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Year Source Title
2021     NIHR Health Technology Assessment programme DISC: Dupuytren's Interventions Surgery vs. Collagenase. A pragmatic multi-centre randomised controlled non-inferiority, cost effectiveness trial comparing injections of collagenase into the cord to surgical correction in the treatment of moderate Dupuytren's contracture in adult patients
2021     Norwegian Institute of Public Health (NIPH) Subacromial decompression surgery for impingement syndrome: rapid health technology assessment
2021     Institute for Clinical Effectiveness and Health Policy (IECS) [Non-invasive respiratory support in Covid-19 patients]
2021     Institute for Clinical Effectiveness and Health Policy (IECS) [Brolucizumab in neovascular age-related macular degeneration]
2021     Institute for Clinical Effectiveness and Health Policy (IECS) [COVID-19: follow-up after an acute episode]
2021     Institute for Clinical Effectiveness and Health Policy (IECS) [Microperimetry in retinopathies]
2021     NIHR Health Technology Assessment programme Assistive technology and telecare to maintain independent living at home for people with dementia: the ATTILA RCT
2021     Institute for Clinical Effectiveness and Health Policy (IECS) [Cardiopulmonary resuscitation in COVID-19 patients]
2021     Scientific Advice Unit, avalia-t; The Galician Health Knowledge Agency (ACIS) [Clinical Practice Guideline on adult's palliative care]
2021     Institute for Clinical Effectiveness and Health Policy (IECS) [Patisiran and inotersen in hereditary transthyretin-mediated amyloidosis]
2021     NIHR Health Technology Assessment programme Impact of multiparametric MRI on staging and management of patients with suspected or confirmed ovarian cancer Short title: MR in Ovarian Cancer (MROC study)
2021     Institute for Clinical Effectiveness and Health Policy (IECS) [Whole-exome sequencing in patients with neurological disorders]
2021     NIHR Health Services and Delivery Research programme Pay More Attention: a national mixed methods study to identify the barriers and facilitators to ensuring equal access to high quality hospital care and services for children and young people with learning disability and their families
2021     NIHR Health Technology Assessment programme UK Cohort study to Investigate the prevention of Parastomal Hernia (CIPHER)
2021     Institute for Clinical Effectiveness and Health Policy (IECS) [Transcatheter aortic valve implantation in severe aortic stenosis]
2021     Institut national d'excellence en sante et en services sociaux (INESSS) [Guidelines and standards: initiating pharmacological treatment for clearing an occluded central venous access device (CVAD)]
2021     Institute for Clinical Effectiveness and Health Policy (IECS) [Swallowable gastric balloon in obesity]
2021     Institute for Clinical Effectiveness and Health Policy (IECS) [Whole exome sequencing in patients with intellectual disability and/or autism spectrum disorder]
2021     Institute for Clinical Effectiveness and Health Policy (IECS) [Extracranial stereotactic body radiotherapy in oligometastasis]
2021     Institute for Clinical Effectiveness and Health Policy (IECS) [Whole exome sequencing in epileptic encephalopathies]
2021     Institute for Clinical Effectiveness and Health Policy (IECS) [Baricitinib in COVID-19 patients]
2021     Institute for Clinical Effectiveness and Health Policy (IECS) [Edaravone in patients with amyotrophic lateral sclerosis]
2021     Norwegian Institute of Public Health (NIPH) [Intravenous immunoglobulin treatment in children with PANS/PANDAS conditions]
2021     Institut national d'excellence en sante et en services sociaux (INESSS) [Report: Hemlibra(emicizumab) – Hemophilia A without inhibitor (re evaluation)]
2021     Institut national d'excellence en sante et en services sociaux (INESSS) [Lyme disease and persistent symptoms: a look at the current knowledge and recommendations for improving management]
2021     Institut national d'excellence en sante et en services sociaux (INESSS) [Report: clinical utility of the different Western blot antigen profiles in the context of disseminated Lyme disease]
