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Year Source Title
2021     NIHR Health Technology Assessment programme Long limb compared with standard limb Roux-en-Y gastric bypass for type 2 diabetes and obesity: the LONG LIMB RCT
2021     Scottish Health Technologies Group (SHTG) Chest wall bracing for children and young people with pectus carinatum
2021     The National Health Care Institute (ZIN, Zorginstituut Nederland) Package advice pertuzumab and trastuzumab (Phesgo®) for the treatment of breast cancer
2021     Institut für Qualität und Wirtschaftlichkeit im Gesundheitswesen (IQWiG) [Risdiplam (spinal muscular atrophy) - Benefit assessment according to §35a Social Code Book V]
2021     Agència de Qualitat i Avaluació Sanitàries de Catalunya (AQuAS) [Analysis of the volume-outcome relationship in digestive cancer surgery]
2021     The National Health Care Institute (ZIN, Zorginstituut Nederland) Package advice onasemnogene abeparvovec (Zolgensma®) for the treatment of SMA
2021     Agència de Qualitat i Avaluació Sanitàries de Catalunya (AQuAS) [Femtosecond laser-assisted cataract surgery (FLACS). Effectiveness, security and efficiency assessment]
2021     The National Health Care Institute (ZIN, Zorginstituut Nederland) GVS advice inclisiran (Leqvio®) for the treatment of hypercholesterolemia
2021     Institut für Qualität und Wirtschaftlichkeit im Gesundheitswesen (IQWiG) [Self-application of an active motion splint within the treatment of ankle fractures]
2021     Agency for Healthcare Research and Quality (AHRQ) Automated-entry patient-generated health data for chronic conditions: the evidence on health outcomes
2021     The National Health Care Institute (ZIN, Zorginstituut Nederland) Advice on the clustering of combination products and ghost clusters in GVS
2021     Institut für Qualität und Wirtschaftlichkeit im Gesundheitswesen (IQWiG) [Satralizumab (neuromyelitis optica spectrum disorders) - Assessment according to §35a (para. 1., sentence 11) Social Code Book V]
2021     Agency for Healthcare Research and Quality (AHRQ) Breast reconstruction after mastectomy
2021     The National Health Care Institute (ZIN, Zorginstituut Nederland) GVS advice elexacaftor/tezacaftor/ivacaftor (Kaftrio®) in combination with ivacaftor (Kalydeco®)
2021     Institut für Qualität und Wirtschaftlichkeit im Gesundheitswesen (IQWiG) [Empagliflozin (heart failure) - Benefit assessment according to §35a Social Code Book V]
2021     The National Health Care Institute (ZIN, Zorginstituut Nederland) GVS assessment of trientine dihydrochloride (Cufence®) for the treatment of Wilson’s disease
2021     Institut für Qualität und Wirtschaftlichkeit im Gesundheitswesen (IQWiG) [Tralokinumab (atopic dermatitis) - Benefit assessment according to §35a Social Code Book V]
2021     Agency for Healthcare Research and Quality (AHRQ) Care coordination and care plans for transitions across care settings
2021     The National Health Care Institute (ZIN, Zorginstituut Nederland) GVS assessment of crisaborole (Staquis®) for the treatment of atopic dermatitis
2021     Institut für Qualität und Wirtschaftlichkeit im Gesundheitswesen (IQWiG) [Angiotensin II acetate (hypotension) - Benefit assessment according to §35a Social Code Book V]
2021     Basque Office for Health Technology Assessment (OSTEBA) [Efficacy of high flow oxygen therapy for the treatment of respiratory distress in children]
2021     The National Health Care Institute (ZIN, Zorginstituut Nederland) GVS assessment of rivaroxaban (Xarelto®) for the treatment of VTE and prevention of VTE recurrence in children
2021     Institut für Qualität und Wirtschaftlichkeit im Gesundheitswesen (IQWiG) [Onasemnogene abeparvovec (spinal muscular atrophy) - Benefit assessment according to §35a Social Code Book V - Addendum]
2021     Agency for Healthcare Research and Quality (AHRQ) Cervical ripening in the outpatient setting
2021     The National Health Care Institute (ZIN, Zorginstituut Nederland) Advice on a potential candidate for conditional inclusion of entrectinib (Rozlytrek®) for solid tumours with NTRK gene fusion
