Sildenafil: an oral drug for the treatment of male erectile dysfunction

Burls A, Clark W, Gold L, Simpson S
Record ID 31999008503
Authors' objectives:

To assess the effectiveness and cost effectiveness of sildenafil for male erectile dysfunction.

Authors' recommendations: All trials included showed a statistically significant improvement in erectile function in patients using sildenafil compared to placebo. About 75-80% of men show a clinically significant improvement in erectile or sexual function on sildenafil compared to ~25% on placebo. The number needed to treat was ~2. There is wide agreement among urologists, pharmacists and GPs that the primary diagnosis of ED and its treatment with sildenafil can be undertaken safely and more efficiently in the primary care sector.
Authors' methods: Systematic review
Project Status: Completed
Year Published: 1998
English language abstract: An English language summary is available
Publication Type: Not Assigned
Country: England
MeSH Terms
  • Enzyme Inhibitors
  • Penile Erection
  • Piperazines
Organisation Name: West Midlands Health Technology Assessment Collaboration
Contact Address: Elaena Donald-Lopez, West Midlands Health Technology Assessment Collaboration, Department of Public Health and Epidemiology, University of Birmingham, Edgbaston, Birmingham B15 2TT Tel: +44 121 414 7450; Fax: +44 121 414 7878
Contact Name:
Contact Email:
Copyright: University of Birmingham
This is a bibliographic record of a published health technology assessment from a member of INAHTA or other HTA producer. No evaluation of the quality of this assessment has been made for the HTA database.