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Year Source Title
2016     NIHR Health Technology Assessment programme The feasibility of a randomised controlled trial of physiotherapy for adults with joint hypermobility syndrome
2016     NIHR Horizon Scanning Centre (NIHR HSC) Ceritinib (Zykadia) - non-small cell lung cancer: locally advanced or metastatic; anaplastic lymphoma kinase (ALK) positive – first line
2016     Institute for Clinical Effectiveness and Health Policy (IECS) Multiplex PCR panels (FilmArray®) to diagnose infections
2016     Institut für Qualität und Wirtschaftlichkeit im Gesundheitswesen (IQWiG) [Measurement and monitoring of pulmonary artery pressure via an implanted sensor for treatment optimization in heart failure]
2016     Institute for Clinical Effectiveness and Health Policy (IECS) Fractional exhaled nitric oxygen in asthma patients
2016     Institut für Qualität und Wirtschaftlichkeit im Gesundheitswesen (IQWiG) [Measurement and monitoring of pulmonary artery pressure via an implanted sensor for treatment optimization in heart failure - Addendum to Commission E15-04]
2016     NIHR Health Technology Assessment programme Financial incentives to improve adherence to antipsychotic maintenance medication in non-adherent patients: a cluster randomised controlled trial
2016     NIHR Horizon Scanning Centre (NIHR HSC) Decitabine (Dacogen) - acute myeloid leukaemia: newly diagnosed de novo or secondary; adult patients of all ages who are not suitable for standard induction chemotherapy
2016     Institute for Clinical Effectiveness and Health Policy (IECS) Extracorporeal shock wave therapy in musculoskeletal disorders
2016     NIHR Health Technology Assessment programme The Diagnosis of Urinary Tract infection in Young children (DUTY): a diagnostic prospective observational study to derive and validate a clinical algorithm for the diagnosis of urinary tract infection in children presenting to primary care with an acute illness
2016     Institute for Clinical Effectiveness and Health Policy (IECS) Botulinum toxin for sialorrhea
2016     NIHR Health Technology Assessment programme CATheter Infections in CHildren (CATCH): a randomised controlled trial and economic evaluation comparing impregnated and standard central venous catheters in children
2016     NIHR Horizon Scanning Centre (NIHR HSC) Pembrolizumab (Keytruda) - colorectal cancer: advanced or metastatic; high-level microsatellite instability – second line
2016     Institute for Clinical Effectiveness and Health Policy (IECS) Magnetic resonance neurography to study peripheral neuropathies
2016     NIHR Health Technology Assessment programme The UK Lung Cancer Screening Trial: a pilot randomised controlled trial of low-dose computed tomography screening for the early detection of lung cancer
2016     NIHR Health Technology Assessment programme OPTIMA prelim: a randomised feasibility study of personalised care in the treatment of women with early breast cancer
2016     NIHR Public Health Research (PHR) programme Change in alcohol outlet density and alcohol-related harm to population health (CHALICE): a comprehensive record-linked database study in Wales
2016     NIHR Horizon Scanning Centre (NIHR HSC) Pembrolizumab (Keytruda) - Hodgkin lymphoma: classical; relapsed or refractory – third and fourth line
2016     Institute for Clinical Effectiveness and Health Policy (IECS) High-dose chemotherapy followed by autologous transplantation of hematopoietic stem cells in patients with recurrent childhood medulloblastoma
2016     NIHR Health Technology Assessment programme EQUATOR Network
2016     NIHR Horizon Scanning Centre (NIHR HSC) Quizartinib - acute myeloid leukaemia: relapsed or refractory; FLT3-internal tandem duplication (ITD) positive – second line
2016     Institute for Clinical Effectiveness and Health Policy (IECS) Cannabinoids for refractory epilepsy treatment
2016     NIHR Health Technology Assessment programme Neuraminidase inhibitors for influenza: a systematic review and meta-analysis of regulatory and mortality data
2016     NIHR Horizon Scanning Centre (NIHR HSC) Ribociclib with tamoxifen and goserelin, or a non-steroidal aromatase inhibitor and goserelin - breast cancer: advanced; hormone-receptor positive, human epidermal growth factor receptor 2 (HER2) negative; premenopausal women – first line
