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Year Source Title
2021 Scottish Medicines Consortium (SMC) Brentuximab vedotin in combination with cyclophosphamide, doxorubicin and prednisone (CHP) is indicated for adult patients with previously untreated systemic anaplastic large cell lymphoma (sALCL)
2021 Scottish Medicines Consortium (SMC) Melatonin (Slenyto) for the treatment of insomnia in children and adolescents aged 2-18 with autism spectrum disorder (ASD) and / or Smith-Magenis syndrome, where sleep hygiene measures have been insufficient
2021 Scottish Medicines Consortium (SMC) Fostamatinib treatment of chronic immune thrombocytopenia in adult patients who are refractory to other treatments
2021 Scottish Medicines Consortium (SMC) Entrectinib for the treatment of patients with ROS1-positive, advanced non-small-cell lung cancer (NSCLC) not previously treated with ROS-1 inhibitors
2021 Institut national d'excellence en sante et en services sociaux (INESSS) [Report: advisability of using molecular tests to clarify the diagnosis of thyroid nodules with indeterminate cytology]
2021 Institut national d'excellence en sante et en services sociaux (INESSS) [Report: noninvasive fetal RhD genotyping using maternal plasma]
2021 Institut national d'excellence en sante et en services sociaux (INESSS) [State of knowledge: artificial intelligence-assisted diabetic retinopathy tele-screening]
2021 NIHR Health Technology Assessment programme Enzyme-linked immunosorbent assays for monitoring TNF-alpha inhibitors and antibody levels in people with rheumatoid arthritis: a systematic review and economic evaluation
2021 Norwegian Institute of Public Health (NIPH) Hydrogel rectal spacer SpaceOAR in prostate cancer radiation therapy - health economic evaluation
2021 Norwegian Institute of Public Health (NIPH) Transcatheter aortic valve implantation (TAVI) versus surgical aortic valve replacement (SAVR) for patients with severe aortic stenosis and low surgical risk and across surgical risk groups: a health technology assessment
2021 NIHR Health Technology Assessment programme Cognitive–behavioural therapy for a variety of conditions: an overview of systematic reviews and panoramic meta-analysis
2021 NIHR Health Technology Assessment programme Patch augmentation surgery for rotator cuff repair: the PARCS mixed-methods feasibility study
2021 NIHR Health Services and Delivery Research programme Respite care and short breaks for young adults aged 18–40 with complex health-care needs: mixed-methods systematic review and conceptual framework development
2021 Norwegian Institute of Public Health (NIPH) Surgery for carpal tunnel syndrome: a health technology assessment
2021 NIHR Health Technology Assessment programme Universal late pregnancy ultrasound screening to predict adverse outcomes in nulliparous women: a systematic review and cost-effectiveness analysis
2021 Norwegian Institute of Public Health (NIPH) Evaluation of tests for FLT3 mutations in acute myeloid leukaemia (AML)
2021 Norwegian Institute of Public Health (NIPH) Subacromial decompression surgery for impingement syndrome: rapid health technology assessment
2021 Institut national d'excellence en sante et en services sociaux (INESSS) [Guidelines and standards: initiating pharmacological treatment for clearing an occluded central venous access device (CVAD)]
2021 Norwegian Institute of Public Health (NIPH) [Intravenous immunoglobulin treatment in children with PANS/PANDAS conditions]
2021 Institut national d'excellence en sante et en services sociaux (INESSS) [Report: Hemlibra (emicizumab) – Hemophilia A without inhibitor (re evaluation)]
2021 Institut national d'excellence en sante et en services sociaux (INESSS) [Lyme disease and persistent symptoms: a look at the current knowledge and recommendations for improving management]
2021 Institut national d'excellence en sante et en services sociaux (INESSS) [Report: clinical utility of the different Western blot antigen profiles in the context of disseminated Lyme disease]
