PTEN Hamartoma Tumor Syndrome (PHTS)

Record ID 32010001009
English
Authors' objectives:

PTEN Hamartoma Tumor Syndrome (PHTS) encompasses Cowden syndrome (CS), Bannayan-Riley-Ruvalcaba syndrome (BRRS), and Proteus syndrome (PS), which have phenotypic overlap that includes hamartomatous tumors. PHTS has been estimated to affect 1 in 200,000 people worldwide. PHTS is caused by sequence variants in the tumor suppressor phosphatase and tensin homolog (PTEN) gene. PHTS is inherited in an autosomal dominant manner with > 200 pathogenic sequence variants described to date.

Details
Project Status: Completed
URL for project: http://www.hayesinc.com
Year Published: 2010
English language abstract: An English language summary is available
Publication Type: Not Assigned
Country: United States
MeSH Terms
  • PTEN Phosphohydrolase
Contact
Organisation Name: HAYES, Inc.
Contact Address: 157 S. Broad Street, Suite 200, Lansdale, PA 19446, USA. Tel: 215 855 0615; Fax: 215 855 5218
Contact Name: saleinfo@hayesinc.com
Contact Email: saleinfo@hayesinc.com
Copyright: 2010 Winifred S. Hayes, Inc
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