Evaluation of droplet dispersion during non-invasive ventilation, oxygen therapy, nebuliser treatment and chest physiotherapy in clinical practice: implications for management of pandemic influenza and other airborne infections.

Simonds AK, Hanak A, Chatwin M, Morrell MJ, Hall A, Parker KH, Siggers JH, Dickinson RJ
Record ID 32010001170
English
Authors' recommendations: Non-invasive ventilation and chest physiotherapy are droplet (not aerosol)-generating procedures, producing droplets of > 10 µm in size. Due to their large mass, most fall out on to local surfaces within 1 m. The only device producing an aerosol was the nebuliser and the output profile is consistent with nebuliser characteristics rather than dissemination of large droplets from patients. These findings suggest that health-care workers providing NIV and chest physiotherapy working within 1 m of an infected patient should have a higher level of respiratory protection, but that infection control measures designed to limit aerosol spread, for example negative-pressure rooms, may have less relevance. The results may have infection control implications for other airborne infections, such as SARS and tuberculosis, as well as for pandemic influenza infection.
Details
Project Status: Completed
Year Published: 2010
English language abstract: An English language summary is available
Publication Type: Not Assigned
Country: England, United Kingdom
MeSH Terms
  • Adolescent
  • Adult
  • Aerosols
  • Aged
  • Aged, 80 and over
  • Case-Control Studies
  • Confidence Intervals
  • Female
  • Influenza A Virus, H1N1 Subtype
  • Male
  • Middle Aged
  • Nebulizers and Vaporizers
  • Pulmonary Disease, Chronic Obstructive
  • Risk
  • Risk Assessment
  • Severe acute respiratory syndrome-related coronavirus
  • Young Adult
  • Disease Outbreaks
  • Influenza, Human
  • Oxygen Inhalation Therapy
  • Physical Therapy Modalities
  • Respiration, Artificial
Contact
Organisation Name: NIHR Health Technology Assessment programme
Contact Address: NIHR Journals Library, National Institute for Health and Care Research, Evaluation, Trials and Studies Coordinating Centre, Alpha House, University of Southampton Science Park, Southampton SO16 7NS, UK
Contact Name: journals.library@nihr.ac.uk
Contact Email: journals.library@nihr.ac.uk
Copyright: 2010 Queen's Printer and Controller of HMSO
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