Zanamivir, oseltamivir and amantadine for the treatment of influenza (an update review of existing guidance)

Tappenden P, Jackson R, Cooper K, Rees A, Simpson E, Read R, Nicholson K
Record ID 32008100360
English
Authors' objectives:

To evaluate the clinical effectiveness and incremental cost-effectiveness of amantadine, oseltamivir and zanamivir for seasonal and postexposure prophylaxis of influenza.

Authors' recomendations: All three interventions showed some efficacy for seasonal and post-exposure prophylaxis. However, weaknesses and gaps in the clinical evidence base are directly relevant to the interpretation of the health economic model and rendered the use of advanced statistical analyses inappropriate. These data limitations should be borne in mind in interpreting thefindings of the review.
Details
Project Status: Completed
URL for project: http://www.hta.ac.uk/1686
Year Published: 2009
English language abstract: An English language summary is available
Publication Type: Not Assigned
Country: England
MeSH Terms
  • Amantadine
  • Antiviral Agents
  • Influenza, Human
  • Oseltamivir
  • Rimantadine
  • Zanamivir
Contact
Organisation Name: NIHR Health Technology Assessment programme
Contact Address: NIHR Journals Library, National Institute for Health Research, Evaluation, Trials and Studies Coordinating Centre, Alpha House, University of Southampton Science Park, Southampton SO16 7NS, UK
Contact Name: journals.library@nihr.ac.uk
Contact Email: journals.library@nihr.ac.uk
Copyright: 2009 Queen's Printer and Controller of HMSO
This is a bibliographic record of a published health technology assessment from a member of INAHTA or other HTA producer. No evaluation of the quality of this assessment has been made for the HTA database.