2016     Institute for Clinical Effectiveness and Health Policy (IECS) Percutaneous closure of patent foramen ovale for stroke prevention
2016     NIHR Health Technology Assessment programme Does therapeutic writing help people with long-term conditions? Systematic review, realist synthesis and economic considerations
2016     NIHR Horizon Scanning Centre (NIHR HSC) Sapacitabine - acute myeloid leukaemia: patients ≥70 years of age; not candidates for standard intensive therapy – first line
2016     Institute for Clinical Effectiveness and Health Policy (IECS) Activated charcoal for preoperative localization of thyroid cancer recurrence
2016     NIHR Health Technology Assessment programme Prediction of risk of recurrence of venous thromboembolism following treatment for a first unprovoked venous thromboembolism: systematic review, prognostic model and clinical decision rule, and economic evaluation
2016     NIHR Horizon Scanning Centre (NIHR HSC) Zoptarelin doxorubicin - endometrial cancer: locally advanced, recurrent or metastatic – second line
2016     Institute for Clinical Effectiveness and Health Policy (IECS) Cryoablation for the treatment of kidney tumors
2016     NIHR Horizon Scanning Centre (NIHR HSC) Volanesorsen - familial chylomicronemia syndrome – first line
2016     Institute for Clinical Effectiveness and Health Policy (IECS) Rituximab biosimilars
2016     NIHR Health Technology Assessment programme A systematic review, evidence synthesis and meta-analysis of quantitative and qualitative studies evaluating the clinical effectiveness, the cost-effectiveness, safety and acceptability of interventions to prevent postnatal depression
2016     NIHR Horizon Scanning Centre (NIHR HSC) Simtuzumab - liver fibrosis secondary to non-alcoholic steatohepatitis or primary sclerosing cholangitis
2016     Institute for Clinical Effectiveness and Health Policy (IECS) Biomedical treatment for autism spectrum disorders
2016     Canadian Agency for Drugs and Technologies in Health (CADTH) Anti-vascular endothelial growth factor drugs for the treatment of retinal conditions
2016     NIHR Horizon Scanning Centre (NIHR HSC) Teduglutide (Revestive) - short bowel syndrome: in paediatric patients aged 1-17 years who are dependent on parenteral nutrition
2016     Institute for Clinical Effectiveness and Health Policy (IECS) Use of anti-neuronal antibodies to diagnose paraneoplastic neurological syndromes
2016     NIHR Health Technology Assessment programme A randomised controlled trial of the probiotic Bifidobacterium breve BBG-001 in preterm babies to prevent sepsis, necrotising enterocolitis and death: the Probiotics in Preterm infantS (PiPS) trial
2016     NIHR Health Services and Delivery Research programme Management by geographical area or management specialised by disorder? A mixed-methods evaluation of the effects of an organisational intervention on secondary mental health care for common mental disorder
2016     NIHR Horizon Scanning Centre (NIHR HSC) Begelomab (Begesand) - graft versus host disease: acute; steroid resistant – second line
2016     Institute for Clinical Effectiveness and Health Policy (IECS) Eye tracking speech-generating devices in disorders involving language, speech and motor skills
2016     NIHR Health Technology Assessment programme An observational study to assess if automated diabetic retinopathy image assessment software can replace one or more steps of manual imaging grading and to determine their cost-effectiveness
2016     NIHR Horizon Scanning Centre (NIHR HSC) Caplacizumab-Thrombotic thrombocytopenic purpura: acquired; acute phase – adjunctive therapy
2016     Institute for Clinical Effectiveness and Health Policy (IECS) Riociguat for the treatment of pulmonary hypertension
2016     NIHR Health Technology Assessment programme BREATHER (PENTA 16) short-cycle therapy (SCT) (5 days on/2 days off) in young people with chronic human immunodeficiency virus infection: an open, randomised, parallel-group Phase II/III trial
2016     Agency for Healthcare Research and Quality (AHRQ) Noninvasive testing for coronary artery disease
2016     NIHR Horizon Scanning Centre (NIHR HSC) Relebactam with imipenem and cilastatin - multi-drug resistant or carbapenem resistant Gram-negative infections
2016     Institute for Clinical Effectiveness and Health Policy (IECS) Radio-223 (Xofigo®) for the treatment of patients with metastatic cancer
