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Year Source Title
2011     NIHR Horizon Scanning Centre (NIHR HSC) Everolimus (Votubia) for angiomyolipoma associated with tuberous sclerosis complex or sporadic lymphangioleiomyomatosis - first line or post surgery
2014     NIHR Horizon Scanning Centre (NIHR HSC) Minicare H-2000 remote monitoring system for patients undergoing chemotherapy
2007     NIHR Horizon Scanning Centre (NIHR HSC) Generex Oral-lyn (buccal insulin) for diabetes mellitus
2008     NIHR Horizon Scanning Centre (NIHR HSC) Aripiprazole (Abilify) for schizophrenia in children and adolescents
2011     NIHR Horizon Scanning Centre (NIHR HSC) Girentuximab (Rencarex) for renal cell carcinoma
2014     NIHR Horizon Scanning Centre (NIHR HSC) Ciclosporin (CicloMulsion) for reperfusion injury prevention prior to percutaneous coronary intervention for ST-segment elevation acute myocardial infarction
2007     NIHR Horizon Scanning Centre (NIHR HSC) Pregabalin (Lyrica) for fibromyalgia
2008     NIHR Horizon Scanning Centre (NIHR HSC) Aripiprazole (Abilify) for children and adolescents with bipolar disorder
2011     NIHR Horizon Scanning Centre (NIHR HSC) Lapatinib (Tyverb) for early stage ErbB2 (HER2) over-expressing breast cancer - adjuvant treatment
2014     NIHR Horizon Scanning Centre (NIHR HSC) Recombinant human alpha-mannosidase (Lamazym) for alpha mannosidosis
2007     NIHR Horizon Scanning Centre (NIHR HSC) Milnacipran for fibromyalgia
2008     NIHR Horizon Scanning Centre (NIHR HSC) Canakinumab for cryopyrin associated periodic syndrome
2011     NIHR Horizon Scanning Centre (NIHR HSC) Lapatinib (Tyverb) for squamous cell carcinoma of the head and neck - adjuvant and maintenance therapy
2014     NIHR Horizon Scanning Centre (NIHR HSC) Metreleptin for generalised and partial lipodystrophy
2008     NIHR Horizon Scanning Centre (NIHR HSC) Prucalopride (Resolor) for chronic constipation
2011     NIHR Horizon Scanning Centre (NIHR HSC) Nitazoxanide for influenza - first line
2014     NIHR Horizon Scanning Centre (NIHR HSC) myVisionTrack® for monitoring degenerative eye disease
2007     NIHR Horizon Scanning Centre (NIHR HSC) Magnetic Source Imaging (MSI) for the characterisation and localisation of epileptic abnormalities and brain tumours
2008     NIHR Horizon Scanning Centre (NIHR HSC) AVE0010 (ZP10) for type 2 diabetes mellitus
2011     NIHR Horizon Scanning Centre (NIHR HSC) Pazopanib (Votrient) for ovarian, fallopian or peritoneal cancer
2014     NIHR Horizon Scanning Centre (NIHR HSC) Tabalumab for systemic lupus erythematosus
2007     NIHR Horizon Scanning Centre (NIHR HSC) SpeechEasy altered auditory feedback device for stammer
2008     NIHR Horizon Scanning Centre (NIHR HSC) Insulin glulisine (Apidra) for type 1 diabetes mellitus in adolescents and children
2011     NIHR Horizon Scanning Centre (NIHR HSC) Perampanel for epilepsy - adjunctive
2014     NIHR Horizon Scanning Centre (NIHR HSC) SafePlace for the peripheral insertion of central venous catheters in infants
2007     NIHR Horizon Scanning Centre (NIHR HSC) Oral alitretinoin for adults with chronic hand eczema
2008     NIHR Horizon Scanning Centre (NIHR HSC) Exenatide once-weekly for type 2 diabetes mellitus - second or third line
2011     NIHR Horizon Scanning Centre (NIHR HSC) Phentermine/topiramate (Qnexa) for weight loss and maintenance of weight loss
2014     NIHR Horizon Scanning Centre (NIHR HSC) Interferon beta-1a (Traumakine) for acute respiratory distress syndrome – first line
2007     NIHR Horizon Scanning Centre (NIHR HSC) CNTO-1275 (Ustekinumab) for moderate to severe psoriasis
2008     NIHR Horizon Scanning Centre (NIHR HSC) Alteplase (Activase) for the early (up to 4.5 hours) treatment of acute ischaemic stroke
2011     NIHR Horizon Scanning Centre (NIHR HSC) Rivaroxaban (Xarelto) for acute coronary syndrome
2014     NIHR Horizon Scanning Centre (NIHR HSC) Mepolizumab for severe refractory eosinophilic asthma – first line
2006     NIHR Horizon Scanning Centre (NIHR HSC) Bevacizumab (Avastin) for breast cancer - metastatic, first line (in combination with non-taxanes): horizon scanning technology briefing
2008     NIHR Horizon Scanning Centre (NIHR HSC) Ezetimibe (Ezetrol) for hypercholesterolaemia in adolescents
2011     NIHR Horizon Scanning Centre (NIHR HSC) Safinamide for early stage parkinson's disease - adjuvant therapy
