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Year Source Title
2021 Agency for Care Effectiveness (ACE) Repetitive transcranial magnetic stimulation for adults with treatment resistant major depressive disorder
2021 Agency for Care Effectiveness (ACE) Golimumab for the treatment of rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis and ulcerative colitis
2021 Agency for Care Effectiveness (ACE) Rituximab for treating non-Hodgkin's lymphoma and chronic lymphocytic leukaemia
2021 Agency for Care Effectiveness (ACE) Tenofovir alafenamide for treating chronic hepatitis B infection
2021 Agency for Care Effectiveness (ACE) Metformin extended release for treating type 2 diabetes mellitus
2021 Agency for Care Effectiveness (ACE) Guselkumab, ixekizumab and secukinumab for treating chronic plaque psoriasis
2021 Agency for Care Effectiveness (ACE) Ixekizumab and secukinumab for treating active psoriatic arthritis
2021 Agency for Care Effectiveness (ACE) Dacomitinib for treating EGFR mutation-positive non-small-cell lung cancer
2021 Agency for Care Effectiveness (ACE) Ixekizumab and secukinumab for treating active ankylosing spondylitis
2021 National Authority for Assessment and Accreditation in Healthcare (INEAS) ZELBORAF® (vemurafenib) en monothérapie dans le traitement du mélanome non résécable ou métastatique à mutation BRAF V600
2021 Institute for Clinical and Economic Review (ICER) Tezepelumab for severe asthma
2021 Institute for Clinical and Economic Review (ICER) Mavacamten for hypertrophic cardiomyopathy: effectiveness and value
2021 Institute for Clinical and Economic Review (ICER) Eculizumab and efgartigimod for the treatment of myasthenia gravis: effectiveness and value
2021 Institute for Clinical and Economic Review (ICER) Observational real-world evidence update. Prophylaxis of hereditary angioedema with Takhzyro and C1 inhibitors: effectiveness and value
2021 Institute for Clinical and Economic Review (ICER) JAK inhibitors and monoclonal antibodies for the treatment of atopic dermatitis: effectiveness and value
2021 Institute for Clinical and Economic Review (ICER) Aducanumab for Alzheimer's disease: effectiveness and value
2021 Institute for Clinical and Economic Review (ICER) Anti b-cell maturation antigen CAR T-cell and antibody drug conjugate therapy for heavily pre-treated relapsed and refractory multiple myeloma
2021 Institute for Clinical and Economic Review (ICER) Belimumab and voclosporin for lupus nephritis: effectiveness and value
2021 Institute for Clinical and Economic Review (ICER) Treatments for anemia in chronic kidney disease: effectiveness and value
2021 Institute for Clinical and Economic Review (ICER) Bempedoic acid and inclisiran for patients with heterozygous familial hypercholesterolemia and for secondary prevention of ASCVD: effectiveness and value
2021 Center for Drug Evaluation (CDE) Real-world results of immune checkpoint inhibitors from the Taiwan National Health Insurance Registration System
2021 Center for Drug Evaluation (CDE) Effects of direct-acting antiviral therapy for patients with advanced hepatocellular carcinoma and concomitant hepatitis C-A population-based cohort study
2021 Health Technology Wales (HTW) Transcranial magnetic stimulation for the treatment of depression
2021 The National Health Care Institute (ZIN, Zorginstituut Nederland) Package advice ravulizumab (Ultomiris®) for the treatment of PNH and aHUS
2021 The National Health Care Institute (ZIN, Zorginstituut Nederland) GVS advice tirbanibulin (Klisyri®) for the treatment of adults with actinic keratosis
2021 The National Health Care Institute (ZIN, Zorginstituut Nederland) Package advice venetoclax (Venclyxto®)
2021 The National Health Care Institute (ZIN, Zorginstituut Nederland) GVS assessment ponesimod (Ponvory®) for the treatment of relapsing forms of multiple sclerosis (RMS)
2021 The National Health Care Institute (ZIN, Zorginstituut Nederland) Package advice cemiplimab (Libtayo®) for the treatment of non-small cell lung carcinoma (NSCLC)