2016     Agency for Healthcare Research and Quality (AHRQ) Improving cultural competence to reduce health disparities
2016     NIHR Horizon Scanning Centre (NIHR HSC) Autologous haematopoietic stem cell transplantation - multiple sclerosis: relapsing remitting – second line
2016     Institute for Clinical Effectiveness and Health Policy (IECS) Single-use negative pressure wound therapy for chronic and acute wounds
2016     Agency for Healthcare Research and Quality (AHRQ) Early diagnosis, prevention, and treatment of Clostridium difficile: update
2016     NIHR Horizon Scanning Centre (NIHR HSC) Low dose desmopressin acetate (Noqdirna) - nocturia: idiopathic nocturnal polyuria; symptomatic; in adults – as sole agent or as a combination treatment
2016     Institute for Clinical Effectiveness and Health Policy (IECS) Stem cell therapy in heart failure prevention and progress
2016     NIHR Health Technology Assessment programme An Occupational Therapy intervention for residents with stroke-related disabilities in UK Care Homes (OTCH): cluster randomised controlled trial with economic evaluation
2016     Agency for Healthcare Research and Quality (AHRQ) Data linkage strategies to advance youth suicide prevention
2016     NIHR Horizon Scanning Centre (NIHR HSC) Dupilumab - atopic dermatitis: moderate to severe; inadequate response to treatment with topical medications or for whom topical treatments are otherwise medically inadvisable – second line
2016     Institute for Clinical Effectiveness and Health Policy (IECS) Nivolumab for the treatment of non-small cell lung cancer
2016     NIHR Health Technology Assessment programme Antidepressant Controlled Trial For Negative Symptoms In Schizophrenia (ACTIONS): a double-blind, placebo-controlled, randomised clinical trial
2016     Agency for Healthcare Research and Quality (AHRQ) Nonpharmacologic interventions for agitation and aggression in dementia
2016     Institute for Clinical Effectiveness and Health Policy (IECS) Nivolumab in advanced melanoma treament
2016     Agency for Healthcare Research and Quality (AHRQ) Treatments for fecal incontinence
2016     Institute for Clinical Effectiveness and Health Policy (IECS) Glifing method to treat dyslexia
2016     Basque Office for Health Technology Assessment (OSTEBA) [Design and validation of a screening tool for evaluating the health impact of regional policies]
2016     Agency for Healthcare Research and Quality (AHRQ) Treatment strategies for patients with lower extremity chronic venous disease (LECVD)
2016     Institute for Clinical Effectiveness and Health Policy (IECS) Magnetic resonance imaging with tractography for brain white matter diseases
2016     Basque Office for Health Technology Assessment (OSTEBA) [Evaluation of care times for the main cancer sites: colon/rectum, lung, breast and prostate]
2016     NIHR Health Technology Assessment programme The HubBLe Trial: haemorrhoidal artery ligation (HAL) versus rubber band ligation (RBL) for symptomatic second- and third-degree haemorrhoids: a multicentre randomised controlled trial and health-economic evaluation
2016     Agency for Healthcare Research and Quality (AHRQ) Retinal prostheses in the Medicare population
2016     Institute for Clinical Effectiveness and Health Policy (IECS) Percutaneous epidural neurolysis and endoscopic neurolysis for the treatment of chronic low back pain
2016     Basque Office for Health Technology Assessment (OSTEBA) [Impact of the implementation of EFQM in Osakidetza]
2016     Agency for Healthcare Research and Quality (AHRQ) Renal denervation in the Medicare Population
2016     Institute for Clinical Effectiveness and Health Policy (IECS) Trigeminal nerve stimulation to treat neuralgia
2016     Basque Office for Health Technology Assessment (OSTEBA) [Prevention of Type 2 Diabetes Mellitus in Primary Health Care through healthy lifestyles: care and recommended clinical interventions]
2016     NIHR Health Technology Assessment programme Clinical effectiveness and cost-effectiveness of physiotherapy and occupational therapy versus no therapy in mild to moderate Parkinson s disease: a large pragmatic randomised controlled trial (PD REHAB)
2016     NIHR Health Technology Assessment programme Tackling obesity in areas of high social deprivation: clinical effectiveness and cost-effectiveness of a task-based weight management group programme a randomised controlled trial and economic evaluation