2014     NIHR Horizon Scanning Centre (NIHR HSC) Brodalumab for moderate to severe plaque psoriasis
2007     NIHR Horizon Scanning Centre (NIHR HSC) Sunitinib (Sutent) for advanced and/or metastatic breast cancer
2008     NIHR Horizon Scanning Centre (NIHR HSC) Picoplatin for small cell lung cancer - second line
2011     NIHR Horizon Scanning Centre (NIHR HSC) Safinamide for mid-to-late stage parkinson's disease - adjuvant therapy
2008     NIHR Horizon Scanning Centre (NIHR HSC) Decitabine for acute myeloid leukaemia
2011     NIHR Horizon Scanning Centre (NIHR HSC) Sipuleucel-T (Provenge) for metastatic castration resistant prostate cancer - first line
2007     NIHR Horizon Scanning Centre (NIHR HSC) Erlotinib (Tarceva) in combination with bevacizumab for advanced or metastatic non-small cell lung cancer
2008     NIHR Horizon Scanning Centre (NIHR HSC) Denosumab (AMG162) for prevention of bone metastases in prostate cancer
2011     NIHR Horizon Scanning Centre (NIHR HSC) Strontium ranelate (Protelos) for osteoarthritis
2016     NIHR Horizon Scanning Centre (NIHR HSC) Vepoloxamer for vaso-occlusive crises in sickle cell disease – first line
2007     NIHR Horizon Scanning Centre (NIHR HSC) Sorafenib (Nexavar) for advanced non-small cell lung cancer
2008     NIHR Horizon Scanning Centre (NIHR HSC) BIBW 2992 (Tovok) for advanced or metastatic non-small cell lung cancer after failure of at least one reversible EGFR inhibitor
2011     NIHR Horizon Scanning Centre (NIHR HSC) Zonisamide (Zonegran) for newly diagnosed partial seizures in epilepsy
2016     NIHR Horizon Scanning Centre (NIHR HSC) Ofatumumab (Arzerra) for refractory follicular lymphoma – third line in combination with bendamustine
2007     NIHR Horizon Scanning Centre (NIHR HSC) Vandetanib (Zactima) for advanced or metastatic non-small cell lung cancer
2008     NIHR Horizon Scanning Centre (NIHR HSC) Bevacizumab (Avastin) in combination with docetaxel for metastatic breast cancer - first line
2011     NIHR Horizon Scanning Centre (NIHR HSC) LAS 41005 (Actikeral) for actinic keratosis - first line
2016     NIHR Horizon Scanning Centre (NIHR HSC) Medidur for non-infectious posterior uveitis – second line
2007     NIHR Horizon Scanning Centre (NIHR HSC) INGN 201 (contusugene ladenovec; Advexin) for recurrent and/or unresectable squamous cell carcinoma of the head and neck
2008     NIHR Horizon Scanning Centre (NIHR HSC) Erlotinib (Tarceva) for non small cell lung cancer advanced or metastatic-maintenance monotherapy
2011     NIHR Horizon Scanning Centre (NIHR HSC) Romidepsin (Istodax) for peripheral T-cell lymphoma, relapsed and/or refractory - second line
2016     NIHR Horizon Scanning Centre (NIHR HSC) Epoetin alfa (Eprex) for anaemia in adults with low or intermediate-1 risk myelodysplastic syndromes
2007     NIHR Horizon Scanning Centre (NIHR HSC) INGN 201 (contusugene ladenovec; Advexin) for Li-Fraumeni syndrome associated cancers
2008     NIHR Horizon Scanning Centre (NIHR HSC) Denosumab (AMG162) for the prevention of therapy-induced bone loss in non-metastatic breast and prostate cancer
2011     NIHR Horizon Scanning Centre (NIHR HSC) Tivozanib for renal cell cancer, locally advanced or metastatic - first line
2016     NIHR Horizon Scanning Centre (NIHR HSC) Naldemedine for opioid-induced constipation in adults
2007     NIHR Horizon Scanning Centre (NIHR HSC) Arsenic trioxide (Trisenox) for acute promyelocytic leukaemia - first line therapy
2008     NIHR Horizon Scanning Centre (NIHR HSC) Denosumab (AMG 162) for bone metastases from solid tumours and multiple myeloma
2011     NIHR Horizon Scanning Centre (NIHR HSC) Trastuzumab-DM1 (Herceptin-DM1) for breast cancer, locally advanced or metastatic, HER2 positive - second or third line
2012     NIHR Horizon Scanning Centre (NIHR HSC) Dacomitinib for advanced or metastatic non-small cell lung cancer – second or third line
2016     NIHR Horizon Scanning Centre (NIHR HSC) Pegvaliase for the treatment of hyperphenylalaninaemia in adults with phenylketonuria – first line
2007     NIHR Horizon Scanning Centre (NIHR HSC) Plerixafor (Mozobil) for stem-cell mobilisation in multiple myeloma
2008     NIHR Horizon Scanning Centre (NIHR HSC) Amrubicin for small cell lung cancer - relapsed and/or refractory, extensive disease