2021 Institut national d'excellence en sante et en services sociaux (INESSS) [State of knowledge: chronic” Lyme disease: current state of knowledge and overview of the different perspectives]
2021 NIHR Health Technology Assessment programme Prognostic tools for identification of high risk in people with Crohn’s disease: systematic review and cost-effectiveness study
2021 Scottish Medicines Consortium (SMC) Afamelanotide (Scenesse) for prevention of photoxicity in adult patients with erythropoietic protoporphyria (EPP)
2021 Scottish Medicines Consortium (SMC) Upadacitinib for the treatment of moderate to severe active rheumatoid arthritis in adult patients who have responded inadequately to, or who are intolerant to one or more disease-modifying anti-rheumatic drugs (DMARDs)
2021 Scottish Medicines Consortium (SMC) Ravulizumab for the treatment of adult patients with paroxysmal nocturnal haemoglobinuria (PNH): in patients with haemolysis with clinical symptom(s) indicative of high disease activity; in patients who are clinically stable after having been treated with eculizumab for at least the past 6 months
2021 Scottish Medicines Consortium (SMC) Ozanimod for adult patients with relapsing remitting multiple sclerosis
2021 Scottish Medicines Consortium (SMC) Entrectinib as monotherapy for the treatment of adult and paediatric patients 12 years of age and older with solid tumours expressing a neurotrophic tyrosine receptor kinase (NTRK) gene fusion: who have a disease that is locally advanced, metastatic or where surgical resection is likely to result in severe morbidity; and who have not received a prior NTRK inhibitor; who have no satisfactory treatment options
2021 Scottish Medicines Consortium (SMC) Onasemnogene abeparvovec treatment of patients with 5q spinal muscular atrophy (SMA) with a bi-allelic mutation in the SMN1 gene and a clinical diagnosis of SMA type 1, or patients with 5q SMA with a bi-allelic mutation in the SMN1 gene and up to 3 copies of the SMN2 gene
2021 Institut national d'excellence en sante et en services sociaux (INESSS) [Report: validation of the management framework for a nonspecific human immunoglobulin shortage]
2021 Institut national d'excellence en sante et en services sociaux (INESSS) [Guidelines and standards: standards for the management of acute ST-segment elevation myocardial infarction (STEMI) in Québec (update of April 2021)]
2021 Swedish Agency for Health Technology Assessment and Assessment of Social Services (SBU) [Internet-based psychological treatment for anxiety and depression]
2021 Scottish Health Technologies Group (SHTG) NHSScotland COPD Support Service: remote and self-management of high-risk patients with COPD using a web app and machine learning predictive modelling
2021 Swedish Agency for Health Technology Assessment and Assessment of Social Services (SBU) [Diagnostics and treatment of provoked vestibulodynia]
2021 Swedish Agency for Health Technology Assessment and Assessment of Social Services (SBU) [Continuity of care]
2021 Swedish Agency for Health Technology Assessment and Assessment of Social Services (SBU) [Lipoedema – diagnosis, treatment, and experiences]
2021 Swedish Agency for Health Technology Assessment and Assessment of Social Services (SBU) [Multimodal and interdisciplinary interventions for long term pain]
2021 Swedish Agency for Health Technology Assessment and Assessment of Social Services (SBU) [Caesarean section on maternal request]
2021 Swedish Agency for Health Technology Assessment and Assessment of Social Services (SBU) [Treatment and rehabilitation of people with fibromyalgia]
2021 Swedish Agency for Health Technology Assessment and Assessment of Social Services (SBU) [Programs for preventing suicide and suicide attempt in children]
2021 Scientific Advice Unit, avalia-t; The Galician Health Knowledge Agency (ACIS) [Newborn screening for classic congenital adrenal hyperplasia. Update and assessment of regional programs]
2021 Institut national d'excellence en sante et en services sociaux (INESSS) [Report: optimal use of immunoglobulins in rheumatology. Report in support of the optimal use guide English summary]