2021     Institut national d'excellence en sante et en services sociaux (INESSS) [State of knowledge: chronic” Lyme disease: current state of knowledge and overview of the different perspectives]
2021     NIHR Health Technology Assessment programme Prognostic tools for identification of high risk in people with Crohn’s disease: systematic review and cost-effectiveness study
2021     Scottish Medicines Consortium (SMC) Afamelanotide (Scenesse) for prevention of photoxicity in adult patients with erythropoietic protoporphyria (EPP)
2021     NIHR Health Technology Assessment programme A multicentre randomised controlled trial of induced endometrial trauma in women undergoing first time In Vitro Fertilisation (IVF)
2021     Scottish Medicines Consortium (SMC) Upadacitinib for the treatment of moderate to severe active rheumatoid arthritis in adult patients who have responded inadequately to, or who are intolerant to one or more disease-modifying anti-rheumatic drugs (DMARDs)
2021     NIHR Health Technology Assessment programme Risks and benefits of bisphosphonate use in patients with chronic kidney disease: a population-based cohort study
2021     Scottish Medicines Consortium (SMC) Ravulizumab for the treatment of adult patients with paroxysmal nocturnal haemoglobinuria (PNH): in patients with haemolysis with clinical symptom(s) indicative of high disease activity; in patients who are clinically stable after having been treated with eculizumab for at least the past 6 months
2021     NIHR Health Technology Assessment programme Facilitating the return to work of NHS staff with common mental health disorders: a feasibility study
2021     Scottish Medicines Consortium (SMC) Ozanimod for adult patients with relapsing remitting multiple sclerosis
2021     NIHR Health Technology Assessment programme QUIDS Quantitative fibronectin to help decision-making in women with symptoms of preterm labour
2021     NIHR Health Technology Assessment programme The Invasive Dentistry Endocarditis Association Study: the IDEA Study
2021     Scottish Medicines Consortium (SMC) Entrectinib as monotherapy for the treatment of adult and paediatric patients 12 years of age and older with solid tumours expressing a neurotrophic tyrosine receptor kinase (NTRK) gene fusion: who have a disease that is locally advanced, metastatic or where surgical resection is likely to result in severe morbidity; and who have not received a prior NTRK inhibitor; who have no satisfactory treatment options
2021     NIHR Health Technology Assessment programme Palliative radiotherapy combined with stent insertion to reduce recurrent dysphagia in oesophageal cancer patients: the ROCS RCT
2021     NIHR Health Technology Assessment programme Co-trimoxazole to reduce mortality, transplant, or unplanned hospitalisation in people with moderate to very severe idiopathic pulmonary fibrosis: the EME-TIPAC RCT
2021     Scottish Medicines Consortium (SMC) Onasemnogene abeparvovec treatment of patients with 5q spinal muscular atrophy (SMA) with a bi-allelic mutation in the SMN1 gene and a clinical diagnosis of SMA type 1, or patients with 5q SMA with a bi-allelic mutation in the SMN1 gene and up to 3 copies of the SMN2 gene
2021     Institut national d'excellence en sante et en services sociaux (INESSS) [Report: validation of the management framework for a nonspecific human immunoglobulin shortage]
2021     Institut national d'excellence en sante et en services sociaux (INESSS) [Guidelines and standards: standards for the management of acute ST-segment elevation myocardial infarction (STEMI) in Québec (update of April 2021)]
2021     Swedish Agency for Health Technology Assessment and Assessment of Social Services (SBU) Internet-based psychological treatment for anxiety and depression (an update)
2021     Scottish Health Technologies Group (SHTG) NHSScotland COPD Support Service: remote and self-management of high-risk patients with COPD using a web app and machine learning predictive modelling
