Vitamin K to prevent fractures in older women: a systematic review and economic evaluation

Stevenson M, Lloyd-Jones M, Papaioannou D
Record ID 32009100577
Authors' recommendations: Study found that there is currently great uncertainty over whether vitamin K1 is more cost-effective than alendronate in preventing osteoporotic fractures in postmenopausal women. Expected value of sample information analyses indicate that a head-to-head randomised controlled trial of alendronate and vitamin K1, recruiting 2000 women per arm, would be a cost-effective use of resources
Project Status: Completed
URL for project:
Year Published: 2009
English language abstract: An English language summary is available
Publication Type: Not Assigned
Country: England, United Kingdom
MeSH Terms
  • Aged
  • Aged, 80 and over
  • Cost-Benefit Analysis
  • Female
  • Models, Econometric
  • Quality-Adjusted Life Years
  • Bone Density Conservation Agents
  • Fractures, Bone
  • Osteoporosis, Postmenopausal
  • Vitamin K
  • Vitamin K 1
  • Vitamin K 2
  • Vitamins
Organisation Name: NIHR Health Technology Assessment programme
Contact Address: NIHR Journals Library, National Institute for Health and Care Research, Evaluation, Trials and Studies Coordinating Centre, Alpha House, University of Southampton Science Park, Southampton SO16 7NS, UK
Contact Name:
Contact Email:
Copyright: 2009 Queen’s Printer and Controller of HMSO
This is a bibliographic record of a published health technology assessment from a member of INAHTA or other HTA producer. No evaluation of the quality of this assessment has been made for the HTA database.