2021     Institut für Qualität und Wirtschaftlichkeit im Gesundheitswesen (IQWiG) [Relationship between volume of services and quality of treatment outcome for complex procedures of the pancreas - Rapid Report]
2021     Institut für Qualität und Wirtschaftlichkeit im Gesundheitswesen (IQWiG) [Isatuximab (multiple myeloma after >= 1 prior therapy, combination with carfilzomib und dexamethasone) - Benefit assessment according to §35a Social Code Book V - Addendum]
2021     The National Health Care Institute (ZIN, Zorginstituut Nederland) Advice on a potential candidate for conditional inclusion of larotrectinib (Vitrakvi®) for solid tumours with NTRK gene fusion
2021     Institut für Qualität und Wirtschaftlichkeit im Gesundheitswesen (IQWiG) [Isatuximab (multiple myeloma after >= 2 prior therapies, combination with pomalidomide and dexamethasone) - Benefit assessment according to §35a Social Code Book V - Addendum]
2021     The National Health Care Institute (ZIN, Zorginstituut Nederland) GVS assessment of 13-valent pneumococcal conjugate vaccine (Prevenar13®) for medical high-risk groups
2021     Institut für Qualität und Wirtschaftlichkeit im Gesundheitswesen (IQWiG) [Cognitive behavioural therapy for insomnia - Evidence report for the S3 guideline on non-restorative sleep/sleep disorders - Insomnia in adults]
2021     Health Information and Quality Authority (HIQA) Systematic review of cost-effectiveness – management of chronic obstructive pulmonary disease in adults
2021     Austrian Institute for Health Technology Assessment (AIHTA) The economic and societal dimension of parental mental illness. Part 1: systematic review. Part II: economic evaluation framework
2021     The National Health Care Institute (ZIN, Zorginstituut Nederland) GVS assessment of Brimonidine Stulln 2mg/ml eye drop solution for decrease of increased intraocular pressure (IOP) in patients with open-angle glaucoma or ocular hypertension
2021     Institut für Qualität und Wirtschaftlichkeit im Gesundheitswesen (IQWiG) [Blinatumomab (acute lymphoblastic leukaemia, Ph-, CD19+, children aged 1 to 18 years) - Assessment according to §35a (para. 1., sentence 11) Social Code Book V]
2021     Health Information and Quality Authority (HIQA) Budget impact analysis – management of chronic obstructive pulmonary disease in adults
2021     Austrian Institute for Health Technology Assessment (AIHTA) ≥ 12 month follow-up of patients with spinal muscular atrophy (SMA) treated with Spinraza®, Zolgensma® or combination therapies
2021     The National Health Care Institute (ZIN, Zorginstituut Nederland) GVS assessment of formoterol/ glycopyrronium/ budesonide (Trixeo® aerosphere)
2021     Institut für Qualität und Wirtschaftlichkeit im Gesundheitswesen (IQWiG) [Atezolizumab (NSCLC; first line) - Benefit assessment according to §35a Social Code Book V - Addendum]
2021     The National Health Care Institute (ZIN, Zorginstituut Nederland) GVS assessment of sodium zirconium cyclosilicate (Lokelma®) for the treatment of hyperkalemia
2021     Institut für Qualität und Wirtschaftlichkeit im Gesundheitswesen (IQWiG) [Cemiplimab (basal cell carcinoma) - Benefit assessment according to §35a Social Code Book V]
2021     Agency for Healthcare Research and Quality (AHRQ) Disparities and barriers to pediatric cancer survivorship care
2021     NIHR Health Technology Assessment programme POSNOC-POsitive Sentinel NOde: adjuvant therapy alone versus adjuvant therapy plus Clearance or axillary radiotherapy: a randomised controlled trial of axillary treatment in women with early-stage breast cancer who have metastases in one or two sentinel nodes
2021     The National Health Care Institute (ZIN, Zorginstituut Nederland) Package advice multiple myeloma
2021     Institut für Qualität und Wirtschaftlichkeit im Gesundheitswesen (IQWiG) [Teriflunomide (multiple sclerosis) - Benefit assessment according to §35a Social Code Book V]
2021     Health Information and Quality Authority (HIQA) Budget impact analysis – National Clinical Guideline. Unexpected intraoperative life threatening haemorrhage guideline