2021     Swedish Agency for Health Technology Assessment and Assessment of Social Services (SBU) Occupational exposure and upper extremity pain
2021     Swedish Agency for Health Technology Assessment and Assessment of Social Services (SBU) Diagnostics and treatment of provoked vestibulodynia
2021     Swedish Agency for Health Technology Assessment and Assessment of Social Services (SBU) Continuity of care
2021     Institute for Clinical Effectiveness and Health Policy (IECS) [Ketoanalogs in association with high protein diet in chronic kidney failure]
2021     Swedish Agency for Health Technology Assessment and Assessment of Social Services (SBU) Dietary treatment of diabetes
2021     Institute for Clinical Effectiveness and Health Policy (IECS) [Precice® motorized intramedullary nail system for limb-length discrepancy]
2021     Swedish Agency for Health Technology Assessment and Assessment of Social Services (SBU) Lipoedema – diagnosis, treatment, and experiences
2021     Institute for Clinical Effectiveness and Health Policy (IECS) [Direct-acting oral anticoagulants for postoperative thrombosis prophylaxis]
2021     Swedish Agency for Health Technology Assessment and Assessment of Social Services (SBU) Complex interventions for chronic pain
2021     Institute for Clinical Effectiveness and Health Policy (IECS) [Genetic testing for lynch syndrome in colorectal cancer and family members]
2021     Swedish Agency for Health Technology Assessment and Assessment of Social Services (SBU) Childbirth with Caesarean section on the pregnant woman's request - advantages and disadvantages for the mother and child
2021     NIHR Public Health Research (PHR) programme School-based interventions to prevent anxiety, depression and conduct disorder in children and young people: a systematic review and network meta-analysis
2021     Center for Evidence-based Practice (CEP) Opioid pain assessment
2021     Center for Evidence-based Practice (CEP) Effectiveness of intra-operative antimicrobial irrigation to prevent surgical site infection in clean surgeries
2021     Swedish Agency for Health Technology Assessment and Assessment of Social Services (SBU) Treatment and rehabilitation of people with fibromyalgia
2021     Institut national d'excellence en sante et en services sociaux (INESSS) [State of practice: long-term left ventricular assist devices, real-world evolving portrait of use and outcomes in Québec from 2010 to 2017]
2021     Swedish Agency for Health Technology Assessment and Assessment of Social Services (SBU) Programs for prevention of suicide and suicidal attempts in children and adolescents
2021     Institut national d'excellence en sante et en services sociaux (INESSS) [Guidelines and standards: alcohol withdrawal and relapse prevention]
2021     NIHR Health Technology Assessment programme The Arabin pessary to prevent preterm birth in women with a twin pregnancy and a short cervix: the STOPPIT 2 RCT
2021     Institut national d'excellence en sante et en services sociaux (INESSS) [Report: relevance of using mpMRI for the diagnostic investigation of prostate cancer - mpMRI and prostate cancer diagnosis]
2021     NIHR Public Health Research (PHR) programme A cluster randomised controlled trial to evaluate the effectiveness and cost-effectiveness of the GoActive programme to increase physical activity among 13-14 year-old adolescents
2021     Scientific Advice Unit, avalia-t; The Galician Health Knowledge Agency (ACIS) [Newborn screening for classic congenital adrenal hyperplasia. Update and assessment of regional programs]
2021     Institut national d'excellence en sante et en services sociaux (INESSS) [Report: optimal use of immunoglobulins in rheumatology. Report in support of the optimal use guide English summary]
2021     NIHR Health Technology Assessment programme Radiation versus Observation following surgical resection of Atypical Meningioma: a randomised controlled trial (The ROAM trial)
2021     Institut national d'excellence en sante et en services sociaux (INESSS) [State of knowledge: efficacy and safety of immunoglobulins in rheumatology. Systematic review report]
2021     Agency for Care Effectiveness (ACE) Rituximab for treating non-Hodgkin's lymphoma and chronic lymphocytic leukaemia
