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Year Source Title
2021     Malaysian Health Technology Assessment (MaHTAS) Digital assisted oral & cranio-maxillofacial surgery
2021     The National Health Care Institute (ZIN, Zorginstituut Nederland) GVS advice RZV (Shingrix®) for the prevention of herpes zoster and related post-herpetic neuralgia
2021     Institut für Qualität und Wirtschaftlichkeit im Gesundheitswesen (IQWiG) [Cabozantinib (thyroid carcinoma) - Assessment according to §35a (para. 1., sentence 11) Social Code Book V (expiry of the decision)]
2021     Agència de Qualitat i Avaluació Sanitàries de Catalunya (AQuAS) [Nutritional treatment of patients with chronic obstructive pulmonary disease in a state of malnutrition]
2021     Malaysian Health Technology Assessment (MaHTAS) Platelet rich plasma (PRP), platelet-rich fibrin (PRF) and concentrated growth factor (CGF) for treatment of periodontal disease
2021     The National Health Care Institute (ZIN, Zorginstituut Nederland) GVS advice avatrombopag (Doptelet®) for the treatment of thrombocytopenia
2021     Institut für Qualität und Wirtschaftlichkeit im Gesundheitswesen (IQWiG) [Osimertinib (NSCLC) - Benefit assessment according to §35a Social Code Book V]
2021     Norwegian Institute of Public Health (NIPH) Hydrogel rectal spacer SpaceOAR in prostate cancer radiation therapy - health economic evaluation
2021     The National Health Care Institute (ZIN, Zorginstituut Nederland) GVS advice Vocabria® and Rekambys® for the treatment of HIV-1 infection
2021     Institut für Qualität und Wirtschaftlichkeit im Gesundheitswesen (IQWiG) [Glecaprevir/pibrentasvir (chronic hepatitis C in children) - Benefit assessment according to §35a Social Code Book V]
2021     Agència de Qualitat i Avaluació Sanitàries de Catalunya (AQuAS) [Safety, effectiveness and efficiency of glucometers, gasometers and coagulometers]
2021     NIHR Health Technology Assessment programme Venous access devices for the delivery of long-term chemotherapy: the CAVA three-arm RCT
2021     Norwegian Institute of Public Health (NIPH) Transcatheter aortic valve implantation (TAVI) versus surgical aortic valve replacement (SAVR) for patients with severe aortic stenosis and low surgical risk and across surgical risk groups: a health technology assessment
2021     The National Health Care Institute (ZIN, Zorginstituut Nederland) Package advice isatuximab (Sarclisa®) for the treatment of multiple myeloma
2021     Institut für Qualität und Wirtschaftlichkeit im Gesundheitswesen (IQWiG) [Nivolumab (malignant pleural mesothelioma) - Benefit assessment according to §35a Social Code Book V]
2021     Agència de Qualitat i Avaluació Sanitàries de Catalunya (AQuAS) [Platform to analyse RNA, DNA or proteins as biomarkers in the diagnosis, prognosis and assessment of treatments]
2021     Institut für Qualität und Wirtschaftlichkeit im Gesundheitswesen (IQWiG) [Elotuzumab (multiple myeloma) - Benefit assessment according to §35a Social Code Book V (expiry of the decision)]
2021     Malaysian Health Technology Assessment (MaHTAS) Proton beam therapy for the treatment of cancer - an update
2021     Agència de Qualitat i Avaluació Sanitàries de Catalunya (AQuAS) [Evaluation of the effectiveness of hip and knee implant models used by the Spanish National Health System]
2021     The National Health Care Institute (ZIN, Zorginstituut Nederland) GVS advice ivacaftor (Kalydeco®) extension of further conditions
2021     Institut für Qualität und Wirtschaftlichkeit im Gesundheitswesen (IQWiG) [Brentuximab vedotin (systemic anaplastic large cell lymphoma) - Assessment according to §35a (para. 1., sentence 11) Social Code Book V (expiry of the decision)]
2021     Agència de Qualitat i Avaluació Sanitàries de Catalunya (AQuAS) [Next-generation sequencing (NGS) for molecular diagnosis and the selection of therapeutic targets in oncology]
2021     National Institute for Health and Care Excellence (NICE) Onasemnogene abeparvovec for treating spinal muscular atrophy. NICE highly specialised technologies guidance 15
2021     Scottish Health Technologies Group (SHTG) Minuteful Kidney for home testing of albumin-to-creatine ratio (ACR)