2021 Institut national d'excellence en sante et en services sociaux (INESSS) [State of knowledge: efficacy and safety of immunoglobulins in rheumatology. Systematic review report]
2021 Austrian Institute for Health Technology Assessment (AIHTA) Robotics and functional electrical stimulation for stroke rehabilitation: systematic review
2021 Austrian Institute for Health Technology Assessment (AIHTA) [Parent-Child-Pass Update 2020/21 – Screenings for mental health, nutrition and social competence]
2021 Penn Medicine Center for Evidence-based Practice (CEP) Ambulatory blood glucose checks
2021 Penn Medicine Center for Evidence-based Practice (CEP) Prevention of opioid-induced respiratory depression (OIRD) in hospital care
2021 Penn Medicine Center for Evidence-based Practice (CEP) Fall prevention in ambulatory care facilities
2021 Penn Medicine Center for Evidence-based Practice (CEP) Triaging COVID-19 in the emergency department
2021 Penn Medicine Center for Evidence-based Practice (CEP) Critical value thresholds
2021 Norwegian Institute of Public Health (NIPH) Minimally invasive glaucoma surgery (MIGS) for individuals with glaucoma. A health technology assessment
2021 Institut national d'excellence en sante et en services sociaux (INESSS) [Guidelines and standards: initiating diagnostic measures in a person with signs and symptoms suggestive of a urinary tract infection (cystitis or pyelonephritis) and initiating first-line pharmacological treatment for cystitis in an adult with functional autonomy decline]
2021 Institut national d'excellence en sante et en services sociaux (INESSS) [Guidelines and standards: urinary catheter placement in an adult with functional autonomy decline presenting with symptoms suggestive of acute urinary retention]
2021 Institut national d'excellence en sante et en services sociaux (INESSS) [Guidelines and standards: initiating blood work for the purpose of evaluating diagnosed or suspected alcohol use disorder]
2021 Institut national d'excellence en sante et en services sociaux (INESSS) [Guidelines and standards: initiating pharmacotherapy for relapse prevention in a person with alcohol use disorder]
2021 Institut national d'excellence en sante et en services sociaux (INESSS) [State of knowledge: efficacy and safety of pharmacological treatments for alcohol withdrawal and relapse prevention]
2021 Institut national d'excellence en sante et en services sociaux (INESSS) [Guidelines and standards: administration of benzodiazepines or gabapentin prescribed via an individual prescription for alcohol withdrawal]
2021 Institut national d'excellence en sante et en services sociaux (INESSS) [Guidelines and standards: assessment and risk management of severe neurological complications following mild traumatic brain injury]
2021 European Network for Health Technology Assessment (EUnetHTA) Comparative effectiveness of surgical techniques and devices for the treatment of benign prostatic hyperplasia
2021 European Network for Health Technology Assessment (EUnetHTA) Convalescent plasma therapy for the treatment of COVID-19
2021 European Network for Health Technology Assessment (EUnetHTA) Tocilizumab for the treatment of COVID-19
2021 European Network for Health Technology Assessment (EUnetHTA) Camostat for the treatment of COVID-19
2021 European Network for Health Technology Assessment (EUnetHTA) Nafamostat for the treatment of COVID-19
2021 European Network for Health Technology Assessment (EUnetHTA) Solnatide for the treatment of COVID-19
2021 European Network for Health Technology Assessment (EUnetHTA) Anakinra for the treatment of COVID-19
2021 European Network for Health Technology Assessment (EUnetHTA) APN01 for the treatment of COVID-19
2021 European Network for Health Technology Assessment (EUnetHTA) Darunavir for the treatment of COVID-19
2021 European Network for Health Technology Assessment (EUnetHTA) Favipiravir for the treatment of COVID-19
2021 European Network for Health Technology Assessment (EUnetHTA) Sarilumab for the treatment of COVID-19
2021 European Network for Health Technology Assessment (EUnetHTA) Interferon (IFN) and Novaferon (NOVA) for the treatment of COVID-19
