness of a multifaceted podiatry intervention for falls prevention in older people: a multicentre cohort randomised controlled trial (the REducing Falls with ORthoses and a Multifaceted podiatry intervention trial)
2015     NIHR Health Technology Assessment programme Clinical effectiveness and cost-effectiveness of parenting interventions for children with severe attachment problems: a systematic review and meta-analysis
2021     NIHR Health Technology Assessment programme Preoperative intravenous iron for anaemia in elective major open abdominal surgery: the PREVENTT RCT
2014     NIHR Health Technology Assessment programme Death, Bereavement and randomised controlled trials (BRACELET): a methodological study of policy and practice in neonatal and paediatric intensive care trials
2017     NIHR Health Technology Assessment programme Self-management toolkit and delivery strategy for end-of-life pain: the mixed-methods feasibility study
2020     NIHR Health Technology Assessment programme Interventions for adults with a history of complex traumatic events: the INCiTE mixed-methods systematic review
2010     NIHR Health Technology Assessment programme Bevacizumab, sorafenib tosylate and sunitinib for renal cell carcinoma: a systematic review and economic evaluation
2014     NIHR Health Technology Assessment programme A randomised controlled trial and cost-effectiveness evaluation of booster interventions to sustain increases in physical activity in middle-aged adults in deprived urban neighbourhoods
2016     NIHR Health Technology Assessment programme A randomised placebo-controlled trial of oral and topical antibiotics for children with clinically infected eczema in the community: the ChildRen with Eczema, Antibiotic Management (CREAM) study
2015     NIHR Health Technology Assessment programme Systematic review, meta-analysis and economic modelling of molecular diagnostic tests for antibiotic resistance in tuberculosis
2020     NIHR Health Technology Assessment programme Thoracoscopy and talc poudrage compared with intercostal drainage and talc slurry infusion to manage malignant pleural effusion: the TAPPS RCT
2017     NIHR Health Technology Assessment programme Virtual chromoendoscopy for the real-time assessment of colorectal polyps in vivo: a systematic review and economic evaluation
1998     NIHR Health Technology Assessment programme Antenatal screening for Down's syndrome: a review
2010     NIHR Health Technology Assessment programme The clinical and cost effectiveness of testing for cytochrome P450 polymorphisms in patients treated with antipsychotics: a systematic review and economic evaluation
2014     NIHR Health Technology Assessment programme Rehabilitation aimed at improving outdoor mobility for people after stroke: a multi-centre randomised controlled study (the Getting out of the House Study)
2016     NIHR Health Technology Assessment programme A multicentre, randomised controlled trial comparing the clinical effectiveness and cost-effectiveness of early nutritional support via the parenteral versus the enteral route in critically ill patients (CALORIES)
2022     NIHR Health Technology Assessment programme Health-Related Quality of Life in two treatment pathways for newly diagnosed open angle glaucoma and ocular hypertension: an unmasked, multi-centre, randomised controlled trial of initial selective laser trabeculoplasty versus conventional medical therapy
2015     NIHR Health Technology Assessment programme Rapid detection of health-care-associated bloodstream infection in critical care using multipathogen real-time polymerase chain reaction technology: a diagnostic accuracy study and systematic review
2017     NIHR Health Technology Assessment programme Surveillance versus ablation for incidentally diagnosed small renal tumours: the SURAB feasibility RCT
2020     NIHR Health Technology Assessment programme Psychological interventions to improve self-management of type 1 and type 2 diabetes: a systematic review
2020     NIHR Health Technology Assessment programme Occupational advice to help people return to work following lower limb arthroplasty: the OPAL intervention mapping study
1998     NIHR Health Technology Assessment programme Screening for ovarian cancer: a systematic review
2014     NIHR Health Technology Assessment programme Prospective multicentre randomised, double-blind, equivalence study comparing clonidine and midazolam as intravenous sedative agents in critically ill children: the SLEEPS (Safety profiLe, Efficacy and Equivalence in Paediatric intensive care Sedation) study
2015     NIHR Health Technology Assessment programme Double-blind randomised controlled trial of percutaneous tibial nerve stimulation versus sham electrical stimulation in the treatment of faecal incontinence: CONtrol of Faecal Incontinence using Distal NeuromodulaTion (the CONFIDeNT trial)
2016     NIHR Health Technology Assessment programme A systematic review of the clinical effectiveness and cost-effectiveness of pharmacological and psychological interventions for the management of obsessive-compulsive disorder in children/adolescents and adults
1998     NIHR Health Technology Assessment programme Consensus development methods, and their use in clinical guideline development: a review
2005     NIHR Health Technology Assessment programme Improving the referral process for familial breast cancer genetic counselling: findings of three randomised controlled trials of two interventions
2010     NIHR Health Technology Assessment programme The effectiveness and cost-effectiveness of behavioural interventions for the prevention of sexually transmitted infections in young people aged 13-19: a systematic review and economic evaluation
2016     NIHR Health Technology Assessment programme Comparison Of iNfliximab and ciclosporin in Steroid Resistant Ulcerative Colitis: pragmatic randomised Trial and economic evaluation (CONSTRUCT)
2015     NIHR Health Technology Assessment programme An open randomised study of autoinflation in 4- to 11-year-old school children with otitis media with effusion in primary care
2018     NIHR Health Technology Assessment programme Positive behaviour support training for staff for treating challenging behaviour in people with intellectual disabilities: a cluster RCT
2020     NIHR Health Technology Assessment programme Denosumab, raloxifene, romosozumab and teriparatide to prevent osteoporotic fragility fractures: a systematic review and economic evaluation