2021     The National Health Care Institute (ZIN, Zorginstituut Nederland) GVS advice dapagliflozin (Forxiga®) extension of further condition
2021     Institut für Qualität und Wirtschaftlichkeit im Gesundheitswesen (IQWiG) [Cabozantinib (renal cell carcinoma) - Addendum to Commission A21-49]
2021     NIHR Health Technology Assessment programme Long limb compared with standard limb Roux-en-Y gastric bypass for type 2 diabetes and obesity: the LONG LIMB RCT
2021     Scottish Health Technologies Group (SHTG) Chest wall bracing for children and young people with pectus carinatum
2021     The National Health Care Institute (ZIN, Zorginstituut Nederland) Package advice pertuzumab and trastuzumab (Phesgo®) for the treatment of breast cancer
2021     Institut für Qualität und Wirtschaftlichkeit im Gesundheitswesen (IQWiG) [Risdiplam (spinal muscular atrophy) - Benefit assessment according to §35a Social Code Book V]
2021     Agència de Qualitat i Avaluació Sanitàries de Catalunya (AQuAS) [Analysis of the volume-outcome relationship in digestive cancer surgery]
2021     The National Health Care Institute (ZIN, Zorginstituut Nederland) Package advice onasemnogene abeparvovec (Zolgensma®) for the treatment of SMA
2021     Agència de Qualitat i Avaluació Sanitàries de Catalunya (AQuAS) [Femtosecond laser-assisted cataract surgery (FLACS). Effectiveness, security and efficiency assessment]
2021     The National Health Care Institute (ZIN, Zorginstituut Nederland) GVS advice inclisiran (Leqvio®) for the treatment of hypercholesterolemia
2021     Institut für Qualität und Wirtschaftlichkeit im Gesundheitswesen (IQWiG) [Self-application of an active motion splint within the treatment of ankle fractures]
2021     Agency for Healthcare Research and Quality (AHRQ) Automated-entry patient-generated health data for chronic conditions: the evidence on health outcomes
2021     The National Health Care Institute (ZIN, Zorginstituut Nederland) Advice on the clustering of combination products and ghost clusters in GVS
2021     Institut für Qualität und Wirtschaftlichkeit im Gesundheitswesen (IQWiG) [Satralizumab (neuromyelitis optica spectrum disorders) - Assessment according to §35a (para. 1., sentence 11) Social Code Book V]
2021     Agency for Healthcare Research and Quality (AHRQ) Breast reconstruction after mastectomy
2021     The National Health Care Institute (ZIN, Zorginstituut Nederland) GVS advice elexacaftor/tezacaftor/ivacaftor (Kaftrio®) in combination with ivacaftor (Kalydeco®)
2021     Institut für Qualität und Wirtschaftlichkeit im Gesundheitswesen (IQWiG) [Empagliflozin (heart failure) - Benefit assessment according to §35a Social Code Book V]
2021     The National Health Care Institute (ZIN, Zorginstituut Nederland) GVS assessment of trientine dihydrochloride (Cufence®) for the treatment of Wilson’s disease
2021     Institut für Qualität und Wirtschaftlichkeit im Gesundheitswesen (IQWiG) [Tralokinumab (atopic dermatitis) - Benefit assessment according to §35a Social Code Book V]
2021     Agency for Healthcare Research and Quality (AHRQ) Care coordination and care plans for transitions across care settings
2021     The National Health Care Institute (ZIN, Zorginstituut Nederland) GVS assessment of crisaborole (Staquis®) for the treatment of atopic dermatitis
2021     Institut für Qualität und Wirtschaftlichkeit im Gesundheitswesen (IQWiG) [Angiotensin II acetate (hypotension) - Benefit assessment according to §35a Social Code Book V]
2021     Basque Office for Health Technology Assessment (OSTEBA) [Efficacy of high flow oxygen therapy for the treatment of respiratory distress in children]
2021     The National Health Care Institute (ZIN, Zorginstituut Nederland) GVS assessment of rivaroxaban (Xarelto®) for the treatment of VTE and prevention of VTE recurrence in children
2021     Institut für Qualität und Wirtschaftlichkeit im Gesundheitswesen (IQWiG) [Onasemnogene abeparvovec (spinal muscular atrophy) - Benefit assessment according to §35a Social Code Book V - Addendum]
2021     Agency for Healthcare Research and Quality (AHRQ) Cervical ripening in the outpatient setting