2021     The National Health Care Institute (ZIN, Zorginstituut Nederland) GVS assessment of opicapone (Ongentys®) for the treatment of Parkinson's disease
2021     Institut für Qualität und Wirtschaftlichkeit im Gesundheitswesen (IQWiG) [Daratumumab (multiple myeloma) - Benefit assessment according to §35a Social Code Book V]
2021     Health Information and Quality Authority (HIQA) Budget impact analysis – stop smoking
2021     Institute for Clinical Effectiveness and Health Policy (IECS) [Equine immunoglobulin F(ab’)2 fragments (hyperimmune equine serum) for COVID-19]
2021     The National Health Care Institute (ZIN, Zorginstituut Nederland) GVS assessment of givosiran (Givlaari®) for the treatment of acute hepatic porphyria
2021     Institut für Qualität und Wirtschaftlichkeit im Gesundheitswesen (IQWiG) [Daratumumab (systemic light chain amyloidosis) - Benefit assessment according to §35a Social Code Book V]
2021     Institut für Qualität und Wirtschaftlichkeit im Gesundheitswesen (IQWiG) [Acalabrutinib (pretreated chronic lymphocytic leukaemia) - Second Addendum to Commission A20-105]
2021     NIHR Health Technology Assessment programme Primary trabeculectomy versus primary glaucoma eye drops for newly diagnosed advanced glaucoma: TAGS RCT
2021     Institute for Clinical Effectiveness and Health Policy (IECS) [Ivermectin for COVID-19]
2021     The National Health Care Institute (ZIN, Zorginstituut Nederland) GVS assessment oxybutynin intravesical solution (Vesolox®)
2021     Institut für Qualität und Wirtschaftlichkeit im Gesundheitswesen (IQWiG) [Cenobamate (epilepsy) - Addendum to Commission A21-78]
2021     Malaysian Health Technology Assessment (MaHTAS) Rezūm therapy for management of benign prostatic hyperplasia
2021     Institut für Qualität und Wirtschaftlichkeit im Gesundheitswesen (IQWiG) [Cemiplimab (non-small cell lung cancer) - Benefit assessment according to §35a Social Code Book V]
2021     NIHR Health Technology Assessment programme Sacral nerve stimulation versus the magnetic sphincter augmentation device for adult faecal incontinence: the SaFaRI RCT
2021     Institute for Clinical Effectiveness and Health Policy (IECS) [Flash glucose monitoring system in diabetes mellitus patients]
2021     Agency for Care Effectiveness (ACE) MRI-US fusion targeted biopsy for diagnosis of prostate cancer
2021     The National Health Care Institute (ZIN, Zorginstituut Nederland) GVS advice mexiletine (Namuscla®)
2021     Institut für Qualität und Wirtschaftlichkeit im Gesundheitswesen (IQWiG) [Enzalutamide (prostate cancer) - Addendum to Commission A21-77]
2021     Malaysian Health Technology Assessment (MaHTAS) 5-aminolevulinic acid (5-ALA) for brain tumour surgical procedure
2021     Institut für Qualität und Wirtschaftlichkeit im Gesundheitswesen (IQWiG) [Nivolumab (colorectal cancer) - Benefit assessment according to §35a Social Code Book V]
2021     Institute for Clinical Effectiveness and Health Policy (IECS) [Ketogenic diet in central nervous system tumors]
2021     Agency for Care Effectiveness (ACE) Transcatheter mitral valve leaflet repair for patients with mitral regurgitation
2021     Institut für Qualität und Wirtschaftlichkeit im Gesundheitswesen (IQWiG) [Bosutinib (chronic myeloid leukaemia) - Benefit assessment according to §35a Social Code Book V. Addendum]
2021     Malaysian Health Technology Assessment (MaHTAS) Single dose rifampicin (SDR) as a prophylaxis for leprosy contacts
2021     Institut für Qualität und Wirtschaftlichkeit im Gesundheitswesen (IQWiG) [Internet- or mobile-based cognitive behavioral therapy for insomnia - Evidence report for the S3 guideline on non-restorative sleep/sleep disorders - Insomnia in adults]
2021     Institute for Clinical Effectiveness and Health Policy (IECS) [Teduglutide in short bowel syndrome]
2021     Agency for Care Effectiveness (ACE) Transcatheter aortic valve implantation (TAVI) for patients with symptomatic severe aortic stenosis
2021     Institut für Qualität und Wirtschaftlichkeit im Gesundheitswesen (IQWiG) [High frequency ablation of the endometrium using a mesh electrode in patients with menorrhagia]
