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Year Source Title
2011     NIHR Horizon Scanning Centre (NIHR HSC) Sorafenib (Nexavar) in combination with capecitabine for HER2-negative locally advanced or metastatic breast cancer - second line
2013     NIHR Horizon Scanning Centre (NIHR HSC) Vedolizumab for ulcerative colitis – second or subsequent line
2015     NIHR Horizon Scanning Centre (NIHR HSC) Palbociclib for advanced or metastatic, oestrogen-receptor positive, HER2-negative, recurrent breast cancer – second line
2016     NIHR Horizon Scanning Centre (NIHR HSC) Teduglutide (Revestive) - short bowel syndrome: in paediatric patients aged 1-17 years who are dependent on parenteral nutrition
2008     NIHR Horizon Scanning Centre (NIHR HSC) Decitabine (Dacogen) for myelodysplastic syndrome
2011     NIHR Horizon Scanning Centre (NIHR HSC) Exenatide (Byetta) for type 2 diabetes mellitus - in combination with basal insulin
2013     NIHR Horizon Scanning Centre (NIHR HSC) Vedolizumab for Crohn's disease – second or subsequent line
2016     NIHR Horizon Scanning Centre (NIHR HSC) Begelomab (Begesand) - graft versus host disease: acute; steroid resistant – second line
2008     NIHR Horizon Scanning Centre (NIHR HSC) Cladribine (Movectro) for multiple sclerosis; relapsing-remitting
2011     NIHR Horizon Scanning Centre (NIHR HSC) Aganirsen for pathological corneal neovascularisation
2013     NIHR Horizon Scanning Centre (NIHR HSC) Ruxolitinib (Jakavi) for polycythaemia vera – second line
2015     NIHR Horizon Scanning Centre (NIHR HSC) Vandetanib (Caprelsa) for locally advanced or metastatic differentiated thyroid cancer – second line
2016     NIHR Horizon Scanning Centre (NIHR HSC) Caplacizumab-Thrombotic thrombocytopenic purpura: acquired; acute phase – adjunctive therapy
2008     NIHR Horizon Scanning Centre (NIHR HSC) Capecitabine (Xeloda) in combination with docetaxel for adjuvant therapy in breast cancer
2011     NIHR Horizon Scanning Centre (NIHR HSC) Idebenone (Catena) for leber's hereditary optic neuropathy - first line
2013     NIHR Horizon Scanning Centre (NIHR HSC) Masitinib for mastocytosis – second or subsequent line
2015     NIHR Horizon Scanning Centre (NIHR HSC) Vemurafenib (Zelboraf) for metastatic BRAF V600 mutation positive melanoma in children and adolescents
2016     NIHR Horizon Scanning Centre (NIHR HSC) Relebactam with imipenem and cilastatin - multi-drug resistant or carbapenem resistant Gram-negative infections
2008     NIHR Horizon Scanning Centre (NIHR HSC) Amibegron (SR-58611) for depression
2011     NIHR Horizon Scanning Centre (NIHR HSC) Ranibizumab (Lucentis) for visual impairment due to choroidal neovascularisation (CNV) secondary to pathological myopia - first line
2013     NIHR Horizon Scanning Centre (NIHR HSC) Monarch™ External Trigeminal Nerve Stimulation (eTNS™) System for depression
2015     NIHR Horizon Scanning Centre (NIHR HSC) GS-6615 for long QT-3 syndrome
2016     NIHR Horizon Scanning Centre (NIHR HSC) Autologous haematopoietic stem cell transplantation - multiple sclerosis: relapsing remitting – second line
2007     NIHR Horizon Scanning Centre (NIHR HSC) Golimumab (CNTO-148) for ankylosing spondylitis
2011     NIHR Horizon Scanning Centre (NIHR HSC) Defibrotide (Defitelio) for hepatic veno-occlusive disease in haematopoietic stem cell transplantation - first line
2013     NIHR Horizon Scanning Centre (NIHR HSC) COGNISION™ for neurological disorders, including dementia
2015     NIHR Horizon Scanning Centre (NIHR HSC) Holoclar for the treatment of limbal stem cell deficiency due to ocular burns
2016     NIHR Horizon Scanning Centre (NIHR HSC) Low dose desmopressin acetate (Noqdirna) - nocturia: idiopathic nocturnal polyuria; symptomatic; in adults – as sole agent or as a combination treatment
2008     NIHR Horizon Scanning Centre (NIHR HSC) ABT-874 for moderate-to-severe chronic plaque psoriasis
2011     NIHR Horizon Scanning Centre (NIHR HSC) Certolizumab pegol (Cimzia) for active ankylosing spondylitis (AS) - second or third line; after intolerance or inadequate response to at least one non-steroidal anti-inflammatory drug (NSAID)
2013     NIHR Horizon Scanning Centre (NIHR HSC) Monarch™ External Trigeminal Nerve Stimulation (eTNS™) System for epilepsy
2015     NIHR Horizon Scanning Centre (NIHR HSC) Midodrine (Bramox) for orthostatic hypotension
2016     NIHR Horizon Scanning Centre (NIHR HSC) Dupilumab - atopic dermatitis: moderate to severe; inadequate response to treatment with topical medications or for whom topical treatments are otherwise medically inadvisable – second line
2008     NIHR Horizon Scanning Centre (NIHR HSC) Vorinostat (Zolinza) for cutaneous T-cell lymphoma - second line
2011     NIHR Horizon Scanning Centre (NIHR HSC) Denosumab (Prolia) for osteoporosis in men
2013     NIHR Horizon Scanning Centre (NIHR HSC) ExAblate® Neuro MR guided focused ultrasound for Parkinson's disease, essential tremor and neuropathic pain
2015     NIHR Horizon Scanning Centre (NIHR HSC) Tenofovir alafenamide monotherapy for hepatitis B
2008     NIHR Horizon Scanning Centre (NIHR HSC) Pemetrexed disodium (Alimta) monotherapy as maintenance therapy for non-small cell lung cancer
2011     NIHR Horizon Scanning Centre (NIHR HSC) Laquinimod for multiple sclerosis: relapsing-remitting - first or second line.