2021     The National Health Care Institute (ZIN, Zorginstituut Nederland) Advice on a potential candidate for conditional inclusion of entrectinib (Rozlytrek®) for solid tumours with NTRK gene fusion
2021     Institut für Qualität und Wirtschaftlichkeit im Gesundheitswesen (IQWiG) [Relationship between volume of services and quality of treatment outcome for complex procedures of the pancreas - Rapid Report]
2021     Institut für Qualität und Wirtschaftlichkeit im Gesundheitswesen (IQWiG) [Isatuximab (multiple myeloma after >= 1 prior therapy, combination with carfilzomib und dexamethasone) - Benefit assessment according to §35a Social Code Book V - Addendum]
2021     National Institute for Health and Care Excellence (NICE) Givosiran for treating acute hepatic porphyria. NICE highly specialised technologies guidance 16
2021     The National Health Care Institute (ZIN, Zorginstituut Nederland) Advice on a potential candidate for conditional inclusion of larotrectinib (Vitrakvi®) for solid tumours with NTRK gene fusion
2021     Institut für Qualität und Wirtschaftlichkeit im Gesundheitswesen (IQWiG) [Isatuximab (multiple myeloma after >= 2 prior therapies, combination with pomalidomide and dexamethasone) - Benefit assessment according to §35a Social Code Book V - Addendum]
2021     National Institute for Health and Care Excellence (NICE) Metreleptin for treating lipodystrophy. NICE highly specialised technologies guidance 14
2021     The National Health Care Institute (ZIN, Zorginstituut Nederland) GVS assessment of 13-valent pneumococcal conjugate vaccine (Prevenar13®) for medical high-risk groups
2021     Institut für Qualität und Wirtschaftlichkeit im Gesundheitswesen (IQWiG) [Cognitive behavioural therapy for insomnia - Evidence report for the S3 guideline on non-restorative sleep/sleep disorders - Insomnia in adults]
2021     Health Information and Quality Authority (HIQA) Systematic review of cost-effectiveness – management of chronic obstructive pulmonary disease in adults
2021     Austrian Institute for Health Technology Assessment (AIHTA) The economic and societal dimension of parental mental illness. Part 1: systematic review. Part II: economic evaluation framework
2021     The National Health Care Institute (ZIN, Zorginstituut Nederland) GVS assessment of Brimonidine Stulln 2mg/ml eye drop solution for decrease of increased intraocular pressure (IOP) in patients with open-angle glaucoma or ocular hypertension
2021     Institut für Qualität und Wirtschaftlichkeit im Gesundheitswesen (IQWiG) [Blinatumomab (acute lymphoblastic leukaemia, Ph-, CD19+, children aged 1 to 18 years) - Assessment according to §35a (para. 1., sentence 11) Social Code Book V]
2021     Health Information and Quality Authority (HIQA) Budget impact analysis – management of chronic obstructive pulmonary disease in adults
2021     Austrian Institute for Health Technology Assessment (AIHTA) ≥ 12 month follow-up of patients with spinal muscular atrophy (SMA) treated with Spinraza®, Zolgensma® or combination therapies
2021     The National Health Care Institute (ZIN, Zorginstituut Nederland) GVS assessment of formoterol/ glycopyrronium/ budesonide (Trixeo® aerosphere)
2021     Institut für Qualität und Wirtschaftlichkeit im Gesundheitswesen (IQWiG) [Atezolizumab (NSCLC; first line) - Benefit assessment according to §35a Social Code Book V - Addendum]
2021     The National Health Care Institute (ZIN, Zorginstituut Nederland) GVS assessment of sodium zirconium cyclosilicate (Lokelma®) for the treatment of hyperkalemia
2021     Institut für Qualität und Wirtschaftlichkeit im Gesundheitswesen (IQWiG) [Cemiplimab (basal cell carcinoma) - Benefit assessment according to §35a Social Code Book V]
2021     Agency for Healthcare Research and Quality (AHRQ) Disparities and barriers to pediatric cancer survivorship care
2021     NIHR Health Technology Assessment programme POSNOC-POsitive Sentinel NOde: adjuvant therapy alone versus adjuvant therapy plus Clearance or axillary radiotherapy: a randomised controlled trial of axillary treatment in women with early-stage breast cancer who have metastases in one or two sentinel nodes
2021     The National Health Care Institute (ZIN, Zorginstituut Nederland) Package advice multiple myeloma