2021     Austrian Institute for Health Technology Assessment (AIHTA) Robotics and functional electrical stimulation for stroke rehabilitation: systematic review
2021     Austrian Institute for Health Technology Assessment (AIHTA) [Parent-Child-Pass Update 2020/21 – Screenings for mental health, nutrition and social competence]
2021     Center for Evidence-based Practice (CEP) Ambulatory blood glucose checks
2021     Agency for Care Effectiveness (ACE) Tenofovir alafenamide for treating chronic hepatitis B infection
2021     NIHR Public Health Research (PHR) programme A randomised controlled trial and economic evaluation of a community-based physical activity intervention to prevent mobility-related disability for retired older people. The REACT (REtirement in ACTion) study
2021     Center for Evidence-based Practice (CEP) Prevention of opioid-induced respiratory depression (OIRD) in hospital care
2021     Agency for Care Effectiveness (ACE) Metformin extended release for treating type 2 diabetes mellitus
2021     NIHR Health Technology Assessment programme PRODIGY: Prevention and treatment of long term social disability amongst young people with emerging severe mental illness: A randomised controlled trial
2021     Center for Evidence-based Practice (CEP) Fall prevention in ambulatory care facilities
2021     Agency for Care Effectiveness (ACE) Guselkumab, ixekizumab and secukinumab for treating chronic plaque psoriasis
2021     Center for Evidence-based Practice (CEP) Triaging COVID-19 in the emergency department
2021     Agency for Care Effectiveness (ACE) Ixekizumab and secukinumab for treating active psoriatic arthritis
2021     Center for Evidence-based Practice (CEP) Critical value thresholds
2021     Agency for Care Effectiveness (ACE) Dacomitinib for treating EGFR mutation-positive non-small-cell lung cancer
2021     NIHR Health Services and Delivery Research programme The TRECA study: TRials Engagement in Children and Adolescents
2021     Health Technology Wales (HTW) Corneal crosslinking to treat adults and children with keratoconus
2021     Agency for Care Effectiveness (ACE) Ixekizumab and secukinumab for treating active ankylosing spondylitis
2021     Health Technology Wales (HTW) Freestyle Libre flash glucose monitoring for the management of diabetes
2021     The Federal Joint Committee (G-BA) [Pharmaceutical Directive/Annex XII: Bulevirtide (chronic hepatitis delta virus (HDV) infection)]
2021     NIHR Health Technology Assessment programme Estimating the benefits and harms of Z-drugs for people with dementia and sleep disorders
2021     The Federal Joint Committee (G-BA) [Pharmaceuticals Directive/Annex XII: Burosumab (new therapeutic indication: X-linked hypophosphataemia, ≥ 18 years)]
2021     The Federal Joint Committee (G-BA) [Pharmaceutical Directive/Annex XII: Afamelanotide (Reassessment after the deadline: Phototoxicity in erythropoietic protoporphyria (EPP))]
2021     NIHR Health Technology Assessment programme ROCkeTS - Refining Ovarian Cancer Test Accuracy Scores
2021     NIHR Health Technology Assessment programme A randomised pragmatic trial comparing the clinical and cost effectiveness of lithium and quetiapine augmentation in treatment resistant depression.
2021     NIHR Health Technology Assessment programme Preventing enduring behavioural problems in young children through early psychological intervention: Healthy Start, Happy Start
2021     NIHR Health Technology Assessment programme A multi-centre cluster randomised controlled trial to evaluate the Guide to Action Care Home fall prevention programme in care homes for older people (FinCH)
2021     NIHR Health Technology Assessment programme Investigating the effectiveness and cost effectiveness of using FITNET to treat paediatric CFS/ME in the UK
2021     Norwegian Institute of Public Health (NIPH) Minimally invasive glaucoma surgery (MIGS) for individuals with glaucoma. A health technology assessment
2021     NIHR Health Technology Assessment programme Statin Web-based Investigation of Side Effects Trial (Statin WISE Trial)