2021 European Network for Health Technology Assessment (EUnetHTA) Gimsilumab for the treatment of COVID-19
2021 European Network for Health Technology Assessment (EUnetHTA) Canakinumab for the treatment of COVID-19
2021 European Network for Health Technology Assessment (EUnetHTA) Casirivimab and imdevimab (REGN-COV2) for the treatment of COVID-19
2021 European Network for Health Technology Assessment (EUnetHTA) Bamlanivimab for the treatment of COVID-19
2021 European Network for Health Technology Assessment (EUnetHTA) Baricitinib for the treatment of COVID-19
2021 European Network for Health Technology Assessment (EUnetHTA) Molnupiravir for the treatment of COVID-19
2021 European Network for Health Technology Assessment (EUnetHTA) High-dose vitamin D for the treatment of COVID-19
2021 European Network for Health Technology Assessment (EUnetHTA) Mavrilimumab for the treatment of COVID-19
2021 European Network for Health Technology Assessment (EUnetHTA) Ivermectin for the treatment of COVID-19
2021 European Network for Health Technology Assessment (EUnetHTA) Aspirin for the treatment of COVID-19
2021 Swiss Federal Office of Public Health (FOPH) Corneal collagen crosslinking for the treatment of progressive keratoconus
2021 Swiss Federal Office of Public Health (FOPH) Infliximab reference product versus biosimilar for the treatment of rheumatoid arthritis
2021 Swiss Federal Office of Public Health (FOPH) Medical cannabis for treating various symptoms in Switzerland
2021 Swiss Federal Office of Public Health (FOPH) Palbociclib (Ibrance®), ribociclib (Kisqali®) and abemaciclib (Verzenios®) for the treatment of hormone receptor (HR)-positive, human epidermal growth factor (HER2)-negative advanced breast cancer
2021 Swiss Federal Office of Public Health (FOPH) Subacromial decompression as a primary/isolated intervention to treat subacromial pain
2021 Swiss Federal Office of Public Health (FOPH) The treatment of hypercholesterolaemia and mixed/combined hyperlipidaemia with ezetimibe-containing medicines
2021 Swedish Agency for Health Technology Assessment and Assessment of Social Services (SBU) [Screening for common mental disorders during pregnancy and for traumatic experiences after delivery]
2021 Norwegian Institute of Public Health (NIPH) [Liposuction (lipectomy) for the treatment of fat accumulation caused by chronic lymphoedema]
2021 Penn Medicine Center for Evidence-based Practice (CEP) COVID-19: mandatory vaccination
2021 NIHR Health Services and Delivery Research programme Hospital-based specialist palliative care compared with usual care for adults with advanced illness and their caregivers: a systematic review
2021 Penn Medicine Center for Evidence-based Practice (CEP) COVID-19: thrombotic adverse events with adenovirus vaccines
2021 NIHR Health Technology Assessment programme High-sensitivity troponin assays for early rule-out of acute myocardial infarction in people with acute chest pain: a systematic review and economic evaluation
2021 Norwegian Institute of Public Health (NIPH) [Natalizumab subcutaneous for the treatment of relapsing remitting multiple sclerosis: a rapid health technology assessment - health economic evaluation]
2021 Norwegian Institute of Public Health (NIPH) [Ofatumumab for the treatment of relapsing remitting multiple sclerosis: a rapid health technology assessment – health economic evaluation]
2021 NIHR Health Technology Assessment programme Modelling tool to support decision-making in the NHS Health Check programme: workshops, systematic review and co-production with users
2021 Centre intégré universitaire de santé et de services sociaux de la Capitale-Nationale (CIUSSS) [Specific rehabilitation interventions for physical impairment to avoid chronification of non-specific back pain in adults]
2021 Penn Medicine Center for Evidence-based Practice (CEP) Opioids for vaso-occlusive crisis in pregnant patients
2021 Penn Medicine Center for Evidence-based Practice (CEP) COVID-19: vaccination for women who are pregnant or lactating
2021 Penn Medicine Center for Evidence-based Practice (CEP) COVID-19: management of vaccine-associated thrombotic syndromes