What is the clinical effectiveness and cost-effectiveness of using drugs in treating obese patients in primary care? A systematic review

Ara R, Blake L, Gray L, Hernández M, Crowther M, Dunkley A, Warren F, Jackson R, Rees A, Stevenson M, Abrams K, Cooper N, Davies M, Khunti K, Sutton A
Record ID 32010000307
Authors' objectives: The objective of this research was to evaluate the clinical effectiveness and cost-effectiveness of pharmacological interventions compared with each other and with standard care in obese patients in primary care.
Authors' recommendations: Although orlistat, sibutramine and rimonabant are all effective at reducing weight and body mass index and, compared with placebo, are all cost-effective, both sibutramine and rimonabant have been withdrawn because of safety concerns relating to potential treatment-induced fatal adverse events.
Project Status: Completed
URL for project: http://www.hta.ac.uk/1761
Year Published: 2012
URL for published report: http://www.hta.ac.uk/1761
English language abstract: An English language summary is available
Publication Type: Not Assigned
Country: England, United Kingdom
MeSH Terms
  • Obesity
  • Overweight
  • Primary Health Care
Organisation Name: NIHR Health Technology Assessment programme
Contact Address: NIHR Journals Library, National Institute for Health and Care Research, Evaluation, Trials and Studies Coordinating Centre, Alpha House, University of Southampton Science Park, Southampton SO16 7NS, UK
Contact Name: journals.library@nihr.ac.uk
Contact Email: journals.library@nihr.ac.uk
Copyright: 2012 Queen's Printer and Controller of HMSO
This is a bibliographic record of a published health technology assessment from a member of INAHTA or other HTA producer. No evaluation of the quality of this assessment has been made for the HTA database.