2021 The National Health Care Institute (ZIN, Zorginstituut Nederland) GVS assessment empagliflozin (Jardiance®) for the treatment of adults with chronic heart failure
2021 The National Health Care Institute (ZIN, Zorginstituut Nederland) GVS review levomepromazine (Nozinan®) for palliative sedation in a home situation
2021 The National Health Care Institute (ZIN, Zorginstituut Nederland) Extension of further conditions for SGLT2 inhibitors following recent GVS advice (22 June 2021)
2021 The National Health Care Institute (ZIN, Zorginstituut Nederland) GVS advice CGRP inhibitors erenumab, fremanezumab, galcanezumab (Aimovig®, AJOVY®, Emgality®) for the treatment of patients with episodic and chronic migraine
2021 The National Health Care Institute (ZIN, Zorginstituut Nederland) GVS advice roxadustat (Evrenzo®) for the treatment of symptomatic anaemia in chronic kidney damage
2021 The National Health Care Institute (ZIN, Zorginstituut Nederland) GVS advice drospirenon-estetrol (Drovelis®)
2021 The National Health Care Institute (ZIN, Zorginstituut Nederland) Follow-up advice on conditional inclusion of larotrectinib (Vitrakvi®)
2021 The National Health Care Institute (ZIN, Zorginstituut Nederland) Follow-up advice on conditional inclusion of entrectinib (Rozlytrek®)
2021 The National Health Care Institute (ZIN, Zorginstituut Nederland) Package advice ipilimumab (Yervoy®) in combination with nivolumab (Opdivo®)
2021 The National Health Care Institute (ZIN, Zorginstituut Nederland) GVS advice on the reassessment of tafamidis (Vyndaqel®)
2021 The National Health Care Institute (ZIN, Zorginstituut Nederland) Advice on the reassessment of axicabtagene ciloleucel (Yescarta®)
2021 The National Health Care Institute (ZIN, Zorginstituut Nederland) GVS advice on ferrimaltol (Feraccru®) for treating iron deficiency
2021 The National Health Care Institute (ZIN, Zorginstituut Nederland) GVS advice on subcutaneous buprenorphine (Buvidal®)
2021 The National Health Care Institute (ZIN, Zorginstituut Nederland) Package advice for the lock procedure drug betibeglogene autotemcel (Zynteglo®)
2021 The National Health Care Institute (ZIN, Zorginstituut Nederland) Package advice on avelumab (Bavencio®) for treating urothelial cell carcinoma
2021 The National Health Care Institute (ZIN, Zorginstituut Nederland) Package advice on entrectinib (Rozlytrek®) for the treatment of ROS1 fusion-positive advanced non-small cell lung cancer
2021 The National Health Care Institute (ZIN, Zorginstituut Nederland) GVS advice for cladribine (Mavenclad®) – extension of further conditions
2021 The National Health Care Institute (ZIN, Zorginstituut Nederland) GVS assessment of calcifediol (Hidroferol®)
2021 The National Health Care Institute (ZIN, Zorginstituut Nederland) Package advice niraparib (Zejula®)
2021 The National Health Care Institute (ZIN, Zorginstituut Nederland) GVS advice SGLT-2 inhibitors
2021 The National Health Care Institute (ZIN, Zorginstituut Nederland) GVS advice RZV (Shingrix®) for the prevention of herpes zoster and related post-herpetic neuralgia
2021 The National Health Care Institute (ZIN, Zorginstituut Nederland) GVS advice avatrombopag (Doptelet®) for the treatment of thrombocytopenia
2021 The National Health Care Institute (ZIN, Zorginstituut Nederland) GVS advice Vocabria® and Rekambys® for the treatment of HIV-1 infection
2021 The National Health Care Institute (ZIN, Zorginstituut Nederland) Package advice isatuximab (Sarclisa®) for the treatment of multiple myeloma
2021 The National Health Care Institute (ZIN, Zorginstituut Nederland) GVS advice ivacaftor (Kalydeco®) extension of further conditions
2021 The National Health Care Institute (ZIN, Zorginstituut Nederland) GVS advice dapagliflozin (Forxiga®) extension of further condition
2021 The National Health Care Institute (ZIN, Zorginstituut Nederland) Package advice pertuzumab and trastuzumab (Phesgo®) for the treatment of breast cancer
