AlloDerm regenerative tissue matrix (LifeCell Corp.) for postmastectomy breast reconstruction
Nearly 80,000 breast cancer patients in the United States undergo breast reconstruction each year after mastectomy. Breasts can be reconstructed with the patient's own skin, fat, and muscle (tissue flaps), with breast implants, or a combination. Breast implants are saline- or silicone-filled prostheses that are inserted under the pectoral (chest) muscle. Successful implant reconstruction depends upon a sufficient quantity of healthy tissue and muscle left behind after mastectomy to cover and support the prosthesis. In some cases, the skin does not cover the entire implant, or the muscles over the implant are too thin to provide adequate support, even after tissue expansion with a temporary implant. Allogeneic grafts, i.e., grafts obtained from cadavers, have been evaluated for their usefulness in providing additional coverage and support during breast reconstruction procedures.
- Mastectomy
- Skin, Artificial
- Mammaplasty