Vaccine effectiveness in pandemic influenza - primary care reporting (VIPER): an observational study to assess the effectiveness of the pandemic influenza A (H1N1)v vaccine
Simpson CR, Ritchie LD, Robertson C, Sheikh A, McMenamin J
Record ID 32010000830
English
Authors' recommendations:
Evidence from swabs submitted from patients in the cohort presenting with influenza-like illness in general practice suggests that the introduction of influenza A (H1N1)v vaccine in Scotland during 2009 was associated with a high degree of protection against influenza A (H1N1)v. In addition, receipt of influenza A (H1N1)v vaccine was associated with a reduction in both admission for cardiac-related conditions and for the combined category of influenza, pneumonia, COPD and cardiac conditions. Policy-makers ought to be encouraged that the VE estimates obtained are comparable to those found for seasonal influenza. Additionally, as the first large-scale demonstration of effectiveness in a UK population, these interim results should help strengthen the evidence base for health-care practitioners involved in distributing influenza A (H1N1)v vaccine in other countries, now that the phased roll-out has been completed in the UK. Influenza A (H1N1)v immunisation in the primary health care setting is both effective and widely acceptable, as evidenced by high uptake rates, and should continue to be a mainstay of disease prevention for at-risk patients. Whether the reduced incidence of severe complications of influenza will persist or a reduction in mortality has occurred will only be apparent when data collected from later in 2010 are analysed.
Details
Project Status:
Completed
URL for project:
http://www.hta.ac.uk/fullmono/mon1434.pdf#nameddest=article05
Year Published:
2010
URL for published report:
http://www.hta.ac.uk/2224
English language abstract:
An English language summary is available
Publication Type:
Not Assigned
Country:
England, United Kingdom
MeSH Terms
- Influenza A Virus, H1N1 Subtype
- Influenza, Human
Contact
Organisation Name:
NIHR Health Technology Assessment programme
Contact Address:
NIHR Journals Library, National Institute for Health and Care Research, Evaluation, Trials and Studies Coordinating Centre, Alpha House, University of Southampton Science Park, Southampton SO16 7NS, UK
Contact Name:
journals.library@nihr.ac.uk
Contact Email:
journals.library@nihr.ac.uk
Copyright:
2010 Queen's Printer and Controller of HMSO
This is a bibliographic record of a published health technology assessment from a member of INAHTA or other HTA producer. No evaluation of the quality of this assessment has been made for the HTA database.