[Portable neuromodulation stimulation device to improve gait in multiple sclerosis]

Duarte-Díaz A, Perestelo-Pérez L, Rivero-Santana A, Infante-Ventura D, Toledo-Chávarri A, Cazaña-Pérez V, Rodríguez-Rodríguez L, Rivas Ruiz F, Serrano-Aguilar P
Record ID 32018005344
Spanish
Original Title: Dispositivo de neuromodulación portátil para la ayuda a la marcha en esclerosis múltiple
Authors' results and conclusions: Key points • Multiple sclerosis (MS) is an autoimmune-mediated neurodegenerative disease characterized by inflammatory demyelination with axonal transection at different levels of the central nervous system. • There is a wide range of symptoms associated with MS, and it can cause pretty much any neurological symptom caused by a central nervous system lesion. Patients and caregivers perceive motor problems as particularly disabling. • The PoNS™ device is a non-implantable, translingual stimulation device that uses small electrodes to provide mild electrical stimulation to afferent nerve fibers located on the dorsal surface of the tongue. The PoNS™ device has been used in conjunction with gait training sessions conducted by physiotherapists. • The current scientific evidence on the PoNS™ device for gait assistance in MS is too limited to draw robust conclusions about its effects, mainly due to the few studies conducted and the small sample sizes (34 participants in total). • Two randomized controlled trials identified in this report found that people using the PoNS™ device with an individualized physical therapy program significantly improved their gait pattern after 14 weeks. In only one of them, however, this improvement was significantly greater than the obtained with simulated stimulation and physiotherapy. • The available evidence indicates that the PoNS™ device is both feasible and safe. However, high-quality, industry-independent clinical trials with appropriate sample size are required to determine whether it is an effective adjunct to gait rehabilitation programs in people with MS.
Details
Project Status: Completed
Year Published: 2022
URL for published report: https://sescs.es/wp-content/uploads/2015/09/SESCS_NEUROMODULACION_PORTATIL_DEF_NIPO.pdf?x68814
Requestor: Ministry of Health
English language abstract: An English language summary is available
Publication Type: Other
Country: Spain
MeSH Terms
  • Multiple Sclerosis
  • Gait
  • Electric Stimulation Therapy
  • Gait Disorders, Neurologic
Keywords
  • Esclerosis Múltiple
  • Dispositivo PoNS™
  • Estimulación translingual
  • Neuromodulación no invasiva de los nervios craneales
  • Neuromodulación portátil
Contact
Organisation Name: Canary Health Service
Contact Address: Dirección del Servicio. Servicio Canario de la Salud, Camino Candelaria 44, 1ª planta, 38109 El Rosario, Santa Cruz de Tenerife
Contact Name: sescs@sescs.es
Contact Email: sescs@sescs.es
This is a bibliographic record of a published health technology assessment from a member of INAHTA or other HTA producer. No evaluation of the quality of this assessment has been made for the HTA database.