2021 The National Health Care Institute (ZIN, Zorginstituut Nederland) Package advice onasemnogene abeparvovec (Zolgensma®) for the treatment of SMA
2021 The National Health Care Institute (ZIN, Zorginstituut Nederland) GVS advice inclisiran (Leqvio®) for the treatment of hypercholesterolemia
2021 The National Health Care Institute (ZIN, Zorginstituut Nederland) Advice on the clustering of combination products and ghost clusters in GVS
2021 The National Health Care Institute (ZIN, Zorginstituut Nederland) GVS advice elexacaftor/tezacaftor/ivacaftor (Kaftrio®) in combination with ivacaftor (Kalydeco®)
2021 The National Health Care Institute (ZIN, Zorginstituut Nederland) GVS assessment of trientine dihydrochloride (Cufence®) for the treatment of Wilson’s disease
2021 The National Health Care Institute (ZIN, Zorginstituut Nederland) GVS assessment of crisaborole (Staquis®) for the treatment of atopic dermatitis
2021 The National Health Care Institute (ZIN, Zorginstituut Nederland) GVS assessment of rivaroxaban (Xarelto®) for the treatment of VTE and prevention of VTE recurrence in children
2021 The National Health Care Institute (ZIN, Zorginstituut Nederland) Advice on a potential candidate for conditional inclusion of entrectinib (Rozlytrek®) for solid tumours with NTRK gene fusion
2021 The National Health Care Institute (ZIN, Zorginstituut Nederland) Advice on a potential candidate for conditional inclusion of larotrectinib (Vitrakvi®) for solid tumours with NTRK gene fusion
2021 The National Health Care Institute (ZIN, Zorginstituut Nederland) GVS assessment of 13-valent pneumococcal conjugate vaccine (Prevenar13®) for medical high-risk groups
2021 The National Health Care Institute (ZIN, Zorginstituut Nederland) GVS assessment of Brimonidine Stulln 2mg/ml eye drop solution for decrease of increased intraocular pressure (IOP) in patients with open-angle glaucoma or ocular hypertension
2021 The National Health Care Institute (ZIN, Zorginstituut Nederland) GVS assessment of formoterol/ glycopyrronium/ budesonide (Trixeo® aerosphere)
2021 The National Health Care Institute (ZIN, Zorginstituut Nederland) GVS assessment of sodium zirconium cyclosilicate (Lokelma®) for the treatment of hyperkalemia
2021 The National Health Care Institute (ZIN, Zorginstituut Nederland) Package advice multiple myeloma
2021 The National Health Care Institute (ZIN, Zorginstituut Nederland) GVS assessment of opicapone (Ongentys®) for the treatment of Parkinson's disease
2021 The National Health Care Institute (ZIN, Zorginstituut Nederland) GVS assessment of givosiran (Givlaari®) for the treatment of acute hepatic porphyria
2021 The National Health Care Institute (ZIN, Zorginstituut Nederland) GVS assessment oxybutynin intravesical solution (Vesolox®)
2021 The National Health Care Institute (ZIN, Zorginstituut Nederland) GVS advice mexiletine (Namuscla®)
2021 Institut für Qualität und Wirtschaftlichkeit im Gesundheitswesen (IQWiG) [Relationship between volume of services and quality of treatment outcome for complex procedures of the pancreas - Rapid Report]
2021 Institut für Qualität und Wirtschaftlichkeit im Gesundheitswesen (IQWiG) [Ibalizumab (HIV infection) - Benefit assessment according to §35a Social Code Book V]
2021 Institut für Qualität und Wirtschaftlichkeit im Gesundheitswesen (IQWiG) [Evidence report for the S3 guideline on dementia: Structural imaging]
2021 Institut für Qualität und Wirtschaftlichkeit im Gesundheitswesen (IQWiG) [Evidence report for the S3 guideline on dementia: Non-drug interventions for mild cognitive impairment and biomarker evidence]
2021 Institut für Qualität und Wirtschaftlichkeit im Gesundheitswesen (IQWiG) [Ixekizumab (axial spondyloarthritis) - Addendum to Commission A20-66]
2021 Institut für Qualität und Wirtschaftlichkeit im Gesundheitswesen (IQWiG) [Ixekizumab (plaque psoriasis in children and adolescents) - Addendum to Commission A20-65]
