The value of FDG positron emission tomography/computerised tomography (PET/CT) in pre-operative staging of colorectal cancer: a systematic review and economic evaluation
Brush J, Boyd K, Chappell F, Crawford F, Dozier M, Fenwick E, Glanville J, McIntosh H, Renehan A, Weller D, Dunlop M
Record ID 32010000294
English
Authors' objectives:
To conduct a systematic review of the diagnostic accuracy and therapeutic impact of FDG PET/CT for the pre-operative staging of primary, recurrent and metastatic cancer.
To undertake probabilistic decision-analytic modelling (using Monte Carlo simulation).
To conduct a value of information analysis to help inform whether or not there is potential worth in undertaking further research
Authors' recommendations:
Study found insufficient evidence to support the routine use of FDG PET-CT in primary colorectal cancer and only a small amount of evidence supporting its use in the pre-operative staging of recurrent and metastatic colorectal cancer. Economic evaluation showed that FDG PET/CT as an add-on imaging device is cost-effective in the pre-operative staging of recurrent colon, recurrent rectal and metastatic disease but not primary colon or rectal cancers.
Details
Project Status:
Completed
URL for project:
http://www.hta.ac.uk/1812
Year Published:
2011
English language abstract:
An English language summary is available
Publication Type:
Not Assigned
Country:
England, United Kingdom
MeSH Terms
- Colorectal Neoplasms
- Neoplasm Staging
- Positron-Emission Tomography
Contact
Organisation Name:
NIHR Health Technology Assessment programme
Contact Address:
NIHR Journals Library, National Institute for Health and Care Research, Evaluation, Trials and Studies Coordinating Centre, Alpha House, University of Southampton Science Park, Southampton SO16 7NS, UK
Contact Name:
journals.library@nihr.ac.uk
Contact Email:
journals.library@nihr.ac.uk
Copyright:
2011 Queen’s Printer and Controller of HMSO
This is a bibliographic record of a published health technology assessment from a member of INAHTA or other HTA producer. No evaluation of the quality of this assessment has been made for the HTA database.