2012     NIHR Horizon Scanning Centre (NIHR HSC) UPDATED: RhinoChill® intranasal cooling device for protective cooling the brain after a cerebral ischaemic event
2013     NIHR Horizon Scanning Centre (NIHR HSC) NTrainer® for developing non-nutritive sucking in premature and newborn infants
2015     NIHR Horizon Scanning Centre (NIHR HSC) Baricitinib for moderate to severe rheumatoid arthritis
2011     NIHR Horizon Scanning Centre (NIHR HSC) Teriflunomide for relapsing multiple sclerosis (MS) - first line
2012     NIHR Horizon Scanning Centre (NIHR HSC) Denosumab (Xgeva) for recurrent or unresectable giant cell tumour of the bone – first or second line
2013     NIHR Horizon Scanning Centre (NIHR HSC) Inspire® Upper Airway Stimulation System for obstructive sleep apnoea
2015     NIHR Horizon Scanning Centre (NIHR HSC) Certolizumab (Cimzia) for early rheumatoid arthritis – first line
2011     NIHR Horizon Scanning Centre (NIHR HSC) Eculizumab (Soliris) for atypical haemolytic uraemic syndrome - first line
2012     NIHR Horizon Scanning Centre (NIHR HSC) Trastuzumab (Herceptin) for HER2 positive early breast cancer – two year regimen
2015     NIHR Horizon Scanning Centre (NIHR HSC) Tofacitinib for psoriatic arthritis – second or subsequent line
2011     NIHR Horizon Scanning Centre (NIHR HSC) Indacaterol/glycopyrronium (QVA-149) for chronic obstructive pulmonary disease
2012     NIHR Horizon Scanning Centre (NIHR HSC) Palifosfamide tromethamine (Zymafos) for advanced soft tissue sarcoma – first line
2015     NIHR Horizon Scanning Centre (NIHR HSC) Patiromer for hyperkalaemia – first line
2012     NIHR Horizon Scanning Centre (NIHR HSC) Emepepimut-S (Stimuvax) for non-small cell lung cancer – maintenance therapy
2015     NIHR Horizon Scanning Centre (NIHR HSC) Alectinib for advanced ALK-positive, non-small cell lung cancer – first line
2007     NIHR Horizon Scanning Centre (NIHR HSC) Xaliproden (Xalprila) for Alzheimer's disease: horizon scanning technology briefing
2012     NIHR Horizon Scanning Centre (NIHR HSC) Elacytarabine for relapsed or refractory acute myeloid leukaemia – second or third line
2015     NIHR Horizon Scanning Centre (NIHR HSC) Alectinib for locally advanced or metastatic ALK-positive, non-small cell lung cancer following failure of crizotinib
2007     NIHR Horizon Scanning Centre (NIHR HSC) Tolvaptan for heart failure (NYHA): horizon scanning technology briefing
2012     NIHR Horizon Scanning Centre (NIHR HSC) Axitinib (Inlyta) for advanced and/or metastatic renal cell carcinoma – first line
2015     NIHR Horizon Scanning Centre (NIHR HSC) Atezolizumab for locally advanced or metastatic non-small cell lung cancer – second line
2007     NIHR Horizon Scanning Centre (NIHR HSC) Tenofovir disoproxil fumarate for hepatitis B: horizon scanning technology briefing
2012     NIHR Horizon Scanning Centre (NIHR HSC) Serelaxin for acute decompensated heart failure – in addition to IV diuretics
2015     NIHR Horizon Scanning Centre (NIHR HSC) Bavituximab for advanced non-small cell lung cancer – second line in combination with docetaxel
2007     NIHR Horizon Scanning Centre (NIHR HSC) Temozolomide (Temodal) for advanced metastatic melanoma: horizon scanning technology briefing
2012     NIHR Horizon Scanning Centre (NIHR HSC) H-FABP immunoturbimetric assay with troponin testing for the assessment of heart-related chest pain
2015     NIHR Horizon Scanning Centre (NIHR HSC) Bevacizumab (Avastin) with erlotinib (Tarceva) for EGFR positive, advanced or metastatic non-small cell lung cancer – first line
2007     NIHR Horizon Scanning Centre (NIHR HSC) Tap water home haemodialysis systems for end stage renal failure: horizon scanning technology briefing
2012     NIHR Horizon Scanning Centre (NIHR HSC) AIGISRx® antibacterial envelope for preventing infection in implanted cardiac devices
2015     NIHR Horizon Scanning Centre (NIHR HSC) Dabrafenib (Tafinlar) and trametinib (Mekinist) combination therapy for metastatic BRAF V600E positive non-small cell lung cancer