2021 Institut für Qualität und Wirtschaftlichkeit im Gesundheitswesen (IQWiG) [Cannabidiol for the treatment of Dravet syndrome in patients from the age of 2 years - Assessment according to §35a (para. 1., sentence 11) Social Code Book V (expiry of the decision)]
2021 Institut für Qualität und Wirtschaftlichkeit im Gesundheitswesen (IQWiG) [Cannabidiol for the treatment of Lennox-Gastaut syndrome in patients from the age of 2 years - Assessment according to §35a (para. 1., sentence 11) Social Code Book V (expiry of the decision)]
2021 Institut für Qualität und Wirtschaftlichkeit im Gesundheitswesen (IQWiG) [Filgotinib (rheumatoid arthritis) - Benefit assessment according to §35a Social Code Book V]
2021 Institut für Qualität und Wirtschaftlichkeit im Gesundheitswesen (IQWiG) [Evidence report for the S3 guideline on dementia: Structured information on the initial diagnosis]
2021 Institut für Qualität und Wirtschaftlichkeit im Gesundheitswesen (IQWiG) [Indacaterol acetate/glycopyrronium bromide/mometasone furoate (asthma) - Addendum to Commission A20-69]
2021 Institut für Qualität und Wirtschaftlichkeit im Gesundheitswesen (IQWiG) [Nintedanib (interstitial lung disease) - Addendum to Commission A20-71]
2021 Institut für Qualität und Wirtschaftlichkeit im Gesundheitswesen (IQWiG) [Avapritinib (GIST) - Assessment according to §35a (para. 1., sentence 11) Social Code Book V]
2021 Institut für Qualität und Wirtschaftlichkeit im Gesundheitswesen (IQWiG) [Burosumab (X-linked hypophosphataemia) - Assessment according to §35a (para. 1., sentence 11) Social Code Book V]
2021 Institut für Qualität und Wirtschaftlichkeit im Gesundheitswesen (IQWiG) [Endoscopic thermal ablation of the duodenal mucosa in type 2 diabetes - Assessment according to §137h Social Code Book V]
2021 Institut für Qualität und Wirtschaftlichkeit im Gesundheitswesen (IQWiG) [Irreversible electroporation for chronic bronchitis - Assessment according to §137h Social Code Book V]
2021 Institut für Qualität und Wirtschaftlichkeit im Gesundheitswesen (IQWiG) [Bempedoic acid/ezetimibe (hypercholesterolaemia) - Benefit assessment according to §35a Social Code Book V]
2021 Institut für Qualität und Wirtschaftlichkeit im Gesundheitswesen (IQWiG) [Semaglutide (type 2 diabetes mellitus) - Benefit assessment according to §35a Social Code Book V (new scientific findings)]
2021 Institut für Qualität und Wirtschaftlichkeit im Gesundheitswesen (IQWiG) [Bempedoic acid (hypercholesterolaemia) - Benefit assessment according to §35a Social Code Book V]
2021 Institut für Qualität und Wirtschaftlichkeit im Gesundheitswesen (IQWiG) [Drug-coated balloon dilation catheter for the transurethral treatment of urethral strictures - Assessment according to §137h Social Code Book V]
2021 Institut für Qualität und Wirtschaftlichkeit im Gesundheitswesen (IQWiG) [Secukinumab (plaque psoriasis in children and adolescents) - Addendum to Commission A20-78]
2021 Institut für Qualität und Wirtschaftlichkeit im Gesundheitswesen (IQWiG) [Evidence report for the S3 guideline on dementia: Technical support systems]
2021 Institut für Qualität und Wirtschaftlichkeit im Gesundheitswesen (IQWiG) [Entrectinib (NSCLC) - Addendum to Commission A20-75]
2021 Institut für Qualität und Wirtschaftlichkeit im Gesundheitswesen (IQWiG) [Ivacaftor (cystic fibrosis) - Addendum to Commissions G20-18, G20-20, A20-77, A20-83]
2021 Institut für Qualität und Wirtschaftlichkeit im Gesundheitswesen (IQWiG) [Ivacaftor (combination with ivacaftor/tezacaftor/elexacaftor; cystic fibrosis, 12 years and older, F508del mutation, heterozygous) - Addendum to Commission A20-83]
2021 Institut für Qualität und Wirtschaftlichkeit im Gesundheitswesen (IQWiG) [Secukinumab (psoriatic arthritis) - Addendum to Commission A20-80]
2021 Institut für Qualität und Wirtschaftlichkeit im Gesundheitswesen (IQWiG) [Ivacaftor (combination with ivacaftor/tezacaftor/elexacaftor, cystic fibrosis, 12 years and older, F508del mutation, homozygous) - Addendum to Commission A20-77]