2005     NIHR Health Technology Assessment programme Randomised evaluation of alternative electrosurgical modalities to treat bladder outflow obstruction in men with benign prostatic hyperplasia
2005     NIHR Health Technology Assessment programme The effectiveness and cost-effectiveness of pimecrolimus and tacrolimus for atopic eczema: a systematic review and economic evaluation
2010     NIHR Health Technology Assessment programme Effectiveness and cost-effectiveness of arthroscopic lavage in the treatment of osteoarthritis of the knee: a mixed methods study of the feasibility of conducting a surgical placebo-controlled trial (the KORAL study)
2016     NIHR Health Technology Assessment programme PROMISE: first-trimester progesterone therapy in women with a history of unexplained recurrent miscarriages - a randomised, double-blind, placebo-controlled, international multicentre trial and economic evaluation
2016     NIHR Health Technology Assessment programme The feasibility of determining the effectiveness and cost-effectiveness of medication organisation devices compared with usual care for older people in a community setting: systematic review, stakeholder focus groups and feasibility randomised controlled trial
2018     NIHR Health Technology Assessment programme The UK EndoVascular Aneurysm Repair (EVAR) randomised controlled trials: long-term follow-up and cost-effectiveness analysis
2014     NIHR Health Technology Assessment programme KRAS mutation testing of tumours in adults with metastatic colorectal cancer: a systematic review and cost-effectiveness analysis
2003     NIHR Health Technology Assessment programme Redesigning postnatal care: a randomised controlled trial of protocol-based midwifery-led care focused on individual women's physical and psychological health needs
2005     NIHR Health Technology Assessment programme Outcomes of electrically stimulated gracilis neosphincter surgery
2010     NIHR Health Technology Assessment programme Weighting and valuing quality-adjusted life-years using stated preference methods: preliminary results from the Social Value of a QALY Project
2015     NIHR Health Technology Assessment programme A multicentre randomised controlled trial and economic evaluation of continuous positive airway pressure for the treatment of obstructive sleep apnoea syndrome in older people: PREDICT
2017     NIHR Health Technology Assessment programme Development and validation of Prediction models for Risks of complications in Early-onset Pre-eclampsia (PREP): a prospective cohort study
2020     NIHR Health Technology Assessment programme Silver-impregnated, antibiotic-impregnated or non-impregnated ventriculoperitoneal shunts to prevent shunt infection: the BASICS three-arm RCT
2003     NIHR Health Technology Assessment programme Estimating implied rates of discount in healthcare decision-making
2005     NIHR Health Technology Assessment programme Cost-effectiveness of alternative strategies for the initial medical management of non-ST elevation acute coronary syndrome: systematic review and decision-analytical modelling
2010     NIHR Health Technology Assessment programme Systematic review of the clinical effectiveness and cost-effectiveness of photodynamic diagnosis and urine biomarkers (FISH, ImmunoCyt, NMP22) and cytology for the detection and follow-up of bladder cancer
2016     NIHR Health Technology Assessment programme A cost-effectiveness modelling study of strategies to reduce risk of infection following primary hip replacement based on a systematic review
2015     NIHR Health Technology Assessment programme Initiating change locally in bullying and aggression through the school environment (INCLUSIVE): a pilot randomised controlled trial
2015     NIHR Health Technology Assessment programme Blinded randomised controlled trial of low-dose Adjuvant Steroids in Adults admitted to hospital with Pandemic influenza (ASAP): a trial 'in hibernation', ready for rapid activation
1999     NIHR Health Technology Assessment programme Informed decision making: an annotated bibliography and systematic review
2003     NIHR Health Technology Assessment programme Systematic review of isolation policies in the hospital management of methicillin-resistant Staphylococcus aureus: a review of the literature with epidemiological and economic modelling
2005     NIHR Health Technology Assessment programme Indirect comparisons of competing interventions
2007     NIHR Health Technology Assessment programme Systematic review of the links between human resource management practices and performance
2015     NIHR Health Technology Assessment programme Screening for psychological and mental health difficulties in young people who offend: a systematic review and decision model
2016     NIHR Health Technology Assessment programme The feasibility of a randomised controlled trial of physiotherapy for adults with joint hypermobility syndrome
2014     NIHR Health Technology Assessment programme Clinical effectiveness of interventions for treatment-resistant anxiety in older people: a systematic review
2003     NIHR Health Technology Assessment programme Treatments for spasticity and pain in multiple sclerosis: a systematic review
2005     NIHR Health Technology Assessment programme Systematic review on urine albumin testing for early detection of diabetic complications
2010     NIHR Health Technology Assessment programme The clinical effectiveness and cost-effectiveness of topotecan for small cell lung cancer: a systematic review and economic evaluation
2015     NIHR Health Technology Assessment programme A randomised controlled trial and cost-effectiveness analysis of high-frequency oscillatory ventilation against conventional artificial ventilation for adults with acute respiratory distress syndrome. The OSCAR (OSCillation in ARDS) study
2014     NIHR Health Technology Assessment programme A systematic review of the effectiveness and cost-effectiveness of sensory, psychological and behavioural interventions for managing agitation in older adults with dementia
2017     NIHR Health Technology Assessment programme CollAborative care for Screen-Positive EldeRs with major depression (CASPER plus): a multicentred randomised controlled trial of clinical effectiveness and cost-effectiveness
2015     NIHR Health Technology Assessment programme Clinical trial metadata: defining and extracting metadata on the design, conduct, results and costs of 125 randomised clinical trials funded by the National Institute for Health Research Health Technology Assessment programme