Authors' objectives: To determine the test’s capacity to rule out the disease through weighted estimate of performance diagnostics parameters as for the 16 slices equipment as the 64 one, as well as to determine direct, real costs related to performing MSCT of 16 and 64 detection slices and invasive coronary angiography and evaluating the cost-effectiveness ratio.

Authors' results and conclusions: 30 studies assessing 16 scanner equipments were retrieved. 4 of them evaluated 64 slices equipments and there is also a technology assessment report. Although the quality of the studies was mostly good, they presented methodological flaws related to selection of patients with high prevalence of the disease, vessels with small calibre’s exclusion or with low imaging quality and the unit of analysis based on the segments. The studies evaluating 16 scanner equipments on the basis of the number of patients (N=757) reached the following figures for sensitivity, specificity, positive and negative verisimilitude ratio 0.94 (CI95%=0.92-0.96), 0.78 (CI95%=0.72-0.83), 4.37 (CI95%=2.74-6.98) and 0.07 (CI95%=0.03-0.16), respectively. The parameters for 64 slices equipments (N=188) were: 0.98 (CI95%=0.94-0.99), 0.94 (CI95%=0.84-0.98), 12.92 (CI95%=5.47-30.53) and 0.03 (CI95%=0.01-0.08), respectively.

Authors' recommendations: The procedure is highly capable of ruling out the coronary disease in population, above all the 64 slices equipments as performed in population with high disease prevalence. Nonetheless, it does not visualize the coronary tree wholly, it has some adverse effects and results in health or changes in managing patients were left unstudied. The selection of the most cost-effective test depends on the context it is performed in. The most cost-effective strategy was 64 slices MSCT for prevalences of 56% and invasive coronary angiography for prevalences of 70%.

Authors' methods: Review

Project Status: Completed

URL for project: https://www.aetsa.org/publicacion/coronariografia-por-tomografia-computarizada-multicorte/

Year Published: 2006

URL for published report: https://www.aetsa.org/download/publicaciones/antiguas/AETSA_2006_F1_Coronariografia_mult.pdf

English language abstract: An English language summary is available

Publication Type: Not Assigned

Country: Spain

Organisation Name: Andalusian Health Technology Assessment Area

Contact Address: Area de Evaluacion de Tecnologias Sanitarias Sanitarias de Andalucia (AETSA) Avda. Innovación, s/n Edificio Arena 1. Sevilla (Spain) Tel. +34 955 006 309

Contact Name: aetsa.csalud@juntadeandalucia.es

Contact Email: aetsa.csalud@juntadeandalucia.es

Copyright: Andalusian Agency for Health Technology Assessment (AETSA)