2001     NIHR Horizon Scanning Centre (NIHR HSC) New coronary revascularisation techniques - horizon scanning review
2007     NIHR Horizon Scanning Centre (NIHR HSC) Sorafenib (Nexavar) for hepatocellular carcinoma: horizon scanning technology briefing
2012     NIHR Horizon Scanning Centre (NIHR HSC) UPDATED: SoundBite™ hearing system
2015     NIHR Horizon Scanning Centre (NIHR HSC) Daratumumab monotherapy for relapsed and refractory multiple myeloma
2016     NIHR Horizon Scanning Centre (NIHR HSC) Everolimus (Afinitor) for diffuse large B-cell lymphoma – maintenance therapy
2001     NIHR Horizon Scanning Centre (NIHR HSC) Imaging in coronary heart disease - horizon scanning review
2002     NIHR Horizon Scanning Centre (NIHR HSC) Adefovir dipivoxil for chronic hepatitis B - horizon scanning review
2007     NIHR Horizon Scanning Centre (NIHR HSC) Serum procalcitonin (PCT) as a marker of bacterial lower respiratory tract infection: horizon scanning technology briefing
2012     NIHR Horizon Scanning Centre (NIHR HSC) Femtosecond lasers for cataract surgery
2015     NIHR Horizon Scanning Centre (NIHR HSC) Daratumumab with lenalidomide and dexamethasone for relapsed or refractory multiple myeloma
2016     NIHR Horizon Scanning Centre (NIHR HSC) Dabrafenib (Tafinlar) and trametinib (Mekinist) combination therapy for advanced BRAF mutated non-small cell lung cancer
2001     NIHR Horizon Scanning Centre (NIHR HSC) Anakinra for rheumatoid arthritis - horizon scanning review
2002     NIHR Horizon Scanning Centre (NIHR HSC) Anagrelide for essential thrombocythaemia - horizon scanning review
2007     NIHR Horizon Scanning Centre (NIHR HSC) Rivaroxaban (Bay 59-7939) for the prevention of venous thromboembolism (VTE) after major orthopaedic surgery: horizon scanning technology briefing
2012     NIHR Horizon Scanning Centre (NIHR HSC) Sensimed triggerfish® for 24-hour monitoring of changes in intraocular pressure in glaucoma
2015     NIHR Horizon Scanning Centre (NIHR HSC) Gemtuzumab ozogamicin (Mylotarg) with conventional chemotherapy for acute myeloid leukaemia – first line
2016     NIHR Horizon Scanning Centre (NIHR HSC) ADI-PEG 20 for hepatocellular carcinoma – second line
2001     NIHR Horizon Scanning Centre (NIHR HSC) Memantine for Alzheimer's disease and vascular dementia - horizon scanning review
2002     NIHR Horizon Scanning Centre (NIHR HSC) Aripiprazole for schizophrenia and bipolar disorders - horizon scanning review
2007     NIHR Horizon Scanning Centre (NIHR HSC) Prasugrel for acute coronary artery syndrome with percutaneous coronary intervention: horizon scanning technology briefing
2012     NIHR Horizon Scanning Centre (NIHR HSC) UPDATED: Argus II™ retinal prosthesis system for peripheral retinal degeneration
2015     NIHR Horizon Scanning Centre (NIHR HSC) MABp1 (Xilonix) for metastatic colorectal cancer –third line
2016     NIHR Horizon Scanning Centre (NIHR HSC) Heartcel for heart failure in patients at risk of incomplete revascularisation following coronary artery bypass graft
2001     NIHR Horizon Scanning Centre (NIHR HSC) New products for atopic dermatitis - horizon scanning review
2002     NIHR Horizon Scanning Centre (NIHR HSC) Atrasentan for hormone refractory prostate cancer - horizon scanning review
2003     NIHR Horizon Scanning Centre (NIHR HSC) Rubitecan resistant refractory pancreatic cancer - horizon scanning review
2007     NIHR Horizon Scanning Centre (NIHR HSC) Oral topotecan (Hycamtin) for small cell lung cancer: horizon scanning technology briefing
2012     NIHR Horizon Scanning Centre (NIHR HSC) Lubiprostone (Amitiza) for chronic idiopathic constipation
2015     NIHR Horizon Scanning Centre (NIHR HSC) Obinutuzumab (Gazyvaro) for indolent non-Hodgkin lymphoma – first line, in combination with chemotherapy
2016     NIHR Horizon Scanning Centre (NIHR HSC) Furosemide sc2Wear micro-pump patch for oedema in heart failure
2001     NIHR Horizon Scanning Centre (NIHR HSC) Tiotropium for COPD - horizon scanning review