Influence of reported study design characteristics on intervention effect estimates from randomised controlled trials: combined analysis of meta-epidemiological studies

Savovic J, Jones HE, Altman DG, Harris RJ, Juni P, Pildal J, Als-Nielsen B, Balk EM, Gluud C, Gluud LL, Ioannidis JP, Schulz KF, Beynon R, Welton N, Wood L, Moher D, Deeks JJ, Sterne JA
Record ID 32010000285
English
Authors' recommendations: Specific reported study design characteristics are associated with exaggeration of beneficial intervention effect estimates and increases in between-trial heterogeneity, with these effects being greatest for subjectively assessed outcomes.
Details
Project Status: Completed
Year Published: 2012
URL for published report: http://www.hta.ac.uk/1582
English language abstract: An English language summary is available
Publication Type: Not Assigned
Country: England, United Kingdom
MeSH Terms
  • Benchmarking
  • Evidence-Based Medicine
  • Research Design
Contact
Organisation Name: NIHR Health Technology Assessment programme
Contact Address: NIHR Journals Library, National Institute for Health and Care Research, Evaluation, Trials and Studies Coordinating Centre, Alpha House, University of Southampton Science Park, Southampton SO16 7NS, UK
Contact Name: journals.library@nihr.ac.uk
Contact Email: journals.library@nihr.ac.uk
Copyright: 2012 Queen's Printer and Controller of HMSO
This is a bibliographic record of a published health technology assessment from a member of INAHTA or other HTA producer. No evaluation of the quality of this assessment has been made for the HTA database.