2021     Institut für Qualität und Wirtschaftlichkeit im Gesundheitswesen (IQWiG) [Teriflunomide (multiple sclerosis) - Benefit assessment according to §35a Social Code Book V]
2021     Health Information and Quality Authority (HIQA) Budget impact analysis – National Clinical Guideline. Unexpected intraoperative life threatening haemorrhage guideline
2021     The National Health Care Institute (ZIN, Zorginstituut Nederland) GVS assessment of opicapone (Ongentys®) for the treatment of Parkinson's disease
2021     Institut für Qualität und Wirtschaftlichkeit im Gesundheitswesen (IQWiG) [Daratumumab (multiple myeloma) - Benefit assessment according to §35a Social Code Book V]
2021     Health Information and Quality Authority (HIQA) Budget impact analysis – stop smoking
2021     Institute for Clinical Effectiveness and Health Policy (IECS) [Equine immunoglobulin F(ab’)2 fragments (hyperimmune equine serum) for COVID-19]
2021     The National Health Care Institute (ZIN, Zorginstituut Nederland) GVS assessment of givosiran (Givlaari®) for the treatment of acute hepatic porphyria
2021     Institut für Qualität und Wirtschaftlichkeit im Gesundheitswesen (IQWiG) [Daratumumab (systemic light chain amyloidosis) - Benefit assessment according to §35a Social Code Book V]
2021     Institut für Qualität und Wirtschaftlichkeit im Gesundheitswesen (IQWiG) [Acalabrutinib (pretreated chronic lymphocytic leukaemia) - Second Addendum to Commission A20-105]
2021     NIHR Health Technology Assessment programme Primary trabeculectomy versus primary glaucoma eye drops for newly diagnosed advanced glaucoma: TAGS RCT
2021     Institute for Clinical Effectiveness and Health Policy (IECS) [Ivermectin for COVID-19]
2021     The National Health Care Institute (ZIN, Zorginstituut Nederland) GVS assessment oxybutynin intravesical solution (Vesolox®)
2021     Institut für Qualität und Wirtschaftlichkeit im Gesundheitswesen (IQWiG) [Cenobamate (epilepsy) - Addendum to Commission A21-78]
2021     Malaysian Health Technology Assessment (MaHTAS) Rezūm therapy for management of benign prostatic hyperplasia
2021     Institut für Qualität und Wirtschaftlichkeit im Gesundheitswesen (IQWiG) [Cemiplimab (non-small cell lung cancer) - Benefit assessment according to §35a Social Code Book V]
2021     NIHR Health Technology Assessment programme Sacral nerve stimulation versus the magnetic sphincter augmentation device for adult faecal incontinence: the SaFaRI RCT
2021     Institute for Clinical Effectiveness and Health Policy (IECS) [Flash glucose monitoring system in diabetes mellitus patients]
2021     Agency for Care Effectiveness (ACE) MRI-US fusion targeted biopsy for diagnosis of prostate cancer
2021     The National Health Care Institute (ZIN, Zorginstituut Nederland) GVS advice mexiletine (Namuscla®)
2021     Institut für Qualität und Wirtschaftlichkeit im Gesundheitswesen (IQWiG) [Enzalutamide (prostate cancer) - Addendum to Commission A21-77]
2021     Malaysian Health Technology Assessment (MaHTAS) 5-aminolevulinic acid (5-ALA) for brain tumour surgical procedure
2021     Institut für Qualität und Wirtschaftlichkeit im Gesundheitswesen (IQWiG) [Nivolumab (colorectal cancer) - Benefit assessment according to §35a Social Code Book V]
2021     Institute for Clinical Effectiveness and Health Policy (IECS) [Ketogenic diet in central nervous system tumors]
2021     Agency for Care Effectiveness (ACE) Transcatheter mitral valve leaflet repair for patients with mitral regurgitation
2021     Institut für Qualität und Wirtschaftlichkeit im Gesundheitswesen (IQWiG) [Bosutinib (chronic myeloid leukaemia) - Benefit assessment according to §35a Social Code Book V. Addendum]
2021     Malaysian Health Technology Assessment (MaHTAS) Single dose rifampicin (SDR) as a prophylaxis for leprosy contacts
2021     Institut für Qualität und Wirtschaftlichkeit im Gesundheitswesen (IQWiG) [Internet- or mobile-based cognitive behavioral therapy for insomnia - Evidence report for the S3 guideline on non-restorative sleep/sleep disorders - Insomnia in adults]
2021     Institute for Clinical Effectiveness and Health Policy (IECS) [Teduglutide in short bowel syndrome]