Tandem mass spectrometry for metabolic disease screening of newborns

Record ID 32008000039
Authors' objectives:

Tandem mass spectrometry (MS/MS) is an assay technique; two mass spectrometers are used to extract and analyze the molecular composition of blood. This technique identifies and quantifies the analytes based on their molecular mass and charge. MS/MS can be used to detect inborn errors of metabolism as part of routine neonatal screening; the objective of neonatal screening is to detect metabolic disorders early and institute treatment, such as dietary intervention, before damage occurs. This technique can detect amino acid metabolic disorders, urea cycle disorders, fatty acid oxidation disorders, and organic acid metabolic disorders.

Authors' methods: Review
Project Status: Completed
URL for project: http://www.hayesinc.com/
Year Published: 2007
English language abstract: An English language summary is available
Publication Type: Not Assigned
Country: United States
MeSH Terms
  • Infant, Newborn
  • Mass Screening
  • Tandem Mass Spectrometry
  • Metabolic Diseases
Organisation Name: HAYES, Inc.
Contact Address: 157 S. Broad Street, Suite 200, Lansdale, PA 19446, USA. Tel: 215 855 0615; Fax: 215 855 5218
Contact Name: saleinfo@hayesinc.com
Contact Email: saleinfo@hayesinc.com
Copyright: HAYES, Inc.
This is a bibliographic record of a published health technology assessment from a member of INAHTA or other HTA producer. No evaluation of the quality of this assessment has been made for the HTA database.