2011     NIHR Horizon Scanning Centre (NIHR HSC) Trastuzumab SC (Herceptin SC) for breast cancer, early or metastatic, HER2 positive - monotherapy or combination therapy, including neo-adjuvant and adjuvant use
2012     NIHR Horizon Scanning Centre (NIHR HSC) Dovitinib for metastatic renal cell carcinoma
2016     NIHR Horizon Scanning Centre (NIHR HSC) KRN23 for X-linked hypophosphataemia in children aged 5-12 years – first line
2008     NIHR Horizon Scanning Centre (NIHR HSC) Voclosporin (LX-211) for non-infectious uveitis
2011     NIHR Horizon Scanning Centre (NIHR HSC) Mipomersen for familial hypercholesterolemia - third or fourth line
2012     NIHR Horizon Scanning Centre (NIHR HSC) Enobosarm (Ostarine) for cachexia in patients with advanced non-small cell lung cancer – first line
2013     NIHR Horizon Scanning Centre (NIHR HSC) Eribulin mesilate (Halaven) for advanced non-small cell lung cancer – third line
2016     NIHR Horizon Scanning Centre (NIHR HSC) Empagliflozin (Jardiance) for preventing cardiovascular death in patients with type 2 diabetes mellitus and high cardiovascular risk
2007     NIHR Horizon Scanning Centre (NIHR HSC) Rituximab (Mabthera) for non-Hodgkin’s lymphoma – first line maintenance therapy
2008     NIHR Horizon Scanning Centre (NIHR HSC) Rolofylline for acute heart failure
2011     NIHR Horizon Scanning Centre (NIHR HSC) Bromocriptine, quick release (Syncroset) for type 2 diabetes mellitus
2012     NIHR Horizon Scanning Centre (NIHR HSC) Enzastaurin for diffuse large B-cell lymphoma – following complete remission
2013     NIHR Horizon Scanning Centre (NIHR HSC) Olaparib for relapsed platinum-sensitive ovarian cancer
2016     NIHR Horizon Scanning Centre (NIHR HSC) Empagliflozin (Jardiance) for type 1 diabetes – adjunctive therapy
2007     NIHR Horizon Scanning Centre (NIHR HSC) Aflibercept (VEGF Trap) for advanced chemo-refractory epithelial ovarian cancer
2008     NIHR Horizon Scanning Centre (NIHR HSC) Lorcaserin hydrochloride (APD-356) for obesity or overweight people with at least one co-morbidity
2011     NIHR Horizon Scanning Centre (NIHR HSC) Brentuximab vedotin for systemic anaplastic large cell lymphoma relapsed and/or refractory - first line
2012     NIHR Horizon Scanning Centre (NIHR HSC) Everolimus (Afinitor) for advanced, unresectable or metastatic neuroendocrine tumours
2013     NIHR Horizon Scanning Centre (NIHR HSC) Plitidepsin (Aplidin) in combination with dexamethasone for multiple myeloma – third line
2016     NIHR Horizon Scanning Centre (NIHR HSC) Venetoclax with rituximab for relapsed or refractory chronic lymphocytic leukaemia – second and subsequent line
2007     NIHR Horizon Scanning Centre (NIHR HSC) Trabectedin (Yondelis) for relapsed ovarian cancer
2008     NIHR Horizon Scanning Centre (NIHR HSC) Irbesartan (Aprovel) for heart failure with preserved systolic function
2011     NIHR Horizon Scanning Centre (NIHR HSC) Brentuximab vedotin for Hodgkin's lymphoma, relapsing or remitting - first line
2012     NIHR Horizon Scanning Centre (NIHR HSC) Nanoliposomal irinotecan for metastatic pancreatic cancer in patients who have progressed on prior gemcitabine-based therapy
2013     NIHR Horizon Scanning Centre (NIHR HSC) Darapladib for cardiovascular risk reduction in patients with coronary heart disease – add on therapy
2016     NIHR Horizon Scanning Centre (NIHR HSC) Pelareorep in combination with paclitaxel for recurrent or persistent epithelial ovarian, fallopian tube or primary peritoneal cancer
2007     NIHR Horizon Scanning Centre (NIHR HSC) Vandetanib (Zactima, -6474, AZD-6474, ZD6474) for medullary thyroid cancer – locally advanced or metastatic
2008     NIHR Horizon Scanning Centre (NIHR HSC) Irbesartan (Aprovel) for prevention of cardiovascular complications in patients with persistent atrial fibrillation
2011     NIHR Horizon Scanning Centre (NIHR HSC) Zibotentan in combination with docetaxel for prostate cancer, metastatic, castration resistant - in combination with docetaxel
2012     NIHR Horizon Scanning Centre (NIHR HSC) Ofatumumab (Arzerra) for maintenance treatment in relapsed chronic lymphocytic leukaemia (CLL) patients responding to induction therapy
2013     NIHR Horizon Scanning Centre (NIHR HSC) Ezetimibe and simvastatin (Inegy) for reduction of cardiovascular risk in coronary heart disease