2021     Malaysian Health Technology Assessment (MaHTAS) Versajet hydrosurgery system for wound debridement: an update
2021     Institut für Qualität und Wirtschaftlichkeit im Gesundheitswesen (IQWiG) [Vandetanib (medullary thyroid cancer) - Benefit assessment according to §35a Social Code Book V (expiry of the limitation period)]
2021     Institute for Clinical Effectiveness and Health Policy (IECS) [Dipeptidyl-peptidase 4 inhibitors in patients with prediabetes or metabolic syndrome]
2021     Agency for Care Effectiveness (ACE) Photodynamic therapy for treating non-melanoma skin tumours
2021     Institut für Qualität und Wirtschaftlichkeit im Gesundheitswesen (IQWiG) [Selumetinib (treatment of neurofibromas in neurofibromatosis) - Assessment according to §35a (para. 1., sentence 11) Social Code Book V]
2021     Institut für Qualität und Wirtschaftlichkeit im Gesundheitswesen (IQWiG) [Vosoritide (achondroplasia) - Assessment according to §35a (para. 1., sentence 11) Social Code Book V]
2021     Institute for Clinical Effectiveness and Health Policy (IECS) [Tolvaptan in autosomal dominant polycystic kidney disease]
2021     Agency for Care Effectiveness (ACE) Cochlear implants for treating adults with single-sided deafness (SSD)
2021     Institut für Qualität und Wirtschaftlichkeit im Gesundheitswesen (IQWiG) [Venetoclax (acute myeloid leukaemia) - Benefit assessment according to §35a Social Code Book V - Addendum]
2021     Institute for Clinical Effectiveness and Health Policy (IECS) [Tocilizumab in COVID-19 patients]
2021     Agency for Care Effectiveness (ACE) Antibacterial envelope for the prevention of cardiac implantable electronic device-related infections
2021     Institut für Qualität und Wirtschaftlichkeit im Gesundheitswesen (IQWiG) [Dostarlimab (endometrial cancer) - Benefit assessment according to §35a Social Code Book V - Addendum]
2021     Agency for Healthcare Research and Quality (AHRQ) Integrated and comprehensive pain management programs: effectiveness and harms
2021     Institute for Clinical Effectiveness and Health Policy (IECS) [Allocation of scarce resources in critical care units in a pandemic]
2021     Agency for Care Effectiveness (ACE) Repetitive transcranial magnetic stimulation for adults with treatment resistant major depressive disorder
2021     Institut für Qualität und Wirtschaftlichkeit im Gesundheitswesen (IQWiG) [Dostarlimab (endometrial cancer) - Second addendum to commission A21-84]
2021     Agency for Healthcare Research and Quality (AHRQ) Integrating palliative care in ambulatory care of noncancer serious chronic illness: a mixed-methods review
2021     Agència de Qualitat i Avaluació Sanitàries de Catalunya (AQuAS) [Review of the evidence on the impact of school closures through the evolution of the COVID-19 pandemic]
2021     NIHR Health Technology Assessment programme Cognitive–behavioural therapy for a variety of conditions: an overview of systematic reviews and panoramic meta-analysis
2021     Institute for Clinical Effectiveness and Health Policy (IECS) [SGLT2 inhibitors in heart failure]
2021     Institut für Qualität und Wirtschaftlichkeit im Gesundheitswesen (IQWiG) [Nivolumab (malignant pleural mesothelioma) - Addendum to Commission A21-89]
2021     NIHR Health Technology Assessment programme Patch augmentation surgery for rotator cuff repair: the PARCS mixed-methods feasibility study
2021     Institute for Clinical Effectiveness and Health Policy (IECS) [Ambulatory oxygen therapy in COVID-19]
2021     Institut für Qualität und Wirtschaftlichkeit im Gesundheitswesen (IQWiG) [Misoprostol (induction of labour) - Benefit assessment according to §35a Social Code Book V]
2021     Agency for Healthcare Research and Quality (AHRQ) Interventional treatments for acute and chronic pain: systematic review
2021     NIHR Health Services and Delivery Research programme Respite care and short breaks for young adults aged 18–40 with complex health-care needs: mixed-methods systematic review and conceptual framework development