2016     NIHR Health Technology Assessment programme Adalimumab, etanercept, infliximab, certolizumab pegol, golimumab, tocilizumab and abatacept for the treatment of rheumatoid arthritis not previously treated with disease-modifying antirheumatic drugs and after the failure of conventional disease-modifying antirheumatic drugs only: systematic review and economic evaluation
2016     NIHR Health Technology Assessment programme Accurate diagnosis of latent tuberculosis in children, people who are immunocompromised or at risk from immunosuppression and recent arrivals from countries with a high incidence of tuberculosis: systematic review and economic evaluation
2016     Institut national d'excellence en sante et en services sociaux (INESSS) [Levels of care: norms and quality standards]
2016     Institute for Clinical Effectiveness and Health Policy (IECS) Pembrolizumab for the treatment of advanced melanoma
2016     Basque Office for Health Technology Assessment (OSTEBA) [Assessment of factors related to the pharmaceutical expenditure in Primary Care, and prescription quality in chronic diseases]
2016     NIHR Health Technology Assessment programme The Role of Ultrasound Compared to Biopsy of Temporal Arteries in the Diagnosis and Treatment of Giant Cell Arteritis (TABUL): a diagnostic accuracy and cost-effectiveness study
2016     Institut national d'excellence en sante et en services sociaux (INESSS) [Localized prostate cancer: effectiveness and safety of treatment options]
2016     NIHR Health Technology Assessment programme The identification and treatment of women with hyperglycaemia in pregnancy: an analysis of individual participant data, systematic reviews, meta-analyses and an economic evaluation
2016     Basque Office for Health Technology Assessment (OSTEBA) [Impact of the implementation of a population-based cervical cancer screening program based on European recommendations (test/interval) with regard to the current situation]
2016     NIHR Health Technology Assessment programme A multicentre, randomised controlled trial comparing the clinical effectiveness and cost-effectiveness of early nutritional support via the parenteral versus the enteral route in critically ill patients (CALORIES)
2016     Institut national d'excellence en sante et en services sociaux (INESSS) [Use of the Oncotype DX® test for therapeutic decision-making in the context of treating invasive breast cancer]
2016     NIHR Health Technology Assessment programme Placental growth factor (alone or in combination with soluble fms-like tyrosine kinase 1) as an aid to the assessment of women with suspected pre-eclampsia: systematic review and economic analysis
2016     Basque Office for Health Technology Assessment (OSTEBA) [An image-guided system for liver surgery (CAScination)]
2016     Institut für Qualität und Wirtschaftlichkeit im Gesundheitswesen (IQWiG) [Aclidinium bromide - Benefit assessment according to §35a Social Code Book V]
2016     Institut national d'excellence en sante et en services sociaux (INESSS) [Tonsil surgery: comparison of intracapsular dissections and extracapsular dissections and dentification of children at risk for hemorrhage]
2016     NIHR Health Technology Assessment programme Orthotic management of instability of the knee related to neuromuscular and central nervous system disorders: systematic review, qualitative study, survey and costing analysis
2016     Health Quality Ontario (HQO) Levonorgestrel-releasing intrauterine sSystem (52 mg) for idiopathic heavy menstrual bleeding: a health technology assessment
2016     Basque Office for Health Technology Assessment (OSTEBA) [Economic analysis of peripherally inserted central venous catheters (PICC), inserted by nursing staff, in cancer and hematological patients]
2016     Institut für Qualität und Wirtschaftlichkeit im Gesundheitswesen (IQWiG) [Nivolumab - Addendum to Commission A15-32]
2016     NIHR Health Technology Assessment programme The use of exploratory analyses within the National Institute for Health and Care Excellence single technology appraisal process: an evaluation and qualitative analysis
2016     NIHR Public Health Research (PHR) programme Implications for public health research of models and theories of disability: a scoping study and evidence synthesis
2016     Health Quality Ontario (HQO) Transcatheter aortic valve implantation for treatment of aortic valve stenosis: a health technology assessment