[Efficacy and safety of nitrous oxide 50% mixed with oxygen in the use as inhalation analgesic during labor]
Ruiz Aragon J, Carmen Beltran Calvo C
Record ID 32010001099
Spanish
Authors' recommendations:
The inhalation administration of nitrous oxide women during childbirth could be an alternative to the interventions commonly used for this purpose. This report assesses the efficacy and safety of nitrous oxide 50% mixed with oxygen in the use as inhalation analgesic during labor. This review has been undertaken to synthesize the clinical evidence available in scientific literature. We found 230 references and after applied inclusion criteria were included four articles. The included studies have several limitations and moderate methodological quality. The results, in terms of efficacy, have the administration of nitrous oxide inhalation as a treatment that produces moderate but satisfactory analgesia in labor. But the degree of analgesia is less than when using other types of analgesics or anesthetics (enflurane, sevoflurane, remifentanil), so their efficacy is lower. The analgesic use for 50% is presented as a safe and has few side effects occurred during delivery. However, it is advisable to control oxygen saturation in women during labor and the administration of a local anesthetic if necessary perform episiotomy. Nitrous oxide is shown as a moderate analgesic activity and safety, to be used as an analgesic 50% inhaled oxygen during labor, so it is considered feasible its possible introduction in daily clinical practice.
Details
Project Status:
Completed
URL for project:
https://www.aetsa.org/publicacion/eficacia-y-seguridad-de-la-utilizacion-del-oxido-nitroso-al-50-como-analgesia-en-el-parto/
Year Published:
2010
URL for published report:
https://www.aetsa.org/download/publicaciones/antiguas/AETSA_P_2010_3_OxidoNitroso.pdf
English language abstract:
An English language summary is available
Publication Type:
Not Assigned
Country:
Spain
MeSH Terms
- Analgesics
- Labor Pain
- Nitrous Oxide
Contact
Organisation Name:
Andalusian Health Technology Assessment Area
Contact Address:
Area de Evaluacion de Tecnologias Sanitarias Sanitarias de Andalucia (AETSA) Avda. Innovación, s/n Edificio Arena 1. Sevilla (Spain) Tel. +34 955 006 309
Contact Name:
aetsa.csalud@juntadeandalucia.es
Contact Email:
aetsa.csalud@juntadeandalucia.es
Copyright:
Andalusian Agency for Health Technology Assessment (AETSA)
This is a bibliographic record of a published health technology assessment from a member of INAHTA or other HTA producer. No evaluation of the quality of this assessment has been made for the HTA database.